dilzem cd 120 capsule er - Uses, Price, Side Effects & Substitutes
What is dilzem cd 120 capsule er used for?
Angizem CD 90 Capsule ER (Diltiazem) is used to treat CARDIAC. It contains Diltiazem (120mg), which Inhibits calcium influx into cardiac and vascular smooth muscle cells via L-type. Always consult your doctor before use. Take as prescribed.
- Generic Name: Diltiazem
- Manufacturer: Torrent Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ dilzem cd 120 capsule er Uses & Benefits
Hypertension, chronic stable angina, vasospastic angina, atrial fibrillation/flutter (rate control).
Off-label uses: Migraine prophylaxis, Raynaud's phenomenon, anal fissures (topical), hypertrophic cardiomyopathy.
๐ Drug Information
| Generic Name(s) | Diltiazem |
| Brand Name | Angizem CD 90 Capsule ER |
| Manufacturer | Torrent Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blockers- Nondihydropyridines |
| Route of Administration | Oral (extended-release capsule) |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits calcium influx into cardiac and vascular smooth muscle cells via L-type calcium channels, leading to vasodilation and decreased myocardial contractility.
Mechanism Steps
๐ก How to Take dilzem cd 120 capsule er
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of dilzem cd 120 capsule er
โ Common Side Effects
- Dizziness
- Headache
- Peripheral edema
- Bradycardia
- Constipation
- Nausea
- Flushing
๐จ Serious Side Effects
- Severe bradycardia
- Heart block
- Congestive heart failure
- Hepatotoxicity
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Gingival hyperplasia
- Gynecomastia
- Parkinsonism
- Photosensitivity
- Leukocytoclastic vasculitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Beta-blockers | Major | Increased risk of bradycardia, heart block, and hypotension. |
| Digoxin | Major | Increased digoxin levels; risk of toxicity. |
| Cyclosporine | Major | Increased cyclosporine levels; monitor levels. |
| Carbamazepine | Major | Increased carbamazepine levels; risk of toxicity. |
| Rifampin | Major | Decreased diltiazem efficacy. |
| Statins (simvastatin, lovastatin) | Major | Increased statin levels; risk of myopathy/rhabdomyolysis. |
| Cimetidine | Moderate | Increased diltiazem levels. |
| Phenytoin | Moderate | Increased phenytoin levels. |
| Midazolam | Moderate | Increased midazolam levels; prolonged sedation. |
| Theophylline | Moderate | Increased theophylline levels. |
| Lithium | Moderate | Increased lithium levels; risk of toxicity. |
| Grapefruit juice | Minor | Increased diltiazem levels. |
| Calcium supplements | Minor | May reduce antihypertensive effect. |
| NSAIDs | Minor | May reduce antihypertensive effect. |
๐จ Major Interactions
- Beta-blockers
- Digoxin
- Cyclosporine
- Carbamazepine
- Rifampin
- Statins (simvastatin, lovastatin)
โก Moderate Interactions
- Cimetidine
- Anticonvulsants (phenytoin)
- Benzodiazepines (midazolam)
- Theophylline
- Lithium
โน๏ธ Minor Interactions
- Grapefruit juice
- Calcium supplements
- NSAIDs
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase diltiazem levels; avoid high-fat meals with extended-release forms.
๐ท Alcohol Interaction
May enhance hypotensive effect; avoid excessive alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Sick sinus syndrome (without pacemaker), second- or third-degree AV block (without pacemaker), hypotension (systolic <90 mmHg), acute myocardial infarction with pulmonary congestion, hypersensitivity to diltiazem.
๐ Monitoring Parameters
Blood pressure, heart rate, ECG (PR interval), liver function tests, renal function.
๐คฑ Lactation Safety
Limited data; use with caution; appears in breast milk.
๐ Overdose Management
Activated charcoal, gastric lavage; supportive care: atropine for bradycardia, calcium gluconate, vasopressors for hypotension; temporary pacing for heart block.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for dilzem cd 120 capsule er
View AllAlternative brands with exact same active ingredient (Diltiazem (120mg)):
-
dz cd 120mg capsuleSunij Pharma Pvt Ltd โน22.36 92.8% CHEAPER
-
davaindia diltiazem 120mg tabletDavaindia Generic Pharmacy โน28.00 91% CHEAPER
-
line sr tabletDerma Prime โน45.00 85.5% CHEAPER
-
q-dil 120mg tabletAurobindo Pharma Ltd โน50.63 83.7% CHEAPER
-
ionozem cd 120mg tabletPfizer Ltd โน53.83 82.7% CHEAPER
-
iski 120mg tablet srStadmed Pvt Ltd โน55.34 82.2% CHEAPER
-
coriem 120mg tablet xlSun Pharmaceutical Industries Ltd โน60.50 80.6% CHEAPER
-
masdil bd 120mg tabletLupin Ltd โน64.42 79.3% CHEAPER
-
kaizem 120mg capsuleWockhardt Ltd โน70.55 77.3% CHEAPER
-
cardisec 120mg tabletTaj Pharma India Ltd โน111.70 64.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.