d-ventin 50 tablet sr - Desvenlafaxine (50mg) medicine

d-veniz 50 Tablet ER: Complete Guide to Uses, Side Effects, and Safety

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🏭 D D Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Thoughts of harming yourself or others
  • Severe agitation, confusion, or hallucinations
  • Rapid heartbeat, fever, and muscle rigidity (signs of serotonin syndrome)
  • Unusual bleeding or bruising
  • Severe headache with vision changes
  • Seizures
  • Signs of an allergic reaction such as rash, swelling, or difficulty breathing

If experiencing severe symptoms, call emergency services immediately.

What is d-ventin 50 tablet sr used for?

This medicine is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder in adults. It works by increasing the levels of serotonin and norepinephrine in the brain, which helps improve mood and emotional balance. The usual dose is 50 mg once daily, and it may take several weeks to show full effects.

  • Generic Name: Desvenlafaxine
  • Manufacturer: D D Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 d-ventin 50 tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा डिप्रेशन (अवसाद) और चिंता के इलाज के लिए इस्तेमाल की जाती है। यह मस्तिष्क में सेरोटोनिन और नॉरएपिनेफ्रिन नामक रसायनों के स्तर को संतुलित करने में मदद करती है, जिससे मूड बेहतर होता है और मानसिक तनाव कम होता है। यह आमतौर पर वयस्कों में मेजर डिप्रेसिव डिसऑर्डर के लिए प्रिस्क्राइब की जाती है। इस दवा का असर दिखने में कुछ हफ्ते लग सकते हैं, इसलिए इसे नियमित रूप से लेना जरूरी है।

साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे मतली, चक्कर आना, मुंह सूखना, पसीना आना, नींद न आना और यौन समस्याएं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको बेचैनी, तेज धड़कन, बुखार, मांसपेशियों में अकड़न, या असामान्य रक्तस्राव हो, तो तुरंत डॉक्टर से संपर्क करें। इस दवा को अचानक बंद न करें, क्योंकि इससे withdrawal symptoms हो सकते हैं।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी पूरी मेडिकल हिस्ट्री बताएं, खासकर अगर आपको हाई ब्लड प्रेशर, दिल की बीमारी, लिवर या किडनी की समस्या, या ब्लीडिंग डिसऑर्डर है। इस दवा को शराब के साथ न लें। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। इस दवा को बच्चों की पहुंच से दूर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 d-ventin 50 tablet sr Uses & Benefits

[{"condition":"Major Depressive Disorder","description":"This medicine is approved for the treatment of major depressive disorder in adults, helping to improve mood, energy, and overall emotional well-being.","evidence":"Well-established"},{"condition":"Generalized Anxiety Disorder","description":"Sometimes prescribed off-label for generalized anxiety disorder, although it is not specifically approved for this condition in all regions.","evidence":"Moderate"},{"condition":"Panic Disorder","description":"May be used off-label to reduce the frequency and severity of panic attacks in some patients.","evidence":"Limited"},{"condition":"Social Anxiety Disorder","description":"Occasionally used off-label to help manage symptoms of social anxiety, but evidence is limited.","evidence":"Limited"}]

Off-label uses: [{"condition":"Migraine Prophylaxis","description":"Sometimes prescribed off-label to help prevent migraines, especially in patients who also have depression.","evidence":"Limited"},{"condition":"Neuropathic Pain","description":"May be used off-label for certain types of chronic nerve pain, though evidence is not robust.","evidence":"Limited"},{"condition":"Premenstrual Dysphoric Disorder","description":"Occasionally used off-label for severe premenstrual symptoms, but not a first-line treatment.","evidence":"Limited"}]

