cytoheart od 60mg tablet - Uses, Price, Side Effects & Substitutes
What is cytoheart od 60mg tablet used for?
Accardi MR Tablet MR (Trimetazidine) is used to treat CARDIAC. It contains Trimetazidine (60mg), which Inhibits long-chain 3-ketoacyl-CoA thiolase, shifting myocardial energy metaboli. Always consult your doctor before use. Take as prescribed.
- Generic Name: Trimetazidine
- Manufacturer: Gracious Biotech
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cytoheart od 60mg tablet Uses & Benefits
Adjunctive therapy for stable angina pectoris; also used for vertigo and tinnitus (off-label in some regions).
Off-label uses: Vertigo, Tinnitus, Diabetic cardiomyopathy
๐ Drug Information
| Generic Name(s) | Trimetazidine |
| Brand Name | Accardi MR Tablet MR |
| Manufacturer | Gracious Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Fatty acid modulator & Sodium channel blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits long-chain 3-ketoacyl-CoA thiolase, shifting myocardial energy metabolism from fatty acid oxidation to glucose oxidation, thereby improving cardiac efficiency under ischemic conditions.
Mechanism Steps
๐ก How to Take cytoheart od 60mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cytoheart od 60mg tablet
โ Common Side Effects
- Dizziness
- Headache
- Gastrointestinal disturbances (nausea, vomiting, diarrhea)
- Asthenia
๐จ Serious Side Effects
- Parkinsonism
- Tremor
- Gait instability
- Restless leg syndrome
- Severe bradycardia
โ ๏ธ Rare Side Effects
- Allergic reactions (rash, urticaria)
- Hepatitis
- Thrombocytopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Paroxetine | Major | Increased trimetazidine plasma concentration due to CYP2D6 inhibition |
| Ketoconazole | Major | Increased trimetazidine plasma concentration due to CYP3A4 inhibition |
| Warfarin | Moderate | Possible increased anticoagulant effect; monitor INR |
| Metoprolol | Moderate | Additive bradycardia and hypotension |
๐จ Major Interactions
- CYP2D6 inhibitors (e.g., paroxetine, fluoxetine)
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
โก Moderate Interactions
- Antihypertensives (additive hypotensive effect)
- Beta-blockers
- Calcium channel blockers
โน๏ธ Minor Interactions
- Antacids
- Food (delayed absorption)
๐ฝ๏ธ Food Interactions
Food may delay absorption but does not significantly affect overall bioavailability.
๐ท Alcohol Interaction
No significant interaction reported; however, alcohol may exacerbate angina symptoms.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to trimetazidine or excipients; Parkinson's disease, parkinsonian symptoms, tremors, restless leg syndrome; severe renal impairment (CrCl <30 mL/min).
๐ Monitoring Parameters
Blood pressure, heart rate, ECG, renal function, liver function tests.
๐คฑ Lactation Safety
Excreted in breast milk; avoid use or discontinue breastfeeding.
๐ Overdose Management
No specific antidote; symptomatic and supportive treatment. Gastric lavage if recent ingestion.
โฐ Missed Dose
Take as soon as remembered unless almost time for next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cytoheart od 60mg tablet
View AllAlternative brands with exact same active ingredient (Trimetazidine (60mg)):
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myovedon 60mg tablet srAurobindo Pharma Ltd โน56.25 62.7% CHEAPER
-
Taz 60mg Tablet SROrchid Chemicals & Pharmaceuticals Ltd โน62.86 58.4% CHEAPER
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isvedon 60mg tablet crLife Medicare & Biotech Pvt Ltd โน75.00 50.3% CHEAPER
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Trilong 60mg CapsuleElder Pharmaceuticals Ltd โน75.72 49.8% CHEAPER
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metagard 60mg tabletIpca Laboratories Ltd โน75.94 49.7% CHEAPER
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kadrin 60mg tablet srZee Laboratories โน84.38 44.1% CHEAPER
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cardimax sr tabletUSV Ltd โน117.56 22.1% CHEAPER
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trizid sr tabletAretaeus Pharmaceuticals โน152.46 1% COSTLIER
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cytocon sr 60mg tabletConcertina Pharma Pvt Ltd โน156.00 3.4% COSTLIER
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redon-cr 60 tablet crRaymedica Pharmaceuticals โน177.19 17.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.