diapepsin p 170 mg/80 mg tablet - Pancreatin (170mg) + Dimethicone (80mg) medicine

diapepsin p 170 mg/80 mg tablet

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🏭 Union Drug 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

What is diapepsin p 170 mg/80 mg tablet used for?

This medicine contains Pancreatin (170mg) + Dimethicone (80mg) and is used to treat GASTRO INTESTINAL. Pancreatin replaces digestive enzymes; Dimethicone reduces surface tension of gas bubbles.. Always consult your doctor before use.

  • Generic Name: Pancreatin + Dimethicone
  • Manufacturer: Union Drug
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 diapepsin p 170 mg/80 mg tablet Uses & Benefits

Exocrine pancreatic insufficiency, dyspepsia, flatulence, bloating.

Off-label uses: Cystic fibrosis (pancreatic insufficiency)

📋 Drug Information

Generic Name(s)Pancreatin + Dimethicone
Brand NameDiapepsin P
ManufacturerUnion Drug
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassDigestive enzyme + Antiflatulent
Route of AdministrationOral
StorageStore at room temperature (15-30°C), protect from moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPancreatin acts locally in GI tract; Dimethicone is not absorbed systemically.
DistributionNot applicable as both act locally.
Protein BindingNot applicable.
MetabolismPancreatin is inactivated by gastric acid; Dimethicone is excreted unchanged.
Half-LifeNot applicable.
ExcretionPancreatin is excreted in feces; Dimethicone is excreted unchanged in feces.
BioavailabilityNot applicable (local action).
Onset of ActionPancreatin: 30-60 minutes; Dimethicone: immediate.
Peak Plasma TimeNot applicable.
Duration of ActionPancreatin: 2-4 hours; Dimethicone: variable.

How It Works

Pancreatin replaces digestive enzymes; Dimethicone reduces surface tension of gas bubbles.

Mechanism Steps

1Pancreatin replaces deficient pancreatic enzymes (lipase, amylase, protease) to aid digestion of fats, carbs, proteins.
2Dimethicone reduces surface tension of gas bubbles in GI tract, facilitating their expulsion.

💡 How to Take diapepsin p 170 mg/80 mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of diapepsin p 170 mg/80 mg tablet

✅ Common Side Effects

Nausea
Diarrhea
Abdominal cramps
Flatulence

🚨 Serious Side Effects

Allergic reactions
Hyperuricemia
Intestinal obstruction (rare)

⚠️ Rare Side Effects

Fibrosing colonopathy (high doses)
Perianal irritation

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Orlistat Major Reduced absorption of pancreatin
Acarbose Major Reduced efficacy of acarbose
Antacids Moderate Reduced pancreatin activity
Iron supplements Moderate Reduced iron absorption
Calcium supplements Minor Reduced calcium absorption

🚨 Major Interactions

  • Orlistat
  • Acarbose

⚡ Moderate Interactions

  • Antacids
  • Iron supplements

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to pancreatin or dimethicone, acute pancreatitis, acute flare of chronic pancreatitis.

🤱 Lactation Safety

Safe with caution

💊 Overdose Management

Supportive care; may cause hyperuricemia or diarrhea.

⏰ Missed Dose

Take as soon as remembered; skip if near next dose.

🔄 Substitutes for diapepsin p 170 mg/80 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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