Eltriz Plus Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of face, lips, or throat
- Difficulty breathing or wheezing
- Severe skin rash with blisters or peeling
- Yellowing of eyes or skin
- Dark urine or severe abdominal pain
- Extreme drowsiness or confusion
- Fast or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is eltriz plus tablet used for?
This medicine is a combination of levocetirizine (an antihistamine) and ambroxol (a mucolytic) used to treat allergic symptoms with cough and mucus. It relieves sneezing, runny nose, and thins mucus to ease expectoration. It is taken orally, usually once or twice daily, as prescribed by a doctor.
- Generic Name: Levocetirizine (5mg) + Ambroxol (2.5mg)
- Manufacturer: Serin Formulations Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 eltriz plus tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लेवोसेटिरिज़िन और एम्ब्रोक्सोल का संयोजन है। इसका उपयोग एलर्जी के लक्षणों जैसे छींक, नाक बहना, खुजली और गले में कफ जमने के कारण होने वाली खांसी के इलाज में किया जाता है। लेवोसेटिरिज़िन एलर्जी को कम करता है और एम्ब्रोक्सोल कफ को पतला करके बाहर निकालने में मदद करता है। यह दवा मुंह से ली जाती है और डॉक्टर के निर्देशानुसार दिन में एक या दो बार ली जा सकती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, थकान, और हल्का पेट दर्द शामिल हैं। कुछ लोगों को चक्कर आना या सिरदर्द भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई, या त्वचा पर गंभीर दाने हों तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा न बढ़ाएं या घटाएं। इस दवा के साथ शराब न लें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। अगर आपको किडनी या लीवर की समस्या है तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के इस दवा का सेवन न करें। दवा को बच्चों की पहुंच से दूर रखें और कमरे के तापमान पर स्टोर करें।
💊 eltriz plus tablet Uses & Benefits
[{"condition":"Allergic rhinitis with productive cough","description":"This medicine helps relieve sneezing, runny nose, itching, and watery eyes while also thinning mucus to ease cough.","evidence":"Well-established for individual components; combination use is common in clinical practice."},{"condition":"Upper respiratory tract infections with allergic component","description":"Used to reduce allergic symptoms and help clear mucus in conditions like common cold with cough.","evidence":"Commonly prescribed, though evidence for combination is limited."},{"condition":"Chronic bronchitis with mucus hypersecretion","description":"Ambroxol helps in mucolysis, while levocetirizine may reduce associated allergic symptoms.","evidence":"Ambroxol is well-established as a mucolytic; levocetirizine is established for allergic symptoms."}]
Off-label uses: [{"condition":"Post-nasal drip","description":"Sometimes used to reduce post-nasal drip and associated cough, though not a labeled indication.","evidence":"Limited"},{"condition":"Sinusitis with allergic rhinitis","description":"May be used to alleviate allergic symptoms and thin mucus in sinusitis, but not a primary treatment.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis with productive cough
Also treats: Upper respiratory tract infections with allergic component, Chronic bronchitis with mucus hypersecretion
📋 Drug Information
| Generic Name(s) | Levocetirizine (5mg) + Ambroxol (2.5mg) |
| Brand Name | eltriz plus tablet |
| Manufacturer | Serin Formulations Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Levocetirizine is the active enantiomer of cetirizine and acts as a selective peripheral H1-receptor antagonist. It binds to histamine H1 receptors, preventing histamine from triggering allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. Ambroxol is a mucolytic agent that increases serous bronchial secretion, reduces mucus viscosity, and promotes ciliary clearance. It also has local anesthetic and antioxidant properties. Together, they address allergic symptoms and mucus congestion.
Mechanism Steps
💡 How to Take eltriz plus tablet
Strength: Each tablet contains levocetirizine 5 mg and ambroxol 2.5 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once or twice daily, depending on the severity of symptoms and the prescribing doctor's judgment. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Take with or without food. If you have kidney or liver problems, your doctor may adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the sedative effects of levocetirizine. Dose adjustment may be necessary based on renal function. The dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, dose reduction is recommended. For creatinine clearance 30-50 mL/min, the dose may be reduced to one tablet once daily. For creatinine clearance 10-30 mL/min, one tablet every other day may be appropriate. For creatinine clearance <10 mL/min, use is not recommended. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution and under medical supervision. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet twice daily, but this should not be exceeded without medical advice. The maximum daily dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of eltriz plus tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Opioids | Major | |
| Ritonavir | Moderate | |
| Theophylline | Moderate | |
| Anticholinergics | Minor |
🚨 Major Interactions
- Alcohol
- CNS depressants (e.g., benzodiazepines, opioids)
⚡ Moderate Interactions
- Ritonavir
- Theophylline
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can enhance the sedative effects of levocetirizine, leading to increased drowsiness, dizziness, and impaired coordination. This can affect your ability to drive or operate machinery. If you consume alcohol regularly, discuss it with your doctor before taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to levocetirizine, ambroxol, or any component of the formulation","Severe renal impairment (creatinine clearance < 10 mL/min) without specialist supervision","Children under 6 years of age (safety and efficacy not established)","Pregnancy (first trimester for ambroxol; consult doctor)","Breastfeeding without medical advice"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Use with caution in patients with liver disease.","Do not exceed the recommended dose.","If symptoms persist or worsen after 7 days, consult your doctor.","Rare severe skin reactions have been reported with ambroxol; stop and seek medical help if rash occurs.","Elderly patients may be more sensitive to sedative effects.","Not recommended for children under 6 years without medical advice."]
