Mesalazine 1200 mg Immediate-Release Tablet: Comprehensive Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
- High fever with sore throat
- Severe diarrhea with dehydration
If experiencing severe symptoms, call emergency services immediately.
What is davaindia mesalazine 1200mg tablet pr used for?
Mesalazine 1200 mg immediate-release tablet is an anti-inflammatory medicine used to treat ulcerative colitis by reducing inflammation in the colon. It helps relieve symptoms like diarrhea, rectal bleeding, and abdominal pain, and is also used to maintain remission.
- Generic Name: Mesalazine
- Manufacturer: Davaindia Generic Pharmacy
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 davaindia mesalazine 1200mg tablet pr के बारे में (Hindi Summary)
उपयोग: यह दवा मेसलाज़ीन (5-एमिनोसैलिसिलिक एसिड) 1200 मिलीग्राम की तत्काल रिलीज़ गोली है, जिसका उपयोग अल्सरेटिव कोलाइटिस (बड़ी आंत की सूजन) के इलाज के लिए किया जाता है। यह आंत की सूजन को कम करके दस्त, पेट दर्द, और मल में खून आने जैसे लक्षणों से राहत दिलाती है। यह दवा रोग को ठीक नहीं करती, लेकिन लक्षणों को नियंत्रित रखने और बीमारी को दोबारा भड़कने से रोकने में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में सिरदर्द, जी मिचलाना, उल्टी, दस्त, पेट दर्द और गैस शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी गुर्दे की समस्या, खून की बीमारी या एलर्जी जैसे गंभीर दुष्प्रभाव हो सकते हैं। अगर आपको असामान्य चोट लगना, खून बहना, बुखार, गले में खराश या पेट में तेज दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। अगर आपको गुर्दे या लीवर की बीमारी है, तो डॉक्टर को जरूर बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर की सलाह के बिना यह दवा न लें। इस दवा को डॉक्टर की सलाह के बिना अचानक बंद न करें, क्योंकि इससे लक्षण फिर से बढ़ सकते हैं। दवा को ठंडी और सूखी जगह पर, बच्चों की पहुंच से दूर रखें।
💊 davaindia mesalazine 1200mg tablet pr Uses & Benefits
[{"condition":"Ulcerative Colitis (mild to moderate active disease)","description":"This medicine is used to treat active episodes of ulcerative colitis by reducing inflammation in the lining of the colon, leading to relief from symptoms such as diarrhea, rectal bleeding, and abdominal pain.","evidence":"Well-established"},{"condition":"Maintenance of remission in Ulcerative Colitis","description":"This medicine is used to maintain remission and prevent recurrence of ulcerative colitis symptoms in patients who have responded to initial treatment.","evidence":"Well-established"},{"condition":"Crohn's Disease (limited evidence)","description":"Sometimes used in the management of Crohn's disease, particularly for maintaining remission after surgery, but evidence is less robust than for ulcerative colitis.","evidence":"Limited"}]
Off-label uses: [{"condition":"Diverticular disease","description":"May be prescribed off-label to reduce inflammation in diverticular disease, but evidence is limited.","evidence":"Limited"},{"condition":"Radiation proctitis","description":"Occasionally used to manage inflammation of the rectum caused by radiation therapy, but this is not a standard approved use.","evidence":"Limited"}]
Primary treatment for: Ulcerative Colitis
Also treats: Crohn's Disease, Inflammatory Bowel Disease
📋 Drug Information
| Generic Name(s) | Mesalazine |
| Brand Name | Asacus Sachet |
| Manufacturer | Davaindia Generic Pharmacy |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | 5- Aminosalicylic acid (5-ASA) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Mesalazine is recommended by the World Health Organization (WHO) for the treatment of mild to moderate ulcerative colitis and for maintenance of remission. It is included in the WHO Model List of Essential Medicines. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) guidelines for inflammatory bowel disease recommend mesalazine as first-line therapy for mild to moderate ulcerative colitis and for maintenance of remission. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Mesalazine works by reducing inflammation in the lining of the gastrointestinal tract. It is thought to inhibit the production of inflammatory mediators such as prostaglandins and leukotrienes, and to scavenge free radicals, thereby decreasing the inflammatory response in the colon. Unlike some other anti-inflammatory drugs, mesalazine acts locally in the gut rather than throughout the body, which helps to minimize systemic side effects.
Mechanism Steps
💡 How to Take davaindia mesalazine 1200mg tablet pr
Strength: Immediate-release tablet, 1200 mg
Dosage Information
| Adult Dosage | The usual adult dose for active ulcerative colitis is 2.4 to 4.8 grams per day, divided into 2 to 4 doses, depending on the severity of the condition. For maintenance of remission, the dose is typically 1.2 to 2.4 grams per day. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on kidney and liver function. Start with a lower dose and monitor closely. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Regular monitoring of kidney function is recommended. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is 4.8 grams per day, but this may vary based on the clinical situation. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of davaindia mesalazine 1200mg tablet pr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| NSAIDs | Moderate | |
| Azathioprine | Moderate | |
| 6-Mercaptopurine | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Methotrexate
- NSAIDs (e.g., ibuprofen, naproxen)
⚡ Moderate Interactions
- Azathioprine
- 6-Mercaptopurine
🍷 Alcohol Interaction
Alcohol may increase the risk of gastrointestinal side effects such as stomach bleeding and may worsen the underlying condition. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to mesalazine, other salicylates, or any component of the formulation","Severe kidney impairment (e.g., severe renal failure)","Severe liver impairment","Blood dyscrasias (e.g., severe anemia, leukopenia)","Children under 2 years of age (safety not established)"]
⚠️ Warnings & Precautions
["Use with caution in patients with mild to moderate kidney or liver impairment; dose adjustment may be needed.","Patients with pyloric stenosis may have delayed release of the medicine.","May cause false-positive results in some urine tests for normetanephrine.","Avoid use in patients with a history of allergy to sulfasalazine.","Do not use in patients with active peptic ulcer disease.","Elderly patients may be more sensitive to side effects; monitor closely."]
