Aquadol Spas 20mg/50mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain or cramping
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
- Rash or hives
- Irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is dp-spas tablet used for?
This medicine is a prescription-only intramuscular injection combining dicyclomine (an antispasmodic) and diclofenac (an NSAID) used for rapid relief of severe spasmodic pain such as renal colic, biliary colic, and severe menstrual cramps. It works by relaxing smooth muscles and reducing inflammation. It must be given by a healthcare professional and is not for self-injection.
- Generic Name: Dicyclomine + Diclofenac
- Manufacturer: Speciality Meditech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dp-spas tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डाइसाइक्लोमिन और डाइक्लोफेनाक का संयोजन है, जो इंजेक्शन के रूप में दी जाती है। इसका उपयोग गुर्दे की पथरी, पित्त की पथरी, गंभीर मासिक धर्म में ऐंठन, और मांसपेशियों के दर्द के कारण होने वाले तीव्र ऐंठन वाले दर्द के इलाज के लिए किया जाता है। यह दवा मांसपेशियों को आराम देकर और सूजन को कम करके दर्द से राहत देती है। यह केवल डॉक्टर या स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। इसे घर पर स्वयं न लगाएं।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, चक्कर आना, नींद आना, मुंह सूखना, धुंधली दृष्टि, और इंजेक्शन लगाने की जगह पर दर्द या लालिमा शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में गंभीर रक्तस्राव, गुर्दे की क्षति, एलर्जी प्रतिक्रिया, सीने में दर्द, और त्वचा पर गंभीर प्रतिक्रिया शामिल हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। स्वयं इंजेक्शन न लगाएं। अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों के बारे में बताएं, विशेष रूप से पेट के अल्सर, गुर्दे या यकृत की बीमारी, हृदय रोग, अस्थमा, या रक्तस्राव विकार। आप जो अन्य दवाएं ले रहे हैं, उनके बारे में भी बताएं। इस दवा के साथ शराब न लें। यदि आपको चक्कर आते हैं या नींद आती है तो वाहन न चलाएं। पर्याप्त पानी पिएं। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो डॉक्टर को बताएं।
💊 dp-spas tablet Uses & Benefits
[{"condition":"Renal colic","description":"Provides rapid relief of severe flank pain caused by kidney stones by relaxing ureteral smooth muscle and reducing inflammation.","evidence":"Well-established"},{"condition":"Biliary colic","description":"Relieves pain from gallbladder spasms by relaxing biliary smooth muscle and reducing prostaglandin-mediated inflammation.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Reduces pain and inflammation in acute muscle sprains, strains, and back pain when oral therapy is not feasible.","evidence":"Well-established"},{"condition":"Severe dysmenorrhea","description":"Eases severe menstrual cramps by reducing uterine contractions and prostaglandin production.","evidence":"Well-established"},{"condition":"Postoperative pain","description":"Used for short-term management of moderate to severe postoperative pain, especially when spasms are involved.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Acute pancreatitis pain","description":"Sometimes used for pain relief in acute pancreatitis, though evidence is limited and it is not a standard first-line treatment.","evidence":"Limited"},{"condition":"Irritable bowel syndrome with severe cramps","description":"May be used for short-term relief of severe abdominal cramps in IBS, but oral therapy is preferred.","evidence":"Limited"}]
Primary treatment for: Acute spasmodic pain (renal colic, biliary colic, dysmenorrhea, musculoskeletal pain)
Also treats: Kidney stones, Gallstones, Endometriosis, Irritable bowel syndrome, Postoperative pain
📋 Drug Information
| Generic Name(s) | Dicyclomine + Diclofenac |
| Brand Name | Aquadol Spas 20mg/50mg Injection |
| Manufacturer | Speciality Meditech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antispasmodic + NSAID |
| Route of Administration | Intramuscular injection. Administer deep into a large muscle such as the upper outer quadrant of the gluteus maximus or the vastus lateralis. Rotate injection sites. Do not inject intravenously or subcutaneously |
| Storage | Store in a cool, dry place at room temperature (15-30°C). Protect from light. Do not freeze. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Dicyclomine is a muscarinic receptor antagonist that blocks acetylcholine at postganglionic parasympathetic nerve endings, leading to relaxation of smooth muscle in the gastrointestinal, biliary, and urinary tracts. Diclofenac is a nonsteroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, thereby reducing the synthesis of prostaglandins, prostacyclin, and thromboxane. The combined effect provides both antispasmodic and anti-inflammatory pain relief.
