Dexarab-l Capsule Sr: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or persistent vomiting
- Chest pain, palpitations, or difficulty breathing
- Sudden swelling of the face, lips, tongue, or throat
- Yellowing of the skin or eyes (jaundice)
- Uncontrollable muscle spasms, tremors, or stiffness
- High fever with muscle rigidity and confusion
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is dexarab-l capsule sr used for?
This medicine is a prescription combination of Dexrabeprazole 10 mg and Levosulpiride 75 mg used to treat acid reflux, heartburn, and functional dyspepsia. It works by reducing stomach acid and improving stomach emptying. It is usually taken once daily before breakfast. Do not take it without a doctor's advice.
- Generic Name: Dexrabeprazole (10mg) + Levosulpiride (75mg)
- Manufacturer: Zunison Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dexarab-l capsule sr के बारे में (Hindi Summary)
उपयोग: यह दवा डेक्सराबेप्राजोल और लेवोसल्पिराइड का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, हार्टबर्न, गैस्ट्रिक अल्सर और अपच के इलाज के लिए किया जाता है। यह पेट में एसिड का उत्पादन कम करती है और पेट खाली होने की प्रक्रिया को तेज करती है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मतली, दस्त, पेट दर्द, मुँह सूखना, नींद आना और चक्कर आना शामिल हैं। कुछ लोगों में स्तनों में सूजन, दूध का स्राव, मासिक धर्म में अनियमितता, या मांसपेशियों में अकड़न जैसे गंभीर दुष्प्रभाव भी हो सकते हैं। अगर आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर सुबह नाश्ते से पहले एक कैप्सूल। कैप्सूल को पानी के साथ पूरा निगलें, चबाएं या तोड़ें नहीं। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। अपने डॉक्टर से नियमित जांच कराते रहें।
💊 dexarab-l capsule sr Uses & Benefits
- [{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces acid reflux and heartburn by suppressing stomach acid production and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Helps relieve upper abdominal discomfort, bloating, and early fullness by enhancing stomach motility and reducing acid.","evidence":"Moderate"},{"condition":"Peptic ulcer disease","description":"Used as part of therapy to reduce acid and promote ulcer healing, often alongside antibiotics for H.
- pylori eradication.","evidence":"Well-established"},{"condition":"Gastritis","description":"Provides symptom relief by decreasing acid exposure to the inflamed stomach lining.","evidence":"Moderate"},{"condition":"Nausea and vomiting associated with delayed gastric emptying","description":"Levosulpiride component helps reduce nausea by improving stomach emptying.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Diabetic gastroparesis","description":"Sometimes prescribed to improve gastric emptying in people with diabetes, though evidence is limited.","evidence":"Limited"},{"condition":"Refractory nausea in palliative care","description":"Occasionally used off-label for nausea not responding to standard antiemetics.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Peptic ulcer disease, Gastritis, Diabetic gastroparesis
📋 Drug Information
| Generic Name(s) | Dexrabeprazole (10mg) + Levosulpiride (75mg) |
| Brand Name | dexarab-l capsule sr |
| Manufacturer | Zunison Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Dexrabeprazole is a proton pump inhibitor that irreversibly blocks the hydrogen-potassium ATPase enzyme in the stomach lining, reducing both basal and stimulated acid secretion. Levosulpiride is a substituted benzamide that selectively blocks dopamine D2 receptors in the chemoreceptor trigger zone and gastrointestinal tract, which enhances gastric motility and accelerates stomach emptying. The combined effect reduces acid exposure and improves symptoms of reflux and dyspepsia.
