Jamopenz-H Suppository: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction with swelling of face, lips, or throat, or difficulty breathing.
- Heavy rectal bleeding or blood in stool.
- Severe pain in the rectal area that does not improve.
- Signs of infection such as fever, chills, or increased redness and discharge.
- Symptoms of high blood sugar such as increased thirst, frequent urination, or confusion.
- Signs of fluid retention such as swelling of ankles or sudden weight gain.
- Visual disturbances or severe headache.
If experiencing severe symptoms, call emergency services immediately.
What is pileum suppository used for?
This medicine is a rectal suppository containing hydrocortisone and zinc oxide. It is used to relieve inflammation, itching, and discomfort associated with hemorrhoids and other anal conditions. It works by reducing inflammation and protecting the irritated area.
- Generic Name: Hydrocortisone (0.25% w/w) + Zinc Oxide (5% w/w)
- Manufacturer: MMC Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 pileum suppository के बारे में (Hindi Summary)
उपयोग: यह दवा मलाशय में डालने वाली सपोजिटरी है जिसमें हाइड्रोकोर्टिसोन और जिंक ऑक्साइड होते हैं। यह बवासीर, गुदा में खुजली, जलन और सूजन को कम करने के लिए इस्तेमाल की जाती है। हाइड्रोकोर्टिसोन सूजन और खुजली को कम करता है, जबकि जिंक ऑक्साइड प्रभावित हिस्से को सुरक्षा देता है और आराम पहुंचाता है। इस दवा का उपयोग डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में डालने की जगह पर हल्की जलन, खुजली या असुविधा शामिल हो सकती है। कभी-कभी एलर्जी के कारण लालिमा या दाने भी हो सकते हैं। लंबे समय तक इस्तेमाल करने से त्वचा पतली हो सकती है और संक्रमण का खतरा बढ़ सकता है। गंभीर एलर्जी प्रतिक्रिया में चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई हो सकती है। ऐसा होने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा का इस्तेमाल डॉक्टर के बताए अनुसार ही करें। उपयोग से पहले और बाद में हाथ धोएं। सपोजिटरी को मलाशय में धीरे से डालें। अगर सपोजिटरी नरम हो जाए तो उसे फ्रिज में कुछ मिनट रखकर ठंडा करें। इस दवा को 7 दिन से ज्यादा इस्तेमाल न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 pileum suppository Uses & Benefits
[{"condition":"Hemorrhoids","description":"This medicine helps reduce inflammation, itching, and pain associated with internal and external hemorrhoids.","evidence":"Well-established for short-term symptomatic relief"},{"condition":"Anal itching (pruritus ani)","description":"The combination of hydrocortisone and zinc oxide soothes irritation and protects the anal area from further irritation.","evidence":"Commonly used, supported by clinical experience"},{"condition":"Anal fissures","description":"This medicine may help reduce inflammation and pain associated with small tears in the anal lining, though it does not heal the fissure itself.","evidence":"Limited evidence, often used as adjunct"},{"condition":"Post-operative rectal discomfort","description":"After certain rectal procedures, this medicine may be used to reduce local inflammation and provide comfort.","evidence":"Clinical experience"}]
Off-label uses: [{"condition":"Diaper rash with secondary inflammation","description":"Sometimes recommended by clinicians for short-term use in adults or older children with severe diaper rash, but not a standard use for a rectal suppository.","evidence":"Limited"},{"condition":"Localized inflammatory skin conditions near the anal area","description":"May be used off-label for other inflammatory conditions of the perianal skin, but only under medical supervision.","evidence":"Limited"}]
Primary treatment for: Hemorrhoids
Also treats: Anal itching, Anal fissures, Post-operative rectal discomfort
📋 Drug Information
| Generic Name(s) | Hydrocortisone (0.25% w/w) + Zinc Oxide (5% w/w) |
| Brand Name | pileum suppository |
| Manufacturer | MMC Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | |
| Route of Administration | Rectal |
| Storage | Store below 25°C in a cool, dry place. Do not freeze. Keep the suppositories in their original packaging to protect from light and moisture. If the suppository becomes soft, place it in the refrigerator for a few minutes to firm up before use. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Hydrocortisone is a corticosteroid that binds to glucocorticoid receptors inside cells, leading to reduced production of inflammatory mediators such as prostaglandins and leukotrienes. This decreases redness, swelling, itching, and pain in the rectal area. Zinc oxide acts as a physical barrier and a mild astringent. It forms a protective layer over the irritated mucosa, reducing exposure to moisture, stool, and other irritants, and it also has mild antiseptic and soothing properties. Together, these actions provide symptomatic relief from local inflammation and irritation.
