atrodac-a capsule - Atorvastatin (10mg) + Aspirin (75mg) medicine

Atrodac-A Capsule - Uses, Price, Side Effects

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๐Ÿญ Daksh Pharma Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is atrodac-a capsule used for?

Atrodac-A Capsule is a combination of Atorvastatin (10mg) and Aspirin (75mg) used to reduce the risk of heart attack and stroke. Atorvastatin lowers bad cholesterol and triglycerides, while Aspirin prevents blood clots by inhibiting platelet aggregation. It is prescribed for patients with high cholesterol and cardiovascular disease.

  • Generic Name: Atorvastatin + Aspirin
  • Manufacturer: Daksh Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š atrodac-a capsule Uses & Benefits

Primary and secondary prevention of cardiovascular events in patients with hyperlipidemia and at risk of thrombotic events.

Off-label uses: Not applicable.

๐Ÿ“‹ Drug Information

Generic Name(s)Atorvastatin + Aspirin
Brand NameAztor Asp 75 Capsule
ManufacturerDaksh Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassHMG-CoA Reductase Inhibitor + Antiplatelet Agent
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAtorvastatin: Rapidly absorbed after oral administration; Aspirin: Rapidly and completely absorbed from the gastrointestinal tract.
DistributionAtorvastatin: High distribution into tissues; Aspirin: Widely distributed into body tissues and fluids.
Protein BindingAtorvastatin: 98% bound to plasma proteins; Aspirin: 80-90% bound to plasma proteins (mainly albumin
MetabolismAtorvastatin: Hepatic metabolism via CYP3A4; Aspirin: Hydrolyzed to salicylic acid in the liver and plasma.
Half-LifeAtorvastatin: 14 hours; Aspirin: 15-20 minutes (salicylic acid: 2-3 hours).
ExcretionAtorvastatin: Biliary excretion; Aspirin: Renal excretion of salicylic acid and metabolites.
BioavailabilityAtorvastatin: 14%; Aspirin: 50-75% (oral).
Onset of ActionAtorvastatin: 1-2 weeks for lipid-lowering effect; Aspirin: 30-60 minutes for antiplatelet effect.
Peak Plasma TimeAtorvastatin: 1-2 hours; Aspirin: 1-2 hours (salicylic acid).
Duration of ActionAtorvastatin: 24 hours; Aspirin: 7-10 days for platelet inhibition.

How It Works

Atorvastatin: Inhibits HMG-CoA reductase, reducing cholesterol synthesis; Aspirin: Irreversibly inhibits cyclooxygenase (COX-1), reducing thromboxane A2 production and platelet aggregation.

Mechanism Steps

1Atorvastatin competitively inhibits HMG-CoA reductase, reducing mevalonate and cholesterol synthesis.
2Decreased intracellular cholesterol leads to upregulation of LDL receptors, increasing LDL clearance.
3Aspirin irreversibly acetylates COX-1, blocking conversion of arachidonic acid to thromboxane A2.

๐Ÿ’ก How to Take atrodac-a capsule

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of atrodac-a capsule

โœ… Common Side Effects

  • Headache
  • Dizziness
  • Nausea
  • Diarrhea
  • Muscle pain
  • Dyspepsia
  • Increased liver enzymes

๐Ÿšจ Serious Side Effects

  • Rhabdomyolysis
  • Hepatotoxicity
  • Gastrointestinal bleeding
  • Hemorrhagic stroke
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Myopathy
  • Pancreatitis
  • Thrombocytopenia
  • Interstitial lung disease
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Clopidogrel Moderate Increased bleeding risk
Gemfibrozil Moderate Increased risk of myopathy
Erythromycin Moderate Increased statin levels
Antacids Minor Reduced aspirin absorption

๐Ÿšจ Major Interactions

  • Warfarin
  • Ciclosporin
  • Clarithromycin
  • Itraconazole
  • HIV protease inhibitors
  • Methotrexate

โšก Moderate Interactions

  • Digoxin
  • Oral contraceptives
  • Colchicine
  • Antacids
  • Fibrates
  • Niacin

โ„น๏ธ Minor Interactions

  • Grapefruit juice
  • Vitamin K antagonists (low dose)
  • Spironolactone

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice increases atorvastatin levels; avoid high-fat meals with aspirin.

๐Ÿท Alcohol Interaction

Increased risk of gastrointestinal bleeding with aspirin; alcohol may affect atorvastatin metabolism.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Active liver disease, unexplained persistent liver enzyme elevations, pregnancy, breastfeeding, active peptic ulcer, bleeding disorders, hypersensitivity to any component.

๐Ÿ“Š Monitoring Parameters

Liver function tests, lipid profile, renal function, signs of bleeding, INR if on warfarin.

๐Ÿคฑ Lactation Safety

Atorvastatin: Not recommended; Aspirin: Excreted in breast milk, avoid high doses.

๐Ÿ’Š Overdose Management

Symptomatic and supportive care; for aspirin overdose, consider gastric lavage, activated charcoal, and hemodialysis in severe cases.

โฐ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

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