isvedon 60mg tablet cr - Trimetazidine (60mg) medicine

Isvedon 60mg Tablet CR (Trimetazidine): Complete Medicine Guide

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🏭 Life Medicare & Biotech Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for stable angina as add-on therapy; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Oct 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain that does not respond to nitrates
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • New or worsening tremors, stiffness, or difficulty walking
  • Fainting or severe dizziness

If experiencing severe symptoms, call emergency services immediately.

What is isvedon 60mg tablet cr used for?

This medicine is a prescription oral tablet containing Trimetazidine 60 mg in a controlled-release form. It is used as add-on therapy for stable angina pectoris to reduce angina attacks and improve exercise tolerance. It works by shifting the heart's energy metabolism to use glucose more efficiently, which requires less oxygen. It is not for immediate relief of acute angina attacks.

  • Generic Name: Trimetazidine (60mg)
  • Manufacturer: Life Medicare & Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 isvedon 60mg tablet cr के बारे में (Hindi Summary)

उपयोग: यह दवा ट्राइमेटाजिडीन 60 मिलीग्राम का नियंत्रित-रिलीज़ टैबलेट है। इसका उपयोग स्थिर एनजाइना (सीने में दर्द) के इलाज में सहायक दवा के रूप में किया जाता है। यह हृदय की ऊर्जा उत्पादन प्रक्रिया को बदलकर अधिक कुशल बनाती है, जिससे कम ऑक्सीजन में भी हृदय बेहतर काम करता है। यह दवा तीव्र एनजाइना के दौरे के लिए नहीं है। इसे डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, पेट दर्द, दस्त, अपच, मतली और उल्टी शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। दुर्लभ मामलों में पार्किंसन जैसे लक्षण, बेचैन पैर, गिरना, और निम्न रक्तचाप हो सकता है। यदि आपको असामान्य हलचल, मांसपेशियों में अकड़न, या संतुलन की समस्या हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। गोली को पूरा निगलें, चबाएं या तोड़ें नहीं। इसे भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन पेट की परेशानी से बचने के लिए भोजन के साथ लेना बेहतर है। डॉक्टर की सलाह के बिना दवा बंद न करें। चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीन चलाने से बचें। यदि आपको गुर्दे, या पार्किंसन रोग की समस्या है तो डॉक्टर को बताएं। तीव्र एनजाइना के लिए इस दवा का उपयोग न करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 isvedon 60mg tablet cr Uses & Benefits

[{"condition":"Stable angina pectoris","description":"Used as add-on therapy to reduce the frequency of angina attacks and improve exercise tolerance in patients not adequately controlled by first-line anti-anginal medicines.","evidence":"Well-established"},{"condition":"Ischemic heart disease","description":"Helps improve myocardial energy metabolism and reduce ischemic burden in patients with coronary artery disease.","evidence":"Moderate"},{"condition":"Chorioretinal vascular disorders","description":"Sometimes used to improve visual function in ischemic retinal conditions, though evidence is limited.","evidence":"Limited"},{"condition":"Vertigo and tinnitus of vascular origin","description":"May be prescribed for dizziness and ringing in the ears believed to be due to reduced blood flow, but evidence is not robust.","evidence":"Limited"}]

Off-label uses: [{"condition":"Chronic heart failure","description":"Some studies suggest benefit in improving symptoms and cardiac function, but it is not a standard treatment.","evidence":"Limited"},{"condition":"Peripheral arterial disease","description":"Occasionally used to improve walking distance in patients with claudication, but evidence is insufficient.","evidence":"Limited"}]

Primary treatment for: Stable angina pectoris

Also treats: Ischemic heart disease, Chorioretinal vascular disorders, Vertigo of vascular origin, Tinnitus of vascular origin

