Altraday Capsule SR: Comprehensive Guide to Uses, Dosage, and Safety
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual weight gain or swelling
- Severe skin rash with blisters
- Persistent vomiting
If experiencing severe symptoms, call emergency services immediately.
What is acendol-r capsule sr used for?
This medicine is a combination of Aceclofenac 200 mg and Rabeprazole 20 mg used to relieve pain and inflammation in conditions like arthritis while protecting the stomach from acid-related irritation. It is taken once daily with food, and it should not be used by people with active ulcers, severe kidney or liver disease, or during the third trimester of pregnancy.
- Generic Name: Aceclofenac + Rabeprazole
- Manufacturer: Serum Institute Of India Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acendol-r capsule sr के बारे में (Hindi Summary)
उपयोग: यह दवा एसिफेनाक 200 मिलीग्राम और रैबेप्राजोल 20 मिलीग्राम का संयोजन है, जिसका उपयोग गठिया, जोड़ों के दर्द, सूजन और मांसपेशियों के दर्द के इलाज के लिए किया जाता है। यह दर्द और सूजन को कम करने के साथ-साथ पेट में एसिड को नियंत्रित करके पेट की परत की रक्षा करती है। इसे आमतौर पर दिन में एक बार भोजन के साथ लिया जाता है। यह दवा डॉक्टर के परामर्श के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, अपच, पेट दर्द, दस्त या कब्ज, सिरदर्द और चक्कर आना शामिल हैं। कुछ लोगों को त्वचा पर दाने या सूजन भी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन पेट में रक्तस्राव, गुर्दे की समस्या, यकृत की क्षति या गंभीर एलर्जी हो सकती है। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ या तुरंत बाद लें ताकि पेट की जलन कम हो। कैप्सूल को पूरा निगलें, चबाएं या तोड़ें नहीं। शराब और अन्य दर्द निवारक दवाओं से बचें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको गुर्दे, यकृत या हृदय की समस्या है, तो डॉक्टर को बताएं। बिना डॉक्टर की सलाह के दवा बंद न करें और न ही इसकी मात्रा बढ़ाएं।
💊 acendol-r capsule sr Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain, reduces joint inflammation" class="semantic-link" title="Medicines for swelling">swelling, and improves mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Provides symptomatic relief of pain and stiffness while disease-modifying therapy is continued.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Reduces back pain and stiffness associated with inflammatory spine disease.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Used for short-term relief of pain from sprains, strains, and soft-tissue injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Helps manage moderate pain after surgery while protecting the stomach from NSAID-related irritation.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"May be prescribed for painful menstrual cramps when an NSAID is appropriate.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Gout flare","description":"Sometimes used short-term for acute gout pain when other treatments are unsuitable.","evidence":"Limited"},{"condition":"Dental pain","description":"May be used for short-term relief of dental or post-extraction pain.","evidence":"Limited"}]
Primary treatment for: Painful inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
Also treats: Acute musculoskeletal pain, Post-operative pain, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Aceclofenac + Rabeprazole |
| Brand Name | Altraday Capsule SR |
| Manufacturer | Serum Institute Of India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAIDs + Proton Pump Inhibitors |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F) in a dry place. Protect from light and moisture. Keep the capsule in its original container or blister pack until you are ready to take it. Do not store in the bathroom. Keep out of reach of children and pets. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture, but refer to the expiry date printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, especially COX-2, thereby reducing the production of prostaglandins that cause pain, inflammation, and fever. Rabeprazole is a proton-pump inhibitor that irreversibly blocks the hydrogen-potassium ATPase pump in gastric parietal cells, suppressing both basal and stimulated acid secretion. By reducing stomach acid, Rabeprazole helps prevent the gastrointestinal irritation and ulceration that Aceclofenac can cause. The combination does not alter the fundamental pain-relieving action of Aceclofenac but improves its tolerability for the stomach.
Mechanism Steps
💡 How to Take acendol-r capsule sr
Strength: Sustained-release capsule containing Aceclofenac 200 mg and Rabeprazole 20 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one capsule taken orally once daily with or immediately after a meal. The dose may be adjusted by your doctor based on your condition, response to treatment, and kidney or liver function. Do not take more than the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate or change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Close monitoring is advised. Dose must be individualized by a qualified clinician. |
| Renal Impairment | This medicine is not recommended in patients with severe kidney disease (creatinine clearance less than 30 mL/min). In mild to moderate kidney impairment, use with caution and monitor kidney function. Dose adjustment may be needed. Consult your doctor for personalized dosing. |
| Hepatic Impairment | This medicine should be used with caution in patients with liver disease. In mild to moderate liver impairment, dose reduction may be necessary. It is contraindicated in severe liver disease. Consult your doctor for personalized dosing and monitoring. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (Aceclofenac 200 mg + Rabeprazole 20 mg) per day. Do not exceed this dose unless specifically instructed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acendol-r capsule sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Ibuprofen | Major | |
| Methotrexate | Major | |
| Clopidogrel | Major | |
| Corticosteroids | Moderate | |
| Diuretics | Moderate | |
| ACE inhibitors | Moderate | |
| Lithium | Moderate | |
| Ketoconazole | Moderate |
🚨 Major Interactions
- Warfarin and other anticoagulants
- Other NSAIDs including aspirin
- Methotrexate
- Clopidogrel
⚡ Moderate Interactions
- Corticosteroids
- Diuretics and antihypertensives
- Lithium
- Ketoconazole and itraconazole
- Atazanavir and nelfinavir
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol increases the risk of stomach bleeding and ulcers caused by Aceclofenac, and it can also worsen liver toxicity. Additionally, alcohol may increase drowsiness or dizziness. If you drink alcohol regularly, discuss this with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to Aceclofenac, Rabeprazole, or any other NSAID or proton-pump inhibitor","Active or history of recurrent peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney disease (e.g., creatinine clearance less than 30 mL/min)","Severe liver disease","Third trimester of pregnancy","History of asthma, urticaria, or allergic reaction after taking aspirin or other NSAIDs","Coronary artery bypass graft surgery (peri-operative period)"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Do not crush, chew, or break the capsule; swallow it whole.","Avoid alcohol and other NSAIDs while on this medicine.","Use with caution in the elderly due to increased risk of gastrointestinal, kidney, and heart problems.","Do not use for longer than prescribed without medical review.","Inform your doctor if you have a history of ulcers, kidney or liver disease, heart failure, or asthma.","Report any signs of bleeding, such as black stools or vomiting blood, immediately.","Rabeprazole may increase the risk of bone fractures with long-term use; discuss calcium and vitamin D intake with your doctor.","This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not share this medicine with others, even if they have similar symptoms."]