Primary treatment for: Major Depressive Disorder

Also treats: Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder

📋 Drug Information

Generic Name(s)Desvenlafaxine
Brand NameD-Veniz 50 Tablet ER
ManufacturerD D Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSerotonin-norepinephrine reuptake inhibitors (SNRIs)
Route of AdministrationOral
StorageStore at room temperature between 20°C and 25°C (68°F to 77°F). Keep away from moisture and heat. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Do not stop this medicine abruptly; your doctor will gradually reduce the dose to prevent withdrawal symptoms.
3
Monitor your mood and report any worsening depression or suicidal thoughts to your doctor immediately.
4
Check your blood pressure regularly, as this medicine can cause a modest increase.
5
Avoid alcohol while taking this medicine to reduce drowsiness and dizziness.
6
If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose.
7
Inform your doctor if you experience sexual side effects, as dose adjustment or alternative treatment may help.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Persistent sadness or low mood
This medicine is commonly prescribed for major depressive disorder.
Likely Use
✅
Loss of interest in activities
This medicine can help improve interest and pleasure in daily activities.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Anxiety
This medicine may be used off-label for anxiety disorders.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed after oral administration, with a bioavailability of approximately 80%. Food does not significantly affect its absorption.
DistributionIt has a large volume of distribution, indicating extensive distribution into body tissues. It is not highly bound to plasma proteins.
Protein BindingApproximately 30% bound to plasma proteins.
MetabolismThis medicine undergoes extensive metabolism in the liver, primarily via conjugation (glucuronidation) and oxidation by CYP3A4. It is also metabolized by CYP2D6 to a lesser extent. No active metabolites are formed.
Half-LifeThe elimination half-life is approximately 11 hours.
ExcretionAbout 45% of the dose is excreted unchanged in the urine, and 19% is excreted as glucuronide conjugates. The remainder is excreted as other metabolites.
BioavailabilityApproximately 80%
Onset of ActionThe onset of therapeutic effect may take 1 to 4 weeks, with full benefits often seen after 6 to 8 weeks.
Peak Plasma TimeApproximately 7.5 hours after oral administration.
Duration of ActionThe effects last for approximately 24 hours, allowing for once-daily dosing.

How It Works

This medicine works by inhibiting the reuptake of serotonin and norepinephrine in the brain. By blocking the transporters responsible for reabsorbing these neurotransmitters, it increases their availability in the synaptic cleft, which helps to improve mood and emotional balance. Unlike some other antidepressants, it has minimal effect on dopamine reuptake and does not significantly affect histamine or muscarinic receptors, which may result in fewer side effects such as sedation and dry mouth.

Mechanism Steps

1
Binding to serotonin transporter: This medicine binds to the serotonin transporter protein on presynaptic neurons, blocking the reuptake of serotonin back into the nerve cell.
2
Binding to norepinephrine transporter: It also binds to the norepinephrine transporter, preventing the reuptake of norepinephrine, thereby increasing its concentration in the synapse.
3
Increased neurotransmitter availability: As a result, more serotonin and norepinephrine remain in the synaptic cleft, enhancing neurotransmission.
4
Downstream neuroadaptive changes: Over time, this leads to changes in receptor sensitivity and neuroplasticity, which are thought to underlie the therapeutic effects in depression and anxiety.

💡 How to Take d-ventin 50 tablet sr

Strength: 50 mg extended-release tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
3You can take it with or without food. If it upsets your stomach, take it with a meal.
4Take it at the same time each day to maintain consistent levels in your body.
5Do not stop taking this medicine suddenly without consulting your doctor, as it may cause withdrawal symptoms.

Dosage Information

Adult DosageThe usual recommended dose of this medicine for adults is 50 mg once daily, with or without food. Some patients may benefit from a lower starting dose of 25 mg once daily for the first week. The dose may be increased by your doctor based on your response and tolerability, but the maximum recommended dose is 100 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without consulting your doctor.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, particularly hyponatremia and falls. Dose adjustment may be necessary based on renal function. Close monitoring is recommended.
Renal ImpairmentFor patients with mild to moderate renal impairment, dose adjustment is not usually necessary. For severe renal impairment (CrCl <30 mL/min), the dose should not exceed 50 mg every other day. Consult your doctor for personalized dosing.
Hepatic ImpairmentFor patients with mild to moderate hepatic impairment, dose adjustment is not usually necessary. For severe hepatic impairment, the dose should not exceed 50 mg every other day. Consult your doctor for personalized dosing.
Maximum Daily Dose100 mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Can be taken with or without food
Food does not significantly affect absorption, but taking with food may reduce nausea.
Grapefruit
Avoid or consume in moderation
Grapefruit can inhibit CYP3A4, potentially increasing drug levels and side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of d-ventin 50 tablet sr

✅ Common Side Effects

Nausea (Common (10-20%))
Take with food to reduce nausea. If it persists, consult your doctor.
Dizziness (Common (10-15%))
Avoid driving or operating machinery until you know how this medicine affects you.
Dry mouth (Common (10-15%))
Stay hydrated and chew sugar-free gum. Consult your doctor if it becomes bothersome.
Insomnia (Common (10-15%))
Take the medicine in the morning to minimize sleep disturbance. Practice good sleep hygiene.
Excessive sweating (Common (10-15%))
Stay cool and hydrated. Consult your doctor if it interferes with daily activities.
Sexual dysfunction (Common (10-20%))
Discuss with your doctor; dose adjustment or alternative medication may be considered.