📋 Drug Information

Generic Name(s)Trimetazidine (60mg)
Brand Nameisvedon 60mg tablet cr
ManufacturerLife Medicare & Biotech Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassFatty acid modulator & Sodium channel blocker
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture, or as indicated on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Swallow the tablet whole; do not crush, chew, or break it.
3
Avoid driving or operating machinery until you know how this medicine affects you.
4
Do not stop this medicine suddenly without consulting your doctor.
5
Keep fast-acting nitrate medicine available for acute angina attacks.
6
Report any unusual movement problems, tremors, or difficulty walking to your doctor immediately.
7
Stay well hydrated throughout the day.
8
Inform your doctor about all other medicines you are taking.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chest pain on exertion (angina)
This medicine is commonly prescribed as add-on therapy for stable angina.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Dizziness
This medicine may cause dizziness as a side effect, but it is not used to treat dizziness.
Not Primary
✅
Tinnitus (ringing in ears)
Sometimes prescribed for tinnitus of vascular origin, but evidence is limited.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed after oral administration. The controlled-release formulation is designed to provide a more sustained release of the active ingredient over time compared to immediate-release formulations. Food does not significantly affect the extent of absorption.
DistributionThis medicine is widely distributed in body tissues, including the heart, liver, and kidneys. It has a volume of distribution of approximately 4.8 L/kg. It crosses the blood-brain barrier to some extent.
Protein BindingPlasma protein binding of this medicine is relatively low, approximately 16%.
MetabolismThis medicine is primarily metabolized in the liver, mainly by cytochrome P450 enzymes, though specific isoenzymes are not fully characterized. It undergoes extensive first-pass metabolism.
Half-LifeThe elimination half-life of this medicine is approximately 7 to 12 hours in healthy adults. It may be prolonged in elderly patients and those with renal impairment.
ExcretionThis medicine and its metabolites are mainly excreted in the urine, with about 60-80% of an oral dose recovered in urine and a smaller amount in feces.
BioavailabilityThe oral bioavailability of this medicine is approximately 90% or higher, indicating good absorption.
Onset of ActionThe onset of anti-anginal effect is gradual, typically taking several days to weeks of regular use to achieve full therapeutic benefit. It is not intended for immediate relief of acute angina attacks.
Peak Plasma TimePeak plasma concentration is reached approximately 2 to 3 hours after oral administration of the controlled-release tablet.
Duration of ActionThe therapeutic effect of this medicine lasts for about 24 hours, allowing for twice-daily or once-daily dosing depending on the formulation and clinical judgment.

How It Works

This medicine works by inhibiting the enzyme long-chain 3-ketoacyl-CoA thiolase, which is involved in fatty acid beta-oxidation in the mitochondria of heart muscle cells. By blocking this enzyme, it shifts the heart's energy production from fatty acid oxidation to glucose oxidation. Glucose oxidation is more oxygen-efficient, meaning the heart can produce more energy per unit of oxygen consumed. This helps the heart muscle continue to function better when blood supply is reduced, as in angina. Additionally, this medicine reduces the accumulation of toxic fatty acid intermediates and helps maintain cellular pH and calcium handling, further protecting heart cells from ischemic damage.

Mechanism Steps

1
Inhibition of 3-KAT enzyme: This medicine binds to and inhibits long-chain 3-ketoacyl-CoA thiolase, a key enzyme in the mitochondrial fatty acid beta-oxidation pathway.
2
Shift to glucose oxidation: With fatty acid oxidation partially blocked, the heart muscle increases its use of glucose as an energy source, which is more oxygen-efficient.
3
Improved oxygen efficiency: Glucose oxidation produces more ATP per molecule of oxygen consumed, allowing the heart to maintain energy levels despite reduced blood flow.
4
Reduced ischemic damage: The shift in metabolism reduces accumulation of toxic fatty acid intermediates, decreases cellular acidosis, and protects heart cells from ischemic injury.
5
Clinical benefit: These cellular changes translate into reduced angina attacks, improved exercise capacity, and better overall cardiac function in patients with stable angina.

💡 How to Take isvedon 60mg tablet cr

Strength: Controlled-release tablet containing 60 mg of Trimetazidine.

1Swallow the tablet whole with a glass of water.
2Do not crush, chew, or break the tablet.
3Take with or without food, but with food if it upsets your stomach.
4Take at the same times each day to maintain consistent levels.
5If you miss a dose, follow the missed dose instructions.
6Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 60 mg taken orally twice daily, or as directed by your doctor. The controlled-release formulation may be prescribed as 60 mg once daily in some cases. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and clinical response. Do not adjust the dose without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dizziness and movement disorders. Dose adjustment may be necessary based on renal function. Regular monitoring is advised.
Renal ImpairmentIn patients with moderate renal impairment (creatinine clearance 30-60 mL/min), dose reduction may be considered. This medicine is contraindicated in severe renal impairment (creatinine clearance <30 mL/min). Consult your doctor for personalized dosing.
Hepatic ImpairmentNo specific dose adjustment is established for patients with hepatic impairment. Use with caution and monitor liver function. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 120 mg, but the usual maximum is 60 mg twice daily. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels and side effects.
Alcohol
Avoid or limit
May increase dizziness and low blood pressure.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of isvedon 60mg tablet cr

