davaindia nicorandil 5mg tablet

4.6 (17 reviews)

Nicorandil (5mg)

🏭 Davaindia Generic Pharmacy 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is davaindia nicorandil 5mg tablet used for?

Alcoran (Nicorandil) is used to treat CARDIAC. It contains Nicorandil (5mg), which Nicorandil is a potassium channel activator and a nitrate-like vasodilator. It o. Always consult your doctor before use. Take as prescribed.

Generic Name: Nicorandil
Manufacturer: Davaindia Generic Pharmacy
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 davaindia nicorandil 5mg tablet Uses & Benefits

Prophylaxis and long-term treatment of angina pectoris.

Off-label uses: Raynaud's phenomenon, heart failure (limited evidence).

📋 Drug Information

Generic Name(s)	Nicorandil
Brand Name	Alcoran
Manufacturer	Davaindia Generic Pharmacy
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	Potassium channel opener
Route of Administration	Oral.
Storage	Store at room temperature (20-25°C), protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed after oral administration.

DistributionWidely distributed; volume of distribution approximately 1.4 L/kg.

Protein BindingApproximately 25% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via denitration and glucuronidation.

Half-LifeApproximately 1 hour (parent drug); active metabolites have longer half-life.

ExcretionRenal excretion of metabolites; less than 1% excreted unchanged.

BioavailabilityApproximately 75-80% due to first-pass metabolism.

Onset of ActionWithin 30 minutes.

Peak Plasma Time0.5-1 hour.

Duration of ActionUp to 12 hours.

How It Works

Nicorandil is a potassium channel activator and a nitrate-like vasodilator. It opens ATP-sensitive potassium channels in vascular smooth muscle, leading to hyperpolarization and relaxation, and also acts as a nitric oxide donor, increasing cGMP.

Mechanism Steps

1Binds to ATP-sensitive potassium channels on vascular smooth muscle cells.

2Opens K_ATP channels, causing potassium efflux and membrane hyperpolarization.

3Hyperpolarization closes voltage-gated calcium channels, reducing calcium influx.

💡 How to Take davaindia nicorandil 5mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of davaindia nicorandil 5mg tablet

✅ Common Side Effects

Headache
Flushing
Dizziness
Nausea
Vomiting

🚨 Serious Side Effects

Hypotension
Reflex tachycardia
Angioedema
Hepatic dysfunction

⚠️ Rare Side Effects

Oral ulceration
Gastrointestinal bleeding
Myocardial ischemia (paradoxical)

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Sildenafil	Major	Severe hypotension
Riociguat	Major	Severe hypotension
Alcohol	Moderate	Additive vasodilation and hypotension

🚨 Major Interactions

Phosphodiesterase-5 inhibitors (e.g., sildenafil)
Soluble guanylate cyclase stimulators (e.g., riociguat)

⚡ Moderate Interactions

Antihypertensives
Alcohol
Nitrates

ℹ️ Minor Interactions

CYP3A4 inhibitors/inducers (theoretical)

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

May enhance hypotensive effect; caution advised.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, cardiogenic shock, left ventricular failure with low filling pressure, hypotension, concurrent use with PDE-5 inhibitors or riociguat.

📊 Monitoring Parameters

Blood pressure, heart rate, ECG, symptoms of angina.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose Management

Symptomatic and supportive; monitor blood pressure and heart rate; may require vasopressors.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for davaindia nicorandil 5mg tablet

View All

Alternative brands with exact same active ingredient (Nicorandil (5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.