creval 10mg tablet - Uses, Price, Side Effects & Substitutes
What is creval 10mg tablet used for?
Artival (Valdecoxib) is used to treat PAIN ANALGESICS. It contains Valdecoxib (10mg), which Selective inhibition of cyclooxygenase-2 (COX-2), reducing prostaglandin synthes. Always consult your doctor before use. Take as prescribed.
- Generic Name: Valdecoxib
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ creval 10mg tablet Uses & Benefits
Management of osteoarthritis, rheumatoid arthritis, dysmenorrhea, acute pain.
Off-label uses: Ankylosing spondylitis, acute gouty arthritis.
๐ Drug Information
| Generic Name(s) | Valdecoxib |
| Brand Name | Artival |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's -Selective COX-2 Inhibitors |
| Route of Administration | Oral. |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Selective inhibition of cyclooxygenase-2 (COX-2), reducing prostaglandin synthesis.
Mechanism Steps
๐ก How to Take creval 10mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of creval 10mg tablet
โ Common Side Effects
- Headache
- Dyspepsia
- Diarrhea
- Upper respiratory tract infection
- Sinusitis
๐จ Serious Side Effects
- Gastrointestinal bleeding
- Cardiovascular thrombotic events
- Renal failure
- Anaphylaxis
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Hepatitis
- Pancreatitis
- Aseptic meningitis
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Major | Increased risk of GI ulceration and bleeding |
| Lithium | Major | Increased lithium levels and toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| ACE inhibitors | Major | Reduced antihypertensive effect |
| Diuretics | Major | Reduced diuretic effect, increased risk of renal impairment |
| Fluconazole | Moderate | Increased valdecoxib levels |
| Ketoconazole | Moderate | Increased valdecoxib levels |
| CYP2C9 inhibitors | Moderate | Increased valdecoxib levels |
| CYP3A4 inhibitors | Moderate | Increased valdecoxib levels |
| Antacids | Minor | Slight decrease in absorption |
| Corticosteroids | Minor | Increased risk of GI ulceration |
๐จ Major Interactions
- Warfarin
- Aspirin
- Lithium
- Methotrexate
- ACE inhibitors
- Diuretics
โก Moderate Interactions
- Fluconazole
- Ketoconazole
- CYP2C9 inhibitors
- CYP3A4 inhibitors
โน๏ธ Minor Interactions
- Antacids
- Corticosteroids
๐ฝ๏ธ Food Interactions
May be taken with or without food; food may delay absorption.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to valdecoxib or sulfonamides; history of asthma, urticaria, or allergic reactions to NSAIDs; severe hepatic impairment; active peptic ulcer; coronary artery bypass graft surgery; third trimester of pregnancy.
๐ Monitoring Parameters
Renal function, liver function, blood pressure, signs of GI bleeding, cardiovascular status.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk.
๐ Overdose Management
Symptomatic and supportive care; no specific antidote; consider activated charcoal if recent ingestion.
โฐ Missed Dose
Take as soon as remembered unless almost time for next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for creval 10mg tablet
View AllAlternative brands with exact same active ingredient (Valdecoxib (10mg)):
-
marvel 10mg tabletGlenmark Pharmaceuticals Ltd โน9.30 52.8% CHEAPER
-
valtic 10mg tabletWisdom Pharma Pvt. Ltd โน14.06 28.7% CHEAPER
-
voxx 10mg tabletBombay Tablet Mfg Co Pvt Ltd โน16.41 16.7% CHEAPER
-
velsaid 10mg tabletMacleods Pharmaceuticals Pvt Ltd โน17.53 11.1% CHEAPER
-
eldorin 10mg tabletKentreck Laboratories Pvt Ltd โน17.81 9.6% CHEAPER
-
artival 10mg tabletGeno Pharmaceuticals Ltd โน18.28 7.3% CHEAPER
-
vorth 10mg tabletGlenmark Pharmaceuticals Ltd โน18.28 7.3% CHEAPER
-
vah 10mg tabletAbbott โน18.45 6.4% CHEAPER
-
valed 10mg tabletAlkem Laboratories Ltd โน18.68 5.2% CHEAPER
-
valdixx 10mg tablet mdCipla Ltd โน18.73 5% CHEAPER
Medical Note: Always consult your doctor before switching medications.