aride 50mg tablet - Amisulpride (50mg) medicine

Aride 50mg Tablet - Uses, Price, Side Effects

4.2 (10 reviews)

Amisulpride (50mg)

🏭 Suraksha Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is aride 50mg tablet used for?

Aride 50mg Tablet contains Amisulpride, an atypical antipsychotic used to treat schizophrenia, particularly negative symptoms like social withdrawal and lack of emotion. It works by blocking dopamine receptors in the brain, helping to restore chemical balance and reduce psychotic symptoms.

Generic Name: Amisulpride
Manufacturer: Suraksha Pharma Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 aride 50mg tablet Uses & Benefits

Schizophrenia (positive and negative symptoms); acute psychotic episodes; maintenance therapy.

Off-label uses: Bipolar depression, anxiety disorders, obsessive-compulsive disorder (limited evidence).

📋 Drug Information

Generic Name(s)	Amisulpride
Brand Name	Amisant 200 Tablet
Manufacturer	Suraksha Pharma Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Atypical Antipsychotics
Route of Administration	Oral
Storage	Store at room temperature (15-30°C), protected from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration, with peak plasma concentrations reached within 1-4 hours. Bioavailability is approximately 48% due to first-pass metabolism.

DistributionWidely distributed throughout the body; crosses the blood-brain barrier. Volume of distribution is about 5.8 L/kg.

Protein BindingApproximately 16% bound to plasma proteins.

MetabolismMetabolized in the liver, primarily via CYP3A4, to inactive metabolites. Minor metabolism via other pathways.

Half-LifeApproximately 12 hours (range 10-14 hours).

ExcretionPrimarily excreted in urine (about 70% as unchanged drug and metabolites) and feces (about 20%).

Bioavailability48%

Onset of ActionTherapeutic effects may be observed within a few days to weeks, but full antipsychotic effect may ta

Peak Plasma Time1-4 hours

Duration of ActionApproximately 24 hours due to once-daily dosing.

How It Works

Selective antagonist at dopamine D2 and D3 receptors, with higher affinity for D3 receptors. It also has some antagonistic activity at serotonin 5-HT2A receptors.

Mechanism Steps

1Amisulpride selectively binds to dopamine D2 and D3 receptors, with higher affinity for D3.

2Blocks dopamine receptors in the mesolimbic system, reducing positive symptoms of schizophrenia.

3At low doses, preferentially blocks presynaptic D2/D3 autoreceptors, increasing dopamine release in prefrontal cortex, improving negative symptoms.

💡 How to Take aride 50mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of aride 50mg tablet

✅ Common Side Effects

Insomnia
Anxiety
Agitation
Weight gain
Constipation
Nausea
Dry mouth
Sedation

🚨 Serious Side Effects

QT prolongation
Torsades de pointes
Neuroleptic malignant syndrome
Seizures
Tardive dyskinesia
Prolactin elevation (galactorrhea, gynecomastia)

⚠️ Rare Side Effects

Hepatotoxicity
Agranulocytosis
Venous thromboembolism
Pancreatitis
Allergic reactions

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Levodopa	Major	Reduced efficacy of levodopa
Alcohol	Moderate	Increased CNS depression
Antihypertensives	Moderate	Enhanced hypotensive effect

🚨 Major Interactions

Levodopa
Dopamine agonists
QT-prolonging drugs
CYP3A4 inhibitors

⚡ Moderate Interactions

Antihypertensives
CNS depressants
Lithium

ℹ️ Minor Interactions

Antacids
Cimetidine

🍽️ Food Interactions

Food may delay absorption but does not significantly affect bioavailability.

🍷 Alcohol Interaction

Alcohol may enhance CNS depressant effects; avoid concurrent use.

🛡️ Safety & Warnings

Liver

Low

Kidney

Moderate

Heart

Moderate

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to amisulpride; concomitant use with prolactin-dependent tumors; known QT prolongation; severe renal impairment (CrCl <10 mL/min); pheochromocytoma.

📊 Monitoring Parameters

ECG (QT interval), blood pressure, liver function tests, renal function, prolactin levels, extrapyramidal symptoms.

🤱 Lactation Safety

Not recommended; amisulpride is excreted in breast milk and may cause adverse effects in the infant.

💊 Overdose Management

Supportive care; ECG monitoring; activated charcoal if recent ingestion; no specific antidote; treat arrhythmias as needed.

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for aride 50mg tablet

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Alternative brands with exact same active ingredient (Amisulpride (50mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.