Acsolve C Gel: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe or bloody diarrhea
- Severe abdominal pain or cramps
- Fever with diarrhea
- Swelling of the face, lips, or throat
- Difficulty breathing
- Severe skin blistering or peeling
- Yellowing of the skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is atoin c gel used for?
This medicine is a topical gel containing clindamycin 1% and tretinoin 0.025%, used to treat moderate to severe acne by reducing bacteria and unclogging pores. Apply a thin layer once daily at bedtime.
- Generic Name: Clindamycin + Tretinoin
- Manufacturer: Canbro Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 atoin c gel के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल जेल है जिसमें क्लिंडामाइसिन 1% और ट्रेटिनोइन 0.025% होते हैं। यह मुँहासे (एक्ने) के इलाज के लिए इस्तेमाल की जाती है। यह त्वचा पर मुँहासे पैदा करने वाले बैक्टीरिया को मारती है और बंद रोमछिद्रों को खोलती है। यह दवा मध्यम से गंभीर मुँहासे के लिए प्रभावी है। इसे रात में सोने से पहले पतली परत में लगाएँ। इसका इस्तेमाल डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में त्वचा का सूखना, पपड़ी बनना, लालिमा, जलन, खुजली और धूप के प्रति संवेदनशीलता शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में कम हो जाते हैं। कभी-कभी शुरुआत में मुँहासे बढ़ते हुए लग सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको गंभीर दस्त, पेट दर्द, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का इस्तेमाल करने से पहले अपने डॉक्टर को अपनी एलर्जी और चिकित्सीय स्थिति के बारे में बताएं। इसे आँखों, होंठों और श्लेष्मा झिल्ली से दूर रखें। धूप में बाहर निकलने से बचें और सनस्क्रीन का इस्तेमाल करें। गर्भवती या स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के इसका इस्तेमाल न करें। इसे बच्चों की पहुंच से दूर रखें। दूसरों के साथ साझा न करें।
💊 atoin c gel Uses & Benefits
[{"condition":"Acne vulgaris","description":"This medicine is used for the topical treatment of moderate to severe acne vulgaris, reducing both inflammatory and non-inflammatory lesions.","evidence":"Well-established"},{"condition":"Comedonal acne","description":"The tretinoin component helps to unclog pores and reduce blackheads and whiteheads.","evidence":"Well-established"},{"condition":"Inflammatory acne","description":"The clindamycin component targets Cutibacterium acnes and reduces inflammation.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Rosacea","description":"Sometimes prescribed off-label for rosacea with inflammatory papules, but evidence is limited.","evidence":"Limited"},{"condition":"Keratosis pilaris","description":"Tretinoin may help with keratin plugs, but combination with clindamycin is not standard.","evidence":"Limited"}]
Primary treatment for: Acne vulgaris
Also treats: Comedonal acne, Inflammatory acne
📋 Drug Information
| Generic Name(s) | Clindamycin + Tretinoin |
| Brand Name | Acsolve C Gel |
| Manufacturer | Canbro Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Antibiotic + Retinoid |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Keep the tube tightly closed when not in use. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Clindamycin is a lincosamide antibiotic that binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby stopping the growth of Cutibacterium acnes. Tretinoin is a retinoid that binds to retinoic acid receptors in the skin, modulating gene expression to promote keratinocyte turnover, reduce comedone formation, and decrease inflammation. Together, they reduce bacterial load and prevent new acne lesions.
Mechanism Steps
💡 How to Take atoin c gel
Strength: Gel containing clindamycin 1% w/w and tretinoin 0.025% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected areas of the skin once daily, usually at bedtime, or as directed by your doctor. Wash and dry the skin gently before application. Avoid applying to unaffected areas. The dose and frequency may be adjusted by your doctor based on your response and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dosage adjustments are established for elderly patients. Use with caution and under medical supervision. |
| Renal Impairment | No specific dosage adjustments are established for renal impairment. Use with caution in severe renal impairment. |
| Hepatic Impairment | No specific dosage adjustments are established for hepatic impairment. Use with caution in severe hepatic impairment. |
| Maximum Daily Dose | Not established from the available information. Use only as prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of atoin c gel
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other topical retinoids | Major | |
| Erythromycin | Moderate | |
| Neuromuscular blockers | Major | |
| Oral isotretinoin | Moderate | |
| Abrasive cleansers | Minor |
🚨 Major Interactions
- Other topical retinoids or keratolytics
- Neuromuscular blocking agents
⚡ Moderate Interactions
- Erythromycin
- Oral isotretinoin
🍷 Alcohol Interaction
No significant interaction is expected with alcohol when this medicine is used topically. However, alcohol consumption may worsen skin conditions and should be limited.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to clindamycin, tretinoin, or any component of the gel","History of inflammatory bowel disease or ulcerative colitis","Severe eczema or other chronic skin conditions","Pregnancy or planning pregnancy","Breastfeeding without medical advice"]
⚠️ Warnings & Precautions
["For external use only. Avoid contact with eyes, lips, and mucous membranes.","May cause skin irritation. Discontinue if severe irritation occurs.","May increase sensitivity to sunlight. Use sunscreen and protective clothing.","Do not use on broken or irritated skin.","Clindamycin can cause severe colitis. Stop use and consult doctor if diarrhea develops.","Avoid concurrent use with other topical acne products unless advised.","Keep out of reach of children.","Do not use for prolonged periods without medical supervision."]
