Diltiazem 120 mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fainting or severe dizziness
- Chest pain that is new or worsening
- Difficulty breathing or shortness of breath
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes (jaundice)
- Dark urine or severe abdominal pain
- Unusually slow or irregular heartbeat
- Severe headache with visual changes
If experiencing severe symptoms, call emergency services immediately.
What is line sr tablet used for?
Diltiazem 120 mg immediate-release tablet is a calcium channel blocker used to treat high blood pressure and chest pain (angina). It works by relaxing blood vessels and slowing the heart rate. It is taken orally, usually 3 to 4 times daily, and should be used exactly as prescribed.
- Generic Name: Diltiazem (120mg)
- Manufacturer: Derma Prime
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 line sr tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डिल्टियाज़ेम हाइड्रोक्लोराइड 120 मिलीग्राम की तत्काल रिलीज़ गोली है। यह कैल्शियम चैनल ब्लॉकर वर्ग की दवा है। इसका उपयोग उच्च रक्तचाप (हाइपरटेंशन), स्थिर एनजाइना (सीने में दर्द), और कुछ हृदय ताल विकारों जैसे एट्रियल फिब्रिलेशन के इलाज में किया जाता है। यह रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके काम करती है। इससे रक्तचाप कम होता है और हृदय पर दबाव कम पड़ता है।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, थकान, मतली और टखनों या पैरों में सूजन शामिल हैं। ये आमतौर पर हल्के होते हैं और शरीर के अनुकूल होने पर कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें धीमी हृदय गति, निम्न रक्तचाप, या यकृत की समस्या शामिल हो सकती है। यदि आपको बेहोशी, सीने में दर्द, सांस लेने में कठिनाई, या त्वचा या आंखों का पीलापन दिखे तो तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। गोली को चबाएं या तोड़ें नहीं। इस दवा के साथ अंगूर का रस न पिएं क्योंकि इससे दवा का स्तर बढ़ सकता है और दुष्प्रभाव हो सकते हैं। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं, विशेष रूप से बीटा-ब्लॉकर्स, डिगॉक्सिन, और कुछ एंटीअरिदमिक्स। इस दवा को अचानक बंद न करें। नियमित रूप से रक्तचाप, हृदय गति, और यकृत कार्य की निगरानी की आवश्यकता हो सकती है। यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं, या स्तनपान करा रही हैं, तो इस दवा का उपयोग करने से पहले अपने डॉक्टर से बात करें।
💊 line sr tablet Uses & Benefits
[{"condition":"Hypertension","description":"Lowers blood pressure by relaxing blood vessels and reducing heart rate, decreasing the risk of stroke and heart attack.","evidence":"Well-established"},{"condition":"Chronic stable angina","description":"Reduces the frequency and severity of chest pain by improving blood flow to the heart and reducing its workload.","evidence":"Well-established"},{"condition":"Atrial fibrillation or atrial flutter","description":"Helps control heart rate by slowing conduction through the AV node.","evidence":"Well-established"},{"condition":"Post-myocardial infarction protection","description":"May be used after a heart attack to reduce the risk of further cardiac events, especially when beta-blockers are not tolerated.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, though evidence is limited.","evidence":"Limited"},{"condition":"Raynaud's phenomenon","description":"May help reduce frequency and severity of vasospastic attacks in some patients.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Chronic stable angina, Atrial fibrillation, Atrial flutter
📋 Drug Information
| Generic Name(s) | Diltiazem (120mg) |
| Brand Name | line sr tablet |
| Manufacturer | Derma Prime |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blockers- Nondihydropyridines |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | Typically 2 years from the date of manufacture. Check the expiry date on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Diltiazem blocks L-type calcium channels in vascular smooth muscle and cardiac tissue. This inhibits the influx of calcium ions during membrane depolarization, leading to relaxation of blood vessels and reduced contractility of the heart. It also slows conduction through the AV node, which helps control heart rate in certain arrhythmias.