🤱 Lactation Safety
Mesalazine is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose with mesalazine may cause symptoms such as nausea, vomiting, diarrhea, and abdominal pain. In severe cases, it may lead to kidney or liver damage. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have kidney or liver problems, as this medicine can affect kidney function and regular monitoring may be necessary. Do not take this medicine if you are allergic to mesalazine, other salicylates, or any of the other ingredients. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. This medicine may interact with other medicines, including certain antibiotics, blood thinners, and non-steroidal anti-inflammatory drugs (NSAIDs). Always tell your doctor about all the medicines you are taking. Do not stop taking this medicine without consulting your doctor, even if you feel better, as stopping suddenly may cause your symptoms to return. Keep this medicine out of the reach of children and store it in its original packaging at room temperature, away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially kidney problems. Regular monitoring of kidney function is advised. Dose adjustment may be necessary based on renal function.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor. This medicine is generally considered safe during pregnancy and is often continued to keep the disease under control. Uncontrolled inflammation may be more harmful to the pregnancy than the medicine itself.
🏥 Post-Surgery Considerations
After surgery, continue taking this medicine as prescribed unless your doctor advises otherwise. Inform your surgeon about all medicines you are taking. This medicine does not typically interfere with wound healing.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It does not usually cause bleeding problems, but if you have any blood disorder, your dentist may take precautions. No dose adjustment is typically needed for dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you experience fatigue, dizziness, or abdominal pain, avoid strenuous activities and consult your doctor. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or fatigue, avoid these activities until you feel better. It should not interfere with your daily work or social life, but you may need to take it at regular intervals, which can be managed with planning.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or if your doctor decides to discontinue it, follow their instructions. Stopping suddenly can lead to a flare-up of your condition.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and well-tolerated. However, regular monitoring of kidney function is recommended, as rare cases of kidney problems have been reported. Liver function may also be monitored if symptoms occur. Long-term use does not cause dependency. It is important to continue taking the medicine as prescribed to maintain remission and prevent flare-ups.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Certain diets, such as low-FODMAP or specific carbohydrate diet, may help manage symptoms in some people.
Evidence: LimitedProbiotics may help restore gut flora balance and reduce inflammation, but evidence is mixed.
Evidence: LimitedStress reduction techniques like yoga and meditation can help improve quality of life.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are on other immunosuppressive medicines, live vaccines may be contraindicated. Consult your doctor before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine may take several days to weeks to show its full effect. You may start noticing improvement in symptoms within a few days, but it may take longer for complete relief. Continue taking it as prescribed.
A: Yes, taking this medicine with food is recommended to reduce stomach upset and nausea.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is generally considered safe during pregnancy when taken as prescribed. However, consult your doctor for personalized advice.
A: No, do not stop taking this medicine without consulting your doctor. Stopping suddenly can cause your symptoms to return.
A: Rarely, this medicine can affect kidney function. Your doctor may monitor your kidney function with blood tests before and during treatment.
A: It is advisable to avoid or limit alcohol consumption while taking this medicine, as it may increase gastrointestinal side effects.
A: Seek immediate medical attention if you experience severe abdominal pain, bloody diarrhea, decreased urine output, unusual bleeding, or allergic reactions such as swelling of the face or throat.
🤔 Common Patient Concerns
🔄 Substitutes for davaindia mesalazine 1200mg tablet pr
View AllAlternative brands with exact same active ingredient:
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mosart tablet drCadila Pharmaceuticals Ltd ₹58.60 34.9% CHEAPER
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mesavin 1200mg tabletAlniche Life Sciences Pvt Ltd ₹179.13 99% COSTLIER
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procol od 1200mg tabletDelvin Formulations Pvt Ltd ₹189.30 110.3% COSTLIER
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zemakool od 1200mg tabletAlembic Pharmaceuticals Ltd ₹199.00 121.1% COSTLIER
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mesloc 1200 tablet drCare Formulation Labs Pvt Ltd ₹214.00 137.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Mesalazine is a painkiller.
Fact: Mesalazine is not a painkiller; it is an anti-inflammatory medicine that works locally in the gut to reduce inflammation. - Myth: Mesalazine can cure ulcerative colitis.
Fact: Mesalazine helps control symptoms and maintain remission but does not cure ulcerative colitis. It is a chronic condition that requires ongoing management. - Myth: You can stop mesalazine once you feel better.
Fact: Stopping mesalazine suddenly can lead to a flare-up of symptoms. Always consult your doctor before stopping. - Myth: Mesalazine is safe for everyone.
Fact: Mesalazine is not suitable for people with certain kidney, liver, or blood disorders. Always consult a doctor before use.
🔄 Alternative Options
Generic Alternatives
- Mesalazine 1200 mg tablet (various manufacturers)
Brand Alternatives
- Coolgut Tablet PR
- Mesacol 1200 mg Tablet
- Pentasa 1 g Tablet
- Asacol 1200 mg Tablet
- Salofalk 1200 mg Tablet