dexgen 6mg tablet sr - Dexchlorpheniramine (6mg) medicine

Dexchlorpheniramine 6mg Tablet: Complete Medicine Guide

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🏭 Nexgen Rx Life Science Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for allergic conditions.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Irregular or rapid heartbeat
  • Seizures or convulsions
  • Severe drowsiness or confusion
  • Unusual bruising or bleeding
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is dexgen 6mg tablet sr used for?

Dexchlorpheniramine is a first-generation antihistamine used to treat allergic symptoms such as sneezing, runny nose, and itching. It works by blocking histamine and may cause drowsiness.

  • Generic Name: Dexchlorpheniramine (6mg)
  • Manufacturer: Nexgen Rx Life Science Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 dexgen 6mg tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी से होने वाले लक्षणों जैसे छींक आना, नाक बहना, आंखों में खुजली और त्वचा पर चकत्ते के इलाज में उपयोग की जाती है। यह शरीर में हिस्टामिन नामक पदार्थ को रोककर काम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना और थकान शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि आपको सांस लेने में कठिनाई, दिल की धड़कन अनियमित या दौरे पड़ें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेते समय शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। वाहन चलाने या मशीन चलाने से बचें जब तक आपको पता न चले कि यह दवा आप पर कैसे असर करती है। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 dexgen 6mg tablet sr Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Reduces itching and hives associated with allergic skin reactions.","evidence":"Well-established"},{"condition":"Pruritus","description":"Provides relief from itching due to various causes, including insect bites and contact dermatitis.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Insomnia","description":"Sometimes used off-label for its sedative effects to promote sleep, but this is not recommended due to potential side effects and lack of long-term safety data.","evidence":"Limited"},{"condition":"Motion sickness","description":"May be used off-label to prevent nausea and vomiting associated with motion sickness, though other agents are preferred.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Urticaria, Pruritus, Contact dermatitis

📋 Drug Information

Generic Name(s)Dexchlorpheniramine (6mg)
Brand Namedexgen 6mg tablet sr
ManufacturerNexgen Rx Life Science Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassH1 Antihistaminics (First Generation)
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid alcohol and other CNS depressants while taking this medicine.
3
Do not drive or operate machinery until you know how this medicine affects you.
4
Take the lowest effective dose for the shortest duration possible.
5
Consult your doctor if symptoms persist beyond 7 days or worsen.
6
Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
7
Keep out of reach of children and store in a cool, dry place.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Sneezing
This medicine is commonly prescribed for this.
Likely Use
✅
Runny nose
This medicine helps reduce nasal secretions.
Likely Use
✅
Itchy eyes
This medicine relieves allergic eye symptoms.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDexchlorpheniramine is well absorbed from the gastrointestinal tract after oral administration.
DistributionIt is widely distributed throughout the body, including the central nervous system.
Protein BindingApproximately 70-75% bound to plasma proteins.
MetabolismIt is metabolized in the liver, primarily by CYP2D6 and CYP3A4 enzymes.
Half-LifeThe elimination half-life is approximately 14 to 25 hours.
ExcretionIt is excreted mainly in the urine as metabolites and unchanged drug.
BioavailabilityNot established from the available information.
Onset of ActionOnset of action is typically within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentration is reached in about 2 to 3 hours.
Duration of ActionThe duration of action is approximately 4 to 6 hours, but sedative effects may last longer.

How It Works

Dexchlorpheniramine is a first-generation antihistamine that works by competitively blocking histamine H1 receptors in the gastrointestinal tract, blood vessels, and respiratory tract. By blocking these receptors, it prevents histamine from exerting its effects, which include vasodilation, increased vascular permeability, itching, and smooth muscle contraction. Additionally, it has anticholinergic properties that contribute to its side effects such as dry mouth and urinary retention.

Mechanism Steps

1
Histamine release: In allergic reactions, histamine is released from mast cells and basophils.
2
H1 receptor binding: Dexchlorpheniramine binds to H1 receptors on target cells, preventing histamine from binding.
3
Inhibition of allergic response: This blockade reduces symptoms such as sneezing, itching, and vasodilation.
4
Central nervous system effects: The drug crosses the blood-brain barrier and causes sedation by blocking histamine in the brain.

💡 How to Take dexgen 6mg tablet sr

Strength: Tablet, 6 mg

1Take this medicine by mouth with or without food.
2Swallow the tablet whole with a glass of water.
3Do not crush, chew, or break the tablet unless instructed by your doctor.
4Take it at the same time each day to maintain consistent levels.
5If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of dexchlorpheniramine is 2 mg to 4 mg every 4 to 6 hours as needed, not to exceed 12 mg in 24 hours. However, this medicine is a 6 mg tablet, so the dose may be 6 mg every 8 to 12 hours. The exact dose must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment may be necessary in patients with renal impairment. Consult a healthcare professional.
Hepatic ImpairmentDose adjustment may be necessary in patients with hepatic impairment. Consult a healthcare professional.
Maximum Daily Dose12 mg per day for adults, but individual dosing may vary. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of dexgen 6mg tablet sr

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Consult doctor if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid alcohol.
Fatigue (Common (5-10%))
Get adequate rest. Consult doctor if it interferes with daily activities.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling, severe dizziness, or difficulty breathing.
Irregular heartbeat (Rare (<0.1%))
Contact your doctor immediately if you feel palpitations or irregular pulse.
Seizures (Rare (<0.1%))
Seek emergency medical help if seizures occur.
Blood disorders (e.g., agranulocytosis, hemolytic anemia) (Rare (<0.1%))
Report unusual bruising, bleeding, or signs of infection to your doctor promptly.