✅ Common Side Effects

Dizziness (Common (1-10%))
Avoid driving or operating machinery until you know how it affects you. If dizziness persists, consult your doctor.
Headache (Common (1-10%))
Usually resolves on its own. Rest and hydration may help. Consult doctor if severe or persistent.
Stomach pain (Common (1-10%))
Take with food to reduce discomfort. If pain is severe or persistent, consult your doctor.
Diarrhea (Common (1-10%))
Stay hydrated. Avoid fatty or spicy foods. Consult doctor if diarrhea persists beyond 2 days.
Indigestion (Common (1-10%))
Take with meals. Avoid lying down immediately after eating. Consult doctor if symptoms worsen.
Nausea (Common (1-10%))
Take with food. Eat small, frequent meals. Consult doctor if nausea is severe or persistent.
Vomiting (Common (1-10%))
Stay hydrated with oral rehydration solutions. Consult doctor if vomiting is severe or prevents keeping the medicine down.

🚨 Serious Side Effects

Parkinsonian symptoms (tremor, rigidity, slow movement, difficulty walking) (Rare (<0.1%))
Stop the medicine and seek immediate medical attention. Your doctor may need to adjust or discontinue treatment.
Restless legs syndrome (Rare (<0.1%))
Report to your doctor if you experience an uncontrollable urge to move your legs, especially at night.
Falls (Rare (<0.1%))
Be cautious when standing up or walking, especially if you feel dizzy. Report any falls to your doctor.
Low blood pressure (hypotension) (Rare (<0.1%))
If you feel faint, lightheaded, or have blurred vision, sit or lie down and seek medical help.
Severe allergic reaction (anaphylaxis) (Very rare (<0.01%))
Seek emergency medical care immediately if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.

⚠️ Rare Side Effects

Agranulocytosis
Report any signs of infection such as fever, sore throat, or mouth ulcers immediately.
Thrombocytopenia
Report unusual bruising or bleeding to your doctor.
Hepatitis
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Nitrates Moderate
Beta-blockers Moderate
Calcium channel blockers Moderate
MAOIs Major
CYP3A4 inhibitors Moderate
CYP3A4 inducers Moderate
Antacids Minor

🚨 Major Interactions

  • Other anti-anginal medicines (e.g., nitrates, beta-blockers, calcium channel blockers)
  • Monoamine oxidase inhibitors (MAOIs)

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • CYP3A4 inducers (e.g., rifampicin, carbamazepine)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, low blood pressure, and fainting while taking this medicine. It is advisable to avoid or limit alcohol consumption. Consult your doctor for personalized advice.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Trimetazidine or any component of the formulation","Parkinson's disease, parkinsonian symptoms, tremors, restless legs syndrome","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["This medicine is not for immediate relief of acute angina attacks. Keep fast-acting nitrates available.","May cause or worsen parkinsonian symptoms. Discontinue if symptoms occur and consult a neurologist.","Use with caution in elderly patients due to increased risk of falls and movement disorders.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with mild to moderate renal impairment; dose adjustment may be needed.","Inform your doctor if you have a history of low blood pressure or are taking antihypertensive medicines.","Do not stop this medicine abruptly without medical advice."]

🤱 Lactation Safety

Not established from the available information. It is not known whether this medicine is excreted in human breast milk. Breastfeeding women should consult their doctor before using this medicine.

💊 Overdose Management

There is limited information on overdose with this medicine. In case of suspected overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Monitor vital signs and provide appropriate care. Dialysis is unlikely to be effective due to high protein binding.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water; do not crush, chew, or break it because it is a controlled-release formulation. You may take it with or without food, but taking it with food may reduce stomach upset. Do not stop taking this medicine suddenly without consulting your doctor, as this may worsen your angina. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause dizziness. Inform your doctor if you have kidney problems, liver problems, or a history of Parkinson's disease. Do not use this medicine to treat an acute angina attack; keep your fast-acting nitrate medicine available for that purpose. Tell your doctor about all other medicines you are taking, especially other anti-anginal drugs. Pregnant or breastfeeding women should consult their doctor before using this medicine. Store this medicine at room temperature, away from moisture and direct sunlight, and keep it out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at increased risk of dizziness, falls, and parkinsonian symptoms. Dose adjustment may be needed based on renal function. Regular monitoring of neurological symptoms and kidney function is advised. Caution should be taken when standing up to avoid falls.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. The safety of this medicine in pregnancy is not established. Your doctor will weigh the potential benefits and risks.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be temporarily stopped or adjusted. Follow your doctor's instructions regarding when to resume.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are established, but it is important for your dental care team to know your complete medication list.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce the workload on your heart.
🥗
Engage in regular low-impact exercise like walking or swimming, as advised by your doctor.
😴
Follow a heart-healthy diet rich in fruits, vegetables, and whole grains.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep to support heart health.
🚭
Monitor your blood pressure and cholesterol regularly.

