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diprobay lotion - Beclometasone (0.025% w/v) medicine

diprobay lotion - Uses, Price, Side Effects & Substitutes

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Beclometasone (0.025% w/v)
๐Ÿญ Leeford Healthcare Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is diprobay lotion used for?

Beclate 200 CFC Free Inhaler (Beclometasone) is used to treat DERMA. It contains Beclometasone (0.025% w/v), which Beclometasone is a corticosteroid that binds to glucocorticoid receptors, modula. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Beclometasone
  • Manufacturer: Leeford Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š diprobay lotion Uses & Benefits

Prophylactic management of bronchial asthma; allergic rhinitis (off-label).

Off-label uses: Allergic rhinitis, Nasal polyps, Chronic obstructive pulmonary disease (COPD)

๐Ÿ“‹ Drug Information

Generic Name(s)Beclometasone
Brand NameBeclate 200 CFC Free Inhaler
ManufacturerLeeford Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassGlucocorticoids
Route of AdministrationInhalation
StorageStore at room temperature (15-30ยฐC); protect from moisture and direct sunlight.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionInhaled beclometasone is absorbed rapidly from the lungs with some oral absorption from the swallowed portion.
DistributionDistributes widely in the body; crosses the placenta and enters breast milk.
Protein Binding87%
MetabolismMetabolized in the liver via CYP3A4 to active metabolite beclometasone-17-monopropionate (B17MP).
Half-Life2.8 hours (beclometasone); 2.7 hours (B17MP)
ExcretionPrimarily fecal (60%) and urinary (12%) as metabolites.
BioavailabilityApproximately 15-20% from inhaled dose; swallowed portion has low systemic bioavailability due to fi
Onset of ActionWithin 24-48 hours; maximal effect may take 1-2 weeks.
Peak Plasma Time0.5-1 hour after inhalation.
Duration of Action12-24 hours.

How It Works

Beclometasone is a corticosteroid that binds to glucocorticoid receptors, modulating gene expression to reduce inflammation.

Mechanism Steps

1Inhaled beclometasone reaches the lungs and binds to glucocorticoid receptors (GR) in airway epithelial cells and inflammatory cells.
2The drug-receptor complex translocates to the nucleus and binds to glucocorticoid response elements (GREs) on DNA.
3This binding modulates gene transcription: upregulates anti-inflammatory proteins (e.g., lipocortin-1) and downregulates pro-inflammatory cytokines (e.g., IL-1, IL-2, TNF-ฮฑ).

๐Ÿ’ก How to Take diprobay lotion

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of diprobay lotion

โœ… Common Side Effects

  • Hoarseness
  • Throat irritation
  • Cough
  • Oral candidiasis
  • Dysphonia

๐Ÿšจ Serious Side Effects

  • Adrenal suppression
  • Growth retardation in children
  • Glaucoma
  • Cataracts
  • Osteoporosis

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Angioedema
  • Bronchospasm
  • Psychiatric disturbances

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Major Increased systemic beclometasone exposure and risk of adrenal suppression.
Ritonavir Major Increased beclometasone levels; avoid co-administration.
Rifampin Major Decreased beclometasone efficacy due to increased metabolism.
Phenytoin Major Reduced beclometasone effect.
Diuretics Moderate Additive hypokalemia.
Cardiac glycosides Moderate Increased risk of arrhythmias if hypokalemia occurs.
Antidiabetic agents Minor May increase blood glucose levels.
NSAIDs Minor Increased risk of gastrointestinal bleeding.

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampin, phenytoin)

โšก Moderate Interactions

  • Diuretics (increased hypokalemia risk)
  • Cardiac glycosides (increased arrhythmia risk)

โ„น๏ธ Minor Interactions

  • Antidiabetic agents (may increase blood glucose)
  • NSAIDs (increased GI bleeding risk)

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No specific interaction; alcohol may worsen underlying condition.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to beclometasone or any excipient; status asthmaticus; untreated systemic infections.

๐Ÿ“Š Monitoring Parameters

Lung function tests (FEV1, PEFR); signs of adrenal suppression; growth in children; ocular pressure.

๐Ÿคฑ Lactation Safety

Caution; beclometasone is excreted in breast milk in small amounts.

๐Ÿ’Š Overdose Management

Acute overdose unlikely; chronic overdose may cause systemic corticosteroid effects; treat symptomatically.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for diprobay lotion

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Alternative brands with exact same active ingredient (Beclometasone (0.025% w/v)):

Medical Note: Always consult your doctor before switching medications.

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