Acebey P 100 mg/650 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Persistent fever with sore throat
- Severe skin rash with blisters or peeling
If experiencing severe symptoms, call emergency services immediately.
What is doloral p 100 mg/650 mg tablet used for?
This medicine is a combination of Aceclofenac 100 mg and Paracetamol 650 mg used for short-term relief of pain and inflammation in conditions like osteoarthritis, dental pain, and musculoskeletal injuries. It works by reducing prostaglandins that cause pain and swelling. Take it with food to avoid stomach upset and do not exceed 3 tablets in 24 hours.
- Generic Name: Aceclofenac (100mg) + Paracetamol (650mg)
- Manufacturer: Biomiicron Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 doloral p 100 mg/650 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिफ्लोफेनाक 100 मिलीग्राम और पैरासिटामोल 650 मिलीग्राम का संयोजन है। इसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है, जैसे कि गठिया, दांत दर्द, मांसपेशियों में दर्द, और सर्जरी के बाद के दर्द में। यह दवा शरीर में प्रोस्टाग्लैंडिन नामक रसायन को कम करके दर्द और सूजन को कम करती है। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो। इसका सेवन डॉक्टर के परामर्श के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट या आंतों में रक्तस्राव, एलर्जी की प्रतिक्रिया, गुर्दे की समस्या, यकृत की क्षति और रक्त विकार शामिल हो सकते हैं। यदि आपको कोई गंभीर लक्षण दिखाई दे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को भोजन या दूध के साथ लें ताकि पेट में जलन न हो। निर्धारित मात्रा से अधिक न लें। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे यकृत को नुकसान और पेट में रक्तस्राव का खतरा बढ़ सकता है। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें। यदि आपको पेट के अल्सर, गुर्दे या यकृत की बीमारी, अस्थमा या रक्तस्राव विकार है तो अपने डॉक्टर को बताएं। 7 दिनों से अधिक इस दवा का उपयोग बिना डॉक्टर की सलाह के न करें।
💊 doloral p 100 mg/650 mg tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces pain and inflammation in rheumatoid arthritis as an adjunct to disease-modifying therapy.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps relieve pain and stiffness in ankylosing spondylitis.","evidence":"Moderate"},{"condition":"Acute musculoskeletal pain","description":"Used for short-term relief of acute musculoskeletal pain such as sprains, strains, and low back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from dental pain, including post-extraction pain.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of mild to moderate post-operative pain.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"Relieves pain associated with primary dysmenorrhea.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Fever","description":"Paracetamol component may reduce fever, but this combination is not primarily indicated for fever alone.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation
Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Acute musculoskeletal pain, Dental pain, Post-operative pain, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Aceclofenac (100mg) + Paracetamol (650mg) |
| Brand Name | doloral p 100 mg/650 mg tablet |
| Manufacturer | Biomiicron Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and modulating pain perception, and it also affects the hypothalamic heat-regulating center to reduce fever. Together, they provide effective analgesia and anti-inflammatory action.
Mechanism Steps
💡 How to Take doloral p 100 mg/650 mg tablet
Strength: Aceclofenac 100 mg + Paracetamol 650 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally two to three times a day, preferably after meals. The maximum daily dose should not exceed three tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate. Use for the shortest duration necessary. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose adjustment may be needed. Consult a doctor. Not recommended in severe kidney disease (eGFR <30 mL/min). |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose adjustment may be needed. Consult a doctor. Not recommended in severe liver disease. |
| Maximum Daily Dose | The maximum daily dose is 3 tablets (Aceclofenac 300 mg + Paracetamol 1950 mg) in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of doloral p 100 mg/650 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| SSRIs | Moderate | |
| Anticonvulsants | Moderate | |
| Probenecid | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
- ACE inhibitors and ARBs
- Diuretics
⚡ Moderate Interactions
- Antihypertensives (beta-blockers, calcium channel blockers)
- Antidepressants (SSRIs, SNRIs)
- Anticonvulsants (phenytoin, carbamazepine)
- Probenecid
- Cholestyramine
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage, especially due to the paracetamol component, and increases the risk of gastrointestinal bleeding due to the Aceclofenac component.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Aceclofenac, Paracetamol, or any other NSAIDs","Active peptic ulcer or history of recurrent peptic ulcer","Severe heart failure","Severe kidney disease (eGFR
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose.","Do not use for more than 7 days without medical advice.","Use with caution in elderly patients.","Use with caution in patients with kidney or liver disease.","Use with caution in patients with cardiovascular risk factors.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Do not drive or operate machinery if you feel dizzy or drowsy.","Keep out of reach of children."]
