Anadom 10mg/500mg Tablet: Complete Information
When to Call Your Doctor IMMEDIATELY
- Irregular heartbeat or palpitations
- Severe dizziness or fainting
- Yellowing of eyes or skin
- Severe abdominal pain
- Blood in vomit or stool
- Signs of allergic reaction such as rash, swelling of face or throat
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is dmp plus 10 mg/500 mg tablet used for?
This medicine is a combination of Domperidone and Paracetamol used to treat nausea, vomiting, and mild to moderate pain. It works by blocking nausea signals in the brain and reducing pain and fever. It is usually taken up to three times daily, but always follow your doctor's prescription.
- Generic Name: Domperidone + Paracetamol
- Manufacturer: Glorious Biotech
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dmp plus 10 mg/500 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन और पैरासिटामोल का संयोजन है, जिसका उपयोग मतली, उल्टी और हल्के से मध्यम दर्द के इलाज के लिए किया जाता है। यह माइग्रेन, अपच, और सर्जरी के बाद होने वाली मतली और दर्द में राहत देती है।
साइड इफेक्ट्स: सामान्य दुष्प्रभावों में मुँह सूखना, सिरदर्द, नींद आना और पेट में हल्की ऐंठन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन दिल की धड़कन अनियमित होना, स्तनों में दर्द या सूजन, और त्वचा पर गंभीर एलर्जी हो सकती है। अगर आपको सीने में धड़कन, बेहोशी, या त्वचा पर चकत्ते दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पैरासिटामोल की अधिक मात्रा लेने से लीवर को नुकसान हो सकता है, इसलिए निर्धारित मात्रा से अधिक न लें। शराब का सेवन न करें। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको हृदय, लीवर या गुर्दे की बीमारी है, तो डॉक्टर को बताएं। बिना सलाह के कुछ दिनों से अधिक इसका उपयोग न करें।
💊 dmp plus 10 mg/500 mg tablet Uses & Benefits
[{"condition":"Migraine with nausea","description":"Relieves headache pain and reduces nausea and vomiting associated with migraines.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Helps reduce bloating, early satiety, and upper abdominal discomfort by improving gastric emptying.","evidence":"Moderate"},{"condition":"Post-operative nausea and pain","description":"Used to manage nausea and mild to moderate pain after surgical procedures.","evidence":"Moderate"},{"condition":"Gastroparesis","description":"May improve symptoms of delayed gastric emptying, such as nausea and vomiting.","evidence":"Limited"}]
Off-label uses: [{"condition":"Nausea due to chemotherapy","description":"Sometimes used as an add-on antiemetic, but not first-line.","evidence":"Limited"},{"condition":"Premenstrual syndrome","description":"Occasionally prescribed for bloating and breast tenderness, but evidence is weak.","evidence":"Insufficient"}]
Primary treatment for: Migraine with nausea
Also treats: Functional dyspepsia, Post-operative nausea and pain, Gastroparesis
📋 Drug Information
| Generic Name(s) | Domperidone + Paracetamol |
| Brand Name | Anadom 10mg/500mg Tablet |
| Manufacturer | Glorious Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Antiemetic + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Domperidone is a peripheral dopamine D2 receptor antagonist that blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) and in the gastrointestinal tract. This action reduces nausea and vomiting and enhances gastric motility and emptying. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which elevates the pain threshold and lowers fever. The combination provides both antiemetic and analgesic effects.
Mechanism Steps
💡 How to Take dmp plus 10 mg/500 mg tablet
Strength: Each tablet contains Domperidone 10 mg and Paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken up to three times daily, depending on the condition being treated. The maximum daily dose should not exceed 3 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate; follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of domperidone, especially cardiac effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | In patients with severe renal impairment, the dosing frequency of domperidone may need to be reduced. Paracetamol does not require adjustment in renal impairment, but caution is advised. Consult a doctor for individualized dosing. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, dose reduction may be necessary. Avoid use in severe hepatic impairment. Paracetamol should be used with caution and at reduced doses in liver disease. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | Maximum daily dose: Domperidone 30 mg (3 tablets) and Paracetamol 1500 mg (3 tablets) in 24 hours. Do not exceed this limit. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dmp plus 10 mg/500 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Amiodarone | Major | |
| Warfarin | Moderate | |
| Alcohol | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Ketoconazole, itraconazole, clarithromycin
- Amiodarone, sotalol, quinidine
- Warfarin
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., dicyclomine)
- Opioid analgesics
- Alcohol
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage from paracetamol and may worsen drowsiness or dizziness caused by domperidone.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to domperidone or paracetamol","Gastrointestinal bleeding, mechanical obstruction, or perforation","Prolactin-releasing pituitary tumor (prolactinoma)","Severe liver impairment","Known QT interval prolongation or congenital long QT syndrome","Concomitant use with potent CYP3A4 inhibitors that prolong QT (e.g., ketoconazole, clarithromycin)"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose of paracetamol; high doses can cause liver failure.","Avoid alcohol while taking this medicine.","Use with caution in patients with heart disease, electrolyte abnormalities, or bradycardia.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Consult a doctor before use in pregnancy or breastfeeding.","Do not use for more than a few days without medical advice."]
