cure depot 250mg injection - Hydroxyprogesterone (250mg) medicine

Anin 250 Injection: Complete Medicine Guide

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🏭 Mancure Drugs Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
🤰 Pregnancy Category Not applicable; hydroxyprogesterone is used in pregnancy under medical supervision. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Limited to moderate
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden shortness of breath or chest pain
  • Swelling or pain in one leg
  • Severe headache with vision changes
  • Yellowing of skin or eyes
  • Severe allergic reaction (rash, swelling, difficulty breathing)

If experiencing severe symptoms, call emergency services immediately.

What is cure depot 250mg injection used for?

This medicine is a hydroxyprogesterone injection used in women's health to support pregnancy and regulate menstrual cycles. It is given intramuscularly by a healthcare professional.

  • Generic Name: Hydroxyprogesterone
  • Manufacturer: Mancure Drugs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cure depot 250mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा हाइड्रॉक्सीप्रोजेस्टेरोन का इंजेक्शन है, जिसका उपयोग महिलाओं में प्रोजेस्टेरोन की कमी से जुड़ी समस्याओं के इलाज के लिए किया जाता है। यह गर्भावस्था को सहारा देने, मासिक धर्म को नियमित करने और प्रजनन उपचार में मदद करती है। यह इंजेक्शन डॉक्टर द्वारा मांसपेशी में लगाया जाता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, सूजन, सिरदर्द, मतली, और स्तन में कोमलता शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन खून के थक्के, एलर्जी, और मूड में बदलाव हो सकते हैं। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल डॉक्टर या स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। खुद से इंजेक्शन न लगाएं। गर्भवती, स्तनपान कराने वाली महिलाएं और अन्य दवाएं लेने वाले मरीज डॉक्टर को जरूर बताएं। शराब से बचें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 cure depot 250mg injection Uses & Benefits

[{"condition":"Threatened miscarriage","description":"Used to support early pregnancy when progesterone levels are low, helping to maintain the pregnancy.","evidence":"Limited"},{"condition":"Luteal phase support in assisted reproduction","description":"Given to support the uterine lining after ovulation induction or embryo transfer.","evidence":"Well-established"},{"condition":"Menstrual disorders","description":"Helps regulate abnormal uterine bleeding due to hormonal imbalance.","evidence":"Limited"}]

Off-label uses: [{"condition":"Preterm birth prevention","description":"Sometimes used off-label to prevent preterm labor in women with a history of preterm birth.","evidence":"Limited"}]

Primary treatment for: Progesterone deficiency

Also treats: Threatened miscarriage, Luteal phase defect

📋 Drug Information

Generic Name(s)Hydroxyprogesterone
Brand NameAnin 500mg Injection
ManufacturerMancure Drugs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassProgestins (First generation)
Route of AdministrationIntramuscular
StorageStore at room temperature (15-30°C). Protect from light. Do not freeze.
Shelf LifeNot established from the available information.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer strictly as prescribed by a healthcare professional.
2
Monitor for signs of blood clots such as leg pain or swelling.
3
Assess liver function periodically during long-term use.
4
Advise patient to report any unusual vaginal bleeding.
5
Use with caution in patients with a history of depression.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Threatened miscarriage
This medicine may be prescribed to support early pregnancy.
Likely Use
✅
Irregular menstrual bleeding
This medicine can help regulate menstrual cycles.
Likely Use
❌
Fever
This medicine is not used to treat fever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAbsorbed slowly from the intramuscular injection site.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismMetabolized in the liver, primarily by reduction and conjugation.
Half-LifeNot established from the available information.
ExcretionExcreted mainly in urine as metabolites.
BioavailabilityNot established from the available information.
Onset of ActionNot established from the available information.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

This medicine works by binding to progesterone receptors in target tissues such as the uterus, breasts, and brain. This binding mimics the natural hormone progesterone, leading to changes in gene expression that support the menstrual cycle, maintain pregnancy, and regulate uterine contractions.

Mechanism Steps

1
Binding to progesterone receptor: This medicine binds to progesterone receptors in the cytoplasm of target cells.
2
Receptor activation: The drug-receptor complex moves into the nucleus and binds to DNA response elements.
3
Gene transcription: This alters the transcription of specific genes, leading to the production of proteins that mediate progesterone effects.
4
Physiological effects: The result is maintenance of the endometrium, support of pregnancy, and regulation of the menstrual cycle.

💡 How to Take cure depot 250mg injection

Strength: 250 mg injection

1This medicine is given by a healthcare professional as an intramuscular injection.
2It is usually injected into the gluteal muscle.
3Do not self-administer.
4Follow your doctor's schedule for injections.

