covishield vaccine - Uses, Price, Side Effects & Substitutes
What is covishield vaccine used for?
Covishield Vaccine (ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant)) is used to treat VACCINES. It contains ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant) (NA), which The vaccine uses a replication-deficient chimpanzee adenovirus vector to deliver. Always consult your doctor before use. Take as prescribed.
- Generic Name: ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant)
- Manufacturer: Serum Institute Of India Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ covishield vaccine Uses & Benefits
Active immunization against COVID-19 caused by SARS-CoV-2 virus.
Off-label uses: Booster doses in immunocompromised individuals, Use in children (if authorized)
๐ Drug Information
| Generic Name(s) | ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant) |
| Brand Name | Covishield Vaccine |
| Manufacturer | Serum Institute Of India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VACCINES |
| Action Class | Viral Vector Vaccine |
| Route of Administration | Intramuscular injection (deltoid muscle) |
| Storage | Store at 2ยฐC to 8ยฐC; do not freeze. Protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
The vaccine uses a replication-deficient chimpanzee adenovirus vector to deliver the SARS-CoV-2 spike protein gene, inducing both humoral and cellular immune responses.
Mechanism Steps
๐ก How to Take covishield vaccine
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of covishield vaccine
โ Common Side Effects
- Injection site pain
- Fatigue
- Headache
- Myalgia
- Fever
- Chills
- Nausea
๐จ Serious Side Effects
- Anaphylaxis
- Thrombosis with thrombocytopenia syndrome (TTS)
- Guillain-Barre syndrome
- Myocarditis
โ ๏ธ Rare Side Effects
- Capillary leak syndrome
- Transverse myelitis
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Immunosuppressants | Major | Reduced vaccine efficacy |
| Corticosteroids | Major | Reduced immune response |
| Methotrexate | Moderate | Possible reduced antibody response |
| NSAIDs | Minor | May reduce fever response; no significant interaction |
๐จ Major Interactions
- Immunosuppressants
- Corticosteroids
- Antimetabolites
- Alkylating agents
- TNF inhibitors
โก Moderate Interactions
- Methotrexate
- Azathioprine
- Cyclosporine
- Mycophenolate
- Rituximab
โน๏ธ Minor Interactions
- NSAIDs
- Antihistamines
- Paracetamol
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
History of severe allergic reaction to a previous dose or any component of the vaccine.
๐ Monitoring Parameters
Monitor for immediate allergic reactions (15-30 minutes post-vaccination); observe for adverse events.
๐คฑ Lactation Safety
Likely safe; vaccine components not excreted in milk in significant amounts.
๐ Overdose Management
No specific treatment; monitor for adverse reactions and provide supportive care.
โฐ Missed Dose
Administer as soon as possible; do not restart the series. Follow recommended interval for second dose.