🚨 Serious Side Effects

Serotonin syndrome (Rare (<0.1%))
Seek immediate medical attention if you experience agitation, hallucinations, rapid heartbeat, fever, or muscle rigidity.
Increased blood pressure (Uncommon (1-5%))
Monitor blood pressure regularly. Consult your doctor if you have persistent high readings.
Abnormal bleeding (Rare (<0.1%))
Report any unusual bruising or bleeding to your doctor immediately.
Low sodium levels (hyponatremia) (Rare (<0.1%))
Seek medical attention if you experience confusion, headache, or weakness.
Suicidal thoughts (Uncommon (1-5%))
Contact your doctor or a mental health professional immediately if you have thoughts of harming yourself.

⚠️ Rare Side Effects

Angle-closure glaucoma
Seek immediate medical attention if you experience eye pain, vision changes, or swelling around the eyes.
Seizures
Call emergency services if a seizure occurs.
Severe allergic reactions
Seek emergency help if you experience rash, swelling, or difficulty breathing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Warfarin Major
Aspirin/NSAIDs Major
Tramadol Major
Ketoconazole Moderate
Rifampin Moderate
Diuretics Moderate
Alcohol Minor
Grapefruit juice Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Other serotonergic drugs (e.g., SSRIs, SNRIs, triptans, tramadol)
  • Anticoagulants (e.g., warfarin) and antiplatelet drugs (e.g., aspirin, NSAIDs)

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)
  • Diuretics

🍷 Alcohol Interaction

Alcohol may increase the sedative effects of this medicine, such as drowsiness and dizziness. It is advisable to avoid alcohol while taking this medicine to prevent worsening of side effects and potential impairment of judgment.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to desvenlafaxine or any component of the formulation","Concurrent use of monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI","Use in children and adolescents under 18 years of age (unless directed by a specialist)"]

⚠️ Warnings & Precautions

["May increase the risk of suicidal thoughts and behaviors, especially in young adults. Close monitoring is required.","Can cause serotonin syndrome, particularly when used with other serotonergic drugs. Seek immediate medical attention if symptoms occur.","May increase blood pressure. Monitor blood pressure regularly.","Can cause abnormal bleeding, especially when used with anticoagulants or antiplatelet drugs.","May cause hyponatremia, particularly in elderly patients. Monitor sodium levels.","Do not stop abruptly; taper gradually to avoid withdrawal symptoms.","Use with caution in patients with bipolar disorder, as it may precipitate a manic episode.","May impair judgment, thinking, or motor skills. Avoid driving or operating machinery until you know how it affects you."]

🤱 Lactation Safety

This medicine is excreted in breast milk in small amounts. Caution is advised when used during breastfeeding. Consult your doctor to discuss the potential risks and benefits.

💊 Overdose Management

In case of overdose, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, rapid heartbeat, drowsiness, and serotonin syndrome. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and cardiac rhythm.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have a history of high blood pressure, heart disease, liver or kidney problems, bleeding disorders, or bipolar disorder. This medicine may increase the risk of suicidal thoughts, especially in young adults, so close monitoring by a healthcare professional is essential during the initial phase of treatment. Avoid consuming alcohol while taking this medicine as it can worsen side effects such as drowsiness and dizziness. Do not drive or operate heavy machinery until you know how this medicine affects you. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits with your doctor. Do not share this medicine with others, even if they have similar symptoms. Store this medicine at room temperature, away from moisture and heat, and keep it out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, particularly hyponatremia, dizziness, and falls. Dose adjustment may be necessary based on renal function. Regular monitoring of blood pressure and sodium levels is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking or continuing this medicine. The risks and benefits should be carefully weighed. Some studies suggest a potential risk of complications, but more research is needed. Do not stop the medicine without medical advice.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may interact with certain anesthetic agents and can increase the risk of bleeding. Your doctor may advise you to temporarily stop the medicine before surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may increase the risk of bleeding and interact with certain medications used in dentistry. Your dentist may take precautions or adjust your treatment plan.

💚 Lifestyle Tips for Better Results

🏃
Maintain a regular sleep schedule to support mood stability.
🥗
Engage in regular physical activity, such as walking or yoga, to boost serotonin levels.
😴
Practice stress-reduction techniques like deep breathing or meditation.
💧
Stay connected with friends and family for emotional support.
🧘
Avoid alcohol and recreational drugs, as they can worsen depression and interact with this medicine.
🌞
Eat a balanced diet rich in fruits, vegetables, and whole grains.

🏋️ Exercise Considerations

Exercise is generally safe while taking this medicine, but start slowly if you have been inactive. Stay hydrated, especially if you sweat excessively. If you experience dizziness or increased heart rate, stop and consult your doctor. Avoid strenuous activities until you know how the medicine affects you.

