davaindia ketoconazole 200mg tablet - Ketoconazole (200mg) medicine

davaindia ketoconazole 200mg tablet

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🏭 Davaindia Generic Pharmacy 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

What is davaindia ketoconazole 200mg tablet used for?

This medicine contains Ketoconazole (200mg) and is used to treat OPHTHAL OTOLOGICALS. Inhibits fungal CYP450 14α-demethylase, blocking ergosterol synthesis and disrupting fungal cell me. Always consult your doctor before use.

  • Generic Name: Ketoconazole
  • Manufacturer: Davaindia Generic Pharmacy
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 davaindia ketoconazole 200mg tablet Uses & Benefits

Dandruff, seborrheic dermatitis, tinea versicolor, and fungal infections of the scalp.

Off-label uses: Tinea capitis, Candidal intertrigo, Pityriasis versicolor

📋 Drug Information

Generic Name(s)Ketoconazole
Brand NameAzolbest-KT Shampoo
ManufacturerDavaindia Generic Pharmacy
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL OTOLOGICALS
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationTopical (shampoo)
StorageStore at 20-25°C (68-77°F); protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMinimal systemic absorption when applied topically; approximately 0.1% of dose absorbed through scalp skin.
DistributionDistributed mainly in skin and hair; negligible systemic distribution due to low absorption.
Protein Binding99% bound to plasma proteins (mainly albumin) if absorbed systemically.
MetabolismHepatic via CYP3A4; extensive first-pass metabolism if absorbed.
Half-Life2-4 hours (systemic); not applicable for topical use.
ExcretionPrimarily feces (biliary) and urine (renal) for absorbed fraction.
BioavailabilityNegligible (<0.5%) after topical application.
Onset of ActionWithin 1-2 weeks of regular use for antifungal effect.
Peak Plasma TimeNot applicable due to minimal systemic absorption.
Duration of ActionSustained antifungal effect with regular use; remains on hair and scalp for days.

How It Works

Inhibits fungal CYP450 14α-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane integrity.

Mechanism Steps

1Ketoconazole enters fungal cell via diffusion.
2Binds to fungal CYP450 14α-demethylase (ERG11).
3Inhibits conversion of lanosterol to ergosterol.
4Depletes ergosterol in fungal cell membrane.
5Accumulates toxic 14α-methylated sterols.
6Disrupts membrane integrity and function.
7Leads to fungal cell death.

💡 How to Take davaindia ketoconazole 200mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of davaindia ketoconazole 200mg tablet

✅ Common Side Effects

Scalp irritation
Dryness
Oiliness
Hair discoloration
Pruritus

🚨 Serious Side Effects

Severe allergic reaction (rash, urticaria, angioedema)
Hepatotoxicity (rare)

⚠️ Rare Side Effects

Contact dermatitis
Hair loss
Alopecia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased INR and bleeding risk if systemic absorption occurs.
CYP3A4 substrates Major Increased plasma levels of substrate drugs.
Cisapride Major Risk of QT prolongation and cardiac arrhythmias.
Terfenadine Major Risk of QT prolongation.
Astemizole Major Risk of QT prolongation.

🚨 Major Interactions

  • Warfarin
  • CYP3A4 substrates (e.g., midazolam, triazolam)
  • Cisapride
  • Terfenadine
  • Astemizole

⚡ Moderate Interactions

  • Oral hypoglycemics
  • Anticoagulants
  • Phenytoin
  • Rifampin
  • Isoniazid

🍷 Alcohol Interaction

No known interaction with topical use.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to ketoconazole or any component; avoid on broken or inflamed skin.

🤱 Lactation Safety

Excretion in breast milk unknown; use with caution on small areas.

💊 Overdose Management

Unlikely with topical use; accidental ingestion may cause nausea, vomiting; symptomatic treatment.

⏰ Missed Dose

Apply as soon as remembered; skip if almost time for next dose; do not double dose.

🔄 Substitutes for davaindia ketoconazole 200mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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