Aram 100mg/500mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is delide p 100mg/500mg tablet used for?
This medicine is a combination of nimesulide and paracetamol used for short-term relief of acute pain and inflammation. It works by reducing prostaglandins that cause pain and swelling. It should be taken with food and not for more than 15 days without medical advice.
- Generic Name: Nimesulide (100mg) + Paracetamol (500mg)
- Manufacturer: Optima Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 delide p 100mg/500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नाइमेसुलाइड और पैरासिटामोल का संयोजन है, जिसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है। यह मुख्य रूप से जोड़ों के दर्द, मांसपेशियों के दर्द, दांतों के दर्द, मासिक धर्म के दर्द और सर्जरी के बाद के दर्द के लिए दी जाती है। यह दवा सूजन पैदा करने वाले प्रोस्टाग्लैंडिन को कम करके काम करती है। इसे भोजन के साथ लेना चाहिए और 15 दिनों से अधिक समय तक बिना डॉक्टर की सलाह के नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त और चक्कर आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत की क्षति और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला या खूनी मल, खून की उल्टी, गंभीर पेट दर्द, आंखों या त्वचा का पीलापन, या पेशाब में कमी महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक या अवधि से अधिक न लें। इसे हमेशा भोजन या दूध के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे यकृत और पेट की समस्याओं का खतरा बढ़ सकता है। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो इस दवा का उपयोग करने से पहले डॉक्टर से सलाह लें।
💊 delide p 100mg/500mg tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Reduces joint pain and stiffness, improving mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps manage pain and swelling in rheumatoid arthritis as an adjunct to disease-modifying therapy.","evidence":"Moderate"},{"condition":"Dental pain","description":"Provides relief from acute dental pain, including post-extraction pain.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of mild to moderate post-surgical pain.","evidence":"Moderate"},{"condition":"Primary dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Fever","description":"May be used off-label for fever reduction, though paracetamol alone is preferred.","evidence":"Limited"}]
Primary treatment for: Acute pain and inflammation
Also treats: Osteoarthritis, Rheumatoid arthritis, Dental pain, Post-operative pain, Primary dysmenorrhea
📋 Drug Information
| Generic Name(s) | Nimesulide (100mg) + Paracetamol (500mg) |
| Brand Name | delide p 100mg/500mg tablet |
| Manufacturer | Optima Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Nimesulide is a selective inhibitor of the cyclooxygenase-2 (COX-2) enzyme, which reduces the synthesis of prostaglandins, thereby decreasing inflammation, pain, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and modulating pain perception, and it also has antipyretic effects. Together, they provide enhanced analgesic and anti-inflammatory effects.
Mechanism Steps
💡 How to Take delide p 100mg/500mg tablet
Strength: Each tablet contains nimesulide 100 mg and paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally twice daily, preferably after meals. The maximum recommended duration of treatment is 15 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine is not recommended for children below 12 years of age. Consult a pediatrician for appropriate pain relief options. |
| Elderly Dosage | Elderly patients (above 65 years) may be more susceptible to the side effects of this medicine, especially gastrointestinal bleeding, kidney impairment, and liver toxicity. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing. Avoid in severe kidney impairment. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose reduction may be necessary. Avoid in severe liver impairment. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet twice daily (nimesulide 200 mg + paracetamol 1000 mg). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of delide p 100mg/500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Antihypertensives | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, diclofenac)
- ACE inhibitors and ARBs
- Diuretics
- Lithium
- Methotrexate
⚡ Moderate Interactions
- Corticosteroids
- SSRIs
- Antihypertensives
- Alcohol
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage, especially with paracetamol, and can worsen gastrointestinal irritation and bleeding caused by nimesulide.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to nimesulide, paracetamol, or any component of the formulation","History of gastrointestinal bleeding or perforation related to NSAID use","Active or history of peptic ulcer disease","Severe liver impairment","Severe kidney impairment","Severe heart failure","Children below 12 years of age","Third trimester of pregnancy","Breastfeeding"]
⚠️ Warnings & Precautions
["Use the lowest effective dose for the shortest duration possible.","Avoid concurrent use with other NSAIDs or paracetamol-containing products.","Take with food or milk to reduce gastrointestinal irritation.","Avoid alcohol during treatment.","Use with caution in elderly patients and those with kidney or liver disease.","Monitor for signs of gastrointestinal bleeding, liver toxicity, and kidney impairment.","Do not use for more than 15 days without medical supervision."]
🤱 Lactation Safety
Nimesulide and paracetamol are excreted in breast milk. This medicine is not recommended during breastfeeding due to potential risks to the infant. Consult your doctor for alternative pain relief options.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage, kidney failure, and gastrointestinal bleeding. Seek immediate medical attention. Treatment includes activated charcoal if within 1-2 hours of ingestion, N-acetylcysteine for paracetamol toxicity, and supportive care. Monitor liver and kidney function closely.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Always take it with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine as it can increase the risk of liver damage and gastrointestinal bleeding. Do not take other pain relievers or NSAIDs concurrently without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, high blood pressure, or heart failure. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and liver toxicity from this medicine. Use with caution, at the lowest effective dose, and for the shortest duration. Regular monitoring of kidney and liver function is recommended.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester, due to the risk of premature closure of the ductus arteriosus and other complications. If you are planning pregnancy, consult your doctor for safer pain relief options.
🏥 Post-Surgery Considerations
This medicine may be used for short-term post-operative pain management. However, it should be used with caution after surgery, especially if you have kidney or liver issues or are taking other medications. Follow your surgeon's instructions.
🦷 Dental Procedures
This medicine can be used for short-term relief of dental pain, including after dental extractions. Inform your dentist if you are taking this medicine before any dental procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid strenuous exercise or activities that could cause injury, as it may mask pain and lead to overexertion. Listen to your body and rest if you feel pain.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take regular breaks if you have pain.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your pain does not improve within 7 days, if it worsens, or if you experience any serious side effects such as stomach pain, black stools, or yellowing of the eyes. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver damage, and cardiovascular events. It should only be used for short-term relief. Regular monitoring of liver and kidney function is advised if prolonged use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedApplying heat or cold packs can help reduce pain and inflammation.
Evidence: ModerateMay provide pain relief for some individuals.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight and moisture. If crossing time zones, adjust dosing times gradually to maintain consistent intervals. Check local customs regulations regarding prescription medicines before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.
A: It is best taken with food or milk to reduce the risk of stomach upset.
A: It can interact with several medicines, including blood thinners and blood pressure medicines. Always inform your doctor about all medicines you are taking.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for delide p 100mg/500mg tablet
View AllAlternative brands with exact same active ingredient:
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Theraflam 100mg/500mg TabletParex Pharmaceuticals Pvt Ltd ₹2.50 89.7% CHEAPER
-
nulid plus 100mg/500mg tabletGeneral Pharmaceuticals Pvt Ltd ₹3.28 86.5% CHEAPER
-
alnim p 100 mg/500 mg tabletAlliaance Biotech ₹3.86 84.2% CHEAPER
-
nes forte tabletPCI Pharmaceuticals ₹4.22 82.7% CHEAPER
-
doliprane n 100 mg/500 mg tabletAbbott ₹4.45 81.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for long-term use.
Fact: This medicine is only for short-term use. Prolonged use can cause liver, kidney, and gastrointestinal problems. - Myth: It can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach irritation. - Myth: It is safe to take with other pain relievers.
Fact: Combining with other NSAIDs or paracetamol can increase the risk of side effects.
🔄 Alternative Options
Generic Alternatives
- Nimesulide 100 mg + Paracetamol 500 mg tablet