🏋️ Exercise Considerations

This medicine may cause dizziness or low blood pressure, which can affect your ability to exercise safely. Avoid strenuous activities until you know how the medicine affects you. Always warm up and cool down. If you experience chest pain, dizziness, or shortness of breath during exercise, stop and seek medical advice.

🥗 Diet Recommendations

Include omega-3 rich foods like fish, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Eat plenty of fruits and vegetables.
Choose whole grains over refined grains.
Limit salt and sugar intake.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Most people can continue their normal work activities with caution. Inform your employer if your job involves operating heavy machinery.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects such as parkinsonian symptoms, severe dizziness, or allergic reactions, contact your doctor immediately. Your doctor will decide whether to adjust the dose or switch to another medicine.

📅 Long-Term Use Effects

Long-term use of this medicine is generally well-tolerated. However, rare cases of parkinsonian symptoms, restless legs syndrome, and falls have been reported, especially in elderly patients. Regular monitoring of renal function, liver function, and neurological symptoms is advised. Periodic review with your doctor is necessary to assess continued benefit and adjust treatment as needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Heart-healthy diet, regular exercise, smoking cessation, and stress management can complement medicine for angina.

Evidence: Well-established
Cardiac rehabilitation

Supervised exercise and education programs can improve cardiovascular health.

Evidence: Well-established
Revascularization procedures

Angioplasty or bypass surgery may be considered for severe coronary artery disease.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep out of reach of children

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, consult your doctor about adjusting dosing times. Check local customs regulations for carrying prescription medicines. Carry enough supply for your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man with stable angina not fully controlled by beta-blockers
He was prescribed this medicine as add-on therapy. After 4 weeks, he noticed fewer angina attacks during his morning walks. He took it with breakfast as advised and experienced only mild dizziness initially, which resolved. He continues regular follow-ups.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 65-year-old woman with angina and mild kidney impairment
She started this medicine and initially felt dizzy. Her doctor adjusted the dose based on her kidney function. She was advised to rise slowly from sitting or lying positions. Her symptoms improved without further dizziness.
💡 Lesson: Dose adjustment in kidney impairment and slow position changes can prevent dizziness.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine may take several days to weeks to show its full effect. It is not for immediate relief of acute angina attacks.

Q: Can I take this medicine with other heart medicines?

A: It is often prescribed with other heart medicines, but interactions can occur. Always inform your doctor about all medicines you take.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Can I stop taking this medicine suddenly?

A: No, do not stop this medicine without consulting your doctor. Stopping suddenly may worsen your angina.

Q: Does this medicine cause Parkinson's disease?

A: This medicine can cause or worsen parkinsonian symptoms in rare cases. If you experience tremors, stiffness, or difficulty walking, contact your doctor immediately.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Does it cause Parkinson's disease?
  • Is it safe in pregnancy?

🔄 Substitutes for isvedon 60mg tablet cr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for immediate relief of chest pain.
    Fact: This medicine is not for acute angina attacks. It is used for long-term prevention and management. Keep fast-acting nitrates for acute attacks.
  • Myth: This medicine is safe for everyone with heart disease.
    Fact: It is contraindicated in people with Parkinson's disease, parkinsonian symptoms, restless legs syndrome, and severe kidney problems.
  • Myth: You can stop this medicine once you feel better.
    Fact: Do not stop this medicine without consulting your doctor. Stopping suddenly may worsen angina.
  • Myth: This medicine is a blood thinner.
    Fact: This medicine is not a blood thinner. It works by improving heart muscle energy metabolism.

🔄 Alternative Options

Generic Alternatives

  • Trimetazidine 60 mg controlled-release tablet

Brand Alternatives

  • Isvedon 60 mg Tablet CR

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Trimetazidine)","class":"Metabolic anti-ischemic agent","primary_use":"Add-on therapy for stable angina","mechanism":"Shifts energy metabolism to glucose oxidation","common_side_effects":"Dizziness, headache, stomach pain"},{"medicine":"Ranolazine","class":"Late sodium current inhibitor","primary_use":"Chronic stable angina","mechanism":"Reduces intracellular sodium and calcium overload","common_side_effects":"Dizziness, constipation, nausea"},{"medicine":"Ivabradine","class":"If channel blocker","primary_use":"Stable angina, heart failure","mechanism":"Reduces heart rate","common_side_effects":"Bradycardia, visual disturbances"}]

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