Mechanism Steps
💡 How to Take pileum suppository
Strength: Rectal suppository containing hydrocortisone 0.25% w/w and zinc oxide 5% w/w.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one suppository inserted into the rectum once or twice daily, or as directed by your doctor. The frequency and duration of use depend on the condition being treated and your response to therapy. Do not use for more than 7 days without consulting a doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more susceptible to the systemic effects of corticosteroids. Use the lowest effective dose for the shortest possible duration. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Renal Impairment | No specific dose adjustment is established for patients with renal impairment. However, use with caution and consult your doctor, as systemic absorption of hydrocortisone may occur. |
| Hepatic Impairment | No specific dose adjustment is established for patients with hepatic impairment. Use with caution and consult your doctor, as hydrocortisone is metabolized in the liver. |
| Maximum Daily Dose | The maximum recommended daily dose is generally two suppositories per day, but this may vary based on medical advice. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of pileum suppository
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Oral corticosteroids | Major | |
| Antidiabetic drugs | Moderate | |
| Diuretics | Moderate | |
| NSAIDs | Moderate | |
| Antacids | Minor | |
| Topical zinc products | Minor |
🚨 Major Interactions
- Corticosteroids (oral or injectable)
- Anticoagulants (e.g., warfarin)
⚡ Moderate Interactions
- Antidiabetic drugs
- Diuretics
- NSAIDs
🍷 Alcohol Interaction
Alcohol does not directly interact with this medicine when used rectally. However, alcohol can worsen inflammation and irritate the digestive tract, which may counteract the benefits of this medicine. It is advisable to limit alcohol consumption while treating hemorrhoids or anal irritation.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to hydrocortisone, zinc oxide, or any other ingredient in the suppository.","Untreated bacterial, fungal, or viral infections of the rectal area.","Tuberculosis of the rectum or other local infections.","Recent rectal surgery or trauma, unless specifically directed by a doctor.","Children under 12 years of age, unless prescribed by a doctor."]
⚠️ Warnings & Precautions
["For rectal use only. Do not take by mouth.","Do not use for longer than the recommended duration without medical advice.","If symptoms persist or worsen after a few days, stop use and consult a doctor.","Avoid contact with eyes. If accidental contact occurs, rinse thoroughly with water.","Keep out of reach of children.","Do not use if the suppository is damaged or discolored.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Inform your doctor about all other medicines you are taking, especially oral corticosteroids, anticoagulants, and antidiabetic drugs.","Patients with diabetes, glaucoma, or a history of immune suppression should use this medicine only under medical supervision.","Prolonged use may increase the risk of local infection and skin thinning."]
🤱 Lactation Safety
It is not known whether hydrocortisone from this rectal suppository passes into breast milk in significant amounts. Zinc oxide is not absorbed systemically. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose with this medicine is unlikely due to its rectal route and low systemic absorption. If someone accidentally ingests the suppository, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, and signs of systemic corticosteroid excess. Treatment is supportive and symptomatic. Contact a poison control center or emergency department for advice.
⏰ Missed Dose
If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not use a double dose to make up for a missed one.
