Aviglen MF Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Symptoms of lactic acidosis: rapid breathing, muscle pain, extreme tiredness, dark urine.
- Severe hypoglycemia: confusion, seizures, loss of consciousness.
- Signs of allergic reaction: rash, swelling of face or throat, difficulty breathing.
- Yellowing of skin or eyes (jaundice).
- Unusual bleeding or bruising.
- Persistent nausea, vomiting, or severe abdominal pain.
If experiencing severe symptoms, call emergency services immediately.
What is elglib m 5mg/500mg tablet used for?
This medicine is a combination of Glibenclamide and Metformin used to treat type 2 diabetes. It lowers blood sugar by increasing insulin release and improving insulin sensitivity. It is taken orally with meals, usually once or twice daily.
- Generic Name: Glibenclamide (5mg) + Metformin (500mg)
- Manufacturer: Suraksha Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 elglib m 5mg/500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ग्लिबेंक्लामाइड और मेटफॉर्मिन का संयोजन है, जिसका उपयोग टाइप 2 डायबिटीज के इलाज में किया जाता है। यह रक्त शर्करा को कम करने में मदद करती है जब अकेले मेटफॉर्मिन से पर्याप्त नियंत्रण नहीं होता। यह इंसुलिन स्राव बढ़ाती है और शरीर की इंसुलिन संवेदनशीलता में सुधार करती है। इसे भोजन के साथ लेना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में कम रक्त शर्करा (हाइपोग्लाइसीमिया), मतली, दस्त, पेट की गड़बड़ी और मुँह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभावों में लैक्टिक एसिडोसिस और गंभीर हाइपोग्लाइसीमिया शामिल हैं। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ लें। खाली पेट न लें। शराब का सेवन बिल्कुल न करें। नियमित रूप से रक्त शर्करा की जांच करें। कम शर्करा के लक्षणों के लिए ग्लूकोज की गोलियाँ या मिठाई साथ रखें। बिना डॉक्टर की सलाह के दवा की खुराक न बदलें।
💊 elglib m 5mg/500mg tablet Uses & Benefits
[{"condition":"Type 2 diabetes mellitus","description":"Used as an add-on therapy in adults whose blood sugar is not controlled by metformin alone, or when metformin is not suitable.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Type 2 diabetes mellitus
Also treats: Obesity, Metabolic syndrome, Polycystic ovary syndrome (off-label)
📋 Drug Information
| Generic Name(s) | Glibenclamide (5mg) + Metformin (500mg) |
| Brand Name | elglib m 5mg/500mg tablet |
| Manufacturer | Suraksha Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antidiabetic agents with complementary mechanisms. Glibenclamide binds to ATP-sensitive potassium channels on pancreatic beta cells, causing depolarization and insulin release. Metformin decreases hepatic glucose production, reduces intestinal glucose absorption, and improves insulin sensitivity in peripheral tissues.
Mechanism Steps
💡 How to Take elglib m 5mg/500mg tablet
Strength: Tablet containing Glibenclamide 5 mg and Metformin 500 mg.
Dosage Information
| Adult Dosage | The usual starting dose is one tablet taken once or twice daily with meals. The dose may be adjusted by your doctor based on blood sugar levels, kidney function, and tolerability. The maximum daily dose is generally 4 tablets (20 mg glibenclamide and 2000 mg metformin). Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the effects of this medicine and are at higher risk of hypoglycemia and lactic acidosis. Start with a low dose and titrate slowly. Regular monitoring of kidney function is essential. Dose must be individualized by a qualified clinician. |
| Renal Impairment | This medicine is contraindicated in severe renal impairment (eGFR <30 mL/min/1.73 m2). In mild to moderate renal impairment, dose reduction and close monitoring are required. Consult your doctor for dose adjustment. |
| Hepatic Impairment | Use with caution in mild to moderate liver disease. Contraindicated in severe liver disease. Dose adjustment may be needed. Consult your doctor. |
| Maximum Daily Dose | Maximum daily dose is 20 mg glibenclamide and 2000 mg metformin (4 tablets). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of elglib m 5mg/500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Beta-blockers | Major | |
| MAOIs | Major | |
| Iodinated contrast media | Major | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| ACE inhibitors | Moderate | |
| NSAIDs | Moderate | |
| Antacids | Minor | |
| Cimetidine | Minor |
🚨 Major Interactions
- Alcohol
- Beta-blockers
- Monoamine oxidase inhibitors (MAOIs)
- Contrast media (iodinated)
⚡ Moderate Interactions
- Diuretics
- Corticosteroids
- ACE inhibitors
- NSAIDs
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. It increases the risk of lactic acidosis, a rare but serious complication, and can cause severe hypoglycemia. It may also worsen liver function.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Risk of hypoglycemia, especially with skipped meals, alcohol, or exercise.","Risk of lactic acidosis, a rare but serious complication. Seek immediate care for symptoms.","Discontinue before surgery or radiological procedures using iodinated contrast and restart only after kidney function is normal.","Avoid alcohol completely.","Monitor kidney and liver function regularly.","May cause vitamin B12 deficiency with long-term use.","Elderly patients are at higher risk of hypoglycemia and lactic acidosis.","Not for use in type 1 diabetes or diabetic ketoacidosis."]
