dexit 0.5mg/10mg tablet - Uses, Price, Side Effects & Substitutes
What is dexit 0.5mg/10mg tablet used for?
Ambulax-FM Tablet (Flupenthixol + Melitracen) is used to treat NEURO CNS. It contains Flupenthixol (0.5mg) + Melitracen (10mg), which Flupenthixol blocks dopamine D1/D2 receptors; Melitracen inhibits serotonin and . Always consult your doctor before use. Take as prescribed.
- Generic Name: Flupenthixol + Melitracen
- Manufacturer: Daksh Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ dexit 0.5mg/10mg tablet Uses & Benefits
Depression with anxiety, psychotic disorders, mood disorders
Off-label uses: Chronic pain, insomnia, agitation in dementia
๐ Drug Information
| Generic Name(s) | Flupenthixol + Melitracen |
| Brand Name | Ambulax-FM Tablet |
| Manufacturer | Daksh Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Antipsychotic + Antidepressant |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Flupenthixol blocks dopamine D1/D2 receptors; Melitracen inhibits serotonin and norepinephrine reuptake
Mechanism Steps
๐ก How to Take dexit 0.5mg/10mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of dexit 0.5mg/10mg tablet
โ Common Side Effects
- Drowsiness
- Dry mouth
- Constipation
- Weight gain
- Extrapyramidal symptoms
๐จ Serious Side Effects
- Tardive dyskinesia
- Neuroleptic malignant syndrome
- QT prolongation
- Seizures
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Jaundice
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Hypertensive crisis, serotonin syndrome |
| Warfarin | Moderate | Increased anticoagulant effect |
| Alcohol | Major | Enhanced CNS depression |
๐จ Major Interactions
- MAOIs
- Linezolid
- Methylene Blue
- Other CNS depressants
- QT-prolonging drugs
โก Moderate Interactions
- Antihypertensives
- Anticholinergics
- Lithium
- SSRIs
- SNRIs
โน๏ธ Minor Interactions
- Cimetidine
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase levels
๐ท Alcohol Interaction
Avoid alcohol; increased CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, recent MI, severe CNS depression, narrow-angle glaucoma, concurrent MAOI use
๐ Monitoring Parameters
ECG, liver function, blood pressure, mental status, extrapyramidal symptoms
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Supportive care, ECG monitoring, activated charcoal, benzodiazepines for seizures
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double