e cin 250mg capsule - Erythromycin (250mg) medicine

Althrocin Forte 250mg Syrup: Complete Medicine Guide

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🏭 TOSC International Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of face, lips, tongue, or throat, difficulty breathing.
  • Signs of liver problems: yellowing of skin or eyes, dark urine, severe abdominal pain.
  • Severe or bloody diarrhea, which may indicate C. difficile infection.
  • Hearing loss or ringing in the ears.
  • Irregular heartbeat, palpitations, or fainting.
  • Severe skin rash with blisters or peeling.

If experiencing severe symptoms, call emergency services immediately.

What is e cin 250mg capsule used for?

This medicine is an antibiotic syrup containing erythromycin, used to treat bacterial infections such as respiratory tract infections, skin infections, and chlamydia. It works by stopping bacterial growth. Take it exactly as prescribed, and complete the full course.

  • Generic Name: Erythromycin (250mg)
  • Manufacturer: TOSC International Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 e cin 250mg capsule के बारे में (Hindi Summary)

उपयोग: यह दवा एक एंटीबायोटिक सिरप है जिसमें एरिथ्रोमाइसिन नामक सक्रिय तत्व होता है। इसका उपयोग बैक्टीरियल संक्रमणों जैसे श्वसन तंत्र के संक्रमण, त्वचा के संक्रमण, और क्लैमाइडिया के इलाज के लिए किया जाता है। यह बैक्टीरिया के विकास को रोककर काम करती है। इसे डॉक्टर के निर्देशानुसार ही लें और पूरा कोर्स पूरा करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और भूख में कमी शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। कुछ लोगों को सिरदर्द, चक्कर या दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें एलर्जी, सुनने में कमी, दिल की धड़कन में गड़बड़ी और लीवर की समस्या शामिल हो सकती है। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही मापने वाले कप या सिरिंज का उपयोग करें। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है, लेकिन भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। अंगूर का रस और शराब से बचें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। इसे बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 e cin 250mg capsule Uses & Benefits

[{"condition":"Respiratory tract infections","description":"Used to treat infections such as pneumonia, bronchitis, and pertussis caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Effective against many bacterial skin infections, including cellulitis and erysipelas.","evidence":"Well-established"},{"condition":"Chlamydia trachomatis infections","description":"Used as an alternative treatment for uncomplicated genital chlamydia and eye infections in newborns.","evidence":"Well-established"},{"condition":"Diphtheria","description":"Used as an adjunct to antitoxin to eliminate the bacteria and prevent spread.","evidence":"Well-established"},{"condition":"Legionnaires' disease","description":"Effective against Legionella pneumophila, though other macrolides may be preferred.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Gastroparesis","description":"Sometimes used off-label to stimulate stomach emptying in diabetic gastroparesis due to its prokinetic effects.","evidence":"Limited"},{"condition":"Acne vulgaris","description":"May be used off-label for inflammatory acne, but resistance is common.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Skin infections, Chlamydia, Pertussis, Diphtheria