🤱 Lactation Safety
Domperidone passes into breast milk and may increase milk production. It is sometimes used off-label to enhance lactation, but this should only be done under medical supervision. Paracetamol is considered safe during breastfeeding at recommended doses. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of paracetamol can cause severe liver damage. Symptoms may include nausea, vomiting, abdominal pain, and yellowing of skin or eyes. Seek immediate medical attention. The antidote is N-acetylcysteine, which is most effective when given within 8-10 hours of ingestion. Domperidone overdose may cause drowsiness, extrapyramidal symptoms, and QT prolongation. Treatment is supportive and symptomatic. Contact a poison control center or emergency department immediately.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose because higher doses of paracetamol can harm your liver. Avoid drinking alcohol while taking this medicine as it increases the risk of liver injury. Inform your doctor if you have heart problems, liver disease, kidney disease, or if you are pregnant or breastfeeding. Do not use this medicine for more than a few days without medical advice. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to the cardiac side effects of domperidone, such as QT prolongation. Use with caution and at the lowest effective dose. Regular monitoring of heart rhythm may be advised. Paracetamol should be used at reduced doses if liver function is impaired.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Domperidone is generally avoided during pregnancy unless clearly needed. Paracetamol is considered relatively safe but should be used at the lowest effective dose for the shortest duration.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to manage nausea and pain. However, it should only be used under medical supervision. Inform your surgeon and anesthesiologist about all medicines you are taking before surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with certain medications used during dental work, and its side effects like dry mouth may affect your comfort.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or drowsiness after taking this medicine, avoid strenuous exercise or activities that require alertness. Light exercise like walking may be beneficial for digestion, but consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause dry mouth, so keep water handy. Generally, it does not significantly impact daily activities if taken as prescribed.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within a few days, if they worsen, or if you experience any serious side effects such as irregular heartbeat, severe dizziness, or signs of liver problems. Do not stop abruptly without medical advice if you have been taking it regularly.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of domperidone may increase the risk of cardiac arrhythmias and elevated prolactin levels. Paracetamol, when used at recommended doses, is generally safe, but long-term high-dose use can affect liver function. Regular monitoring may be required.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating small, frequent meals and avoiding trigger foods can help manage nausea and dyspepsia.
Evidence: Well-establishedStress reduction may help reduce migraine frequency and digestive symptoms.
Evidence: ModerateMay help with nausea and pain in some individuals.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust your dosing schedule gradually under medical advice. Check local customs regulations regarding prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking it.
A: It can be taken with or without food, but taking it with food may reduce stomach upset.
A: Do not take additional paracetamol-containing products without consulting your doctor, as this can lead to overdose.
A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for dmp plus 10 mg/500 mg tablet
View AllAlternative brands with exact same active ingredient:
-
domin plus 10mg/500mg tabletMediwin Pharmaceuticals ₹15.00 51.5% CHEAPER
-
paradon 10mg/500mg tabletBestoChem Formulations India Ltd ₹16.41 46.9% CHEAPER
-
neuromol d 10mg/500mg tabletUltramark Healthcare Pvt Ltd ₹18.75 39.4% CHEAPER
-
acedome 10mg/500mg tabletSymbiosis Lab ₹20.63 33.3% CHEAPER
-
acemol d 10mg/500mg tabletBanson Pharmaceuticals Pvt Ltd ₹20.63 33.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of pain.
Fact: It is specifically for pain associated with nausea or gastrointestinal issues; it is not a general painkiller for all conditions. - Myth: It is safe to take with alcohol.
Fact: Alcohol increases the risk of liver damage from paracetamol and should be avoided. - Myth: It can be taken long-term without any risk.
Fact: Prolonged use should be under medical supervision due to potential side effects like QT prolongation and liver strain.
🔄 Alternative Options
Generic Alternatives
- Domperidone + Paracetamol combination generics
Brand Alternatives
- Domperidone + Paracetamol tablets from other manufacturers