⚠️ Rare Side Effects

Photosensitivity
Hepatotoxicity
Urinary retention
Blurred vision
Constipation

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Alcohol Major
Benzodiazepines Major
Opioids Major
Tricyclic antidepressants Moderate
Fluoxetine Moderate
Paroxetine Moderate
Atropine Moderate
Antihypertensives Minor
Corticosteroids Minor

🚨 Major Interactions

  • MAO inhibitors
  • Alcohol
  • Other CNS depressants (e.g., benzodiazepines, opioids, sleep aids)

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can significantly increase drowsiness and impair your ability to drive or operate machinery. It can also enhance central nervous system depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to dexchlorpheniramine or other antihistamines","Narrow-angle glaucoma","Urinary retention","Severe liver disease","MAO inhibitor therapy within 14 days","Newborns and premature infants"]

⚠️ Warnings & Precautions

["May impair ability to drive or operate machinery.","Avoid alcohol and other CNS depressants.","Use with caution in elderly patients due to increased risk of confusion and falls.","Use with caution in patients with asthma, increased intraocular pressure, hyperthyroidism, cardiovascular disease, or hypertension.","Do not exceed recommended dose.","Consult doctor if symptoms persist or worsen."]

🤱 Lactation Safety

Dexchlorpheniramine is excreted in breast milk and may cause drowsiness in the nursing infant. Consult your doctor before use.

💊 Overdose Management

Overdose may cause severe drowsiness, seizures, coma, respiratory depression, and anticholinergic effects. Seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Avoid alcohol and other central nervous system depressants while taking this medicine, as they can increase drowsiness. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not take this medicine for longer than prescribed without consulting your doctor. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more susceptible to the sedative and anticholinergic effects of this medicine, such as confusion, dry mouth, and urinary retention. Use with caution and lower doses may be required.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may interact with anesthetics and other medications used during surgery. Inform your surgeon and anesthesiologist that you are taking this medicine.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with local anesthetics or other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Identify and avoid allergens that trigger your symptoms.
🥗
Use air purifiers and keep windows closed during high pollen seasons.
😴
Maintain a healthy diet rich in fruits and vegetables.
💧
Stay hydrated to help reduce dry mouth.
🧘
Get adequate sleep to support your immune system.
🌞
Practice stress-reducing techniques like yoga or meditation.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness, which can affect your coordination. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds to reduce inflammation.
Avoid processed foods and excess sugar.
Stay well hydrated by drinking plenty of water.
Consume a balanced diet with plenty of fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job involves operating heavy machinery.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms improve, your doctor may adjust or discontinue the dose. Always follow your doctor's guidance.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance, meaning it may become less effective over time. It can also increase the risk of side effects such as drowsiness, dry mouth, and constipation. Regular monitoring by your doctor is recommended if you need to use it for an extended period.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Identifying and avoiding triggers can reduce the need for medication.

Evidence: Well-established
Nasal saline irrigation

Helps clear allergens from nasal passages and reduce symptoms.

Evidence: Well-established
Immunotherapy

Allergy shots or sublingual tablets can provide long-term relief for certain allergies.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust your dosing schedule gradually to avoid missed doses. Check local customs regulations regarding prescription medications before you travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She was prescribed this medicine for her sneezing and runny nose. She took it as directed and found relief within an hour, but experienced drowsiness. She adjusted her schedule to take it at bedtime, which helped her sleep and controlled her symptoms during the day.
💡 Lesson: Taking this medicine at bedtime can help manage drowsiness while still providing relief from allergy symptoms.
👤 A 50-year-old man with chronic hives
He started this medicine for itching and hives. He noticed significant improvement in itching within a few days. He was advised to avoid alcohol and to monitor for drowsiness. He found that taking it with food reduced stomach discomfort.
💡 Lesson: Consistent use and avoiding alcohol can improve tolerability and effectiveness of this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after taking it by mouth.

Q: How long do the effects last?

A: The effects typically last for 4 to 6 hours, but drowsiness may persist longer.

Q: Can I take this medicine if I have high blood pressure?

A: Consult your doctor before taking this medicine if you have high blood pressure, as it may interact with your medications or affect your condition.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for dexgen 6mg tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Dexchlorpheniramine is non-drowsy.
    Fact: Dexchlorpheniramine is a first-generation antihistamine and commonly causes drowsiness.
  • Myth: It can be used for long-term treatment of allergies without side effects.
    Fact: Long-term use may lead to tolerance and increased risk of side effects; consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Dexchlorpheniramine maleate tablets

Brand Alternatives

  • Polaramine
  • Dexchlor
  • Dexy
  • Histadyl

📊 Comparison with Similar Medicines

[{"medicine":"Dexchlorpheniramine","class":"First-generation antihistamine","sedation":"High","duration":"4-6 hours"},{"medicine":"Cetirizine","class":"Second-generation antihistamine","sedation":"Low","duration":"24 hours"},{"medicine":"Loratadine","class":"Second-generation antihistamine","sedation":"Low","duration":"24 hours"}]

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