Domperidone 5mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular heartbeat or palpitations
- Severe dizziness or fainting
- Muscle stiffness, tremors, or difficulty moving
- Swelling of face, lips, or throat
- Difficulty breathing
- Severe abdominal pain
- Blood in vomit or stool
If experiencing severe symptoms, call emergency services immediately.
What is domper 5mg tablet dt used for?
This medicine contains Domperidone 5mg, used to treat nausea, vomiting, and stomach emptying problems. It works by blocking dopamine receptors in the brain and gut. It is available by prescription only and should be taken before meals.
- Generic Name: Domperidone (5mg)
- Manufacturer: Ethicare Remedies
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 domper 5mg tablet dt के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन 5mg टैबलेट के रूप में उपलब्ध है और मुख्य रूप से उल्टी, जी मिचलाना और पेट से संबंधित समस्याओं जैसे गैस्ट्रोपेरेसिस और अपच के इलाज के लिए इस्तेमाल की जाती है। यह दवा पेट की गति को बढ़ाकर भोजन को पचाने में मदद करती है और मस्तिष्क में उल्टी के संकेतों को रोकती है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, सिरदर्द, पेट में ऐंठन और दस्त शामिल हैं। कुछ लोगों में स्तनों में दर्द या दूध का स्राव भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें अनियमित दिल की धड़कन, मांसपेशियों में अकड़न और एलर्जी की प्रतिक्रिया शामिल हो सकती है। अगर आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं के बारे में बताएं, खासकर दिल, लीवर या किडनी की बीमारी हो तो। इस दवा को शराब के साथ न लें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर की सलाह के बिना इसका इस्तेमाल न करें। दवा को डॉक्टर द्वारा बताई गई अवधि से ज्यादा न लें। इसे बच्चों की पहुंच से दूर रखें।
💊 domper 5mg tablet dt Uses & Benefits
[{"condition":"Nausea and vomiting","description":"This medicine is used to relieve nausea and vomiting from various causes, including gastrointestinal disorders, chemotherapy, and radiotherapy.","evidence":"Well-established"},{"condition":"Gastroparesis","description":"It helps improve gastric emptying in people with delayed stomach emptying, reducing symptoms like bloating, nausea, and early fullness.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"This medicine may be prescribed to relieve symptoms of functional dyspepsia, such as upper abdominal discomfort, bloating, and early satiety.","evidence":"Moderate"},{"condition":"Nausea and vomiting induced by dopamine agonists","description":"It is used to control nausea and vomiting caused by medicines like levodopa used in Parkinson's disease, but requires careful supervision.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Diabetic gastroparesis","description":"Sometimes prescribed off-label to improve gastric emptying in diabetic patients with gastroparesis, though evidence is limited.","evidence":"Limited"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"Occasionally used off-label to reduce reflux symptoms by accelerating gastric emptying, but not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Nausea and vomiting
Also treats: Gastroparesis, Functional dyspepsia, Gastroesophageal reflux disease
📋 Drug Information
| Generic Name(s) | Domperidone (5mg) |
| Brand Name | domper 5mg tablet dt |
| Manufacturer | Ethicare Remedies |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Dopamine (D2) receptor antagonist-Prokinetic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) located in the area postrema of the brain, which is outside the blood-brain barrier. By blocking these receptors, it prevents the signals that trigger nausea and vomiting. Additionally, this medicine acts on the gastrointestinal tract to enhance the coordinated contractions of the stomach and upper intestine, promoting gastric emptying and intestinal transit. This prokinetic effect is mediated through the same dopamine D2 receptor blockade in the gut, as dopamine normally inhibits gastrointestinal motility. The combination of central antiemetic and peripheral prokinetic actions makes this medicine effective for both nausea and vomiting and for symptoms of delayed gastric emptying.
Mechanism Steps
💡 How to Take domper 5mg tablet dt
Strength: Domperidone 5mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5mg to 10mg taken up to three times a day before meals, depending on the condition being treated. For nausea and vomiting, the dose may be 10mg up to three times daily. For gastroparesis, the dose may be 10mg up to four times daily. The maximum daily dose should not exceed 30mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially extrapyramidal reactions and cardiac effects. The dose should be individualized by a clinician, and the lowest effective dose should be used for the shortest duration. |
| Renal Impairment | In patients with severe renal impairment, the elimination half-life of this medicine may be prolonged. Dose reduction may be necessary. Consult a clinician for individualized dosing. |
| Hepatic Impairment | This medicine is contraindicated in patients with moderate to severe hepatic impairment. In mild hepatic impairment, use with caution and consider dose reduction. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | 30mg per day. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of domper 5mg tablet dt
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Erythromycin | Major | |
| Amiodarone | Major | |
| Haloperidol | Major | |
| Fluconazole | Moderate | |
| Verapamil | Moderate | |
| Clarithromycin | Moderate | |
| Antacids | Minor | |
| Opioid analgesics | Minor | |
| Alcohol | Moderate |
🚨 Major Interactions
- Ketoconazole
- Erythromycin
- Amiodarone
- Haloperidol
⚡ Moderate Interactions
- Fluconazole
- Verapamil
- Clarithromycin
🍷 Alcohol Interaction
Alcohol may increase the sedative effects of this medicine and can worsen dizziness or drowsiness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to domperidone or any component of the tablet","Prolactin-releasing pituitary tumour (prolactinoma)","Gastrointestinal obstruction, perforation, or bleeding","Moderate to severe hepatic impairment","Concomitant use with QT-prolonging drugs or potent CYP3A4 inhibitors","Known existing QT interval prolongation or cardiac conduction disorders"]
⚠️ Warnings & Precautions
["This medicine should be used with caution in patients with heart disease or electrolyte abnormalities.","Avoid use in patients with severe liver disease.","Use with caution in patients with kidney impairment; dose adjustment may be needed.","Do not use for longer than 7 days without medical advice.","Avoid concomitant use with drugs that prolong QT interval or inhibit CYP3A4.","Elderly patients may be more sensitive to the side effects, especially extrapyramidal reactions.","This medicine may cause drowsiness; avoid driving or operating machinery until you know how it affects you."]
