Avaxim 80U Pediatric Vaccine: Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or wheezing after vaccination.
- Swelling of the face, lips, tongue, or throat.
- Rapid heartbeat, dizziness, or fainting.
- High fever (above 39°C) that does not respond to medication.
- Severe allergic reaction with hives or rash.
- Seizures or convulsions.
- Persistent crying or irritability for more than 48 hours.
If experiencing severe symptoms, call emergency services immediately.
What is avaxim 80u pediatric vaccine used for?
This medicine is a hepatitis A vaccine given by intramuscular injection to prevent hepatitis A infection. It contains a weakened form of the virus that stimulates immunity without causing disease. It is given as a single dose in children, with a booster after 6 to 12 months.
- Generic Name: Hepatitis A Vaccine (Inactivated)
- Manufacturer: Sanofi India Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 avaxim 80u pediatric vaccine के बारे में (Hindi Summary)
उपयोग: यह दवा हेपेटाइटिस ए (पीलिया) से बचाव के लिए दी जाने वाली वैक्सीन है। इसमें हेपेटाइटिस ए वायरस का कमजोर रूप होता है, जो शरीर में रोग नहीं फैलाता बल्कि प्रतिरक्षा प्रणाली को मजबूत करता है। यह इंजेक्शन के रूप में ऊपरी बांह की मांसपेशी में लगाई जाती है। यह मुख्य रूप से बच्चों और किशोरों के लिए है, लेकिन जोखिम वाले वयस्कों को भी दी जा सकती है। एक खुराक के बाद 6 से 12 महीने में बूस्टर डोज दी जाती है। यह वैक्सीन हेपेटाइटिस ए से बचाव करती है, लेकिन हेपेटाइटिस बी, सी या ई से नहीं बचाती।
साइड इफेक्ट्स: इस वैक्सीन के सामान्य दुष्प्रभाव हल्के और अस्थायी होते हैं। इंजेक्शन वाली जगह पर दर्द, लालिमा या सूजन हो सकती है, जो आमतौर पर 1-2 दिन में ठीक हो जाती है। कुछ बच्चों को हल्का बुखार, चिड़चिड़ापन या सिरदर्द हो सकता है। गंभीर दुष्प्रभाव बहुत दुर्लभ हैं। कभी-कभी एलर्जी की गंभीर प्रतिक्रिया हो सकती है, जिसमें सांस लेने में कठिनाई, चेहरे या गले में सूजन, तेज धड़कन और चक्कर आना शामिल है। ऐसा होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह वैक्सीन केवल योग्य स्वास्थ्यकर्मी द्वारा ही लगाई जानी चाहिए। टीकाकरण से पहले अपने डॉक्टर को किसी भी एलर्जी, विशेष रूप से नियोमाइसिन या अन्य एंटीबायोटिक्स से, के बारे में बताएं। यदि बच्चे को रक्तस्राव विकार है या वह रक्त पतला करने वाली दवा ले रहा है, तो डॉक्टर को सूचित करें। तेज बुखार के दौरान टीकाकरण टाल दें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें। टीकाकरण के बाद भी स्वच्छता का पालन करें। टीके का रिकॉर्ड रखें।
💊 avaxim 80u pediatric vaccine Uses & Benefits
- [{"condition":"Hepatitis A prevention","description":"This vaccine is used to prevent hepatitis A infection in children and adolescents.