Mechanism Steps
💡 How to Take dexarab-l capsule sr
Strength: Capsule containing Dexrabeprazole 10 mg and Levosulpiride 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one capsule taken orally once daily before breakfast. However, the dose and duration of treatment must be individualized by a qualified clinician based on the specific indication, severity of symptoms, age, weight, renal function, and hepatic function. Do not self-adjust the dose. Follow your doctor's instructions exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and extrapyramidal symptoms. Dose adjustment may be necessary. Use with caution and monitor closely. |
| Renal Impairment | Levosulpiride is excreted by the kidneys. In patients with renal impairment, dose reduction may be required. This medicine is contraindicated in severe renal impairment (creatinine clearance less than 20 mL/min). Consult your doctor for dose adjustment. |
| Hepatic Impairment | Dexrabeprazole is metabolized in the liver. In patients with mild to moderate hepatic impairment, no dose adjustment is usually needed. In severe hepatic impairment, use with caution and monitor closely. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (dexrabeprazole 10 mg + levosulpiride 75 mg) per day. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dexarab-l capsule sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Clopidogrel | Major | |
| Warfarin | Moderate | |
| Levodopa | Major | |
| Ketoconazole | Major | |
| Methotrexate | Major | |
| Diazepam | Moderate | |
| Phenytoin | Moderate | |
| Antacids | Minor | |
| Sucralfate | Minor | |
| QT-prolonging drugs | Moderate |
🚨 Major Interactions
- Clopidogrel
- Methotrexate
- Ritonavir
- Ketoconazole, itraconazole
- Levodopa
⚡ Moderate Interactions
- Warfarin
- Diazepam
- Phenytoin
- Anticholinergic drugs
- QT-prolonging drugs
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase stomach acid production, worsen reflux symptoms, and add to the drowsiness and dizziness caused by levosulpiride. It may also increase the risk of liver-related side effects. If you drink alcohol, discuss safe limits with your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to dexrabeprazole, levosulpiride, or any component of the formulation","Epilepsy or a history of seizures","Pheochromocytoma","Breast cancer","Severe renal impairment (creatinine clearance less than 20 mL/min)","Concomitant use with levodopa","Pregnancy and breastfeeding (unless clearly needed and advised by a doctor)","Children and adolescents below 18 years of age"]
⚠️ Warnings & Precautions
["May cause drowsiness and dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of extrapyramidal symptoms and QT prolongation.","Long-term use may lead to vitamin B12 deficiency, hypomagnesemia, and increased risk of bone fractures.","May increase the risk of gastrointestinal infections such as Salmonella and Campylobacter.","Not recommended for patients with a history of QT interval prolongation or those taking QT-prolonging drugs.","Use with caution in patients with liver or kidney disease; dose adjustment may be required.","Do not use for immediate relief of heartburn; it is not an antacid.","Inform your doctor if you have a history of mental health conditions, as levosulpiride can affect mood.","Do not stop abruptly without consulting your doctor, as rebound acid hypersecretion may occur."]
🤱 Lactation Safety
Not established from the available information. It is not known whether dexrabeprazole or levosulpiride is excreted in human breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor.
💊 Overdose Management
Overdose of this medicine may cause severe drowsiness, dizziness, extrapyramidal symptoms, and cardiac arrhythmias. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if the overdose is recent. Monitor vital signs, ECG, and electrolytes. Contact a poison control center for guidance.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once daily before breakfast. Swallow the capsule whole with water; do not crush, chew, or open it. Do not take more than the prescribed dose, and do not stop suddenly without medical advice. Avoid alcohol while taking this medicine because it can worsen drowsiness and stomach irritation. Inform your doctor if you have kidney or liver problems, heart rhythm disorders, or a history of mental health conditions. Do not drive or operate heavy machinery until you know how this medicine affects you. Keep all follow-up appointments and report any new or worsening symptoms immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of side effects such as drowsiness, dizziness, extrapyramidal symptoms, and QT prolongation. Dose adjustment may be necessary. Regular monitoring of renal function, electrolytes, and cardiac status is advised. Falls prevention strategies should be discussed.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy unless clearly needed and advised by a doctor. If you are trying to conceive, discuss alternative treatments with your doctor. Use effective contraception while taking this medicine if you are of childbearing potential.
