cetrolix 0.25 mg prefilled syringe

4.7 (15 reviews)

Cetrorelix (0.25mg)

🏭 Intas Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is cetrolix 0.25 mg prefilled syringe used for?

Asporelix (Cetrorelix) is used to treat HORMONES. It contains Cetrorelix (0.25mg), which Cetrorelix is a synthetic decapeptide that acts as a competitive antagonist of g. Always consult your doctor before use. Take as prescribed.

Generic Name: Cetrorelix
Manufacturer: Intas Pharmaceuticals Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 cetrolix 0.25 mg prefilled syringe Uses & Benefits

Prevention of premature luteinizing hormone surge in women undergoing controlled ovarian stimulation for assisted reproductive technology (ART).

Off-label uses: Treatment of hormone-sensitive cancers (e.g., prostate cancer), endometriosis, uterine fibroids (limited evidence).

📋 Drug Information

Generic Name(s)	Cetrorelix
Brand Name	Asporelix
Manufacturer	Intas Pharmaceuticals Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	HORMONES
Action Class	GNRH antagonists
Route of Administration	Subcutaneous injection.
Storage	Store at 2-8°C (refrigerate); protect from light; do not freeze.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after subcutaneous injection; peak plasma concentration reached within 1-2 hours.

DistributionVolume of distribution approximately 1.1 L/kg; binds to plasma proteins.

Protein Binding86% bound to plasma proteins.

MetabolismMetabolized by peptidases; no significant CYP450 involvement.

Half-LifeApproximately 36 hours after subcutaneous administration.

ExcretionPrimarily excreted in feces (about 70%) and urine (about 30%) as unchanged drug and metabolites.

BioavailabilityApproximately 85% after subcutaneous injection.

Onset of ActionRapid suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) within 1-2 hour

Peak Plasma Time1-2 hours post-injection.

Duration of ActionSuppression of gonadotropins persists for at least 24 hours; single dose effective for up to 7 days.

How It Works

Cetrorelix is a synthetic decapeptide that acts as a competitive antagonist of gonadotropin-releasing hormone (GnRH) at the pituitary GnRH receptors. It inhibits the release of LH and FSH, thereby suppressing ovarian steroidogenesis and preventing premature ovulation.

Mechanism Steps

1Cetrorelix binds competitively to GnRH receptors on pituitary gonadotropes.

2Blocks endogenous GnRH from binding, preventing receptor activation.

3Inhibits the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

💡 How to Take cetrolix 0.25 mg prefilled syringe

Follow your doctor's prescription exactly.

⚠️ Side Effects of cetrolix 0.25 mg prefilled syringe

✅ Common Side Effects

Injection site reactions (pain, redness, swelling)
Nausea
Headache
Mild abdominal pain

🚨 Serious Side Effects

Ovarian hyperstimulation syndrome (OHSS)
Allergic reactions (urticaria, angioedema)
Severe injection site reactions

⚠️ Rare Side Effects

Anaphylaxis
Thromboembolism
Ovarian torsion

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Gonadotropins	Major	Altered response to ovarian stimulation; dose adjustment may be needed.
Oral contraceptives	Major	Reduced contraceptive efficacy; alternative contraception recommended.
Corticosteroids	Moderate	Possible increased risk of ovarian hyperstimulation syndrome.
Antidiabetic agents	Moderate	May affect blood glucose levels; monitor glucose.
Anticoagulants	Moderate	Potential increased bleeding risk at injection site.

🚨 Major Interactions

Gonadotropins
Oral contraceptives
Hormonal therapies

⚡ Moderate Interactions

Corticosteroids
Antidiabetic agents
Anticoagulants

ℹ️ Minor Interactions

None known

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to cetrorelix or any component; pregnancy; lactation; severe hepatic or renal impairment.

📊 Monitoring Parameters

Serum estradiol levels, LH levels, follicular development via ultrasound, ovarian response.

🤱 Lactation Safety

Not recommended; excreted in breast milk in animal studies; discontinue nursing or drug.

💊 Overdose Management

No specific antidote; symptomatic and supportive care; monitor hormone levels.

⏰ Missed Dose

Administer as soon as remembered; if close to next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.