creart 0.25mg injection - Cetrorelix (0.25mg) medicine

creart 0.25mg injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Xyata Life Sciences Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is creart 0.25mg injection used for?

Asporelix (Cetrorelix) is used to treat HORMONES. It contains Cetrorelix (0.25mg), which Cetrorelix is a synthetic decapeptide that acts as a competitive antagonist of g. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cetrorelix
  • Manufacturer: Xyata Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š creart 0.25mg injection Uses & Benefits

Prevention of premature luteinizing hormone surge in women undergoing controlled ovarian stimulation for assisted reproductive technology (ART).

Off-label uses: Treatment of hormone-sensitive cancers (e.g., prostate cancer), endometriosis, uterine fibroids (limited evidence).

๐Ÿ“‹ Drug Information

Generic Name(s)Cetrorelix
Brand NameAsporelix
ManufacturerXyata Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassHORMONES
Action ClassGNRH antagonists
Route of AdministrationSubcutaneous injection.
StorageStore at 2-8ยฐC (refrigerate); protect from light; do not freeze.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after subcutaneous injection; peak plasma concentration reached within 1-2 hours.
DistributionVolume of distribution approximately 1.1 L/kg; binds to plasma proteins.
Protein Binding86% bound to plasma proteins.
MetabolismMetabolized by peptidases; no significant CYP450 involvement.
Half-LifeApproximately 36 hours after subcutaneous administration.
ExcretionPrimarily excreted in feces (about 70%) and urine (about 30%) as unchanged drug and metabolites.
BioavailabilityApproximately 85% after subcutaneous injection.
Onset of ActionRapid suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) within 1-2 hour
Peak Plasma Time1-2 hours post-injection.
Duration of ActionSuppression of gonadotropins persists for at least 24 hours; single dose effective for up to 7 days.

How It Works

Cetrorelix is a synthetic decapeptide that acts as a competitive antagonist of gonadotropin-releasing hormone (GnRH) at the pituitary GnRH receptors. It inhibits the release of LH and FSH, thereby suppressing ovarian steroidogenesis and preventing premature ovulation.

Mechanism Steps

1Cetrorelix binds competitively to GnRH receptors on pituitary gonadotropes.
2Blocks endogenous GnRH from binding, preventing receptor activation.
3Inhibits the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

๐Ÿ’ก How to Take creart 0.25mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of creart 0.25mg injection

โœ… Common Side Effects

  • Injection site reactions (pain, redness, swelling)
  • Nausea
  • Headache
  • Mild abdominal pain

๐Ÿšจ Serious Side Effects

  • Ovarian hyperstimulation syndrome (OHSS)
  • Allergic reactions (urticaria, angioedema)
  • Severe injection site reactions

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Thromboembolism
  • Ovarian torsion

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Gonadotropins Major Altered response to ovarian stimulation; dose adjustment may be needed.
Oral contraceptives Major Reduced contraceptive efficacy; alternative contraception recommended.
Corticosteroids Moderate Possible increased risk of ovarian hyperstimulation syndrome.
Antidiabetic agents Moderate May affect blood glucose levels; monitor glucose.
Anticoagulants Moderate Potential increased bleeding risk at injection site.

๐Ÿšจ Major Interactions

  • Gonadotropins
  • Oral contraceptives
  • Hormonal therapies

โšก Moderate Interactions

  • Corticosteroids
  • Antidiabetic agents
  • Anticoagulants

โ„น๏ธ Minor Interactions

  • None known

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to cetrorelix or any component; pregnancy; lactation; severe hepatic or renal impairment.

๐Ÿ“Š Monitoring Parameters

Serum estradiol levels, LH levels, follicular development via ultrasound, ovarian response.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk in animal studies; discontinue nursing or drug.

๐Ÿ’Š Overdose Management

No specific antidote; symptomatic and supportive care; monitor hormone levels.

โฐ Missed Dose

Administer as soon as remembered; if close to next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for creart 0.25mg injection

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Alternative brands with exact same active ingredient (Cetrorelix (0.25mg)):

Medical Note: Always consult your doctor before switching medications.

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