cufrio ls syrup - Ambroxol (30mg) + Levosalbutamol (1mg) medicine

cufrio ls syrup - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Riomedica Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is cufrio ls syrup used for?

Ascoril LS Junior Syrup (Ambroxol + Levosalbutamol) is used to treat RESPIRATORY. It contains Ambroxol (30mg) + Levosalbutamol (1mg), which Ambroxol increases mucus clearance by stimulating surfactant production and redu. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ambroxol + Levosalbutamol
  • Manufacturer: Riomedica Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š cufrio ls syrup Uses & Benefits

Acute and chronic bronchitis, Asthma, COPD, Bronchiectasis

๐Ÿ“‹ Drug Information

Generic Name(s)Ambroxol + Levosalbutamol
Brand NameAscoril LS Junior Syrup
ManufacturerRiomedica Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Beta-2 Adrenergic Agonist
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract
DistributionWidely distributed; crosses placenta and enters breast milk
Protein BindingAmbroxol: ~90%; Levosalbutamol: ~50%
MetabolismAmbroxol: Hepatic (glucuronidation); Levosalbutamol: Hepatic (sulfation)
Half-LifeAmbroxol: 7-12 hours; Levosalbutamol: 3-4 hours
ExcretionAmbroxol: Renal (90%); Levosalbutamol: Renal (60-70%)
BioavailabilityAmbroxol: ~70%; Levosalbutamol: ~50%
Onset of ActionAmbroxol: 30-60 min; Levosalbutamol: 15-30 min
Peak Plasma TimeAmbroxol: 1-2 hours; Levosalbutamol: 1-2 hours
Duration of ActionAmbroxol: 6-12 hours; Levosalbutamol: 4-6 hours

How It Works

Ambroxol increases mucus clearance by stimulating surfactant production and reducing mucus viscosity; Levosalbutamol selectively stimulates beta-2 adrenergic receptors, causing bronchodilation.

Mechanism Steps

1Ambroxol stimulates type II pneumocytes to increase surfactant production.
2Ambroxol reduces mucus viscosity by breaking disulfide bonds in mucoproteins.
3Levosalbutamol binds to beta-2 adrenergic receptors on bronchial smooth muscle.

๐Ÿ’ก How to Take cufrio ls syrup

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cufrio ls syrup

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Tremor
  • Palpitations

๐Ÿšจ Serious Side Effects

  • Hypokalemia
  • Cardiac arrhythmias
  • Paradoxical bronchospasm
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Nephrotoxicity
  • Severe skin reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Minor
Minor
Minor

๐Ÿšจ Major Interactions

  • MAOIs
  • Tricyclic antidepressants
  • Beta-blockers

โšก Moderate Interactions

  • Diuretics
  • Corticosteroids
  • Xanthine derivatives

โ„น๏ธ Minor Interactions

  • Anticholinergics
  • Other sympathomimetics

๐Ÿฝ๏ธ Food Interactions

No significant interactions

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase sedation or hepatotoxicity risk.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, Cardiac arrhythmias, Hypertension, Hyperthyroidism, Diabetes mellitus

๐Ÿ“Š Monitoring Parameters

LFT, RFT, CBC, Serum electrolytes, Heart rate, Blood pressure

๐Ÿคฑ Lactation Safety

Caution; excreted in breast milk, use only if clearly needed.

๐Ÿ’Š Overdose Management

Symptomatic and supportive; monitor cardiac function, electrolytes; consider activated charcoal if recent ingestion.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

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