- It stimulates active immunity against the hepatitis A virus.","evidence":"Well-established"},{"condition":"Pre-exposure prophylaxis for travellers","description":"Recommended for individuals travelling to regions where hepatitis A is endemic or where sanitation is poor.","evidence":"Well-established"},{"condition":"Chronic liver disease patients","description":"Vaccination is advised for people with chronic liver disease to prevent additional liver damage from hepatitis A.","evidence":"Well-established"},{"condition":"Occupational risk groups","description":"Healthcare workers, sewage workers, and laboratory personnel handling hepatitis A virus may be vaccinated.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Hepatitis A prevention
Also treats: Chronic liver disease, Travel to endemic areas, Occupational exposure
📋 Drug Information
| Generic Name(s) | Hepatitis A Vaccine (Inactivated) |
| Brand Name | Avaxim 80U Pediatric |
| Manufacturer | Sanofi India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VACCINES |
| Action Class | Killed vaccine |
| Route of Administration | Intramuscular injection, preferably into the deltoid muscle of the upper arm |
| Storage | Store in a refrigerator at 2°C to 8°C. Do not freeze. Keep away from direct sunlight. Do not use if the vaccine has been frozen. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. Consult local immunization guidelines. |
| ICMR Guideline | Not established from the available information. Consult local immunization guidelines. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine contains a live attenuated hepatitis A virus that has been weakened so it cannot cause disease in healthy individuals. After intramuscular injection, the virus replicates locally and in the liver, stimulating the immune system to produce specific antibodies (IgM and IgG) against hepatitis A. The immune response includes activation of helper T cells and cytotoxic T cells, which help clear the virus and create memory B cells. These memory cells provide long-term protection by rapidly producing antibodies if the person is later exposed to wild-type hepatitis A virus. The attenuated virus does not cause hepatitis but induces a robust and durable immune response similar to natural infection.
Mechanism Steps
💡 How to Take avaxim 80u pediatric vaccine
Strength: Freeze-dried live attenuated hepatitis A vaccine, 80 IU per dose, for intramuscular injection.
Dosage Information
| Adult Dosage | This vaccine is primarily indicated for children and adolescents. For adults, the dosage is typically a single 80 IU dose given intramuscularly, followed by a booster dose after 6 to 12 months. The exact dose and schedule must be individualized by a qualified clinician based on the patient's age, health status, and immunization history. |
| Pediatric Dosage | For children and adolescents, a single 80 IU dose is given intramuscularly. A booster dose is recommended 6 to 12 months later. The exact dose and timing should be determined by a pediatrician based on the child's age and local immunization guidelines. |
| Elderly Dosage | Not established from the available information. Consult a doctor for individualized recommendations. |
| Renal Impairment | Not established from the available information. No dose adjustment is typically required for renal impairment, but consult a doctor. |
| Hepatic Impairment | Not established from the available information. No dose adjustment is typically required for hepatic impairment, but consult a doctor. |
| Maximum Daily Dose | Not applicable. This vaccine is given as a single dose, not daily. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of avaxim 80u pediatric vaccine
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Immunosuppressants | Moderate | |
| Corticosteroids | Moderate |
⚡ Moderate Interactions
- Immunosuppressive therapy
- Corticosteroids (high-dose, systemic)
🍷 Alcohol Interaction
No known interaction with alcohol. However, alcohol consumption may weaken the immune system and reduce the vaccine's effectiveness. It is advisable to avoid excessive alcohol intake around the time of vaccination.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe allergic reaction to a previous dose of any hepatitis A vaccine.","Known hypersensitivity to any component of the vaccine, including neomycin.","Acute severe febrile illness (vaccination should be postponed).","Not for use in individuals with active hepatitis A infection."]
⚠️ Warnings & Precautions
["This vaccine should be administered by a healthcare professional only.","Epinephrine should be readily available in case of anaphylaxis.","Immunocompromised individuals may have a reduced immune response to the vaccine.","The vaccine does not protect against hepatitis B, C, or E.","Vaccination should be postponed during acute severe febrile illness.","Caution in individuals with bleeding disorders or on anticoagulant therapy; use a fine needle and apply pressure to prevent hematoma."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before receiving this vaccine if you are breastfeeding.
💊 Overdose Management
Overdose with this vaccine is unlikely as it is administered as a single dose by a healthcare professional. In case of accidental overdose, monitor the patient for any adverse reactions and provide symptomatic treatment. There is no specific antidote.