🤱 Lactation Safety
It is not known whether clindamycin and tretinoin are excreted in human milk after topical application. Because many drugs are excreted in human milk, caution should be exercised when this medicine is used by a nursing woman. Consult your doctor.
💊 Overdose Management
Overdose with topical application is unlikely. If excessive application occurs, wash the area with water and discontinue use. If ingested, seek medical attention immediately. Treatment is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Before using this medicine, inform your doctor if you are allergic to clindamycin, tretinoin, or any other medications. Do not use this medicine if you have a history of inflammatory bowel disease, ulcerative colitis, or severe eczema. Avoid contact with the eyes, lips, and mucous membranes. If accidental contact occurs, rinse thoroughly with water. This medicine may make your skin more sensitive to sunlight, so use sunscreen daily and avoid prolonged sun exposure. Do not use other topical acne products unless advised by your doctor, as they may increase irritation. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not apply this medicine to cuts, scrapes, or irritated skin. Wash your hands before and after applying the gel. Use a gentle, non-comedogenic moisturizer if dryness occurs. Do not cover the treated area with tight bandages or dressings unless instructed. Keep this medicine out of reach of children. Do not share this medicine with others, even if they have similar symptoms. If you develop severe diarrhea, abdominal cramps, or bloody stools, stop using this medicine and contact your doctor immediately. Regular follow-up with your dermatologist is recommended to monitor progress and adjust treatment as needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Acne is less common in the elderly, but if prescribed, use with caution due to potentially more sensitive skin. Monitor for excessive irritation.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Topical tretinoin is not recommended during pregnancy due to potential risk of birth defects. Your doctor may recommend alternative acne treatments.
🏥 Post-Surgery Considerations
If you have recently had surgery, consult your doctor before using this medicine on the surgical area. Avoid applying to healing wounds.
🦷 Dental Procedures
No specific considerations for dental procedures. Continue using this medicine as prescribed unless your doctor advises otherwise.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while using this medicine. However, sweat may irritate the skin, so wash your face gently after exercising. Avoid touching your face with dirty hands or equipment.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to work or drive. However, if you experience significant skin irritation or sensitivity, you may want to avoid prolonged sun exposure during work hours. It is generally safe to continue your daily activities.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if you develop severe skin irritation, allergic reactions, or severe diarrhea. Do not stop abruptly without consulting your doctor, as acne may recur. Your doctor will advise you on the appropriate duration of treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to bacterial resistance to clindamycin. It is generally recommended to use it for a limited duration, usually 12 weeks, unless otherwise directed by your doctor. Regular follow-up is important to monitor for side effects and effectiveness. Prolonged use may also increase the risk of skin irritation and sensitivity.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An alternative topical treatment for mild to moderate acne.
Evidence: Well-establishedHelps unclog pores and exfoliate the skin.
Evidence: Well-establishedFor severe acne, oral antibiotics like doxycycline may be prescribed.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccination considerations are associated with this medicine. Continue with your regular vaccination schedule.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, keep it in its original packaging and carry a copy of your prescription. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, continue applying it once daily at your usual bedtime routine. Customs may require documentation for prescription medications, so keep your prescription handy. Do not leave it in a hot car or in direct sunlight.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start seeing improvement in 2 to 4 weeks, but full effects may take 8 to 12 weeks of consistent use.
A: Consult your doctor before combining with other acne treatments, as it may increase irritation.
A: Avoid sun exposure, abrasive cleansers, and other topical irritants. Do not use on broken skin.
A: Topical tretinoin is not recommended during pregnancy. Consult your doctor for alternative treatments.
A: Yes, peeling is a common side effect, especially in the first few weeks. It usually subsides with continued use.
🤔 Common Patient Concerns
🔄 Substitutes for atoin c gel
View AllAlternative brands with exact same active ingredient:
-
acsolve c gelInd Swift Laboratories Ltd ₹45.84 55.6% CHEAPER
-
acsolve c creamInd Swift Laboratories Ltd ₹46.70 54.7% CHEAPER
-
treclin gelElder Pharmaceuticals Ltd ₹60.00 41.8% CHEAPER
-
Acnegel T GelWest-Coast Pharmaceutical Works Ltd ₹60.80 41% CHEAPER
-
tretin c gelPsycormedies ₹72.19 30% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine works overnight.
Fact: It may take several weeks to see improvement. - Myth: More application means faster results.
Fact: Applying more than prescribed can increase irritation without speeding results. - Myth: You can stop using it once acne clears.
Fact: Stopping too soon may lead to recurrence. Follow your doctor's advice.
🔄 Alternative Options
Generic Alternatives
- Clindamycin 1% and tretinoin 0.025% gel (generic)