Uphold Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Erection lasting more than 4 hours
- Sudden vision loss or blurred vision
- Sudden hearing loss or ringing in the ears
- Chest pain or difficulty breathing
- Severe dizziness or fainting
- Signs of serotonin syndrome such as agitation, hallucinations, fast heartbeat, fever, or muscle twitching
- Severe skin rash or blistering
If experiencing severe symptoms, call emergency services immediately.
What is edon-d tablet used for?
This medicine is a combination of tadalafil and dapoxetine used to treat premature ejaculation in adult men. It works by improving blood flow to the penis and delaying ejaculation. It is taken as needed, about 1 to 3 hours before sexual activity, and should not be taken more than once in 24 hours.
- Generic Name: Tadalafil (10mg) + Dapoxetine (30mg)
- Manufacturer: Eskag Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 edon-d tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टैडालाफिल 10 मिलीग्राम और डैपोक्सेटीन 30 मिलीग्राम का संयोजन है, जिसका उपयोग वयस्क पुरुषों में शीघ्रपतन (प्रीमैच्योर इजैकुलेशन) के इलाज के लिए किया जाता है। यह दवा लिंग में रक्त के प्रवाह को बढ़ाकर और स्खलन में देरी करके काम करती है। इसे सेक्सुअल गतिविधि से लगभग 1 से 3 घंटे पहले लिया जाता है और 24 घंटे में एक बार से अधिक नहीं लेना चाहिए। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, जी मिचलाना, चेहरे पर लालिमा और अपच शामिल हैं। कुछ पुरुषों को नींद आना, थकान, नाक बंद होना या मूड में बदलाव का अनुभव हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको लंबे समय तक इरेक्शन (4 घंटे से अधिक), अचानक दृष्टि या सुनने में कमी, सीने में दर्द, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को केवल योग्य डॉक्टर की सलाह पर ही लें। नाइट्रेट या सीने में दर्द की दवाओं के साथ इसका सेवन न करें, क्योंकि इससे रक्तचाप खतरनाक रूप से गिर सकता है। शराब से बचें, क्योंकि इससे चक्कर आना, नींद आना और बेहोशी का खतरा बढ़ सकता है। जब तक आपको पता न चले कि यह दवा आप पर कैसे असर करती है, तब तक वाहन न चलाएं। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। 24 घंटे में एक बार से अधिक इस दवा का सेवन न करें।
💊 edon-d tablet Uses & Benefits
[{"condition":"Premature ejaculation","description":"This medicine is used to treat premature ejaculation in adult men by delaying ejaculation and improving control over the timing of ejaculation.","evidence":"Well-established for dapoxetine component; combination use is supported by clinical experience."},{"condition":"Erectile dysfunction with premature ejaculation","description":"The tadalafil component helps improve erectile function, which is often affected in men with premature ejaculation.","evidence":"Well-established for tadalafil component; combination use is supported by clinical experience."}]
Off-label uses: [{"condition":"Premature ejaculation with mild erectile difficulty not responding to single-agent therapy","description":"Some clinicians may prescribe this combination when a single medicine does not provide adequate control of both conditions.","evidence":"Limited"}]
Primary treatment for: Premature ejaculation
Also treats: Erectile dysfunction
📋 Drug Information
| Generic Name(s) | Tadalafil (10mg) + Dapoxetine (30mg) |
| Brand Name | edon-d tablet |
| Manufacturer | Eskag Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | SEX STIMULANTS REJUVENATORS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) away from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | Not established from the available information. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Tadalafil inhibits phosphodiesterase type 5, which increases cyclic guanosine monophosphate in the corpus cavernosum, leading to smooth muscle relaxation and increased blood flow to the penis during sexual stimulation. Dapoxetine inhibits the reuptake of serotonin in the central nervous system, which increases serotonin levels at the synapse and helps delay the ejaculatory reflex. The combination addresses both erectile function and ejaculatory control.
