davaindia gliclazide 60mg tablet er - Gliclazide (60mg) medicine

Diamicron XR 60 Tablet: Complete Medicine Guide

No reviews yet
🏭 Davaindia Generic Pharmacy 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for type 2 diabetes.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe hypoglycemia with confusion, seizures, or loss of consciousness
  • Signs of a severe allergic reaction such as rash, swelling of face, lips, or throat, or difficulty breathing
  • Yellowing of skin or eyes, dark urine, or severe abdominal pain
  • Unusual bleeding or bruising
  • Persistent nausea, vomiting, or diarrhea
  • Rapid heartbeat or palpitations with weakness

If experiencing severe symptoms, call emergency services immediately.

What is davaindia gliclazide 60mg tablet er used for?

This medicine is a modified-release oral antidiabetic tablet containing gliclazide 60 mg. It is used to treat type 2 diabetes by stimulating insulin release from the pancreas. It is taken once daily with breakfast.

  • Generic Name: Gliclazide
  • Manufacturer: Davaindia Generic Pharmacy
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 davaindia gliclazide 60mg tablet er के बारे में (Hindi Summary)

उपयोग: यह दवा टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए इस्तेमाल की जाती है। यह शरीर में इंसुलिन का स्तर बढ़ाकर ब्लड शुगर को कंट्रोल करने में मदद करती है। इसे आमतौर पर नाश्ते के साथ दिन में एक बार लिया जाता है। यह दवा उन लोगों के लिए है जिनका ब्लड शुगर सिर्फ डाइट और एक्सरसाइज से कंट्रोल नहीं हो पाता। इसे डॉक्टर की सलाह के बिना बंद न करें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में लो ब्लड शुगर (हाइपोग्लाइसीमिया), वजन बढ़ना, जी मिचलाना और पेट में हल्की तकलीफ शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको बेहोशी, दौरे, या सांस लेने में तकलीफ हो तो तुरंत डॉक्टर से मिलें। लो ब्लड शुगर के लक्षण दिखने पर तुरंत मीठा खाएं।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर नाश्ते के साथ। खाली पेट न लें। लो ब्लड शुगर से बचने के लिए समय पर खाना खाएं। शराब न पिएं। अपने ब्लड शुगर की नियमित जांच करें। अगर आपको चक्कर आना, पसीना आना या घबराहट हो तो तुरंत मीठा खाएं और डॉक्टर को बताएं। इस दवा को बच्चों से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 davaindia gliclazide 60mg tablet er Uses & Benefits

[{"condition":"Type 2 Diabetes Mellitus","description":"This medicine is used to improve blood sugar control in adults with type 2 diabetes when diet and exercise alone are not sufficient.","evidence":"Well-established"},{"condition":"Type 2 Diabetes Mellitus with Metformin","description":"This medicine may be used in combination with metformin or other oral antidiabetic agents for better glycemic control.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Gestational Diabetes","description":"Sometimes used off-label in gestational diabetes when other treatments are not suitable, but only under specialist care.","evidence":"Limited"}]

Primary treatment for: Type 2 Diabetes Mellitus

Also treats: Metabolic syndrome, Obesity

📋 Drug Information

Generic Name(s)Gliclazide
Brand NameAzukon MR 60 Tablet
ManufacturerDavaindia Generic Pharmacy
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassSulfonylureas (Insulin Secretogogues)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with breakfast at the same time each day to maintain steady blood levels.
2
Always carry a fast-acting sugar source like glucose tablets or candy to treat low blood sugar.
3
Monitor your blood sugar regularly as advised by your doctor.
4
Avoid alcohol while taking this medicine as it increases the risk of hypoglycemia.
5
Inform your doctor about all other medicines you take, especially beta-blockers and diuretics.
6
Do not skip meals while on this medicine.
7
Report any unusual symptoms like persistent dizziness, confusion, or palpitations to your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood sugar (hyperglycemia)
This medicine is prescribed to lower blood sugar in type 2 diabetes.
Likely Use
✅
Frequent urination and excessive thirst
These are symptoms of high blood sugar that this medicine helps control.
Likely Use
❌
Fever
This medicine is not used to treat fever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract. The modified-release formulation is designed to release gliclazide gradually, which helps maintain steady plasma levels. Food does not significantly affect the extent of absorption.
DistributionGliclazide is distributed throughout the body, with a volume of distribution of approximately 30 liters. It is about 95% bound to plasma proteins.
Protein BindingApproximately 95% bound to plasma proteins.
MetabolismGliclazide is extensively metabolized in the liver, primarily by cytochrome P450 2C9. The metabolites are inactive.
Half-LifeThe elimination half-life is approximately 10 to 12 hours.
ExcretionGliclazide and its metabolites are primarily excreted in the urine (about 60-70%) and feces (about 10-20%).
BioavailabilityThe bioavailability of gliclazide from the modified-release formulation is approximately 97%.
Onset of ActionThe onset of action is within 2 to 4 hours after oral administration.
Peak Plasma TimePeak plasma concentration is reached approximately 6 to 8 hours after dosing.
Duration of ActionThe hypoglycemic effect lasts for about 24 hours, allowing once-daily dosing.