🤱 Lactation Safety
Aceclofenac and Paracetamol are excreted in breast milk. Paracetamol is generally considered safe during breastfeeding. Aceclofenac should be used with caution as its safety during lactation is not well established. Consult your doctor before use.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to paracetamol and gastrointestinal bleeding due to Aceclofenac. Symptoms of overdose include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine with food or milk to reduce stomach upset. Do not exceed the recommended dose. Avoid alcohol while taking this medicine as it increases the risk of liver damage and gastrointestinal bleeding. Do not take other pain relievers or NSAIDs without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, asthma, or bleeding disorders. Do not use this medicine for more than 7 days without medical advice. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. NSAIDs may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain relief as prescribed by your surgeon. Inform your surgeon about all medicines you are taking. Do not self-medicate after surgery.
🦷 Dental Procedures
This medicine can be used for dental pain relief, including after dental procedures. Inform your dentist if you are taking this medicine before any dental work. It may increase bleeding risk during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may increase pain while taking this medicine. Gentle stretching and low-impact exercises are recommended. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take rest if you feel unwell. Inform your employer if your work involves operating machinery.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach pain, black stools, vomiting blood, skin rash, or difficulty breathing. Do not stop taking it abruptly if you have been on long-term therapy without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney problems, liver damage, and cardiovascular events. Regular monitoring of liver and kidney function is advised. Use the lowest effective dose for the shortest duration. Consult your doctor regularly if long-term use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedApplying heat or cold packs can help reduce pain and inflammation.
Evidence: ModerateMay help relieve chronic pain in some individuals.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, if you have a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight and moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep enough supply for your trip and carry it in your hand luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.
A: You should inform your doctor about all other medicines you are taking, as this medicine can interact with several drugs including blood thinners, other NSAIDs, and certain antidepressants.
A: Consult your doctor before taking this medicine during pregnancy. It is generally avoided in the third trimester.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for doloral p 100 mg/650 mg tablet
View AllAlternative brands with exact same active ingredient:
-
stednac 650 100 mg/650 mg tabletStedman Pharmaceuticals Pvt Ltd ₹25.67 29.2% CHEAPER
-
unidic a 100 mg/650 mg tabletUnimarck Healthcare Ltd ₹27.19 25.1% CHEAPER
-
acebey p 100 mg/650 mg tabletAbbey Health Care Pvt Ltd ₹28.35 21.9% CHEAPER
-
cefen p 100mg/650mg tabletCE-Biotec Pvt Ltd ₹29.50 18.7% CHEAPER
-
beap 100 mg/650 mg tabletBiological E Ltd ₹31.78 12.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: This medicine should be taken with food to reduce the risk of stomach upset and ulcers. - Myth: This medicine is safe to take for any type of pain.
Fact: This medicine is indicated for specific types of pain and should only be used as prescribed by a doctor. - Myth: Taking more than the recommended dose will relieve pain faster.
Fact: Taking more than the recommended dose increases the risk of serious side effects and does not provide faster relief. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol should be avoided while taking this medicine as it increases the risk of liver damage and gastrointestinal bleeding.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 100 mg + Paracetamol 650 mg tablet
Brand Alternatives
- Acebey P 100 mg/650 mg tablet