Isvedon 60mg Tablet CR (Trimetazidine): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain that does not respond to nitrates
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- New or worsening tremors, stiffness, or difficulty walking
- Fainting or severe dizziness
If experiencing severe symptoms, call emergency services immediately.
What is isvedon 60mg tablet cr used for?
This medicine is a prescription oral tablet containing Trimetazidine 60 mg in a controlled-release form. It is used as add-on therapy for stable angina pectoris to reduce angina attacks and improve exercise tolerance. It works by shifting the heart's energy metabolism to use glucose more efficiently, which requires less oxygen. It is not for immediate relief of acute angina attacks.
- Generic Name: Trimetazidine (60mg)
- Manufacturer: Life Medicare & Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 isvedon 60mg tablet cr के बारे में (Hindi Summary)
उपयोग: यह दवा ट्राइमेटाजिडीन 60 मिलीग्राम का नियंत्रित-रिलीज़ टैबलेट है। इसका उपयोग स्थिर एनजाइना (सीने में दर्द) के इलाज में सहायक दवा के रूप में किया जाता है। यह हृदय की ऊर्जा उत्पादन प्रक्रिया को बदलकर अधिक कुशल बनाती है, जिससे कम ऑक्सीजन में भी हृदय बेहतर काम करता है। यह दवा तीव्र एनजाइना के दौरे के लिए नहीं है। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, पेट दर्द, दस्त, अपच, मतली और उल्टी शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। दुर्लभ मामलों में पार्किंसन जैसे लक्षण, बेचैन पैर, गिरना, और निम्न रक्तचाप हो सकता है। यदि आपको असामान्य हलचल, मांसपेशियों में अकड़न, या संतुलन की समस्या हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। गोली को पूरा निगलें, चबाएं या तोड़ें नहीं। इसे भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन पेट की परेशानी से बचने के लिए भोजन के साथ लेना बेहतर है। डॉक्टर की सलाह के बिना दवा बंद न करें। चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीन चलाने से बचें। यदि आपको गुर्दे, या पार्किंसन रोग की समस्या है तो डॉक्टर को बताएं। तीव्र एनजाइना के लिए इस दवा का उपयोग न करें।
💊 isvedon 60mg tablet cr Uses & Benefits
[{"condition":"Stable angina pectoris","description":"Used as add-on therapy to reduce the frequency of angina attacks and improve exercise tolerance in patients not adequately controlled by first-line anti-anginal medicines.","evidence":"Well-established"},{"condition":"Ischemic heart disease","description":"Helps improve myocardial energy metabolism and reduce ischemic burden in patients with coronary artery disease.","evidence":"Moderate"},{"condition":"Chorioretinal vascular disorders","description":"Sometimes used to improve visual function in ischemic retinal conditions, though evidence is limited.","evidence":"Limited"},{"condition":"Vertigo and tinnitus of vascular origin","description":"May be prescribed for dizziness and ringing in the ears believed to be due to reduced blood flow, but evidence is not robust.","evidence":"Limited"}]
Off-label uses: [{"condition":"Chronic heart failure","description":"Some studies suggest benefit in improving symptoms and cardiac function, but it is not a standard treatment.","evidence":"Limited"},{"condition":"Peripheral arterial disease","description":"Occasionally used to improve walking distance in patients with claudication, but evidence is insufficient.","evidence":"Limited"}]
Primary treatment for: Stable angina pectoris
Also treats: Ischemic heart disease, Chorioretinal vascular disorders, Vertigo of vascular origin, Tinnitus of vascular origin
📋 Drug Information
| Generic Name(s) | Trimetazidine (60mg) |
| Brand Name | isvedon 60mg tablet cr |
| Manufacturer | Life Medicare & Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Fatty acid modulator & Sodium channel blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the enzyme long-chain 3-ketoacyl-CoA thiolase, which is involved in fatty acid beta-oxidation in the mitochondria of heart muscle cells. By blocking this enzyme, it shifts the heart's energy production from fatty acid oxidation to glucose oxidation. Glucose oxidation is more oxygen-efficient, meaning the heart can produce more energy per unit of oxygen consumed. This helps the heart muscle continue to function better when blood supply is reduced, as in angina. Additionally, this medicine reduces the accumulation of toxic fatty acid intermediates and helps maintain cellular pH and calcium handling, further protecting heart cells from ischemic damage.
Mechanism Steps
💡 How to Take isvedon 60mg tablet cr
Strength: Controlled-release tablet containing 60 mg of Trimetazidine.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 60 mg taken orally twice daily, or as directed by your doctor. The controlled-release formulation may be prescribed as 60 mg once daily in some cases. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and clinical response. Do not adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and movement disorders. Dose adjustment may be necessary based on renal function. Regular monitoring is advised. |
| Renal Impairment | In patients with moderate renal impairment (creatinine clearance 30-60 mL/min), dose reduction may be considered. This medicine is contraindicated in severe renal impairment (creatinine clearance <30 mL/min). Consult your doctor for personalized dosing. |
| Hepatic Impairment | No specific dose adjustment is established for patients with hepatic impairment. Use with caution and monitor liver function. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 120 mg, but the usual maximum is 60 mg twice daily. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of isvedon 60mg tablet cr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Nitrates | Moderate | |
| Beta-blockers | Moderate | |
| Calcium channel blockers | Moderate | |
| MAOIs | Major | |
| CYP3A4 inhibitors | Moderate | |
| CYP3A4 inducers | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Other anti-anginal medicines (e.g., nitrates, beta-blockers, calcium channel blockers)
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, low blood pressure, and fainting while taking this medicine. It is advisable to avoid or limit alcohol consumption. Consult your doctor for personalized advice.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Trimetazidine or any component of the formulation","Parkinson's disease, parkinsonian symptoms, tremors, restless legs syndrome","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["This medicine is not for immediate relief of acute angina attacks. Keep fast-acting nitrates available.","May cause or worsen parkinsonian symptoms. Discontinue if symptoms occur and consult a neurologist.","Use with caution in elderly patients due to increased risk of falls and movement disorders.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with mild to moderate renal impairment; dose adjustment may be needed.","Inform your doctor if you have a history of low blood pressure or are taking antihypertensive medicines.","Do not stop this medicine abruptly without medical advice."]
