cylenc ds 250mg tablet - Uses, Price, Side Effects & Substitutes
What is cylenc ds 250mg tablet used for?
Alporate D 500mg Tablet ER (Divalproex) is used to treat NEURO CNS. It contains Divalproex (250mg), which Increases GABA levels by inhibiting GABA transaminase and enhancing GABA synthes. Always consult your doctor before use. Take as prescribed.
- Generic Name: Divalproex
- Manufacturer: D.S. Lab
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cylenc ds 250mg tablet Uses & Benefits
Epilepsy (complex partial, absence, generalized tonic-clonic), bipolar disorder (mania), migraine prophylaxis.
Off-label uses: Neuropathic pain, status epilepticus (IV), agitation in dementia, schizophrenia augmentation.
๐ Drug Information
| Generic Name(s) | Divalproex |
| Brand Name | Alporate D 500mg Tablet ER |
| Manufacturer | D.S. Lab |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Sodium channel modulators (AED) |
| Route of Administration | Oral (extended-release tablet). |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Increases GABA levels by inhibiting GABA transaminase and enhancing GABA synthesis; also blocks voltage-gated sodium channels and T-type calcium channels.
Mechanism Steps
๐ก How to Take cylenc ds 250mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cylenc ds 250mg tablet
โ Common Side Effects
- Nausea
- vomiting
- dizziness
- somnolence
- tremor
- weight gain
- thrombocytopenia
- alopecia
- asthenia
๐จ Serious Side Effects
- Hepatotoxicity
- pancreatitis
- hyperammonemic encephalopathy
- teratogenicity
- bone marrow suppression
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Fanconi syndrome
- polycystic ovary syndrome
- hypothyroidism
- vasculitis
- lupus-like syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Carbamazepine | Major | Decreased valproate levels; increased carbamazepine toxicity |
| Lamotrigine | Major | Increased lamotrigine levels; risk of Stevens-Johnson syndrome |
| Phenytoin | Major | Altered phenytoin levels; increased valproate toxicity |
| Phenobarbital | Major | Increased phenobarbital levels; sedation |
| Rifampin | Major | Decreased valproate levels |
| Topiramate | Major | Increased risk of hyperammonemia |
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Moderate | Increased valproate levels; bleeding risk |
| Cimetidine | Moderate | Increased valproate levels |
| Erythromycin | Moderate | Increased valproate levels |
| Felbamate | Moderate | Increased valproate levels |
| Fluoxetine | Moderate | Increased valproate levels |
| Ibuprofen | Moderate | Increased valproate levels; bleeding risk |
| Olanzapine | Moderate | Increased valproate levels |
| Risperidone | Moderate | Increased valproate levels |
| Tricyclic antidepressants | Moderate | Increased CNS depression |
| Acetaminophen | Minor | Possible increased hepatotoxicity |
| Antacids | Minor | Decreased valproate absorption |
| Cholestyramine | Minor | Decreased valproate absorption |
| Oral contraceptives | Minor | Decreased contraceptive efficacy |
๐จ Major Interactions
- Carbamazepine
- Lamotrigine
- Phenytoin
- Phenobarbital
- Rifampin
- Topiramate
- Warfarin
โก Moderate Interactions
- Aspirin
- Cimetidine
- Erythromycin
- Felbamate
- Fluoxetine
- Ibuprofen
- Olanzapine
- Risperidone
- Tricyclic antidepressants
โน๏ธ Minor Interactions
- Acetaminophen
- Antacids
- Cholestyramine
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Food may delay absorption but not extent; avoid grapefruit juice (may increase levels).
๐ท Alcohol Interaction
Avoid alcohol; increases CNS depression and hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, hepatic disease, urea cycle disorders, mitochondrial disorders, porphyria, pregnancy (for migraine prophylaxis).
๐ Monitoring Parameters
Liver function tests, CBC, serum valproate levels (therapeutic: 50-100 mcg/mL), ammonia levels, coagulation parameters.
๐คฑ Lactation Safety
Excreted in breast milk; caution advised (risk of hepatotoxicity in infant).
๐ Overdose Management
Supportive care; activated charcoal if early; hemodialysis may be effective; monitor for CNS depression, respiratory depression, and hepatic failure.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cylenc ds 250mg tablet
View AllAlternative brands with exact same active ingredient (Divalproex (250mg)):
-
esdival 250mg tablet erEsteem Pharmaceuticals โน22.50 31.4% CHEAPER
-
diavox 250mg tabletPsycogen Captab โน23.44 28.6% CHEAPER
-
davaindia divalproex 250mg tablet erDavaindia Generic Pharmacy โน24.00 26.9% CHEAPER
-
kayval 250mg tabletSolitaire Pharmacia Pvt Ltd โน24.00 26.9% CHEAPER
-
diproex 250mg tabletTorrent Pharmaceuticals Ltd โน32.91 0.3% COSTLIER
-
divalop 250mg tabletRKG Pharma โน35.63 8.6% COSTLIER
-
di elival 250mg tablet erElite Pharma Pvt Ltd โน35.63 8.6% COSTLIER
-
dval 250mg tabletBaroda Pharma Pvt Ltd โน36.53 11.3% COSTLIER
-
disokind 250 mg tablet erMankind Pharma Ltd โน36.56 11.4% COSTLIER
-
disorate 250 mg tabletMankind Pharma Ltd โน36.56 11.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.