danavish atorvastatin+fenofibrate tablet - Atorvastatin (10mg) + Fenofibrate (160mg) medicine

danavish atorvastatin+fenofibrate tablet

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🏭 Danavish Healthcare πŸ“¦ Varies by brand πŸ’Š Allopathy πŸ“… Updated: Sep 21, 2026
⚠️ Hepatotoxicity Risk πŸ“‹ Prescription Required πŸ’Š Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

What is danavish atorvastatin+fenofibrate tablet used for?

This medicine contains Atorvastatin (10mg) + Fenofibrate (160mg) and is used to treat CARDIAC. Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Fenofibrate activates PPARοΏ½. Always consult your doctor before use.

  • Generic Name: Atorvastatin + Fenofibrate
  • Manufacturer: Danavish Healthcare
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
πŸ’‘ Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

πŸ’Š danavish atorvastatin+fenofibrate tablet Uses & Benefits

Primary hypercholesterolemia, mixed dyslipidemia, hypertriglyceridemia.

Off-label uses: Secondary prevention of cardiovascular events, non-alcoholic fatty liver disease.

πŸ“‹ Drug Information

Generic Name(s)Atorvastatin + Fenofibrate
Brand NameAtorlip-F Tablet
ManufacturerDanavish Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassLipid-lowering agents (Statin + Fibrate)
Route of AdministrationOral
StorageStore at 20-25Β°C, protect from light and moisture.
Shelf LifeAs per manufacturer

πŸ”¬ How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAtorvastatin: Rapidly absorbed after oral administration; Fenofibrate: Well absorbed, absorption enhanced with food.
DistributionAtorvastatin: Extensively distributed to tissues; Fenofibrate: Highly bound to albumin.
Protein BindingAtorvastatin: β‰₯98%; Fenofibrate: ~99%
MetabolismAtorvastatin: Hepatic via CYP3A4; Fenofibrate: Hydrolysis to fenofibric acid, then glucuronidation.
Half-LifeAtorvastatin: ~14 hours; Fenofibrate: ~20 hours (fenofibric acid)
ExcretionAtorvastatin: Biliary (feces); Fenofibrate: Renal (urine) as metabolites.
BioavailabilityAtorvastatin: ~14%; Fenofibrate: ~30% (increased with food)
Onset of ActionAtorvastatin: 1-2 weeks for lipid changes; Fenofibrate: Several days to weeks.
Peak Plasma TimeAtorvastatin: 1-2 hours; Fenofibrate: 6-8 hours (fenofibric acid)
Duration of ActionAtorvastatin: Up to 24 hours; Fenofibrate: Up to 24 hours.

How It Works

Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Fenofibrate activates PPARΞ±, increasing lipolysis and VLDL clearance.

Mechanism Steps

1Atorvastatin competitively inhibits HMG-CoA reductase, reducing mevalonate and cholesterol synthesis.
2Fenofibrate activates PPARΞ±, increasing lipoprotein lipase activity and fatty acid oxidation.
3Combined effect: Decreased hepatic VLDL secretion, increased clearance of triglycerides, and upregulation of LDL receptors.

πŸ’‘ How to Take danavish atorvastatin+fenofibrate tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of danavish atorvastatin+fenofibrate tablet

βœ… Common Side Effects

Myalgia
Diarrhea
Nasopharyngitis
Headache
Abdominal pain

🚨 Serious Side Effects

Rhabdomyolysis
Hepatotoxicity
Pancreatitis
Renal failure
Angioedema

⚠️ Rare Side Effects

Peripheral neuropathy
Interstitial lung disease
Tendon rupture
Gynecomastia

Consult your doctor if you experience any unusual symptoms.

πŸ”¬ Drug Interactions

Drug Severity Effect
Warfarin Major Increased INR and bleeding risk
Cyclosporine Major Increased risk of myopathy/rhabdomyolysis
Gemfibrozil Major Increased risk of myopathy
Macrolide antibiotics Major Increased atorvastatin levels
Azole antifungals Major Increased atorvastatin levels
HIV protease inhibitors Major Increased atorvastatin levels
Digoxin Moderate Increased digoxin levels
Oral contraceptives Moderate Increased contraceptive levels
Colchicine Moderate Increased risk of myopathy
Niacin Moderate Increased risk of myopathy
Antacids Minor Reduced atorvastatin absorption
Rifampin Minor Reduced atorvastatin levels
St. John's Wort Minor Reduced atorvastatin levels

🚨 Major Interactions

  • Warfarin
  • Cyclosporine
  • Gemfibrozil
  • Macrolide antibiotics
  • Azole antifungals
  • HIV protease inhibitors

⚑ Moderate Interactions

  • Digoxin
  • Oral contraceptives
  • Colchicine
  • Fibrates (other)
  • Niacin

🍷 Alcohol Interaction

May increase risk of hepatotoxicity; avoid excessive alcohol.

πŸ›‘οΈ Safety & Warnings

🚫 Contraindications

Active liver disease, unexplained LFT elevations, pregnancy, lactation, hypersensitivity, severe renal impairment.

🀱 Lactation Safety

Contraindicated; excreted in milk.

πŸ’Š Overdose Management

Supportive care; monitor liver and renal function; no specific antidote.

⏰ Missed Dose

Take as soon as remembered unless near next dose; skip if close.

πŸ”„ Substitutes for danavish atorvastatin+fenofibrate tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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