Additional Safety Advice
Use this medicine exactly as directed by your doctor. Wash your hands thoroughly before and after inserting the suppository. If the suppository is soft, you may place it in the refrigerator for a few minutes to firm it up before use. Do not use this medicine if the suppository is damaged or discolored. Avoid using this product for more than the recommended duration without consulting your doctor. Do not use this medicine on broken skin or in the presence of an untreated infection. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine. Keep this medicine out of the reach of children. Do not share this medicine with anyone else, even if they have similar symptoms. If your symptoms do not improve within a few days or if they get worse, stop using the medicine and seek medical advice. Inform your doctor about all other medicines you are taking, including prescription and over-the-counter products, before starting this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the systemic effects of corticosteroids. Use the lowest effective dose for the shortest duration. Monitor for signs of fluid retention, high blood sugar, and high blood pressure.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Hydrocortisone is generally considered low risk when used topically in small amounts, but medical advice is recommended.
🏥 Post-Surgery Considerations
After rectal surgery, use this medicine only if prescribed by your surgeon. It may help reduce inflammation and discomfort, but it should not be used on infected or healing wounds without medical supervision.
🦷 Dental Procedures
This medicine is not expected to interfere with dental procedures. However, inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid heavy lifting or strenuous exercise that increases pressure on the rectal area. Gentle walking and light activities are usually fine. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to work or drive. However, if you experience any discomfort or dizziness, avoid driving or operating heavy machinery until you feel better.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any severe side effects such as allergic reactions or signs of infection.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to thinning of the skin or mucosal tissue, increased risk of local infections, and systemic corticosteroid effects such as increased blood sugar, fluid retention, and high blood pressure. It is recommended to use this medicine for the shortest duration necessary and under medical supervision. Regular follow-up with your doctor is advised if prolonged use is required.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Soaking in warm water for 15 minutes several times a day can help relieve hemorrhoid symptoms.
Evidence: Well-establishedIncreasing fiber intake can soften stool and reduce straining.
Evidence: Well-establishedProducts containing lidocaine or other numbing agents can provide temporary relief.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccination considerations are associated with this medicine. However, if you are due for any vaccines, inform your doctor about your medication.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not freeze unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry your suppositories in their original packaging along with a copy of your prescription. Store them in a cool, dry place, away from direct sunlight. If you are traveling to a different time zone, continue with your regular dosing schedule as prescribed. Check customs regulations for carrying prescription medicines to your destination. If the suppositories become soft, place them in a refrigerator or a cool bag to firm up before use.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts providing relief from itching and discomfort within 15 to 30 minutes after insertion.
A: Wash your hands, lie on your side, and gently insert the suppository into the rectum, pointed end first. Stay lying down for a few minutes.
A: No, you should not use this medicine for more than 7 days without consulting your doctor, as prolonged use can increase the risk of side effects.
A: Consult your doctor before using this medicine during pregnancy. Hydrocortisone is generally considered low risk when used topically in small amounts, but medical advice is necessary.
A: If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for pileum suppository
View AllAlternative brands with exact same active ingredient:
-
anomex suppositoryBliss Gvs Pharma Limited ₹50.63 43.2% CHEAPER
-
corect suppositoryMeridian Enterprises Pvt Ltd ₹93.75 5.3% COSTLIER
-
anaproct ointmentInd Swift Laboratories Ltd ₹116.02 30.3% COSTLIER
-
jamopenz-h suppositoryArk Life Sciences Pvt Ltd ₹328.13 268.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure hemorrhoids permanently.
Fact: This medicine provides symptomatic relief but does not cure the underlying condition. Lifestyle changes and medical treatment may be needed. - Myth: More frequent use will make it work faster.
Fact: Using more than prescribed can increase the risk of side effects and does not improve results. Follow your doctor's instructions. - Myth: It is safe to use for months without consulting a doctor.
Fact: Prolonged use can lead to skin thinning, increased risk of infection, and systemic corticosteroid effects. Use only as directed.
🔄 Alternative Options
Generic Alternatives
- Hydrocortisone and zinc oxide rectal suppositories from other manufacturers.
Brand Alternatives
- Jamopenz-H Suppository