How It Works

This medicine lowers blood glucose by stimulating pancreatic beta cells to release insulin. It binds to specific receptors on the beta-cell membrane, causing closure of ATP-sensitive potassium channels. This leads to depolarization of the cell membrane, opening of voltage-gated calcium channels, and influx of calcium. The increased intracellular calcium triggers the release of insulin from stored granules. Additionally, this medicine may improve peripheral insulin sensitivity and reduce hepatic glucose production.

Mechanism Steps

1
Binding to beta-cell receptor: This medicine binds to the sulfonylurea receptor (SUR1) on the ATP-sensitive potassium channel of pancreatic beta cells.
2
Channel closure and depolarization: Binding closes the potassium channel, causing the cell membrane to depolarize.
3
Calcium influx: Depolarization opens voltage-gated calcium channels, allowing calcium to enter the beta cell.
4
Insulin release: Increased intracellular calcium triggers the release of insulin from secretory granules.
5
Blood glucose reduction: The released insulin helps move glucose into cells and reduces blood sugar levels.

💡 How to Take davaindia gliclazide 60mg tablet er

Strength: Modified-release tablet, 60 mg

1Take this medicine once daily with breakfast.
2Swallow the tablet whole with a glass of water.
3Do not crush or chew the tablet.
4Take at the same time each day to maintain steady blood levels.
5If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual starting dose is 30 mg once daily with breakfast. The dose may be increased to 60 mg or 120 mg once daily based on blood glucose response. The maximum recommended dose is 120 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the hypoglycemic effects. Start with a lower dose and monitor blood glucose closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with mild to moderate renal impairment. In severe renal impairment, this medicine is contraindicated. Dose adjustment may be needed based on renal function.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. In severe hepatic impairment, this medicine is contraindicated. Monitor liver function regularly.
Maximum Daily Dose120 mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Breakfast
Take with breakfast
Reduces the risk of hypoglycemia and stomach upset.
Alcohol
Avoid
Increases the risk of low blood sugar and can cause disulfiram-like reaction.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of davaindia gliclazide 60mg tablet er

✅ Common Side Effects

Hypoglycemia (Common (5-10%))
Treat with fast-acting sugar if symptoms occur. Consult your doctor if episodes are frequent.
Weight gain (Common (5-10%))
Maintain a healthy diet and regular exercise. Consult your doctor if weight gain is significant.
Nausea (Common (1-5%))
Take with food to reduce nausea. Consult your doctor if it persists.
Stomach discomfort (Common (1-5%))
Take with meals. Consult your doctor if it continues.

🚨 Serious Side Effects

Severe hypoglycemia (Rare (<0.1%))
Seek immediate medical attention if you experience confusion, seizures, or loss of consciousness.
Blood disorders (e.g., anemia, leukopenia, thrombocytopenia) (Rare (<0.1%))
Report unusual bruising, bleeding, or fatigue to your doctor immediately.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you develop rash, swelling, or difficulty breathing.
Liver problems (e.g., jaundice) (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or abdominal pain to your doctor.

⚠️ Rare Side Effects

Hemolytic anemia
Seek medical attention if you experience unusual tiredness or pale skin.
Porphyria cutanea tarda
Consult a doctor if you notice blistering or skin fragility.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Miconazole Major
Phenylbutazone Major
Beta-blockers Major
Fluconazole Moderate
ACE inhibitors Moderate
Diuretics Moderate
Corticosteroids Moderate
Alcohol Minor
Rifampicin Minor

🚨 Major Interactions

  • Miconazole
  • Phenylbutazone
  • Beta-blockers

⚡ Moderate Interactions

  • Fluconazole
  • ACE inhibitors
  • Diuretics
  • Corticosteroids

🍷 Alcohol Interaction

Alcohol may increase the risk of hypoglycemia and can cause a disulfiram-like reaction with flushing, nausea, and palpitations. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal or hepatic impairment","Known hypersensitivity to gliclazide or other sulfonylureas","Pregnancy and breastfeeding","Concomitant use with miconazole"]

⚠️ Warnings & Precautions

["Risk of hypoglycemia, especially in elderly, malnourished, or those with renal/hepatic impairment.","May cause weight gain.","Use with caution in patients with G6PD deficiency due to risk of hemolytic anemia.","Avoid alcohol consumption.","Not recommended for use in children.","May impair ability to drive or operate machinery if hypoglycemia occurs."]

🤱 Lactation Safety

This medicine is not recommended during breastfeeding as it may pass into breast milk and cause hypoglycemia in the infant. Consult your doctor for alternative treatments.