⏰ Missed Dose
If a scheduled dose is missed, contact your doctor to reschedule as soon as possible. Do not skip the dose entirely. The booster dose should be given 6 to 12 months after the primary dose; if delayed, it can still be given, but consult your doctor for guidance.
Additional Safety Advice
This medicine should only be administered by a qualified healthcare professional in a setting where emergency equipment is available. Before vaccination, inform your doctor about any allergies, especially to neomycin or other antibiotics, or if the child has a bleeding disorder or is on blood-thinning medication. The vaccine is not recommended during an acute severe febrile illness; minor infections like a cold do not usually require postponement. Pregnancy and breastfeeding: consult your doctor before receiving this vaccine if you are pregnant or breastfeeding, as the safety data are limited. This vaccine does not protect against hepatitis B, C, or E. Continue standard hygiene practices such as handwashing and safe food handling even after vaccination. Keep a record of the vaccination date and the vaccine name for future reference. Do not use this vaccine after the expiry date. Store it in the refrigerator at 2°C to 8°C and do not freeze. If you miss a scheduled dose, contact your doctor to reschedule as soon as possible.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Not established from the available information. Consult a doctor for individualized recommendations.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor about hepatitis A vaccination. The vaccine is not routinely recommended during pregnancy unless the risk of hepatitis A is high.
🏥 Post-Surgery Considerations
No specific considerations. Consult your doctor if surgery is planned around the time of vaccination.
🦷 Dental Procedures
No specific considerations. Inform your dentist about your vaccination status.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions after vaccination. However, if the child experiences fever or fatigue, allow rest and avoid strenuous activities until they feel better.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This vaccine has no impact on daily activities or work. Children can resume normal activities immediately after vaccination, though they may need rest if they develop a mild fever.
🛑 When to Stop This Medicine
There is no need to stop this vaccine; it is given as a single dose or series. If you experience a severe allergic reaction, do not receive further doses without consulting a doctor.
📅 Long-Term Use Effects
Long-term protection against hepatitis A is expected after a complete vaccination series. The vaccine is not associated with any known long-term adverse effects. Booster doses may be recommended in some schedules to ensure durability. Regular monitoring is not required for healthy individuals.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Good handwashing and safe food handling can reduce the risk of hepatitis A but do not replace vaccination.
Evidence: Well-establishedPassive immunization with immunoglobulin can provide short-term protection but is not a substitute for vaccination.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This vaccine can be given simultaneously with other routine vaccines, such as hepatitis B, measles, mumps, rubella, and diphtheria-tetanus-pertussis, at separate injection sites. There are no known interference issues. Consult your doctor for the optimal schedule.
📦 Storage Guide
✅ DO
Store in refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not expose to direct sunlight
✅ DO
Check expiry date before use
❌ DON'T
Do not use if expired
✈️ Traveling with This Medicine
When travelling with this vaccine, carry it in its original packaging with the prescription. It must be stored in a refrigerator at 2°C to 8°C; use a cooler bag with ice packs during travel. Do not freeze. Carry a copy of the vaccination record. If travelling across time zones, no adjustment is needed as it is a single-dose vaccine. Check customs regulations for carrying vaccines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Protective antibodies begin to develop within 2 to 4 weeks after vaccination. Full protection is achieved after the complete series.
A: Vaccination should be postponed during an acute severe febrile illness. Minor infections like a cold do not usually require postponement. Consult your doctor.
A: Safety data in pregnancy are limited. Consult your doctor before receiving this vaccine if you are pregnant.
A: Contact your doctor to reschedule. The booster can still be given if delayed; there is no need to restart the series.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This vaccine can cause hepatitis A.
Fact: The vaccine contains a weakened virus that cannot cause hepatitis A in healthy individuals. - Myth: Once vaccinated, you don't need to practice good hygiene.
Fact: Vaccination is highly effective, but good hygiene practices are still important to prevent other infections. - Myth: The vaccine is only for children.
Fact: It is also recommended for adults at risk, such as travellers and those with chronic liver disease.