cynocal injection - Thiamine(Vitamin B1) (100mg) + Vitamin B6 (Pyridoxine) (1mg) medicine

cynocal injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Ozone Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is cynocal injection used for?

Aneudox 12 Forte Injection (Thiamine + Pyridoxine) is used to treat VITAMINS MINERALS NUTRIENTS. It contains Thiamine(Vitamin B1) (100mg) + Vitamin B6 (Pyridoxine) (1mg), which Thiamine acts as a coenzyme in carbohydrate metabolism; Pyridoxine is a cofactor. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Thiamine + Pyridoxine
  • Manufacturer: Ozone Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š cynocal injection Uses & Benefits

Treatment and prevention of vitamin B1 and B6 deficiencies; peripheral neuropathy; neuritis; beriberi; Wernicke-Korsakoff syndrome; adjunct in alcoholism

Off-label uses: Diabetic neuropathy, Alzheimer's disease, Pain management

๐Ÿ“‹ Drug Information

Generic Name(s)Thiamine + Pyridoxine
Brand NameAneudox 12 Forte Injection
ManufacturerOzone Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassVitamins
Route of AdministrationIntramuscular injection
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular injection
DistributionWidely distributed; crosses placenta and enters breast milk
Protein BindingThiamine: low; Pyridoxine: ~90% bound to plasma proteins
MetabolismThiamine: metabolized in liver; Pyridoxine: metabolized in liver to active pyridoxal phosphate
Half-LifeThiamine: 9-18 days; Pyridoxine: 15-20 days
ExcretionRenal (urine) as metabolites and unchanged drug
Bioavailability100% (intramuscular)
Onset of ActionRapid (within minutes to hours)
Peak Plasma TimeThiamine: 1-2 hours; Pyridoxine: 0.5-1 hour
Duration of ActionSeveral days to weeks

How It Works

Thiamine acts as a coenzyme in carbohydrate metabolism; Pyridoxine is a cofactor for enzymes involved in amino acid, neurotransmitter, and heme synthesis

Mechanism Steps

1Thiamine is converted to thiamine pyrophosphate (TPP), a coenzyme in carbohydrate metabolism (e.g., pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, transketolase).
2Pyridoxine is converted to pyridoxal phosphate (PLP), a cofactor for transamination, decarboxylation, and other reactions in amino acid and neurotransmitter synthesis.

๐Ÿ’ก How to Take cynocal injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cynocal injection

โœ… Common Side Effects

  • Pain at injection site
  • Nausea
  • Headache
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Allergic reactions (anaphylaxis)
  • Peripheral neuropathy (with high doses of pyridoxine)

โš ๏ธ Rare Side Effects

  • Seizures
  • Photosensitivity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Levodopa Major Pyridoxine reduces levodopa efficacy
Cycloserine Major Increased risk of peripheral neuropathy
Isoniazid Major Pyridoxine deficiency exacerbated
Penicillamine Major Pyridoxine deficiency
Hydralazine Major Pyridoxine deficiency
Oral contraceptives Moderate Decreased pyridoxine levels
Loop diuretics Moderate Increased thiamine excretion
Alcohol Moderate Reduced thiamine and pyridoxine levels
Tetracyclines Minor Decreased tetracycline absorption
Phenytoin Minor Decreased phenytoin levels

๐Ÿšจ Major Interactions

  • Levodopa
  • Cycloserine
  • Isoniazid
  • Penicillamine
  • Hydralazine

โšก Moderate Interactions

  • Oral contraceptives
  • Loop diuretics
  • Alcohol

โ„น๏ธ Minor Interactions

  • Tetracyclines
  • Phenytoin

๐Ÿฝ๏ธ Food Interactions

None significant

๐Ÿท Alcohol Interaction

Alcohol increases thiamine deficiency and may reduce pyridoxine levels

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component

๐Ÿ“Š Monitoring Parameters

Monitor for signs of deficiency or toxicity; periodic blood levels if long-term use

๐Ÿคฑ Lactation Safety

Safe; excreted in breast milk but not harmful

๐Ÿ’Š Overdose Management

Discontinue use; supportive care; symptoms may include nausea, vomiting, headache, and allergic reactions

โฐ Missed Dose

Administer as soon as remembered; if near next dose, skip missed dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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