cugine 50mg tablet dt - Uses, Price, Side Effects & Substitutes
What is cugine 50mg tablet dt used for?
Cugine (Lamotrigine) is used to treat NEURO CNS. It contains Lamotrigine (50mg), which Stabilizes neuronal membranes by inhibiting voltage-sensitive sodium channels, t. Always consult your doctor before use. Take as prescribed.
- Generic Name: Lamotrigine
- Manufacturer: Cubit Healthcare
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ cugine 50mg tablet dt Uses & Benefits
Epilepsy (partial and generalized seizures), Bipolar I disorder (maintenance therapy).
Off-label uses: Neuropathic pain, migraine prophylaxis, schizophrenia (adjunctive), post-traumatic stress disorder.
๐ Drug Information
| Generic Name(s) | Lamotrigine |
| Brand Name | Cugine |
| Manufacturer | Cubit Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Sodium channel modulators (AED) |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Stabilizes neuronal membranes by inhibiting voltage-sensitive sodium channels, thereby inhibiting the release of excitatory neurotransmitters (e.g., glutamate).
Mechanism Steps
๐ก How to Take cugine 50mg tablet dt
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cugine 50mg tablet dt
โ Common Side Effects
- Dizziness
- Headache
- Diplopia
- Blurred vision
- Nausea
- Vomiting
- Ataxia
- Somnolence
- Insomnia
- Tremor
- Rash
๐จ Serious Side Effects
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- DRESS syndrome
- Hemophagocytic lymphohistiocytosis
- Aseptic meningitis
- Blood dyscrasias
- Suicidal thoughts or behavior
โ ๏ธ Rare Side Effects
- Hepatic failure
- Pancreatitis
- Lupus-like syndrome
- Angioedema
- Photosensitivity
- Multiorgan hypersensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Valproate | Major | Increased lamotrigine levels; risk of Stevens-Johnson syndrome; reduce lamotrigine dose. |
| Carbamazepine | Major | Decreased lamotrigine levels; reduced efficacy; may need dose adjustment. |
| Phenytoin | Major | Decreased lamotrigine levels; reduced efficacy. |
| Phenobarbital | Major | Decreased lamotrigine levels; reduced efficacy. |
| Primidone | Major | Decreased lamotrigine levels; reduced efficacy. |
| Rifampin | Major | Decreased lamotrigine levels; reduced efficacy. |
| Lopinavir/ritonavir | Major | Decreased lamotrigine levels; reduced efficacy. |
| Oral contraceptives | Moderate | Decreased lamotrigine levels; reduced efficacy; may need dose adjustment. |
| Ethinylestradiol | Moderate | Decreased lamotrigine levels. |
| Levonorgestrel | Moderate | Decreased lamotrigine levels. |
| Atazanavir/ritonavir | Moderate | Decreased lamotrigine levels. |
| Sertraline | Moderate | Possible increased lamotrigine levels. |
| Bupropion | Moderate | Possible increased seizure risk. |
| Acetaminophen | Minor | Possible decreased lamotrigine levels. |
| Folate | Minor | Possible decreased lamotrigine levels. |
| Lithium | Minor | Possible additive CNS effects. |
๐จ Major Interactions
- Valproate
- Carbamazepine
- Phenytoin
- Phenobarbital
- Primidone
- Rifampin
- Lopinavir/ritonavir
โก Moderate Interactions
- Oral contraceptives
- Ethinylestradiol
- Levonorgestrel
- Atazanavir/ritonavir
- Sertraline
- Bupropion
โน๏ธ Minor Interactions
- Acetaminophen
- Folate
- Lithium
๐ฝ๏ธ Food Interactions
No significant food interactions; may be taken with or without food.
๐ท Alcohol Interaction
Avoid alcohol; may increase CNS depression and seizure risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to lamotrigine or any component of the formulation.
๐ Monitoring Parameters
Serum lamotrigine levels (therapeutic range 2.5-15 mcg/mL), hepatic function, renal function, CBC, signs of rash (Stevens-Johnson syndrome).
๐คฑ Lactation Safety
Limited data; use with caution; monitor infant for adverse effects.
๐ Overdose Management
Supportive care; activated charcoal may be considered; monitor for CNS depression, ataxia, nystagmus, seizures, coma.
โฐ Missed Dose
Take as soon as remembered unless close to next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cugine 50mg tablet dt
View AllAlternative brands with exact same active ingredient (Lamotrigine (50mg)):
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lamolet 50mg tablet dtZeelab Pharmacy Pvt Ltd โน10.00 87.3% CHEAPER
-
davaindia lamotrigine 50mg tablet dtDavaindia Generic Pharmacy โน12.00 84.7% CHEAPER
-
lamogin 50mg tablet dtFDC Ltd โน38.41 51.2% CHEAPER
-
lamoz 50mg tabletAlkem Laboratories Ltd โน51.28 34.8% CHEAPER
-
epilam 50mg tablet dtReliance Formulation Pvt Ltd โน51.42 34.6% CHEAPER
-
laogine 50mg tabletEsteem Pharmaceuticals โน53.00 32.6% CHEAPER
-
ictalam 50mg tabletGlenmark Pharmaceuticals Ltd โน53.08 32.5% CHEAPER
-
FAVLAM 50 MG TABLETUSV Ltd โน54.85 30.3% CHEAPER
-
lamorig 50mg tabletTorrent Pharmaceuticals Ltd โน56.72 27.9% CHEAPER
-
lyzin 50mg tabletPifer Pharmaceuticals Pvt Ltd โน60.00 23.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.