🏥 Post-Surgery Considerations
If you are undergoing surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped temporarily before surgery due to potential interactions with anesthetic agents and effects on gastric motility. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may affect bleeding risk if you are also on anticoagulants. Your dentist may recommend adjusting your medication schedule or taking precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, avoid vigorous exercise immediately after meals as it can worsen reflux. If you experience dizziness or drowsiness, avoid activities that require balance and coordination, such as cycling or using heavy gym equipment.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness and dizziness, which can affect your ability to drive or operate machinery. It is advisable to avoid these activities until you know how the medicine affects you. For most people, the sedative effect diminishes after a few days. If your job requires high alertness, discuss with your doctor about timing the dose or alternative options.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects such as movement disorders, irregular heartbeat, or allergic reactions, stop the medicine and seek immediate medical attention. Your doctor may taper the dose or switch to an alternative treatment based on your condition.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to vitamin B12 deficiency, hypomagnesemia, and an increased risk of bone fractures. It may also increase the risk of gastrointestinal infections. Levosulpiride can cause tardive dyskinesia and other extrapyramidal symptoms with prolonged use. Regular monitoring of blood levels, renal function, and symptoms is recommended. The lowest effective dose for the shortest duration should be used.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Dietary changes, weight loss, and elevating the head of the bed can significantly reduce reflux symptoms.
Evidence: Well-establishedPantoprazole, omeprazole, or esomeprazole may be used if dexrabeprazole is not suitable.
Evidence: Well-establishedRanitidine or famotidine may be alternatives for milder acid suppression.
Evidence: ModerateDomperidone or metoclopramide may be used if acid suppression is not the primary issue.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for any vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified on the label.
✅ DO
Keep in the original container with the lid tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, continue taking your dose at the same local time as usual, but consult your doctor if you are unsure. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling relief from heartburn and bloating within a few days, but the full effect on acid suppression may take up to 1 to 2 weeks of regular use.
A: It is best taken on an empty stomach, about 30 minutes before breakfast. If it causes stomach upset, consult your doctor.
A: If you remember within 12 hours, take it as soon as possible. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Do not stop without consulting your doctor. Stopping suddenly can cause rebound acid hypersecretion and worsening symptoms.
A: Long-term use should be monitored by your doctor due to potential risks such as vitamin B12 deficiency, low magnesium, and bone fractures. Regular follow-up is advised.
🤔 Common Patient Concerns
🔄 Substitutes for dexarab-l capsule sr
View AllAlternative brands with exact same active ingredient:
-
sulpraz 10mg/75mg capsuleAAR ESS Remedies Pvt Ltd ₹154.69 35.1% CHEAPER
-
evopride-dx 10mg/75mg tabletGlobus Labs ₹198.75 16.6% CHEAPER
-
dexelpride 10mg/75mg capsuleKindspirit Pharmaceutical ₹201.56 15.4% CHEAPER
-
levopraz 10mg/75mg capsuleDruto Laboratories ₹212.80 10.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for immediate relief of heartburn.
Fact: This medicine is not an antacid and does not provide instant relief. It works by reducing acid production over time and is meant for regular use as prescribed. - Myth: It is safe to take this medicine for as long as you want.
Fact: Long-term use should be monitored by a doctor due to potential risks such as vitamin B12 deficiency, hypomagnesemia, and bone fractures. - Myth: This medicine can be taken with alcohol without any problems.
Fact: Alcohol can worsen stomach irritation and increase drowsiness caused by this medicine. It is best to avoid alcohol. - Myth: If I feel better, I can stop the medicine immediately.
Fact: Stopping suddenly can cause rebound acid hypersecretion. Always consult your doctor before stopping.
🔄 Alternative Options
Generic Alternatives
- Dexrabeprazole + Levosulpiride combination capsules from other manufacturers
Brand Alternatives
- Dexarab-L Capsule SR
- Dexrab-L Capsule SR
- Levosulpiride + Dexrabeprazole Capsule SR