📋 Drug Information

Generic Name(s)Erythromycin (250mg)
Brand Namee cin 250mg capsule
ManufacturerTOSC International Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassMacrolides
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not refrigerate. Keep the bottle tightly closed. Shake well before each use.
Shelf LifeTypically 24 months from the date of manufacture, but check the expiry date on the packaging.
WHO GuidelineErythromycin is included in the WHO Model List of Essential Medicines for the treatment of various bacterial infections, including respiratory tract infections and chlamydia.
ICMR GuidelineThe Indian Council of Medical Research (ICMR) recommends erythromycin as a treatment option for community-acquired pneumonia and other susceptible infections, but emphasizes judicious use to prevent resistance.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always complete the full course of this antibiotic, even if symptoms improve, to prevent recurrence and resistance.
2
Take this medicine with food if it upsets your stomach.
3
Shake the bottle well before each dose to ensure proper mixing.
4
Use a proper measuring device; household spoons are not accurate.
5
Inform your doctor about all other medicines you are taking, as erythromycin interacts with many drugs.
6
Avoid alcohol while taking this medicine to reduce stomach upset and liver risk.
7
If you experience palpitations, dizziness, or fainting, seek medical attention immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Cough with fever
This medicine is commonly prescribed for respiratory tract infections.
Likely Use
✅
Skin redness and swelling
It is used for bacterial skin infections.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary
❌
Headache
This medicine is not a pain reliever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionErythromycin is absorbed from the gastrointestinal tract, but absorption can be variable depending on the formulation and presence of food. The syrup formulation is designed for oral administration and is absorbed in the small intestine. Food may slightly delay absorption but does not significantly reduce the overall extent. The bioavailability of erythromycin base is approximately 30-65% due to first-pass metabolism.
DistributionErythromycin is widely distributed throughout the body, including into the lungs, liver, spleen, kidneys, and other tissues. It crosses the placenta and is excreted in breast milk. It does not penetrate the cerebrospinal fluid well unless the meninges are inflamed. Protein binding is moderate, ranging from 70-90% to plasma proteins, primarily albumin.
Protein Binding70-90% bound to plasma proteins, mainly albumin.
MetabolismErythromycin is extensively metabolized in the liver by the cytochrome P450 enzyme system, particularly CYP3A4. It is demethylated and hydroxylated to inactive metabolites. It also inhibits CYP3A4, which can lead to drug interactions.
Half-LifeThe elimination half-life of erythromycin is approximately 1.5 to 2 hours in individuals with normal renal function, but it may be prolonged in patients with liver disease.
ExcretionErythromycin is primarily excreted in the bile, with a small amount excreted in the urine. Only about 2-5% of an oral dose is excreted unchanged in the urine. The drug is also excreted in breast milk.
BioavailabilityThe bioavailability of erythromycin base is approximately 30-65%, but it can vary depending on the formulation and food intake.
Onset of ActionThe onset of action for erythromycin is typically within 1-2 hours after oral administration, but clinical improvement may take 24-48 hours.
Peak Plasma TimePeak plasma concentrations are usually reached 1-4 hours after oral administration, depending on the formulation and presence of food.
Duration of ActionThe duration of action is approximately 6-12 hours, but it depends on the dosing frequency and the susceptibility of the bacteria.

How It Works

This medicine works by binding to the 50S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis. Specifically, it blocks the translocation step of peptide chain elongation, preventing the bacteria from building essential proteins needed for growth and multiplication. This action is primarily bacteriostatic, meaning it stops bacterial growth, but it can be bactericidal at higher concentrations against certain organisms. The binding is reversible, and the medicine does not affect human cells because human ribosomes are structurally different.

Mechanism Steps

1
Binding to the 50S ribosomal subunit: This medicine binds reversibly to the 50S subunit of the bacterial ribosome, specifically to the 23S rRNA component.
2
Inhibition of translocation: By binding to the 50S subunit, it blocks the translocation of tRNA from the A site to the P site, preventing the addition of new amino acids to the growing peptide chain.
3
Inhibition of protein synthesis: As a result, the bacteria cannot synthesize essential proteins required for cell wall synthesis, metabolism, and replication.
4
Bacterial growth arrest: The inhibition of protein synthesis leads to stasis of bacterial growth, and the bacteria eventually die or are cleared by the immune system.

💡 How to Take e cin 250mg capsule

Strength: Each 5 mL of syrup contains 250 mg of erythromycin.

1Shake the bottle well before each use.
2Use a calibrated measuring cup or syringe to measure the prescribed dose.
3Take with or without food, but taking with food may reduce stomach upset.
4Swallow the syrup directly; do not mix with other liquids unless instructed.
5Wash the measuring device after each use.
6Take at evenly spaced intervals as prescribed.
7Complete the full course even if you feel better.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 250 mg to 500 mg every 6 to 12 hours, depending on the type and severity of the infection. For severe infections, higher doses may be used. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more susceptible to side effects such as hearing loss and heart rhythm disturbances. Dose adjustment may be necessary based on renal and hepatic function. Consult a doctor for individualized dosing.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance <10 mL/min), dose reduction may be necessary. Consult a doctor for individualized dosing.
Hepatic ImpairmentIn patients with severe hepatic impairment, dose reduction or avoidance may be necessary. Monitor liver function closely. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 4 grams, but this should not be exceeded without medical supervision.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels and side effects.
Alcohol
Avoid
May increase stomach upset and liver risk.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of e cin 250mg capsule

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or contains blood, contact your doctor.
Abdominal pain (Common (5-10%))
Take with food. If pain is severe, seek medical advice.
Vomiting (Common (5-10%))
Take with food and drink clear fluids. If vomiting persists, consult your doctor.
Loss of appetite (Common (5-10%))
Eat small, frequent meals. If it continues, talk to your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Hearing loss (Rare (<0.1%))
Report any ringing in the ears or hearing difficulty to your doctor immediately. It is usually reversible upon stopping the medicine.
Heart rhythm disturbances (QT prolongation) (Rare (<0.1%))
Seek medical attention if you experience palpitations, dizziness, or fainting. Avoid use with other QT-prolonging drugs.
Liver toxicity (hepatitis, jaundice) (Rare (<0.1%))
Contact your doctor if you notice yellowing of the skin or eyes, dark urine, or severe abdominal pain.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek medical attention if you develop severe, persistent diarrhea, especially with blood or mucus.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek emergency care if you develop a painful rash with blisters or peeling skin.
Torsades de pointes
Call emergency services if you experience sudden fainting or irregular heartbeat.
Pancreatitis
Seek immediate medical attention if you have severe upper abdominal pain that radiates to your back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Simvastatin Major
Amiodarone Major
Digoxin Moderate
Theophylline Moderate
Carbamazepine Moderate
Oral contraceptives Moderate
Antacids Minor
Rifampin Major
Ketoconazole Major

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
  • Warfarin
  • Statins (e.g., simvastatin, atorvastatin)
  • QT-prolonging drugs (e.g., amiodarone, sotalol, quinidine)

⚡ Moderate Interactions

  • Digoxin
  • Theophylline
  • Carbamazepine
  • Corticosteroids
  • Oral contraceptives

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach upset and liver problems. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to erythromycin or other macrolide antibiotics.","Concurrent use with certain CYP3A4 substrates that can cause serious toxicity (e.g., ergotamine, dihydroergotamine, cisapride, pimozide, terfenadine, astemizole).","History of cholestatic jaundice or hepatic dysfunction associated with prior erythromycin use.","Use with caution in patients with QT prolongation or ventricular arrhythmias."]

⚠️ Warnings & Precautions

["Use with caution in patients with liver disease; monitor liver function.","May cause QT prolongation; avoid in patients with known QT prolongation or electrolyte abnormalities.","May cause hearing loss, especially with high doses or in patients with renal impairment.","Can cause superinfection, including C. difficile-associated diarrhea; monitor for severe diarrhea.","May interact with many drugs; review all concomitant medications.","Not effective against viral infections; do not use for colds or flu.","Complete the full course as prescribed to prevent resistance."]

🤱 Lactation Safety

Erythromycin is excreted in breast milk and may cause diarrhea or thrush in the nursing infant. It is generally considered safe for breastfeeding mothers, but consult your doctor to weigh the benefits and risks. Monitor the infant for any signs of gastrointestinal upset.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, diarrhea, and hearing loss. There is no specific antidote. Treatment is supportive and symptomatic. If overdose is suspected, seek immediate medical attention. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and electrolytes.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop the course early, even if you feel better. Shake the bottle well before each use to ensure the medicine is evenly mixed. Use a proper measuring device to get the correct dose; do not use a kitchen spoon. This medicine is usually taken with or without food, but taking it with food may help reduce stomach upset. Avoid taking it with grapefruit juice or alcohol. Inform your doctor if you have liver or heart problems, or if you are pregnant or breastfeeding. Do not share this medicine with others, even if they have similar symptoms. Store it at room temperature, away from direct sunlight and moisture. Keep out of reach of children. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of side effects such as hearing loss, heart rhythm disturbances, and liver toxicity. Dose adjustment may be needed based on kidney and liver function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Erythromycin is generally considered safe during pregnancy, but the benefits and risks should be discussed with your healthcare provider.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may interact with anesthetics or other medications used during surgery. Your doctor may advise you to stop it before surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with certain antibiotics or anesthetics used in dentistry. Your dentist may need to adjust your treatment plan.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help your body fight infection.
🥗
Get plenty of rest to support your immune system.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Practice good hygiene to prevent the spread of infection.
🧘
Avoid close contact with others while you are contagious.
🌞
Complete the full course of antibiotics as prescribed.

🏋️ Exercise Considerations

You can continue light exercise if you feel up to it, but avoid strenuous activity if you have fever or fatigue. Listen to your body and rest when needed.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to help prevent diarrhea.
Stay hydrated with water and clear fluids.
Avoid spicy and fatty foods if you have stomach upset.
Eat small, frequent meals if you have nausea.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or nausea in some people. If you experience these side effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Most people can continue their daily activities with minimal disruption.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately; they may advise you to stop.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to antibiotic resistance, superinfections such as oral thrush or C. difficile-associated diarrhea, and rarely, liver toxicity or hearing loss. It should only be used for the prescribed duration. If long-term therapy is necessary, regular monitoring of liver function and hearing may be required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Azithromycin

Another macrolide antibiotic with a broader spectrum and less frequent dosing.

Evidence: Well-established
Amoxicillin

A penicillin antibiotic that may be used for similar infections if the bacteria are susceptible.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions with this medicine. However, if you are due for any vaccines, inform your doctor. Antibiotics do not affect vaccine efficacy, but the underlying infection may delay vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Shake well before use

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging with the prescription label. Bring a copy of your prescription in case of customs checks. Store it at room temperature and protect it from extreme heat or cold. If crossing time zones, adjust dosing times gradually to maintain even intervals. Keep it in your carry-on luggage to avoid loss or temperature extremes.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a respiratory tract infection
She was prescribed this medicine for bronchitis. She took it with food to avoid stomach upset and completed the 7-day course. Her cough and fever improved within 3 days, and she felt back to normal by the end of the course.
💡 Lesson: Taking the medicine with food and completing the full course led to a successful recovery.
👤 A 28-year-old man with chlamydia infection
He was prescribed this medicine for chlamydia. He experienced mild nausea initially but it subsided after taking it with meals. He completed the course and was cured. He also informed his partner, who got tested and treated.
💡 Lesson: Adherence to the full course and partner notification are crucial in treating sexually transmitted infections.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1-2 days, but it may take a few days for full effect. Complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.

Q: What if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe during pregnancy?

A: Erythromycin is generally considered safe during pregnancy (Category B), but you should consult your doctor before taking any medicine.

Q: Can I drink alcohol while taking this?

A: It is advisable to avoid alcohol as it may increase stomach upset and liver risk.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for e cin 250mg capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Erythromycin can cure viral infections like the common cold.
    Fact: Erythromycin is an antibiotic and is only effective against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking erythromycin as soon as you feel better.
    Fact: You must complete the full course as prescribed to prevent the infection from returning and to reduce antibiotic resistance.
  • Myth: Erythromycin is safe to take with any other medicine.
    Fact: Erythromycin interacts with many drugs, including warfarin, statins, and certain heart medications. Always inform your doctor about all medicines you take.

🔄 Alternative Options

Generic Alternatives

  • Erythromycin oral suspension
  • Erythromycin ethylsuccinate suspension
  • Erythromycin stearate suspension

Brand Alternatives

  • Althrocin Forte 250mg Syrup
  • Erythrocin 250mg Syrup
  • Erythromycin 250mg Syrup

📊 Comparison with Similar Medicines

[{"medicine":"Erythromycin","class":"Macrolide","spectrum":"Gram-positive, some Gram-negative, atypicals","common_uses":"Respiratory, skin, chlamydia"},{"medicine":"Azithromycin","class":"Macrolide","spectrum":"Broader Gram-negative coverage","common_uses":"Respiratory, STIs, otitis media"},{"medicine":"Clarithromycin","class":"Macrolide","spectrum":"Similar to erythromycin","common_uses":"Respiratory, H. pylori"},{"medicine":"Amoxicillin","class":"Penicillin","spectrum":"Gram-positive, some Gram-negative","common_uses":"Respiratory, urinary, skin"}]

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