crotol hc cream - Hydrocortisone (0.25% w/w) + Crotamiton (10% w/w) medicine

Crotorax HC Cream: Comprehensive Guide to Uses, Dosage, and Safety

No reviews yet
🏭 Canbro Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hydrocortisone and crotamiton individually; combination evidence is based on established use.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of the face, lips, or throat, or difficulty breathing.
  • Signs of skin infection such as increased redness, swelling, pus, or pain.
  • Vision changes or eye pain if the cream accidentally gets into the eyes.
  • Symptoms of systemic corticosteroid effects like rapid weight gain, moon face, or easy bruising.
  • No improvement or worsening of the condition after 7 days of use.
  • Severe burning, itching, or rash that spreads beyond the application site.

If experiencing severe symptoms, call emergency services immediately.

What is crotol hc cream used for?

This medicine is a topical cream containing hydrocortisone 0.25% and crotamiton 10%. It is used to treat itching, inflammation, and scabies. Apply a thin layer to the affected area 2-3 times daily, or as directed by your doctor.

  • Generic Name: Hydrocortisone + Crotamiton
  • Manufacturer: Canbro Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 crotol hc cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें हाइड्रोकॉर्टिसोन 0.25% और क्रोटामिटोन 10% होता है। इसका उपयोग खुजली, सूजन, एक्जिमा, डर्मेटाइटिस, कीड़े के काटने और स्केबीज के इलाज के लिए किया जाता है। यह क्रीम प्रभावित त्वचा पर पतली परत में लगाई जाती है। यह सूजन और खुजली को कम करने में मदद करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर जलन, खुजली, लालिमा या सूखापन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। दुर्लभ मामलों में त्वचा पतली हो सकती है या स्ट्रेच मार्क्स पड़ सकते हैं। गंभीर एलर्जी प्रतिक्रिया होने पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का इस्तेमाल केवल बाहरी त्वचा पर करें। आंखों, मुंह और श्लेष्मा झिल्ली के संपर्क में न आने दें। लगाने से पहले और बाद में हाथ धोएं। बिना डॉक्टर की सलाह के 2 सप्ताह से अधिक इस्तेमाल न करें। अगर 7 दिनों में सुधार न हो तो डॉक्टर से मिलें। बच्चों में 2 साल से कम उम्र में उपयोग न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 crotol hc cream Uses & Benefits

[{"condition":"Eczema","description":"Relieves itching, redness, and inflammation associated with eczema.","evidence":"Well-established"},{"condition":"Contact dermatitis","description":"Reduces inflammation and itching caused by allergic or irritant contact dermatitis.","evidence":"Well-established"},{"condition":"Insect bites","description":"Soothes itching and swelling from insect bites.","evidence":"Well-established"},{"condition":"Scabies","description":"Crotamiton component treats scabies infestation and relieves associated itching.","evidence":"Well-established"},{"condition":"Pruritus","description":"Provides symptomatic relief from itching due to various causes.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Psoriasis","description":"Sometimes used to reduce itching and inflammation in mild psoriasis.","evidence":"Limited"},{"condition":"Lichen simplex chronicus","description":"May be used to relieve itching and inflammation in this condition.","evidence":"Limited"}]