Mechanism Steps
💡 How to Take edon-d tablet
Strength: Tadalafil 10 mg + Dapoxetine 30 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally about 1 to 3 hours before anticipated sexual activity. Do not take more than one tablet in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Use with caution in elderly patients. Dose adjustment may be necessary based on renal and hepatic function. Consult a doctor. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor. |
| Maximum Daily Dose | One tablet in 24 hours. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of edon-d tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Nitrates | Major | |
| MAOIs | Major | |
| Thioridazine | Major | |
| CYP3A4 inhibitors | Moderate | |
| Alpha-blockers | Moderate | |
| SSRIs/SNRIs | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Nitrates (e.g., nitroglycerin, isosorbide mononitrate)
- Monoamine oxidase inhibitors (MAOIs)
- Thioridazine
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin)
- Alpha-blockers (e.g., tamsulosin, doxazosin)
- Other serotonergic drugs (e.g., SSRIs, SNRIs, triptans, tramadol)
🍷 Alcohol Interaction
Alcohol can increase the risk of dizziness, drowsiness, fainting, and low blood pressure when taken with this medicine. It is best to avoid alcohol or limit intake while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Concurrent use of nitrates","Concurrent use of MAOIs","Concurrent use of thioridazine","Severe cardiovascular disease","History of fainting","Severe hepatic impairment","Severe renal impairment","Known hypersensitivity to tadalafil or dapoxetine"]
⚠️ Warnings & Precautions
["Do not take with nitrates or recreational drugs containing nitrates.","Avoid alcohol while taking this medicine.","Do not drive or operate machinery until you know how it affects you.","Inform your doctor about all other medicines you are taking.","Seek immediate medical help if you experience sudden vision or hearing loss.","Seek immediate medical help if you have an erection lasting more than 4 hours.","Use with caution in patients with bleeding disorders or active peptic ulcer.","Use with caution in patients with glaucoma or raised intraocular pressure."]
🤱 Lactation Safety
This medicine is not intended for use in women. It is not indicated for use during breastfeeding.
💊 Overdose Management
Overdose may cause severe hypotension, serotonin syndrome, or prolonged erection. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
This medicine is taken as needed, not on a fixed schedule. If you miss a dose, take it as soon as you remember if you still anticipate sexual activity. Do not take more than one dose in 24 hours.
Additional Safety Advice
Take this medicine only under the supervision of a qualified doctor. Do not take it with nitrates, recreational drugs such as amyl nitrite, or any medicine for chest pain, as this can cause a dangerous drop in blood pressure. Avoid alcohol, as it can increase drowsiness, dizziness, and the risk of fainting. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor about all other medicines you take, especially antidepressants, antifungals, antibiotics, and blood pressure medicines. Do not take more than the prescribed dose, and do not take it more than once in 24 hours. If you have a history of fainting, low blood pressure, bleeding disorders, or liver or kidney disease, tell your doctor before starting this medicine. Keep this medicine out of the reach of children and store it at room temperature away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Use with caution in elderly patients. Dose adjustment may be necessary based on renal and hepatic function. Monitor blood pressure and for signs of dizziness or fainting.
🤰 Pregnancy Planning (TTC)
This medicine is not intended for use in women. It is not indicated for use during pregnancy planning.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, especially if you have recently had cardiovascular or ocular surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, especially before any surgical dental procedure, as it may affect blood pressure and bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting if you experience dizziness or low blood pressure. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It should not interfere with most desk jobs, but caution is advised.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience serious side effects such as prolonged erection, sudden vision or hearing loss, or signs of serotonin syndrome. Do not stop prescribed medicines without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Regular monitoring of blood pressure, mood, and sexual function is advised. There is limited information on the long-term safety of the combination. Do not use for prolonged periods without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Techniques such as stop-start and squeeze methods can help manage premature ejaculation.
Evidence: Well-establishedLidocaine or prilocaine sprays can reduce penile sensitivity and delay ejaculation.
Evidence: ModerateStrengthening pelvic floor muscles may improve ejaculatory control.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature away from moisture and direct sunlight. If traveling across time zones, take the medicine as needed for sexual activity, but do not exceed one dose in 24 hours. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 1 to 2 hours, but the full effect may take up to 3 hours. It is taken about 1 to 3 hours before anticipated sexual activity.
A: No, this medicine is taken as needed, not daily. Do not take more than one tablet in 24 hours.
A: Avoid alcohol, nitrates, and recreational drugs. Do not drive or operate machinery until you know how it affects you.
🤔 Common Patient Concerns
🔄 Substitutes for edon-d tablet
View AllAlternative brands with exact same active ingredient:
-
matfil 10 d tabletMatias Healthcare Pvt Ltd ₹139.69 75.8% CHEAPER
-
tadafil d 10mg/30mg tabletD D Pharmaceuticals ₹183.80 68.1% CHEAPER
-
depofil tabletR B Pharmaceuticals ₹187.50 67.5% CHEAPER
-
bigfun gold 10mg/30mg tabletLeeford Healthcare Ltd ₹188.12 67.4% CHEAPER
-
dapodafil tabletBioceutics Inc ₹196.88 65.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken daily for better results.
Fact: This medicine is taken as needed, not daily. Taking it more than once in 24 hours can increase the risk of side effects. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol can increase the risk of dizziness, drowsiness, and low blood pressure. It is best to avoid alcohol. - Myth: This medicine can be taken with nitrates for chest pain.
Fact: This medicine is absolutely contraindicated with nitrates due to the risk of severe hypotension.
🔄 Alternative Options
Generic Alternatives
- Tadalafil 10 mg + Dapoxetine 30 mg tablet