Ecogat A 75 mg/400 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden severe pain, swelling, or inability to move a joint (possible tendon rupture).
- Numbness, tingling, or burning in hands or feet (peripheral neuropathy).
- Seizures, confusion, or hallucinations.
- Difficulty breathing, swelling of face, lips, or throat (anaphylaxis).
- Yellowing of skin or eyes, dark urine, or severe abdominal pain (liver damage).
- Irregular heartbeat, fainting, or palpitations (QT prolongation).
- Severe diarrhea with blood or mucus (C. difficile infection).
If experiencing severe symptoms, call emergency services immediately.
What is ecogat a 75 mg/400 mg tablet used for?
This medicine is a combination of Ambroxol (a mucolytic) and Gatifloxacin (an antibiotic) used to treat bacterial respiratory infections. It helps loosen mucus and kills bacteria. It is taken once daily for 5-10 days as prescribed.
- Generic Name: Ambroxol (75mg) + Gatifloxacin (400mg)
- Manufacturer: Torrent Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ecogat a 75 mg/400 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एम्ब्रोक्सोल और गैटीफ्लोक्सासिन का संयोजन है, जिसका उपयोग बैक्टीरियल श्वसन संक्रमण के इलाज के लिए किया जाता है। एम्ब्रोक्सोल बलगम को पतला करता है और गैटीफ्लोक्सासिन बैक्टीरिया को मारता है। यह आमतौर पर ब्रोंकाइटिस, निमोनिया और साइनस संक्रमण में दी जाती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, सिरदर्द, चक्कर आना और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभावों में टेंडन टूटना, तंत्रिका क्षति, दौरे और एलर्जी प्रतिक्रिया हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। एंटासिड, आयरन या जिंक सप्लीमेंट के साथ इसे न लें, कम से कम 2 घंटे का अंतर रखें। धूप में जाने से बचें और सनस्क्रीन का उपयोग करें। शराब न पिएं। गाड़ी चलाने से बचें यदि चक्कर आएं। पूरा कोर्स पूरा करें।
💊 ecogat a 75 mg/400 mg tablet Uses & Benefits
[{"condition":"Acute bacterial exacerbation of chronic bronchitis","description":"This medicine helps treat bacterial lung infections and loosens mucus, making it easier to cough out.","evidence":"Well-established"},{"condition":"Bacterial pneumonia","description":"Used to treat community-acquired pneumonia caused by susceptible bacteria, with Ambroxol aiding mucus clearance.","evidence":"Well-established"},{"condition":"Acute bacterial sinusitis","description":"May be prescribed for bacterial sinus infections to reduce infection and thin sinus secretions.","evidence":"Moderate"},{"condition":"Acute otitis media","description":"Sometimes used in adults for middle ear infections, though not first-line.","evidence":"Limited"}]
Off-label uses: [{"condition":"Chronic obstructive pulmonary disease (COPD) exacerbation","description":"May be used off-label for COPD flare-ups with bacterial infection, but not routinely recommended.","evidence":"Limited"}]
Primary treatment for: Bacterial respiratory tract infections
Also treats: Acute exacerbation of chronic bronchitis, Community-acquired pneumonia, Acute bacterial sinusitis
📋 Drug Information
| Generic Name(s) | Ambroxol (75mg) + Gatifloxacin (400mg) |
| Brand Name | ecogat a 75 mg/400 mg tablet |
| Manufacturer | Torrent Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. Fluoroquinolones are generally reserved for infections where other antibiotics are not suitable, due to safety concerns. |
| ICMR Guideline | Not established from the available information. Always follow national antibiotic stewardship guidelines. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Ambroxol works by increasing the production of serous fluid in the airways, reducing mucus viscosity, and promoting ciliary movement, which helps clear mucus. Gatifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, repair, and transcription, leading to bacterial cell death.