🤱 Lactation Safety
Levocetirizine is excreted in breast milk in small amounts and may cause drowsiness in the infant. Ambroxol is also excreted in breast milk. This medicine should be used during breastfeeding only if the potential benefit justifies the potential risk to the infant. Consult your doctor.
💊 Overdose Management
Overdose of this medicine may cause increased drowsiness, dizziness, nausea, and in severe cases, agitation or seizures. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Avoid alcohol and other central nervous system depressants while taking this medicine, as they can increase drowsiness. If you have kidney or liver problems, inform your doctor before taking this medicine, as dose adjustment may be needed. Do not use this medicine for longer than recommended without a follow-up evaluation. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight. Do not use it after the expiry date. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Never double the dose to catch up. If you experience any signs of an allergic reaction, stop the medicine and seek medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the sedative effects of levocetirizine and may experience increased drowsiness, confusion, or dizziness. Dose adjustment may be needed based on kidney function. Regular monitoring of renal function is advised. Falls risk may increase due to drowsiness; take precautions.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Levocetirizine is generally considered safe, but ambroxol should be avoided in the first trimester. Your doctor may recommend alternative treatments if needed.
🏥 Post-Surgery Considerations
After surgery, inform your surgeon and anesthesiologist about this medicine. It may interact with anesthetic agents and increase sedation. Your doctor may advise stopping it before surgery. Do not resume without medical advice.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may cause dry mouth, which can affect dental health. Also, the sedative effect may interact with sedatives used in dental procedures. Your dentist may recommend adjusting the dose or timing.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience drowsiness or dizziness. Avoid strenuous exercise or activities that require full alertness until you know how the medicine affects you. If you feel dizzy or weak, stop exercising and rest. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. It is advisable to avoid such activities until you know how the medicine affects you. If your work involves operating heavy equipment, inform your employer and doctor. The sedative effect may diminish after a few days of use.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects such as severe rash, swelling, or difficulty breathing. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of levocetirizine may lead to tolerance or increased sedation in some patients. Ambroxol is generally well-tolerated, but rare liver enzyme elevations have been reported. Regular monitoring of kidney and liver function may be advised, especially in patients with pre-existing conditions. Do not use for extended periods without a doctor's review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help relieve nasal congestion and allergic symptoms without medication.
Evidence: Well-establishedHelps loosen mucus and ease cough.
Evidence: Commonly used, limited evidenceReducing exposure to allergens can decrease the need for medication.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for vaccination, inform your doctor about all medicines you are taking. There is no need to stop this medicine before vaccination unless advised by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If you are crossing time zones, adjust your dosing schedule gradually to avoid missing doses. Keep it in your carry-on luggage if flying. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Levocetirizine starts relieving allergic symptoms within 1 hour, while ambroxol's mucolytic effect may take a few hours to become noticeable.
A: Consult your doctor before combining with other cold medicines, as they may contain overlapping ingredients or interact.
A: Consult your doctor. Levocetirizine is generally considered safe when needed, but ambroxol is often avoided in the first trimester.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is an antibiotic.
Fact: This medicine is not an antibiotic. It contains an antihistamine and a mucolytic, which treat allergic symptoms and mucus, not bacterial infections. - Myth: It can be taken for any type of cough.
Fact: It is specifically for cough associated with allergies and thick mucus. It is not effective for dry cough or cough due to other causes. - Myth: It is safe to take long-term without supervision.
Fact: Long-term use should be monitored by a doctor, especially in patients with kidney or liver problems.
🔄 Alternative Options
Generic Alternatives
- Levocetirizine + Ambroxol combination generics available
Brand Alternatives
- Eltriz Plus Tablet