Adom P 10mg/500mg Tablet: Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular heartbeat or palpitations
- Severe dizziness or fainting
- Muscle stiffness, tremors, or unusual movements
- Swelling of face, lips, or throat
- Difficulty breathing
- Yellowing of skin or eyes
- Severe abdominal pain
- Blood in vomit or stool
If experiencing severe symptoms, call emergency services immediately.
What is acedome 10mg/500mg tablet used for?
This medicine is a combination of Domperidone and Paracetamol used to treat nausea, vomiting, and associated pain. It works by improving stomach emptying and reducing pain and fever.
- Generic Name: Domperidone (10mg) + Paracetamol (500mg)
- Manufacturer: Symbiosis Lab
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acedome 10mg/500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन और पैरासिटामोल का संयोजन है, जिसका उपयोग मतली, उल्टी और उससे जुड़े दर्द के इलाज के लिए किया जाता है। यह पेट की खाली होने की गति को बढ़ाती है और दर्द तथा बुखार को कम करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, सिरदर्द, नींद आना और पेट में हल्की ऐंठन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इसमें अनियमित दिल की धड़कन, मांसपेशियों में अकड़न और एलर्जी प्रतिक्रिया हो सकती है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब का सेवन न करें क्योंकि इससे लीवर को नुकसान और नींद आने की समस्या बढ़ सकती है। यदि आपको दिल, लीवर या किडनी की समस्या है तो डॉक्टर को बताएं। गाड़ी चलाने या मशीन चलाने से बचें यदि आपको नींद आती है। बच्चों की पहुंच से दूर रखें।
💊 acedome 10mg/500mg tablet Uses & Benefits
[{"condition":"Nausea and vomiting","description":"This medicine helps relieve nausea and vomiting by blocking dopamine receptors in the brain and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"It reduces symptoms of bloating, early satiety, and upper abdominal discomfort by enhancing gastric motility.","evidence":"Moderate"},{"condition":"Gastroparesis","description":"Domperidone component improves gastric emptying in diabetic or idiopathic gastroparesis, while Paracetamol provides pain relief.","evidence":"Moderate"},{"condition":"Migraine-associated nausea","description":"Used to relieve nausea and pain during migraine attacks, though not a primary migraine treatment.","evidence":"Limited"}]
Off-label uses: [{"condition":"Prevention of chemotherapy-induced nausea","description":"Sometimes used as an add-on antiemetic, but not first-line.","evidence":"Limited"},{"condition":"Post-operative nausea and vomiting","description":"May be used off-label for short-term management, but other agents are preferred.","evidence":"Limited"}]
Primary treatment for: Nausea and vomiting with associated pain
Also treats: Functional dyspepsia, Gastroparesis, Migraine
📋 Drug Information
| Generic Name(s) | Domperidone (10mg) + Paracetamol (500mg) |
| Brand Name | acedome 10mg/500mg tablet |
| Manufacturer | Symbiosis Lab |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Domperidone is a peripheral dopamine D2 receptor antagonist that blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) and in the gastrointestinal tract. This action reduces nausea and vomiting and enhances gastric motility and emptying. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which reduces pain and fever. The combination provides both prokinetic and analgesic effects, making it useful for conditions where nausea and pain coexist.
Mechanism Steps
💡 How to Take acedome 10mg/500mg tablet
Strength: Tablet containing Domperidone 10 mg and Paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken up to three times daily, depending on the condition being treated. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Take with or without food as directed by your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use with caution and adjust dose as needed based on renal and hepatic function. Consult your doctor. |
| Renal Impairment | Dose adjustment may be required in patients with severe renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose of Paracetamol should not exceed 4000 mg (8 tablets of 500 mg) from all sources. Domperidone maximum daily dose is 30 mg (3 tablets of 10 mg). Do not exceed these limits. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acedome 10mg/500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Warfarin | Major | |
| Amiodarone | Major | |
| Atropine | Moderate | |
| Opioids | Moderate | |
| Alcohol | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Ketoconazole, Itraconazole, Clarithromycin
- Warfarin
- Amiodarone, Sotalol, Haloperidol
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., Atropine)
- Opioid analgesics
- Alcohol
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of liver damage from Paracetamol and may enhance drowsiness caused by Domperidone. It can also worsen gastrointestinal side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Domperidone or Paracetamol","Severe liver disease","Known QT prolongation or family history of long QT syndrome","Concomitant use with QT-prolonging drugs or potent CYP3A4 inhibitors","Gastrointestinal obstruction, perforation, or bleeding","Prolactin-releasing pituitary tumor (prolactinoma)"]
⚠️ Warnings & Precautions
["Use with caution in elderly patients due to increased risk of side effects.","Avoid in patients with severe renal impairment; dose adjustment may be needed.","Do not use for prolonged periods without medical supervision.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you have heart, liver, or kidney disease.","Do not exceed the recommended dose of Paracetamol to avoid liver damage."]