Mechanism Steps
💡 How to Take ecogat a 75 mg/400 mg tablet
Strength: Tablet containing Ambroxol 75 mg and Gatifloxacin 400 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (Ambroxol 75 mg + Gatifloxacin 400 mg) taken orally once daily, preferably at the same time each day. The duration of therapy depends on the type and severity of infection, typically 5 to 10 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine is not recommended for children and adolescents under 18 years due to the risk of serious adverse effects on joints and tendons. Consult a pediatrician for appropriate alternatives. |
| Elderly Dosage | Elderly patients (above 65 years) may have reduced renal function and are at higher risk of tendon rupture, CNS effects, and QT prolongation. Dose adjustment may be necessary based on renal function. Use with caution and monitor closely. |
| Renal Impairment | Gatifloxacin is primarily excreted by the kidneys. In patients with renal impairment (creatinine clearance < 40 mL/min), dose adjustment is required. The dose may be reduced or the dosing interval extended. Consult a clinician for specific guidance. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. However, Ambroxol is metabolized in the liver, so caution is advised in patients with severe liver disease. Monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (Ambroxol 75 mg + Gatifloxacin 400 mg) per day. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ecogat a 75 mg/400 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Antacids | Major | |
| Warfarin | Major | |
| NSAIDs | Major | |
| Theophylline | Major | |
| Amiodarone | Major | |
| Corticosteroids | Moderate | |
| Oral hypoglycemics | Moderate | |
| Probenecid | Moderate | |
| Caffeine | Minor | |
| Cyclosporine | Minor |
🚨 Major Interactions
- Antacids, sucralfate, iron, zinc
- Warfarin
- Class IA and III antiarrhythmics (e.g., quinidine, amiodarone)
- NSAIDs (e.g., ibuprofen, naproxen)
- Theophylline
⚡ Moderate Interactions
- Corticosteroids
- Oral hypoglycemics (e.g., glibenclamide)
- Probenecid
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of dizziness, drowsiness, and liver problems. It may also worsen gastrointestinal side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Ambroxol, Gatifloxacin, or other fluoroquinolones","History of tendon disorders related to fluoroquinolone use","Myasthenia gravis","Pregnancy and breastfeeding","Children and adolescents under 18 years","Patients with known QT interval prolongation or uncorrected electrolyte disturbances"]
⚠️ Warnings & Precautions
["Fluoroquinolones, including Gatifloxacin, have been associated with disabling and potentially irreversible serious adverse reactions, including tendinitis, tendon rupture, peripheral neuropathy, and CNS effects. Reserve for patients with no alternative treatment options.","May exacerbate muscle weakness in patients with myasthenia gravis. Avoid use.","Can cause blood sugar disturbances, including severe hypoglycemia. Monitor blood glucose closely in diabetic patients.","May cause photosensitivity. Avoid excessive sun exposure and use sunscreen.","Serious hypersensitivity reactions, including anaphylaxis, can occur. Discontinue immediately if allergic reaction suspected.","Clostridium difficile-associated diarrhea may occur. If diarrhea develops, consider this diagnosis.","Avoid use in patients with a history of QT prolongation or risk factors for arrhythmias."]
🤱 Lactation Safety
Gatifloxacin is excreted in breast milk and may cause serious adverse effects in the nursing infant. It is not recommended during breastfeeding. Consult your doctor for safe alternatives.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of overdose, discontinue the medicine and seek immediate medical attention. Treatment should be symptomatic and supportive. Monitor vital signs, ECG, and electrolytes. Activated charcoal may be considered if ingestion is recent. Hemodialysis does not effectively remove Gatifloxacin from the body.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early. Swallow the tablet whole with a full glass of water. Avoid taking antacids, iron, or zinc supplements within 2 hours before or after this medicine, as they can reduce its absorption. Avoid excessive sunlight and use sunscreen, as this medicine can make your skin more sensitive to UV rays. Do not drive or operate heavy machinery if you feel dizzy. Inform your doctor if you have kidney or liver problems, diabetes, or heart conditions. Avoid alcohol while taking this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, kidney impairment, and CNS effects. Dose adjustment may be needed based on renal function. Monitor closely for any signs of adverse effects.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended for women planning pregnancy or who are pregnant. If you are trying to conceive, consult your doctor for alternative treatments. Fluoroquinolones may affect fetal development.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and increase the risk of tendon problems. Your doctor may adjust the dose or timing.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with certain antibiotics or anesthetics used during dental work. Your dentist may recommend postponing elective procedures until you complete the course.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon rupture. Light activities like walking are generally safe if you feel up to it.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, confusion, or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take rest and avoid strenuous work during the course of treatment.
🛑 When to Stop This Medicine
Stop taking this medicine only after completing the full prescribed course, unless your doctor advises otherwise. If you experience serious side effects like tendon pain, severe allergic reactions, or neurological symptoms, stop immediately and seek medical attention. Do not stop prematurely as it may lead to relapse or resistance.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to the risk of antibiotic resistance and serious side effects such as tendon rupture, peripheral neuropathy, and liver toxicity. It should only be used for the prescribed duration. Regular monitoring of kidney and liver function may be required if used for prolonged periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and relieve congestion naturally.
Evidence: Well-established for symptom reliefCan help clear sinuses and reduce congestion.
Evidence: ModerateTechniques to help clear airway secretions.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are due for any live vaccines, consult your doctor as antibiotics may affect the immune response to certain vaccines. It is generally safe to receive non-live vaccines while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature, away from direct sunlight and moisture. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Declare it at customs if required. Do not pack it in checked luggage; keep it in your carry-on bag.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2-3 days, but you must complete the full course as prescribed.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.
A: If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is not recommended during pregnancy due to potential risks to the fetus. Consult your doctor for alternatives.
A: No, you must complete the full prescribed course to prevent relapse and antibiotic resistance.
🤔 Common Patient Concerns
🔄 Substitutes for ecogat a 75 mg/400 mg tablet
View AllAlternative brands with exact same active ingredient:
-
Respigat 75mg/400mg TabletZydus Cadila ₹45.30 20.2% COSTLIER
-
Floxigat M 75 mg/400 mg TabletMedley Pharmaceuticals ₹54.38 44.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any cough and cold.
Fact: It only works for bacterial infections. Viral colds and coughs do not respond to antibiotics. - Myth: You can stop taking it once you feel better.
Fact: You must complete the full course to prevent relapse and antibiotic resistance. - Myth: It is safe to take with antacids.
Fact: Antacids reduce the absorption of Gatifloxacin. Separate by at least 2 hours.
🔄 Alternative Options
Generic Alternatives
- Ambroxol + Gatifloxacin combination (generic)
Brand Alternatives
- Ecogat A 75 mg/400 mg tablet