Primary treatment for: Pruritus

Also treats: Eczema, Contact dermatitis, Insect bites, Scabies

📋 Drug Information

Generic Name(s)Hydrocortisone + Crotamiton
Brand NameCrotorax HC Cream
ManufacturerCanbro Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassCorticosteroid + Antipruritic/Scabicide
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from light and moisture. Do not freeze. Keep the tube tightly closed when not in use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin layer of the cream to the affected area and rub it in gently.
2
Wash your hands before and after applying the cream to prevent spreading.
3
Do not use this medicine on the face, groin, or underarms unless your doctor specifically tells you to.
4
Avoid using this medicine for more than 2 weeks without consulting your doctor.
5
If your condition does not improve within 7 days, stop using the cream and consult your doctor.
6
Do not cover the treated area with tight bandages or dressings unless instructed.
7
Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Itching
This medicine is commonly prescribed for itching due to various skin conditions.
Likely Use
✅
Skin redness and inflammation
This medicine helps reduce redness and inflammation.
Likely Use
✅
Scabies infestation
This medicine contains crotamiton, which treats scabies.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Bacterial skin infection
This medicine is not an antibiotic and should not be used on infected skin without medical advice.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionHydrocortisone is absorbed through the skin, especially when applied to large areas, broken skin, or under occlusive dressings. Crotamiton absorption through intact skin is minimal. Systemic absorption of hydrocortisone can occur and may lead to systemic effects with prolonged use.
DistributionOnce absorbed, hydrocortisone is distributed throughout the body, primarily bound to corticosteroid-binding globulin and albumin. Crotamiton distribution is not well established.
Protein BindingHydrocortisone is approximately 90% bound to plasma proteins, mainly corticosteroid-binding globulin and albumin. Protein binding of crotamiton is not established from the available information.
MetabolismHydrocortisone is metabolized in the liver, primarily by reduction and conjugation. Crotamiton metabolism is not well established from the available information.
Half-LifeThe biological half-life of hydrocortisone is approximately 8 to 12 hours. The elimination half-life of crotamiton is not established from the available information.
ExcretionHydrocortisone metabolites are excreted mainly in the urine. Crotamiton excretion is not established from the available information.
BioavailabilityBioavailability of hydrocortisone after topical application varies depending on the skin condition, application site, and use of occlusive dressings. It is generally low but can be significant with damaged skin. Bioavailability of crotamiton is not established from the available information.
Onset of ActionRelief from itching may begin within a few hours to days of application. Anti-inflammatory effects typically become noticeable within 1 to 3 days of regular use.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe duration of action depends on the condition being treated and the frequency of application. Symptomatic relief may last for several hours after each application.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Hydrocortisone is a corticosteroid that binds to glucocorticoid receptors in the skin, leading to suppression of inflammatory mediators such as prostaglandins and leukotrienes, and reduction of immune cell activity. This results in decreased redness, swelling, and itching. Crotamiton is an antipruritic and scabicidal agent whose exact mechanism is not fully understood, but it is believed to act by blocking sensory nerve endings to relieve itching and by interfering with the nervous system of scabies mites, leading to their death.

Mechanism Steps

1
Hydrocortisone binds to glucocorticoid receptors: Hydrocortisone enters skin cells and binds to cytoplasmic glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription.
2
Suppression of inflammatory mediators: This leads to decreased production of inflammatory cytokines, prostaglandins, and leukotrienes, reducing redness, swelling, and itching.
3
Crotamiton relieves itching: Crotamiton acts on sensory nerve endings to reduce the sensation of itch, providing symptomatic relief.
4
Crotamiton kills scabies mites: Crotamiton interferes with the nervous system of scabies mites, leading to their paralysis and death.

💡 How to Take crotol hc cream

Strength: Cream containing hydrocortisone 0.25% w/w and crotamiton 10% w/w.

1Wash your hands thoroughly before and after applying the cream.
2Clean and dry the affected area gently.
3Apply a thin layer of the cream to the affected area.
4Rub it in gently until it is absorbed.
5Do not cover the area with a bandage unless instructed.
6Avoid contact with eyes, mouth, and other mucous membranes.
7Use as directed by your doctor, usually 2 to 3 times daily.

Dosage Information

Adult DosageApply a thin layer to the affected area 2 to 3 times daily, or as directed by your doctor. The frequency and duration of treatment depend on the condition being treated and your response to therapy. For scabies, apply from the neck down to the toes, leave on for 24 hours, and wash off. Repeat after 24 hours. Dose must be individualized by a qualified clinician based on indication, age, and skin condition.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 2 years of age.
Elderly DosageElderly patients may be more susceptible to the effects of corticosteroids. Use the lowest effective dose for the shortest duration. Consult a doctor for individualized dosing.
Renal ImpairmentNo specific dosage adjustment is established for renal impairment. Use with caution due to potential systemic absorption.
Hepatic ImpairmentNo specific dosage adjustment is established for hepatic impairment. Use with caution due to potential systemic absorption.
Maximum Daily DoseNot established from the available information. Use only as directed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 If you miss a dose and remember within a few hours
→ Apply the missed dose as soon as you remember.
💡 Continue with your regular schedule.
📌 If it is almost time for your next dose
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of crotol hc cream