Mechanism Steps
💡 How to Take dp-spas tablet
Strength: Each 2 mL ampoule contains Dicyclomine hydrochloride 20mg and Diclofenac sodium 50mg in an aqueous solution for intramuscular injection.
Dosage Information
| Adult Dosage | The usual adult dose is one intramuscular injection of this medicine (Dicyclomine 20mg + Diclofenac 50mg) given for short-term relief of acute spasmodic pain. It may be repeated after 6 to 8 hours if needed, but the total daily dose should not exceed 2 injections in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. Do not self-administer. This medicine is for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney injury, and cardiovascular events. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Diclofenac is contraindicated in severe kidney disease (eGFR <30 mL/min). Dose adjustment may be needed in moderate renal impairment. Consult a nephrologist or clinician for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Diclofenac is contraindicated in severe liver disease. Dose adjustment may be needed in mild to moderate hepatic impairment. Monitor liver function tests. |
| Maximum Daily Dose | The maximum recommended daily dose is 2 intramuscular injections (Dicyclomine 40mg + Diclofenac 100mg) in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dp-spas tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Ibuprofen | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| SSRIs | Moderate | |
| Corticosteroids | Moderate | |
| Cyclosporine | Moderate | |
| Anticholinergics | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., aspirin, ibuprofen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (ACE inhibitors, ARBs, diuretics)
- Selective serotonin reuptake inhibitors (SSRIs)
- Anticholinergics (e.g., antihistamines, tricyclic antidepressants)
- Cyclosporine
🍷 Alcohol Interaction
Avoid alcohol while receiving this medicine. Alcohol increases the risk of stomach bleeding, ulcers, and liver damage when combined with diclofenac. It may also worsen dizziness and drowsiness caused by dicyclomine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to dicyclomine, diclofenac, or other NSAIDs","Active peptic ulcer or history of recurrent ulcers","Severe kidney disease (eGFR
⚠️ Warnings & Precautions
["This medicine should only be administered by a healthcare professional.","Do not use for more than 3-5 days without medical review.","Use with caution in elderly patients due to increased risk of GI bleeding and kidney injury.","Avoid in patients with dehydration or hypovolemia.","May cause drowsiness or dizziness; avoid driving or operating machinery.","May cause urinary retention; use with caution in men with enlarged prostate.","May worsen glaucoma; use with caution.","Do not use concurrently with other NSAIDs.","Monitor for signs of bleeding, especially in patients on anticoagulants.","Inform your doctor if you have a history of heart disease, stroke, or blood clots."]
🤱 Lactation Safety
Diclofenac is excreted in breast milk in small amounts and is generally considered compatible with breastfeeding for short-term use. Dicyclomine may pass into breast milk and could cause anticholinergic effects in the infant; it is not recommended during breastfeeding. Consult your doctor before use.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, abdominal pain, drowsiness, confusion, seizures, and kidney failure. There is no specific antidote. Treatment is supportive and symptomatic. If overdose is suspected, seek immediate medical attention. Activated charcoal may be given if the patient presents early. Monitor vital signs, renal function, and electrolyte levels. Hemodialysis is not effective for removing diclofenac or dicyclomine.
⏰ Missed Dose
This medicine is usually given as a single dose or for a short duration. If you miss a scheduled dose, contact your healthcare provider for guidance. Do not attempt to self-administer an extra dose. If you miss a dose and are unsure what to do, skip the missed dose and continue with your next scheduled dose. Do not double the dose.
Additional Safety Advice
This medicine must be given only by a qualified healthcare professional. Do not attempt to self-inject. Inform your doctor about all your medical conditions, especially stomach ulcers, kidney or liver disease, heart problems, asthma, or bleeding disorders. Tell your doctor about all other medicines you take, including blood thinners, steroids, antidepressants, and blood pressure medicines. Avoid alcohol while receiving this medicine because it increases the risk of stomach bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy after the injection. Drink plenty of water unless your doctor advises otherwise. If you are pregnant, planning pregnancy, or breastfeeding, inform your doctor before receiving this medicine. Do not use this medicine for more than the recommended duration without medical advice.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney injury, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. Avoid concurrent use with other NSAIDs or anticoagulants. Consider alternative pain management strategies.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester, due to risks of premature closure of the ductus arteriosus and oligohydramnios. If you are planning pregnancy, consult your doctor to discuss safer alternatives for pain management. Do not use this medicine if you are trying to conceive without medical advice.