🤱 Lactation Safety
Not established from the available information. It is not known whether this medicine is excreted in human breast milk. Breastfeeding women should consult their doctor before using this medicine.
💊 Overdose Management
There is limited information on overdose with this medicine. In case of suspected overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Monitor vital signs and provide appropriate care. Dialysis is unlikely to be effective due to high protein binding.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water; do not crush, chew, or break it because it is a controlled-release formulation. You may take it with or without food, but taking it with food may reduce stomach upset. Do not stop taking this medicine suddenly without consulting your doctor, as this may worsen your angina. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause dizziness. Inform your doctor if you have kidney problems, liver problems, or a history of Parkinson's disease. Do not use this medicine to treat an acute angina attack; keep your fast-acting nitrate medicine available for that purpose. Tell your doctor about all other medicines you are taking, especially other anti-anginal drugs. Pregnant or breastfeeding women should consult their doctor before using this medicine. Store this medicine at room temperature, away from moisture and direct sunlight, and keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at increased risk of dizziness, falls, and parkinsonian symptoms. Dose adjustment may be needed based on renal function. Regular monitoring of neurological symptoms and kidney function is advised. Caution should be taken when standing up to avoid falls.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. The safety of this medicine in pregnancy is not established. Your doctor will weigh the potential benefits and risks.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be temporarily stopped or adjusted. Follow your doctor's instructions regarding when to resume.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are established, but it is important for your dental care team to know your complete medication list.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or low blood pressure, which can affect your ability to exercise safely. Avoid strenuous activities until you know how the medicine affects you. Always warm up and cool down. If you experience chest pain, dizziness, or shortness of breath during exercise, stop and seek medical advice.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Most people can continue their normal work activities with caution. Inform your employer if your job involves operating heavy machinery.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as parkinsonian symptoms, severe dizziness, or allergic reactions, contact your doctor immediately. Your doctor will decide whether to adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well-tolerated. However, rare cases of parkinsonian symptoms, restless legs syndrome, and falls have been reported, especially in elderly patients. Regular monitoring of renal function, liver function, and neurological symptoms is advised. Periodic review with your doctor is necessary to assess continued benefit and adjust treatment as needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Heart-healthy diet, regular exercise, smoking cessation, and stress management can complement medicine for angina.
Evidence: Well-establishedSupervised exercise and education programs can improve cardiovascular health.
Evidence: Well-establishedAngioplasty or bypass surgery may be considered for severe coronary artery disease.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, consult your doctor about adjusting dosing times. Check local customs regulations for carrying prescription medicines. Carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine may take several days to weeks to show its full effect. It is not for immediate relief of acute angina attacks.
A: It is often prescribed with other heart medicines, but interactions can occur. Always inform your doctor about all medicines you take.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, do not stop this medicine without consulting your doctor. Stopping suddenly may worsen your angina.
A: This medicine can cause or worsen parkinsonian symptoms in rare cases. If you experience tremors, stiffness, or difficulty walking, contact your doctor immediately.
🤔 Common Patient Concerns
🔄 Substitutes for isvedon 60mg tablet cr
View AllAlternative brands with exact same active ingredient:
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myovedon 60mg tablet srAurobindo Pharma Ltd ₹56.25 25% CHEAPER
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Taz 60mg Tablet SROrchid Chemicals & Pharmaceuticals Ltd ₹62.86 16.2% CHEAPER
-
Trilong 60mg CapsuleElder Pharmaceuticals Ltd ₹75.72 1% COSTLIER
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metagard 60mg tabletIpca Laboratories Ltd ₹75.94 1.3% COSTLIER
-
kadrin 60mg tablet srZee Laboratories ₹84.38 12.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for immediate relief of chest pain.
Fact: This medicine is not for acute angina attacks. It is used for long-term prevention and management. Keep fast-acting nitrates for acute attacks. - Myth: This medicine is safe for everyone with heart disease.
Fact: It is contraindicated in people with Parkinson's disease, parkinsonian symptoms, restless legs syndrome, and severe kidney problems. - Myth: You can stop this medicine once you feel better.
Fact: Do not stop this medicine without consulting your doctor. Stopping suddenly may worsen angina. - Myth: This medicine is a blood thinner.
Fact: This medicine is not a blood thinner. It works by improving heart muscle energy metabolism.
🔄 Alternative Options
Generic Alternatives
- Trimetazidine 60 mg controlled-release tablet
Brand Alternatives
- Isvedon 60 mg Tablet CR