Mechanism Steps
💡 How to Take line sr tablet
Strength: Immediate-release tablet, 120 mg
Dosage Information
| Adult Dosage | The usual starting dose for hypertension is 30 mg to 120 mg taken 3 to 4 times daily, depending on the formulation. For angina, the dose may range from 30 mg to 120 mg taken 3 to 4 times daily. Your doctor will adjust the dose based on your response and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require lower initial doses due to increased sensitivity to the effects of diltiazem. Start with a low dose and titrate slowly. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dosage adjustment is provided in the manufacturer's labeling for renal impairment. However, use with caution and monitor renal function. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with hepatic impairment, diltiazem should be started at a lower dose and titrated slowly. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 480 mg for immediate-release formulations, but doses above 360 mg are not recommended in some guidelines. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of line sr tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Beta-blockers | Major | |
| Digoxin | Major | |
| CYP3A4 inhibitors | Major | |
| CYP3A4 inducers | Major | |
| Statins | Major | |
| Cyclosporine | Moderate | |
| Carbamazepine | Moderate | |
| Midazolam | Moderate | |
| Rifampin | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Beta-blockers (e.g., propranolol, metoprolol)
- Digoxin
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir)
- CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
- Statins (e.g., simvastatin, atorvastatin)
⚡ Moderate Interactions
- Cyclosporine
- Carbamazepine
- Midazolam
- Rifampin
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of diltiazem, leading to dizziness or fainting. It is advisable to limit or avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to diltiazem","Sick sinus syndrome (unless a pacemaker is present)","Second- or third-degree AV block (unless a pacemaker is present)","Severe hypotension (systolic BP
⚠️ Warnings & Precautions
["Use with caution in patients with impaired liver or kidney function.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not stop taking this medicine abruptly, as it may worsen angina or blood pressure.","Avoid grapefruit juice while taking this medicine.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Elderly patients may be more sensitive to the effects of this medicine.","Use with caution in patients with heart failure; monitor for worsening symptoms."]
🤱 Lactation Safety
Diltiazem is excreted in breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor, as it may cause side effects in the infant.
💊 Overdose Management
Overdose may cause severe hypotension, bradycardia, heart block, and cardiac arrest. Seek immediate medical attention. Treatment is supportive and may include intravenous fluids, vasopressors, and cardiac pacing. Activated charcoal may be used if ingestion is recent. Hemodialysis is not effective for removing diltiazem.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet unless your doctor advises otherwise. Avoid drinking grapefruit juice while taking this medicine, as it can increase the amount of medicine in your blood and cause side effects. Inform your doctor about all other medicines you are taking, especially beta-blockers, digoxin, and certain antiarrhythmics. Do not stop taking this medicine suddenly, as it can worsen your condition. Regular monitoring of blood pressure, heart rate, and liver function may be needed. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering and heart rate-slowing effects of this medicine. Start with a lower dose and monitor closely for dizziness, falls, and bradycardia.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally avoided during pregnancy unless clearly needed. Your doctor may switch you to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthesia and affect heart rate and blood pressure during surgery. Your doctor may adjust the dose before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may interact with certain local anesthetics or affect blood pressure during dental procedures. Your dentist may need to monitor your blood pressure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid strenuous activities until you know how this medicine affects you. If you experience dizziness, chest pain, or shortness of breath during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with dose adjustment.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your doctor decides to discontinue, they will provide a tapering schedule to avoid rebound effects.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. Regular check-ups for blood pressure, heart rate, and liver function are recommended. Some patients may develop tolerance or need dose adjustments over time. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can help manage hypertension and angina alongside medication.
Evidence: Well-establishedACE inhibitors, ARBs, beta-blockers, or diuretics may be alternatives based on your condition.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, inform your healthcare provider about this medicine before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting dosing times. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30-60 minutes after taking a dose, but it may take several days to weeks to achieve full blood pressure-lowering effects.
A: No, you should not stop taking this medicine without consulting your doctor. Stopping suddenly can cause rebound high blood pressure or worsening angina.
A: Avoid grapefruit juice and alcohol. Also, avoid driving or operating machinery until you know how this medicine affects you.
A: This medicine is generally avoided during pregnancy unless the benefit outweighs the risk. Consult your doctor if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for line sr tablet
View AllAlternative brands with exact same active ingredient:
-
dz cd 120mg capsuleSunij Pharma Pvt Ltd ₹22.36 50.3% CHEAPER
-
davaindia diltiazem 120mg tabletDavaindia Generic Pharmacy ₹28.00 37.8% CHEAPER
-
q-dil 120mg tabletAurobindo Pharma Ltd ₹50.63 12.5% COSTLIER
-
ionozem cd 120mg tabletPfizer Ltd ₹53.83 19.6% COSTLIER
-
iski 120mg tablet srStadmed Pvt Ltd ₹55.34 23% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Diltiazem can be stopped once blood pressure is normal.
Fact: Diltiazem controls blood pressure but does not cure hypertension. Stopping suddenly can cause rebound high blood pressure or angina. Always consult your doctor before stopping. - Myth: Diltiazem is safe to take with grapefruit juice.
Fact: Grapefruit juice can increase diltiazem levels and cause side effects. It is best to avoid grapefruit juice while taking this medicine. - Myth: Diltiazem is a beta-blocker.
Fact: Diltiazem is a calcium channel blocker, not a beta-blocker. They have different mechanisms of action, though both can slow the heart rate.
🔄 Alternative Options
Generic Alternatives
- Diltiazem hydrochloride
Brand Alternatives
- Dilzem
- Diltia
- Angizem