🏥 Post-Surgery Considerations
This medicine may be used for short-term postoperative pain management, but it should be avoided in patients undergoing coronary artery bypass graft (CABG) surgery due to increased cardiovascular risk. Inform your surgeon and anesthesiologist if you have received this medicine recently. It may increase bleeding risk during and after surgery.
🦷 Dental Procedures
Inform your dentist if you have recently received this medicine, as it may increase bleeding risk during dental procedures. Your dentist may recommend postponing elective dental work or taking precautions. Do not take this medicine for dental pain without consulting a doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting immediately after receiving this injection, especially if you feel dizzy or drowsy. Gentle stretching and low-impact activities like walking or swimming may be beneficial once pain subsides. Consult your doctor before resuming intense physical activity.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or blurred vision, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how the medicine affects you. It is advisable to rest for a few hours after the injection. Most people can resume normal activities the next day, but this depends on the underlying condition and individual response.
🛑 When to Stop This Medicine
This medicine is for short-term use only. Stop using it and consult your doctor if your pain does not improve within 3-5 days, if you experience severe side effects, or if you develop signs of bleeding, kidney problems, or allergic reactions. Do not stop any prescribed treatment without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of diclofenac can lead to gastrointestinal ulcers, bleeding, kidney damage, liver toxicity, and increased cardiovascular risk. Dicyclomine may cause chronic constipation, urinary retention, and dry mouth. If long-term pain management is needed, your doctor will consider safer alternatives and regular monitoring of kidney and liver function.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Oral forms of diclofenac and dicyclomine can be used once acute severe pain subsides.
Evidence: Well-establishedCan help manage chronic musculoskeletal pain and improve mobility.
Evidence: Well-establishedApplying heat pads can help relax muscles and relieve cramps.
Evidence: ModerateMay provide pain relief for some individuals with chronic pain.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor about this medicine. It is generally safe to receive vaccines while on this medicine, but consult your healthcare provider for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
This medicine is given by a healthcare professional and is not for self-administration. If you are traveling and may need this injection, carry a copy of your prescription and a letter from your doctor explaining the medical need. Store the injection in its original packaging at room temperature (15-30°C), away from direct sunlight. Do not freeze. If traveling by air, carry it in your hand luggage with proper documentation. Check customs regulations for carrying prescription injections. It is advisable to receive the injection at a medical facility rather than carrying it yourself.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This injection typically starts relieving pain within 15 to 30 minutes after administration.
A: The pain relief usually lasts for 4 to 6 hours, but this can vary from person to person.
A: No, this medicine must only be given by a qualified healthcare professional in a clinical setting.
A: Common side effects include nausea, dizziness, dry mouth, drowsiness, and injection site pain.
A: This medicine is generally avoided during pregnancy, especially in the third trimester. Consult your doctor.
A: No, alcohol should be avoided as it increases the risk of stomach bleeding and liver problems.
🤔 Common Patient Concerns
🔄 Substitutes for dp-spas tablet
View AllAlternative brands with exact same active ingredient:
-
diclospa 20 mg/50 mg tabletCipla Ltd ₹6.55 78.8% CHEAPER
-
bestogesic sps injectionBestoChem Formulations India Ltd ₹9.60 69% CHEAPER
-
dipospas 20mg/50mg tabletMerril Pharma Pvt Ltd ₹14.00 54.8% CHEAPER
-
dicyclo 20mg/50mg tabletSedate Healthcare Pvt Ltd ₹14.06 54.6% CHEAPER
-
antispas-k 20mg/50mg tabletTunic Healthcare ₹15.00 51.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This injection can be self-administered at home.
Fact: This medicine must only be given by a qualified healthcare professional in a clinical setting. - Myth: It is safe to use this injection daily for chronic pain.
Fact: This medicine is for short-term use only. Prolonged use increases the risk of serious side effects. - Myth: This injection is a painkiller that can be used for any type of pain.
Fact: It is specifically for spasmodic and inflammatory pain. It is not appropriate for all pain types. - Myth: It is safe to take this injection with other painkillers.
Fact: Combining with other NSAIDs increases the risk of bleeding and kidney damage. Always inform your doctor about all medicines you take.
🔄 Alternative Options
Generic Alternatives
- Dicyclomine + Diclofenac injection
Brand Alternatives
- Aquadol Spas 20mg/50mg Injection