🥗 Diet Recommendations

Include omega-3 fatty acids from fish or flaxseed to support brain health.
Reduce intake of processed foods and refined sugars.
Stay well hydrated throughout the day.
Limit caffeine, as it may increase anxiety or insomnia.
Eat regular meals to maintain stable blood sugar levels.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, dizziness, or difficulty concentrating, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. It is important to inform your employer if your job requires such activities. With time, most people adjust and can resume normal activities. If side effects persist, consult your doctor for dose adjustment.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your doctor decides to discontinue, the dose will be gradually tapered to prevent withdrawal symptoms. If you wish to stop for any reason, discuss with your doctor first.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored by a healthcare professional. Regular follow-up is important to assess efficacy and monitor for side effects such as blood pressure changes, sexual dysfunction, and hyponatremia. Some patients may experience weight changes. Do not stop the medicine without medical advice, as abrupt discontinuation can cause withdrawal symptoms. Your doctor may periodically reassess the need for continued treatment.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cognitive Behavioral Therapy (CBT)

A type of talk therapy that can be as effective as medication for mild to moderate depression and can complement drug treatment.

Evidence: Well-established
Regular Exercise

Physical activity can boost mood and reduce symptoms of depression.

Evidence: Well-established
Mindfulness and Meditation

These practices can help reduce stress and improve emotional well-being.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions reported with this medicine. However, it is always advisable to inform your healthcare provider about all medications you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (20-25°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight and moisture

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. If crossing time zones, adjust the timing of your dose gradually to match your new schedule, but consult your doctor first. Store at room temperature and avoid exposing to extreme heat or moisture. Check local customs regulations for carrying prescription medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with major depressive disorder
She started this medicine as prescribed by her psychiatrist. Initially, she experienced mild nausea and dizziness, which subsided after a week. By the fourth week, she noticed a significant improvement in her mood and energy levels. She emphasized the importance of taking the medicine at the same time every day and not missing doses.
💡 Lesson: Consistency and patience are key when starting this medicine. Side effects often diminish with time, and full benefits may take several weeks.
👤 A 50-year-old man with depression and anxiety
He was prescribed this medicine for depression and anxiety. He initially felt more anxious, but his doctor reassured him that this could happen early on. After 6 weeks, his anxiety reduced, and he felt more in control. He also started therapy, which helped him cope better.
💡 Lesson: Combining medication with therapy can enhance outcomes. Early side effects may occur but often improve with continued use.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine may start to improve symptoms within 1 to 2 weeks, but full therapeutic effects usually take 6 to 8 weeks. It is important to continue taking it as prescribed.

Q: Can I stop taking this medicine suddenly?

A: No, you should not stop this medicine abruptly as it can cause withdrawal symptoms such as anxiety, irritability, and flu-like symptoms. Your doctor will gradually reduce the dose.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is this medicine safe during pregnancy?

A: The safety of this medicine during pregnancy is not fully established. Consult your doctor to weigh the benefits and risks.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol while taking this medicine as it can increase drowsiness and dizziness.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Will I gain weight on this medicine?
  • Is it safe to take during pregnancy?

🔄 Substitutes for d-ventin 50 tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is addictive.
    Fact: This medicine is not considered addictive in the traditional sense, but it can cause withdrawal symptoms if stopped abruptly. It should be tapered gradually under medical supervision.
  • Myth: This medicine works immediately.
    Fact: This medicine may take 1 to 4 weeks to start working, and full benefits may take 6 to 8 weeks. It is important to continue taking it as prescribed.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You should not stop taking this medicine without consulting your doctor, even if you feel better. Stopping abruptly can cause withdrawal symptoms and relapse of depression.

🔄 Alternative Options

Generic Alternatives

  • Desvenlafaxine succinate

Brand Alternatives

  • Pristiq
  • Desvenlafaxine ER

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","class":"SNRI","primary_use":"Major Depressive Disorder","usual_dose":"50 mg once daily","half_life":"11 hours"},{"medicine":"Venlafaxine","class":"SNRI","primary_use":"Major Depressive Disorder, Anxiety","usual_dose":"75-225 mg daily","half_life":"5 hours (active metabolite 11 hours)"},{"medicine":"Duloxetine","class":"SNRI","primary_use":"Depression, Neuropathic Pain, Fibromyalgia","usual_dose":"60 mg once daily","half_life":"12 hours"},{"medicine":"Sertraline","class":"SSRI","primary_use":"Depression, Anxiety, OCD, PTSD","usual_dose":"50-200 mg daily","half_life":"26 hours"}]

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