Dosage Information

Adult DosageThe dose is individualized by a qualified clinician based on the indication, age, weight, and clinical response. It is given as an intramuscular injection by a healthcare professional. Do not self-administer.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustments are established. Use with caution and monitor for side effects.
Renal ImpairmentNot established from the available information. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose adjustment may be needed.
Maximum Daily DoseNot established from the available information.

⏰ What to Do If You Miss a Dose

📌 If you miss a scheduled injection
→ Contact your doctor as soon as possible to reschedule.
💡 Do not attempt to self-administer a double dose.

⚠️ Side Effects of cure depot 250mg injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold pack to the area. It usually resolves within a day.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe.
Nausea (Common (5-10%))
Take with food if possible. Consult doctor if persistent.
Breast tenderness (Common (5-10%))
Wear a supportive bra. Consult doctor if severe.

🚨 Serious Side Effects

Blood clots (Rare (<0.1%))
Seek immediate medical attention if you notice leg swelling, chest pain, or shortness of breath.
Severe allergic reaction (Rare (<0.1%))
Call emergency services if you experience rash, itching, swelling of face or throat, or difficulty breathing.

⚠️ Rare Side Effects

Jaundice
Report yellowing of skin or eyes to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Rifampicin Moderate

🚨 Major Interactions

  • Warfarin

⚡ Moderate Interactions

  • Rifampicin

🍷 Alcohol Interaction

Avoid alcohol as it may worsen side effects such as dizziness and nausea.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to hydroxyprogesterone or any ingredient","Undiagnosed vaginal bleeding","Known or suspected breast cancer","History of blood clots (thrombophlebitis, pulmonary embolism)","Severe liver disease"]

⚠️ Warnings & Precautions

["Use with caution in patients with a history of depression.","May cause fluid retention; caution in heart or kidney disease.","May affect blood sugar levels; monitor in diabetics.","Not for use in men or children unless prescribed by a specialist.","Inform your doctor if you are breastfeeding."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose is unlikely due to intramuscular administration by a healthcare professional. If overdose is suspected, seek immediate medical attention. Treatment is symptomatic and supportive.

⏰ Missed Dose

If you miss a dose, contact your doctor for advice. Do not double the dose.

Additional Safety Advice

General Safety

This medicine must be given by a healthcare professional only. Do not self-administer. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Tell your doctor about all medicines you take, especially blood thinners. Avoid alcohol during treatment. Report any unusual symptoms immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to side effects. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. It may be prescribed as part of fertility treatment.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine, as it may affect blood clotting.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, especially before any surgical dental work.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight.
🥗
Stay physically active as advised by your doctor.
😴
Avoid smoking as it increases clot risk.
💧
Limit alcohol consumption.
🧘
Get adequate rest.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience dizziness or fatigue. Consult your doctor before starting any new exercise routine.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Stay well hydrated.
Limit salt intake to reduce fluid retention.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Your doctor will determine the appropriate duration of treatment.

📅 Long-Term Use Effects

Long-term use may increase the risk of blood clots, liver problems, and fluid retention. Regular monitoring by a doctor is recommended.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral progesterone

Alternative dosage form for progesterone support.

Evidence: Well-established
Vaginal progesterone

Another route for progesterone administration.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. Consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in a cool, dry place away from direct sunlight. If traveling across time zones, consult your doctor about adjusting the timing of injections. Declare it at customs if required.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with a history of recurrent miscarriage
She was prescribed this medicine as part of her treatment to support early pregnancy. She received weekly injections under medical supervision and successfully carried her pregnancy to term. She reported mild injection site pain but no other significant side effects.
💡 Lesson: Regular medical supervision and adherence to the prescribed schedule are crucial for successful outcomes.
👤 A 28-year-old woman undergoing IVF treatment
She received this medicine for luteal phase support after embryo transfer. The injections were given by a nurse. She experienced some breast tenderness and mood swings but these were manageable. She emphasized the importance of following the clinic's protocol.
💡 Lesson: Communicate any side effects to your fertility specialist; they can help manage symptoms.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The effects vary depending on the indication. Your doctor will monitor your response.

Q: Is this injection painful?

A: There may be some discomfort at the injection site, but it is usually mild and temporary.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my fertility?
  • Can I drive after taking this medicine?
  • Does it interact with my other medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cure depot 250mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be self-administered at home.
    Fact: It must be given by a healthcare professional.
  • Myth: This medicine is safe for everyone.
    Fact: It is contraindicated in certain conditions like breast cancer and blood clots.

📊 Comparison with Similar Medicines

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