🤱 Lactation Safety
Glibenclamide is excreted in breast milk in small amounts. Metformin is also excreted in breast milk. Consult your doctor before breastfeeding while on this medicine. Monitoring of the infant's blood sugar may be advised.
💊 Overdose Management
Overdose can cause severe hypoglycemia and lactic acidosis. Symptoms include confusion, seizures, rapid breathing, and extreme fatigue. Seek emergency medical attention immediately. Treatment includes glucose administration, hemodialysis for metformin removal, and supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if it is more than half the dosing interval away. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine with meals to reduce the risk of low blood sugar and stomach upset. Do not skip meals while on this medicine. Carry a fast-acting sugar source like glucose tablets or candy to treat hypoglycemia. Avoid alcohol as it can increase the risk of lactic acidosis and low blood sugar. Inform your doctor about all other medicines you take, especially those for blood pressure, heart, or infections. Do not change the dose without consulting your doctor. Monitor your blood sugar regularly as advised. Report symptoms like unusual tiredness, muscle pain, difficulty breathing, or dark urine immediately, as these may indicate lactic acidosis.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of hypoglycemia and lactic acidosis. Start with a low dose and monitor kidney function regularly. Avoid skipping meals.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning pregnancy, consult your doctor to switch to insulin or other safer options. Maintain good blood sugar control before conception.
🏥 Post-Surgery Considerations
This medicine may need to be temporarily stopped before surgery, especially if iodinated contrast is used. Consult your surgeon and doctor. Blood sugar should be monitored closely during recovery.
🦷 Dental Procedures
Inform your dentist about this medicine. Hypoglycemia can occur during dental procedures if you skip meals. Take your medicine with food as usual unless advised otherwise.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise can lower blood sugar. Monitor your blood sugar before and after exercise. Carry a fast-acting sugar source. Adjust medication timing with your doctor if you exercise regularly.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause hypoglycemia, which can impair your ability to drive or operate machinery. Do not drive if you feel symptoms of low blood sugar. Take breaks and eat regularly during work hours.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping suddenly can cause blood sugar to rise. Your doctor may adjust or stop it based on your condition, kidney function, or side effects.
📅 Long-Term Use Effects
Long-term use may lead to vitamin B12 deficiency, requiring annual monitoring. Kidney function should be checked regularly. Weight gain and hypoglycemia are possible. Cardiovascular risk should be assessed. Regular follow-up with your doctor is essential.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise can help control blood sugar and may reduce medication needs.
Evidence: Well-establishedDPP-4 inhibitors, SGLT2 inhibitors, or GLP-1 agonists may be alternatives.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, infections can worsen blood sugar control. Keep vaccinations up to date, especially influenza and pneumococcal vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. If traveling across time zones, consult your doctor for dose timing adjustments. Carry extra doses in case of delays. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within a few hours, but full effects on HbA1c may take 2-3 months.
A: It depends on the severity. It is contraindicated in severe kidney disease. Consult your doctor.
A: Take fast-acting sugar like glucose tablets, candy, or juice immediately. If symptoms persist, seek medical help.
🤔 Common Patient Concerns
🔄 Substitutes for elglib m 5mg/500mg tablet
View AllAlternative brands with exact same active ingredient:
-
dynil forte 5 mg/500 mg tabletZydus Healthcare Limited ₹8.75 91.6% CHEAPER
-
galmin 5mg/500mg tabletSai Mirra Innopharm Pvt Ltd ₹10.78 89.6% CHEAPER
-
davaindia glibenclamide+metformin 5mg/500mg tabletDavaindia Generic Pharmacy ₹11.00 89.4% CHEAPER
-
glycurb forte 5 mg/500 mg tabletWin-Medicare Pvt Ltd ₹12.19 88.3% CHEAPER
-
metica g 5 mg/500 mg tabletAbbott ₹12.71 87.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps manage blood sugar but does not cure diabetes. Lifestyle changes and ongoing treatment are essential. - Myth: I can stop taking this medicine once my sugar is normal.
Fact: Stopping suddenly can cause blood sugar to rise. Always consult your doctor before stopping. - Myth: This medicine is safe for everyone with diabetes.
Fact: It is not for type 1 diabetes or people with severe kidney or liver disease.
🔄 Alternative Options
Generic Alternatives
- Glibenclamide + Metformin generic tablets
Brand Alternatives
- Glimestar M1
- Glynase MF
- Daonil M
- Glimisave M1
- Zoryl M1