💊 Overdose Management

Overdose can cause severe hypoglycemia. Symptoms include confusion, seizures, and loss of consciousness. Immediate treatment with intravenous glucose is required. Seek emergency medical attention.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed, usually once daily with breakfast. Do not skip meals while taking this medicine, as this increases the risk of low blood sugar. Carry a source of fast-acting sugar, such as glucose tablets or candy, at all times in case of hypoglycemia. Avoid alcohol, as it can increase the risk of low blood sugar and stomach upset. Inform your doctor about all other medicines you take, especially beta-blockers, diuretics, and other diabetes medicines. Check your blood sugar regularly as advised. Do not drive or operate machinery if you feel shaky or confused due to low blood sugar. Keep this medicine out of reach of children. Do not stop taking this medicine without consulting your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of hypoglycemia. Start with a lower dose and monitor blood sugar closely. Regular kidney function tests are recommended.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor. This medicine is not recommended during pregnancy; insulin is the preferred treatment.

🏥 Post-Surgery Considerations

After surgery, blood sugar control is important. Your doctor may adjust your diabetes medicine, including this one, based on your condition. Monitor blood sugar closely.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. Dental procedures may affect your eating schedule, so monitor blood sugar and adjust as advised by your doctor.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight through diet and exercise.
🥗
Eat regular meals and do not skip breakfast.
😴
Engage in regular physical activity like walking or swimming.
💧
Monitor your blood sugar regularly as advised.
🧘
Avoid alcohol and smoking.
🌞
Get adequate sleep and manage stress.

🏋️ Exercise Considerations

Exercise can lower blood sugar. Check your blood sugar before exercising and carry a fast-acting sugar source. Adjust your medicine dose if advised by your doctor.

🥗 Diet Recommendations

Eat a balanced diet rich in fiber, fruits, and vegetables.
Limit intake of refined sugars and processed foods.
Include whole grains, lean proteins, and healthy fats.
Stay hydrated with water.
Avoid skipping meals.

💼 Impact on Daily Work & Life

This medicine may cause low blood sugar, which can affect your ability to drive or operate machinery. Be cautious and carry a sugar source. Inform your employer about your condition if necessary.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your blood sugar is well-controlled with lifestyle changes, your doctor may adjust or stop the medicine.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to weight gain and increased risk of hypoglycemia. Regular monitoring of blood sugar, kidney and liver function is necessary. It may also cause blood disorders rarely. Your doctor may adjust the dose over time based on your condition.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet and exercise are essential for managing type 2 diabetes and can reduce the need for medicines.

Evidence: Well-established
Other oral antidiabetics

Metformin, DPP-4 inhibitors, SGLT2 inhibitors, etc., may be alternatives based on individual needs.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, maintain routine vaccinations as advised for people with diabetes.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in the original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Keep a supply of fast-acting sugar with you. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with type 2 diabetes for 5 years
He was prescribed this medicine after metformin alone did not control his blood sugar. He took it regularly with breakfast and monitored his blood sugar. Within 3 months, his HbA1c improved significantly. He experienced mild hypoglycemia once when he skipped breakfast, but he learned to carry glucose tablets.
💡 Lesson: Taking this medicine with breakfast and regular monitoring helps achieve good blood sugar control and prevents hypoglycemia.
👤 A 62-year-old woman with type 2 diabetes and mild kidney disease
She was started on a lower dose of this medicine due to her kidney function. She was advised to monitor her blood sugar more frequently. She maintained good control without any severe side effects.
💡 Lesson: Dose adjustment and close monitoring are important in elderly patients with kidney impairment to prevent hypoglycemia.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood sugar within a few hours, but it may take several weeks to see the full effect on your overall blood sugar control.

Q: Can I take this medicine with other diabetes medicines?

A: Yes, it can be used with other diabetes medicines like metformin, but only under your doctor's supervision. Your doctor may adjust the doses.

Q: What should I do if I experience low blood sugar?

A: If you feel symptoms of low blood sugar such as shakiness, sweating, or confusion, immediately eat or drink something sweet like glucose tablets, candy, or fruit juice. Then inform your doctor.

Q: Is this medicine safe during pregnancy?

A: This medicine is not recommended during pregnancy. Insulin is usually preferred. Consult your doctor if you are pregnant or planning to become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for davaindia gliclazide 60mg tablet er

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure diabetes.
    Fact: This medicine helps control blood sugar but does not cure diabetes. Lifestyle changes and ongoing treatment are necessary.
  • Myth: This medicine can be taken without food.
    Fact: This medicine should be taken with breakfast to reduce the risk of hypoglycemia.
  • Myth: This medicine is safe for everyone with diabetes.
    Fact: It is not suitable for people with type 1 diabetes, severe kidney or liver disease, or those allergic to sulfonylureas.

🔄 Alternative Options

Generic Alternatives

  • Gliclazide 60 mg modified-release tablet

Brand Alternatives

  • Diamicron XR 60 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Gliclazide MR","class":"Sulfonylurea","frequency":"Once daily","hypoglycemia_risk":"Moderate","weight_effect":"Weight gain"},{"medicine":"Glimepiride","class":"Sulfonylurea","frequency":"Once daily","hypoglycemia_risk":"Moderate to high","weight_effect":"Weight gain"},{"medicine":"Metformin","class":"Biguanide","frequency":"Twice daily","hypoglycemia_risk":"Low","weight_effect":"Weight neutral or loss"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory