dupox 40mg injection - Piroxicam (40mg) medicine

dupox 40mg injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Bennet Pharmaceuticals Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is dupox 40mg injection used for?

Alkem Piroxicam Injection (Piroxicam) is used to treat PAIN ANALGESICS. It contains Piroxicam (40mg), which Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthe. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Piroxicam
  • Manufacturer: Bennet Pharmaceuticals Limited
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š dupox 40mg injection Uses & Benefits

Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, musculoskeletal pain, dysmenorrhea.

Off-label uses: Acute pain, postoperative pain, fever.

๐Ÿ“‹ Drug Information

Generic Name(s)Piroxicam
Brand NameAlkem Piroxicam Injection
ManufacturerBennet Pharmaceuticals Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids)
Route of AdministrationIntramuscular injection.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular injection; peak plasma concentrations achieved within 1-2 hours.
DistributionWidely distributed throughout the body; crosses the placenta and enters breast milk.
Protein BindingApproximately 99% bound to plasma proteins, primarily albumin.
MetabolismExtensively metabolized in the liver via hydroxylation and glucuronidation; CYP2C9 is the primary enzyme involved.
Half-LifeApproximately 50 hours (range 30-86 hours).
ExcretionPrimarily renal excretion of metabolites; less than 5% excreted unchanged.
Bioavailability100% after intramuscular injection.
Onset of ActionWithin 30-60 minutes.
Peak Plasma Time1-2 hours.
Duration of ActionUp to 24 hours.

How It Works

Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis.

Mechanism Steps

1Piroxicam binds to COX-1 and COX-2 enzymes.
2Inhibits conversion of arachidonic acid to prostaglandin H2.
3Reduces synthesis of prostaglandins, prostacyclin, and thromboxanes.

๐Ÿ’ก How to Take dupox 40mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of dupox 40mg injection

โœ… Common Side Effects

  • Nausea
  • Dyspepsia
  • Abdominal pain
  • Diarrhea
  • Constipation
  • Headache
  • Dizziness

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hypertension
  • Heart failure
  • Thrombotic events

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Aplastic anemia
  • Agranulocytosis
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Major Increased risk of GI ulceration and bleeding
Lithium Major Increased lithium levels and toxicity
Methotrexate Major Increased methotrexate toxicity
Anticoagulants Major Enhanced anticoagulant effect
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
Corticosteroids Moderate Increased risk of GI ulceration
SSRIs Moderate Increased bleeding risk
Antacids Minor Possible reduced absorption of piroxicam
Digoxin Minor Possible increased digoxin levels
Phenytoin Minor Possible increased phenytoin levels

๐Ÿšจ Major Interactions

  • Warfarin
  • Aspirin
  • Lithium
  • Methotrexate
  • Anticoagulants

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Corticosteroids
  • SSRIs

โ„น๏ธ Minor Interactions

  • Antacids
  • Digoxin
  • Phenytoin

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; may be taken with food to reduce GI upset.

๐Ÿท Alcohol Interaction

Increased risk of gastrointestinal bleeding.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to piroxicam or NSAIDs, history of asthma, urticaria, or allergic-type reactions after aspirin/NSAIDs, active peptic ulcer disease, severe heart failure, severe renal impairment, perioperative pain in CABG surgery.

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, blood pressure, signs of GI bleeding, CBC.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; avoid use or discontinue breastfeeding.

๐Ÿ’Š Overdose Management

Symptomatic and supportive care; no specific antidote; consider activated charcoal if recent ingestion.

โฐ Missed Dose

If a dose is missed, take it as soon as remembered unless it is almost time for the next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for dupox 40mg injection

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Alternative brands with exact same active ingredient (Piroxicam (40mg)):

Medical Note: Always consult your doctor before switching medications.

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