✅ Common Side Effects

Application site burning (Common (1-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Application site itching (Common (1-10%))
May be due to the condition or the medicine. Consult your doctor if it worsens.
Skin dryness (Common (1-10%))
Use a moisturizer if needed. Consult your doctor if it persists.
Redness or rash (Common (1-10%))
Stop using and consult your doctor if it spreads or worsens.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, throat, or difficulty breathing.
Skin thinning and stretch marks (Uncommon (0.1-1%))
Avoid prolonged use on the same area. Consult your doctor if you notice skin changes.
Adrenal suppression (Rare (<0.1%))
Prolonged use over large areas can cause this. Consult your doctor if you experience fatigue, weakness, or weight loss.
Secondary skin infection (Uncommon (0.1-1%))
Consult your doctor if you notice increased redness, swelling, or pus.

⚠️ Rare Side Effects

Cushing's syndrome
Seek medical advice if you experience rapid weight gain, moon face, or easy bruising.
Hyperglycemia
Monitor blood sugar if you are diabetic. Consult your doctor if levels rise.
Glaucoma or increased intraocular pressure
Avoid application near eyes. Consult an eye doctor if you notice vision changes.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole (topical) Moderate
Ritonavir Major
Insulin Moderate
Warfarin Moderate

🚨 Major Interactions

  • Other topical corticosteroids
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

  • Antidiabetic drugs
  • Diuretics

🍷 Alcohol Interaction

No known interaction between this topical medicine and alcohol. However, alcohol may worsen certain skin conditions and should be consumed in moderation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to hydrocortisone, crotamiton, or any component of the cream.","Untreated bacterial, viral, or fungal skin infections.","Acne vulgaris, rosacea, and perioral dermatitis.","Use on the face, groin, or axillae unless directed by a doctor.","Use in children under 2 years of age.","Use on large areas of broken skin or under occlusive dressings."]

⚠️ Warnings & Precautions

["For external use only. Avoid contact with eyes, mouth, and mucous membranes.","Do not use on open wounds or infected skin unless prescribed.","Prolonged use can lead to skin thinning, stretch marks, and systemic absorption.","Do not use for more than 2 weeks without medical advice.","If symptoms persist or worsen after 7 days, consult a doctor.","Use with caution in pregnant and breastfeeding women.","Keep out of reach of children.","Do not use if the tube is damaged or the cream has changed color."]

🤱 Lactation Safety

It is not known whether hydrocortisone or crotamiton are excreted in human milk after topical application. Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. Because many drugs are excreted in human milk, caution should be exercised when this medicine is used by a nursing woman. Avoid applying to the breast area to prevent infant exposure.

💊 Overdose Management

Overdose with this topical medicine is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of systemic corticosteroid overdose may include nausea, vomiting, and electrolyte imbalance. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

For external use only. Apply a thin layer to the affected area and rub in gently. Wash your hands before and after application unless your hands are the treated area. Avoid contact with eyes, mouth, and other mucous membranes. Do not cover the treated area with tight bandages or dressings unless instructed by your doctor. Do not use this medicine for more than 2 weeks without medical advice. If your condition worsens or does not improve after 7 days, consult your doctor. Do not use this medicine on children under 2 years of age unless prescribed by a pediatrician. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep this medicine out of reach of children. Do not use this medicine after the expiry date.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to the effects of corticosteroids, including skin thinning and systemic absorption. Use the lowest effective dose for the shortest duration. Monitor for signs of skin atrophy and systemic effects.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. It should be used during pregnancy only if clearly needed. Avoid using it on large areas or for prolonged periods.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine on surgical wounds. It should not be applied to open wounds or areas of infection unless specifically directed. Corticosteroids can delay wound healing.

🦷 Dental Procedures

No specific considerations for dental procedures. However, inform your dentist if you are using this medicine, especially if you have a history of corticosteroid use.

💚 Lifestyle Tips for Better Results

🏃
Keep your skin well moisturized to prevent dryness and itching.
🥗
Avoid scratching the affected area to prevent skin damage and infection.
😴
Wear loose, cotton clothing to reduce irritation.
💧
Avoid known triggers such as harsh soaps, detergents, and allergens.
🧘
Maintain good hygiene and keep your nails trimmed to prevent scratching.
🌞
Manage stress as it can worsen skin conditions.

