amis 100mg tablet allopathy (Amisulpride (100mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
amis 100mg tablet allopathy (Amisulpride (100mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by D D Pharmaceuticals. Contains Amisulpride (100mg).

amis 100mg tablet - Uses, Price, Side Effects & Substitutes

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Amisulpride (100mg) (Click to see all medicines with same salt)
🏭 D D Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is amis 100mg tablet used for?

Amisant 200 Tablet (Amisulpride) is used to treat Schizophrenia (positive and negative symptoms); acute psychotic episodes; maintenance therapy.. It contains Amisulpride (100mg), which Selective antagonist at dopamine D2 and D3 receptors, with higher affinity for D. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Amisulpride
  • Manufacturer: D D Pharmaceuticals
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 amis 100mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

amis 100mg tablet का उपयोग मुख्य रूप से neuro cns और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Amisulpride (100mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

📋 Drug Information

Generic Name(s)Amisulpride
Brand NameAmisant 200 Tablet
ManufacturerD D Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassAtypical Antipsychotics
Route of AdministrationOral
StorageStore at room temperature (15-30°C), protected from light and moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration, with peak plasma concentrations reached within 1-4 hours. Bioavailability is approximately 48% due to first-pass metabolism.
DistributionWidely distributed throughout the body; crosses the blood-brain barrier. Volume of distribution is about 5.8 L/kg.
Protein BindingApproximately 16% bound to plasma proteins.
MetabolismMetabolized in the liver, primarily via CYP3A4, to inactive metabolites. Minor metabolism via other pathways.
Half-LifeApproximately 12 hours (range 10-14 hours).
ExcretionPrimarily excreted in urine (about 70% as unchanged drug and metabolites) and feces (about 20%).
Bioavailability48%
Onset of ActionTherapeutic effects may be observed within a few days to weeks, but full antipsychotic effect may ta
Peak Plasma Time1-4 hours
Duration of ActionApproximately 24 hours due to once-daily dosing.

Pharmacodynamics

Mechanism of ActionSelective antagonist at dopamine D2 and D3 receptors, with higher affinity for D3 receptors. It also has some antagonistic activity at serotonin 5-HT2A receptors.
Target ReceptorDopamine D2 and D3 receptors (primarily D3); also 5-HT2A serotonin receptors.
Pharmacodynamic EffectsAntipsychotic effect by blocking dopamine receptors in the mesolimbic system; low propensity for extrapyramidal symptoms at low doses; may cause sedation, weight gain, and prolactin elevation.

💡 How and when to take amis 100mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (15-30°C), protected from light and moisture.

⚙️ How amis 100mg tablet Works

Selective antagonist at dopamine D2 and D3 receptors, with higher affinity for D3 receptors. It also has some antagonistic activity at serotonin 5-HT2A receptors.

1 Amisulpride selectively binds to dopamine D2 and D3 receptors, with higher affinity for D3.
⬇️
2 Blocks dopamine receptors in the mesolimbic system, reducing positive symptoms of schizophrenia.
⬇️
3 At low doses, preferentially blocks presynaptic D2/D3 autoreceptors, increasing dopamine release in prefrontal cortex, improving negative symptoms.
⬇️
4 Also antagonizes serotonin 5-HT2A receptors, contributing to its antipsychotic profile.
⬇️
5 The net effect is modulation of dopaminergic and serotonergic neurotransmission.

💊 amis 100mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Schizophrenia (positive and negative symptoms); acute psychotic episodes; maintenance therapy.

Off-label uses: Bipolar depression, anxiety disorders, obsessive-compulsive disorder (limited evidence).

⚠️ What are the side effects of amis 100mg tablet?

✅ Common Side Effects

  • Insomnia
  • Anxiety
  • Agitation
  • Weight gain
  • Constipation
  • Nausea
  • Dry mouth
  • Sedation

🚨 Serious Side Effects

  • QT prolongation
  • Torsades de pointes
  • Neuroleptic malignant syndrome
  • Seizures
  • Tardive dyskinesia
  • Prolactin elevation (galactorrhea, gynecomastia)

⚠️ Rare Side Effects

  • Hepatotoxicity
  • Agranulocytosis
  • Venous thromboembolism
  • Pancreatitis
  • Allergic reactions

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Levodopa Major Antagonism of dopaminergic effects; reduced efficacy of levodopa.
QT-prolonging drugs Major Increased risk of ventricular arrhythmias.
CYP3A4 inhibitors Major Increased amisulpride plasma concentration; risk of toxicity.
Antihypertensives Moderate Additive hypotensive effect.
CNS depressants Moderate Enhanced sedation and respiratory depression.
Lithium Moderate Increased risk of neurotoxicity.
Antacids Minor Possible reduced absorption of amisulpride.
Cimetidine Minor Slight increase in amisulpride levels.

🚨 Major Interactions

  • Levodopa
  • Dopamine agonists
  • QT-prolonging drugs
  • CYP3A4 inhibitors

⚡ Moderate Interactions

  • Antihypertensives
  • CNS depressants
  • Lithium

ℹ️ Minor Interactions

  • Antacids
  • Cimetidine

🍽️ Food Interactions

Food may delay absorption but does not significantly affect bioavailability.

🍷 Alcohol Interaction

Alcohol may enhance CNS depressant effects; avoid concurrent use.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to amisulpride; concomitant use with prolactin-dependent tumors; known QT prolongation; severe renal impairment (CrCl <10 mL/min); pheochromocytoma.

📊 Monitoring Parameters

ECG (QT interval), blood pressure, liver function tests, renal function, prolactin levels, extrapyramidal symptoms.

🤱 Lactation Safety

Not recommended; amisulpride is excreted in breast milk and may cause adverse effects in the infant.

💊 Overdose Management

Supportive care; ECG monitoring; activated charcoal if recent ingestion; no specific antidote; treat arrhythmias as needed.

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

🛑 Myths vs. Facts about amis 100mg tablet

  • Myth: Generic substitutes of amis 100mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Amisulpride (100mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of amis 100mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

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