🤱 Lactation Safety
This medicine passes into breast milk. It may cause side effects in the breastfed infant. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause symptoms such as drowsiness, confusion, extrapyramidal reactions, and QT prolongation. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and may include ECG monitoring and management of arrhythmias. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.
Additional Safety Advice
Before you start taking this medicine, inform your doctor about all your medical conditions, especially if you have heart problems, liver disease, kidney disease, or a history of breast cancer. Tell your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements, as this medicine can interact with many of them. Do not take this medicine for longer than your doctor has prescribed, as long-term use may increase the risk of side effects. Avoid drinking alcohol while taking this medicine, as it can worsen drowsiness and dizziness. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms. Keep this medicine out of the reach of children. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. Store this medicine at room temperature, away from moisture and direct sunlight. If you experience any signs of an allergic reaction, such as a rash, itching, swelling, or difficulty breathing, stop taking this medicine and seek emergency medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to the side effects of this medicine, particularly extrapyramidal reactions and cardiac arrhythmias. The dose should be individualized, and the lowest effective dose should be used for the shortest duration. Regular monitoring of heart rhythm and renal function is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to treat nausea and vomiting. However, it should be used with caution in patients recovering from surgery, especially those with heart conditions. Follow your surgeon's instructions regarding its use.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with certain medications used during dental procedures, and its effects on heart rhythm should be considered.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness or dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. If you experience palpitations or dizziness during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause dry mouth, which can be managed by sipping water. Generally, it does not significantly impact daily activities if taken as prescribed.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience serious side effects such as irregular heartbeat, muscle stiffness, or allergic reactions. Do not stop taking it abruptly without consulting your doctor, especially if you have been on long-term therapy.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of hyperprolactinemia, leading to breast tenderness, milk secretion, and menstrual irregularities. It may also increase the risk of cardiac arrhythmias, especially in elderly patients or those with heart disease. Regular monitoring of prolactin levels and cardiac function may be required. It is generally recommended to use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating small, frequent, low-fat meals can help manage nausea and gastroparesis symptoms.
Evidence: Well-establishedMay help reduce nausea and vomiting in some patients.
Evidence: LimitedNatural remedy that may help with nausea, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust your dosing schedule gradually, but consult your doctor for specific advice. Keep enough supply for your trip and check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after oral administration.
A: It can interact with several medicines, especially those affecting heart rhythm or liver enzymes. Always inform your doctor about all medicines you take.
A: Consult your doctor before using this medicine during pregnancy. It should be used only if clearly needed.
A: Serious side effects include irregular heartbeat, extrapyramidal reactions, and allergic reactions. Seek immediate medical help if these occur.
🤔 Common Patient Concerns
🔄 Substitutes for domper 5mg tablet dt
View AllAlternative brands with exact same active ingredient:
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emstal 5mg tabletMars Life Sciences Ltd ₹10.31 28.9% CHEAPER
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tridom 5mg tablet dtZydus Cadila ₹11.22 22.7% CHEAPER
-
dmp 5mg tabletGlorious Biotech ₹11.26 22.4% CHEAPER
-
domperon 5mg tabletCadila Pharmaceuticals Ltd ₹12.86 11.4% CHEAPER
-
dmp 5 tablet dtGlorious Biotech ₹14.06 3.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Domperidone is a painkiller.
Fact: Domperidone is not a painkiller; it is an antiemetic and prokinetic medicine used for nausea and stomach emptying problems. - Myth: Domperidone can be taken for any stomach upset.
Fact: Domperidone is specifically for nausea, vomiting, and delayed gastric emptying. It is not for general stomach pain or indigestion without these symptoms. - Myth: Domperidone is safe to take without a prescription.
Fact: Domperidone is a prescription medicine and should only be taken under medical supervision due to potential heart rhythm effects.
🔄 Alternative Options
Generic Alternatives
- Domperidone 5mg tablet
Brand Alternatives
- Domperon 5mg tablet