🏋️ Exercise Considerations

No specific exercise restrictions while using this medicine. However, if you have scabies, avoid close physical contact and sharing personal items until treatment is complete. If the treated area is on a joint or area prone to friction, take care to avoid excessive rubbing.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables to support skin health.
Include foods rich in omega-3 fatty acids, such as fish and flaxseeds, to reduce inflammation.
Stay well hydrated by drinking plenty of water.
Limit intake of processed foods and added sugars, which may worsen inflammation.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any dizziness or allergic reaction, avoid these activities until you feel better. For scabies, avoid close contact with colleagues until treatment is complete.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your condition worsens, if you experience severe side effects, or if there is no improvement after 7 days of use. Do not stop abruptly if you have been using it for a long time without consulting your doctor, as this may cause a flare-up.

📅 Long-Term Use Effects

Prolonged use of this medicine, especially over large areas or under occlusive dressings, can lead to skin thinning, stretch marks, and systemic absorption of hydrocortisone. Systemic effects may include adrenal suppression, Cushing's syndrome, and hyperglycemia. Regular monitoring by a doctor is recommended if long-term use is necessary. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Emollients and moisturizers

Can help soothe and protect the skin, reducing the need for topical corticosteroids.

Evidence: Well-established
Antihistamines

Oral antihistamines can help relieve itching, especially at night.

Evidence: Well-established
Phototherapy

For chronic skin conditions, phototherapy may be considered under medical supervision.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction between this topical medicine and vaccines. However, if you are using this medicine over a large area or for a prolonged period, inform your doctor before receiving any live vaccines, as corticosteroids can suppress the immune system.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep the tube tightly closed

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially when traveling internationally. Store at room temperature and protect from extreme heat or cold. Keep it in your carry-on luggage if flying. No time zone adjustments are needed for topical application. Declare it to customs if required.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with eczema on her hands
She was prescribed this medicine to apply twice daily. After 3 days, her itching reduced significantly, and after a week, the redness and scaling improved. She was advised to use a moisturizer along with the cream and to avoid harsh soaps.
💡 Lesson: Consistent application and avoiding irritants help achieve better results with this medicine.
👤 A 28-year-old man with scabies
He was instructed to apply this medicine from the neck down, leave it on for 24 hours, and then wash it off. He repeated the application after 24 hours. His itching subsided within a few days, and the rash cleared within two weeks. He also treated his family members to prevent reinfestation.
💡 Lesson: Proper application technique and treating close contacts are essential for scabies treatment success.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Relief from itching may begin within a few hours to days. Anti-inflammatory effects typically become noticeable within 1 to 3 days of regular use.

Q: Can I use this medicine on my face?

A: No, unless specifically directed by your doctor. It should not be used on the face, groin, or underarms because these areas are more sensitive to corticosteroids.

Q: Is this medicine safe for children?

A: This medicine is not recommended for children under 2 years of age. For older children, consult a pediatrician for appropriate dosing.

Q: Can I use this medicine during pregnancy?

A: Consult your doctor before use. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Q: What should I do if I miss a dose?

A: Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long can I use this medicine?
  • Is this medicine safe for children?
  • Can I use this medicine during pregnancy?
  • What if I miss a dose?
  • Can I use this medicine with other skin products?
  • Does this medicine cure scabies?
  • What are the signs of an allergic reaction?

🔄 Substitutes for crotol hc cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used on any skin rash.
    Fact: This medicine is only for specific conditions like eczema, dermatitis, insect bites, and scabies. It should not be used on bacterial or fungal infections.
  • Myth: More cream means faster relief.
    Fact: Applying more than a thin layer does not speed up healing and may increase side effects.
  • Myth: This medicine is safe for long-term use.
    Fact: Prolonged use can cause skin thinning and systemic effects. Use only as directed for the prescribed duration.

🔄 Alternative Options

Generic Alternatives

  • Hydrocortisone 0.25% + Crotamiton 10% cream (generic)

Brand Alternatives

  • Crotorax HC Cream

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Hydrocortisone 0.25% + Crotamiton 10%","uses":"Itching, inflammation, scabies","route":"Topical"},{"medicine":"Hydrocortisone cream","composition":"Hydrocortisone 1%","uses":"Inflammation, itching","route":"Topical"},{"medicine":"Crotamiton cream","composition":"Crotamiton 10%","uses":"Scabies, itching","route":"Topical"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory