davaindia nicorandil 5mg tablet - Nicorandil (5mg) medicine

davaindia nicorandil 5mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Davaindia Generic Pharmacy ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is davaindia nicorandil 5mg tablet used for?

Alcoran (Nicorandil) is used to treat CARDIAC. It contains Nicorandil (5mg), which Nicorandil is a potassium channel activator and a nitrate-like vasodilator. It o. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Nicorandil
  • Manufacturer: Davaindia Generic Pharmacy
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š davaindia nicorandil 5mg tablet Uses & Benefits

Prophylaxis and long-term treatment of angina pectoris.

Off-label uses: Raynaud's phenomenon, heart failure (limited evidence).

๐Ÿ“‹ Drug Information

Generic Name(s)Nicorandil
Brand NameAlcoran
ManufacturerDavaindia Generic Pharmacy
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassPotassium channel opener
Route of AdministrationOral.
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed after oral administration.
DistributionWidely distributed; volume of distribution approximately 1.4 L/kg.
Protein BindingApproximately 25% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via denitration and glucuronidation.
Half-LifeApproximately 1 hour (parent drug); active metabolites have longer half-life.
ExcretionRenal excretion of metabolites; less than 1% excreted unchanged.
BioavailabilityApproximately 75-80% due to first-pass metabolism.
Onset of ActionWithin 30 minutes.
Peak Plasma Time0.5-1 hour.
Duration of ActionUp to 12 hours.

How It Works

Nicorandil is a potassium channel activator and a nitrate-like vasodilator. It opens ATP-sensitive potassium channels in vascular smooth muscle, leading to hyperpolarization and relaxation, and also acts as a nitric oxide donor, increasing cGMP.

Mechanism Steps

1Binds to ATP-sensitive potassium channels on vascular smooth muscle cells.
2Opens K_ATP channels, causing potassium efflux and membrane hyperpolarization.
3Hyperpolarization closes voltage-gated calcium channels, reducing calcium influx.

๐Ÿ’ก How to Take davaindia nicorandil 5mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of davaindia nicorandil 5mg tablet

โœ… Common Side Effects

  • Headache
  • Flushing
  • Dizziness
  • Nausea
  • Vomiting

๐Ÿšจ Serious Side Effects

  • Hypotension
  • Reflex tachycardia
  • Angioedema
  • Hepatic dysfunction

โš ๏ธ Rare Side Effects

  • Oral ulceration
  • Gastrointestinal bleeding
  • Myocardial ischemia (paradoxical)

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Sildenafil Major Severe hypotension
Riociguat Major Severe hypotension
Alcohol Moderate Additive vasodilation and hypotension

๐Ÿšจ Major Interactions

  • Phosphodiesterase-5 inhibitors (e.g., sildenafil)
  • Soluble guanylate cyclase stimulators (e.g., riociguat)

โšก Moderate Interactions

  • Antihypertensives
  • Alcohol
  • Nitrates

โ„น๏ธ Minor Interactions

  • CYP3A4 inhibitors/inducers (theoretical)

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

May enhance hypotensive effect; caution advised.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, cardiogenic shock, left ventricular failure with low filling pressure, hypotension, concurrent use with PDE-5 inhibitors or riociguat.

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, ECG, symptoms of angina.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised.

๐Ÿ’Š Overdose Management

Symptomatic and supportive; monitor blood pressure and heart rate; may require vasopressors.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for davaindia nicorandil 5mg tablet

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Alternative brands with exact same active ingredient (Nicorandil (5mg)):

Medical Note: Always consult your doctor before switching medications.

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