defcort 24 tablet - Deflazacort (24mg) medicine

defcort 24 tablet

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🏭 Macleods Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
🤰 Pregnancy Category C 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

What is defcort 24 tablet used for?

This medicine contains Deflazacort (24mg) and is used to treat HORMONES. Binds to glucocorticoid receptor, modulating gene expression and suppressing inflammation.. Always consult your doctor before use.

  • Generic Name: Deflazacort
  • Manufacturer: Macleods Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 defcort 24 tablet Uses & Benefits

Inflammatory conditions, autoimmune disorders, allergic reactions, Duchenne muscular dystrophy.

Off-label uses: COVID-19 (severe), acute respiratory distress syndrome.

📋 Drug Information

Generic Name(s)Deflazacort
Brand NameAnort 30 Tablet
ManufacturerMacleods Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassHORMONES
Action ClassGlucocorticoids
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed orally; peak plasma concentration reached in 1-2 hours.
DistributionWidely distributed; crosses placenta; enters breast milk.
Protein BindingApproximately 40% bound to plasma proteins.
MetabolismHepatic metabolism via CYP3A4 to active metabolite 21-desacetyl deflazacort.
Half-Life1.1-2.0 hours (parent); 2-4 hours (active metabolite).
ExcretionRenal excretion of metabolites; less than 5% unchanged.
Bioavailability70% (oral).
Onset of ActionWithin 1-2 hours.
Peak Plasma Time1-2 hours.
Duration of Action12-36 hours.

How It Works

Binds to glucocorticoid receptor, modulating gene expression and suppressing inflammation.

Mechanism Steps

1Binds to glucocorticoid receptor in cytoplasm
2Receptor-ligand complex translocates to nucleus
3Binds to glucocorticoid response elements on DNA
4Modulates transcription of anti-inflammatory and immunosuppressive genes
5Inhibits phospholipase A2, reduces prostaglandins and leukotrienes
6Suppresses cytokine production (IL-1, IL-2, TNF-alpha)

💡 How to Take defcort 24 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of defcort 24 tablet

✅ Common Side Effects

Increased appetite
Weight gain
Insomnia
Mood changes
GI upset

🚨 Serious Side Effects

Adrenal suppression
Osteoporosis
Glaucoma
Cataracts
Pancreatitis

⚠️ Rare Side Effects

Avascular necrosis
Pseudotumor cerebri
Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major Increased deflazacort levels
Rifampin Major Decreased deflazacort efficacy
Warfarin Major Altered anticoagulant effect
NSAIDs Major Increased GI bleeding risk
Oral hypoglycemics Moderate Reduced hypoglycemic effect
Insulin Moderate Reduced hypoglycemic effect
Diuretics Moderate Increased potassium loss
Live vaccines Moderate Risk of disseminated infection
Antacids Minor Slightly reduced absorption
Oral contraceptives Minor Increased corticosteroid levels

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP3A4 inducers (e.g., rifampin)
  • Anticoagulants (e.g., warfarin)
  • NSAIDs (e.g., aspirin)

⚡ Moderate Interactions

  • Oral hypoglycemics
  • Insulin
  • Diuretics
  • Vaccines (live attenuated)

🍷 Alcohol Interaction

May increase risk of gastrointestinal bleeding.

🛡️ Safety & Warnings

🚫 Contraindications

Systemic fungal infections, hypersensitivity to deflazacort, live virus vaccination.

🤱 Lactation Safety

Caution; excreted in breast milk.

💊 Overdose Management

Supportive care; no specific antidote; monitor electrolytes and glucose.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose.

🔄 Substitutes for defcort 24 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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