🤱 Lactation Safety
Domperidone is excreted in breast milk and may cause side effects in the infant. Paracetamol is considered safe during breastfeeding in usual doses. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to Paracetamol and cardiac arrhythmias due to Domperidone. Seek immediate medical attention. Treatment includes activated charcoal if within 1-2 hours, N-acetylcysteine for Paracetamol toxicity, and supportive care for cardiac effects. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Avoid alcohol while taking this medicine as it can increase the risk of liver damage and drowsiness. Inform your doctor if you have heart, liver, or kidney problems, or if you are taking other medications, especially blood thinners or antidepressants. Do not drive or operate heavy machinery if you feel drowsy. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for longer than your doctor recommends without a follow-up.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to side effects such as drowsiness, dry mouth, and cardiac arrhythmias. Use with caution and adjust dose based on renal and hepatic function. Regular monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination in pregnancy is not well established. Your doctor may recommend alternative treatments.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative nausea and vomiting, but only under medical supervision. It may interact with other medications used during surgery. Inform your surgeon and anesthesiologist about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with medications used during dental procedures. Your dentist may advise adjusting the dose or timing.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise immediately after taking this medicine if you feel drowsy or dizzy. Light activities like walking are generally safe. Consult your doctor before starting any exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause dry mouth, so keep water handy. Generally, it does not significantly impact desk work.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like irregular heartbeat, muscle stiffness, or allergic reactions, stop immediately and seek medical help. Your doctor will advise on the duration of treatment.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of Domperidone may increase the risk of cardiac arrhythmias and extrapyramidal symptoms. Long-term high-dose Paracetamol can cause liver damage. Regular monitoring of liver and kidney function may be required.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating small, frequent, bland meals can help reduce nausea and dyspepsia.
Evidence: Well-establishedGinger may help reduce nausea, but evidence is limited.
Evidence: LimitedMay help with nausea and vomiting, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, if you are unwell with nausea or vomiting, it may be advisable to postpone vaccination until you recover. Consult your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after oral administration.
A: It can be taken with or without food, but taking it with food may reduce stomach upset.
A: Consult your doctor before use. The safety profile in pregnancy is not well established for the combination.
🤔 Common Patient Concerns
🔄 Substitutes for acedome 10mg/500mg tablet
View AllAlternative brands with exact same active ingredient:
-
domin plus 10mg/500mg tabletMediwin Pharmaceuticals ₹15.00 27.3% CHEAPER
-
paradon 10mg/500mg tabletBestoChem Formulations India Ltd ₹16.41 20.5% CHEAPER
-
neuromol d 10mg/500mg tabletUltramark Healthcare Pvt Ltd ₹18.75 9.1% CHEAPER
-
acemol d 10mg/500mg tabletBanson Pharmaceuticals Pvt Ltd ₹20.63 SAME PRICE
-
Tremofen 10mg/500mg TabletSymbiosis Pharmaceuticals Pvt Ltd ₹20.63 SAME PRICE
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Adom P can be taken for any type of stomach pain.
Fact: It is specifically for nausea, vomiting, and associated pain, not for all stomach pains. - Myth: It is safe to take Adom P without a prescription.
Fact: It is a prescription medicine and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Domperidone + Paracetamol combination tablets from other manufacturers
Brand Alternatives
- Domperidone + Paracetamol tablets (various brands)