🤱 Lactation Safety
It is not known whether Aceclofenac passes into breast milk in significant amounts. Rabeprazole is excreted in breast milk in small amounts. Because of the lack of sufficient data, this medicine is not recommended during breastfeeding. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose of this medicine may cause severe stomach pain, nausea, vomiting, drowsiness, and gastrointestinal bleeding. If you suspect an overdose, seek immediate medical attention or contact a poison control center. Treatment is supportive and may include activated charcoal, gastric lavage if appropriate, and management of symptoms. There is no specific antidote for Aceclofenac or Rabeprazole. Hemodialysis is not effective for removing Aceclofenac or Rabeprazole from the body.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed, usually once daily with or immediately after a meal to reduce stomach upset. Swallow the capsule whole with a glass of water; do not crush, chew, or break it because it is a sustained-release formulation. Do not take more than the recommended dose or use it for longer than advised without medical review. Avoid alcohol and other NSAIDs such as ibuprofen or aspirin while on this medicine, as they increase the risk of stomach bleeding. Inform your doctor if you have a history of ulcers, kidney or liver disease, heart failure, or asthma. Do not start any new medicine, including herbal products, without checking with your doctor or pharmacist. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep all follow-up appointments and report any black stools, vomiting of blood, severe abdominal pain, or signs of allergy immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events with NSAIDs. They may also be more sensitive to the acid-suppressing effects of Rabeprazole. Use the lowest effective dose for the shortest duration. Regular monitoring of kidney function, liver function, and blood counts is advised. Avoid concomitant use with other NSAIDs or anticoagulants unless specifically prescribed.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. NSAIDs like Aceclofenac may affect ovulation and are not recommended during pregnancy, especially in the third trimester. Rabeprazole should be used only if clearly needed. Your doctor may recommend alternative treatments for pain relief that are safer during pregnancy planning.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery for pain management. However, NSAIDs can increase the risk of bleeding and may interfere with bone healing. Your surgeon will decide if it is appropriate for you. Inform your surgeon about all medicines you are taking. Do not self-medicate after surgery.
🦷 Dental Procedures
If you are scheduled for dental work, inform your dentist that you are taking this medicine. NSAIDs can increase bleeding risk during dental procedures. Your dentist may advise you to stop the medicine temporarily or take precautions. Do not stop without consulting your prescribing doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you have joint pain, low-impact exercises are generally safe, but consult your doctor or physiotherapist for a personalized plan. Stop exercise if you experience severe pain, swelling, or shortness of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Most people can continue their daily activities, but if you experience side effects that interfere with work, consult your doctor. Inform your employer if your job involves operating machinery.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as gastrointestinal bleeding, severe allergic reaction, or kidney problems, stop the medicine and seek immediate medical attention. Your doctor may advise stopping if your symptoms improve or if you develop contraindications. Always follow your doctor's guidance on when to stop.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Rabeprazole, when used for more than a year, has been associated with low magnesium levels, vitamin B12 deficiency, and an increased risk of bone fractures. Regular monitoring of kidney and liver function, magnesium, and vitamin B12 may be advised. The lowest effective dose for the shortest duration is recommended. Do not use for prolonged periods without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedReduces stress on joints and improves osteoarthritis symptoms.
Evidence: Well-establishedMay help relieve chronic pain in some patients.
Evidence: ModerateCan provide local pain relief with fewer systemic side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking. Live vaccines should be avoided if you are on immunosuppressive therapy, but this medicine is not immunosuppressive. Follow your doctor's advice regarding vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, continue taking it at the same interval as prescribed, but consult your doctor for specific advice. Check customs regulations for carrying prescription medicines in your destination country. Always keep it in your carry-on luggage to avoid loss or temperature extremes.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief usually begins within 30 to 60 minutes after taking the capsule, but maximum anti-inflammatory effect may take a few days of regular use.
A: It is best taken with food to reduce the risk of stomach upset. Taking it on an empty stomach may increase the chance of gastric irritation.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, combining with other NSAIDs can increase the risk of gastrointestinal bleeding and kidney problems. Always consult your doctor before taking any other pain reliever.
A: Alcohol should be avoided as it increases the risk of stomach bleeding and liver problems.
A: The duration depends on your condition. It is usually prescribed for short-term relief. Long-term use should be under medical supervision with regular monitoring.
🤔 Common Patient Concerns
🔄 Substitutes for acendol-r capsule sr
View AllAlternative brands with exact same active ingredient:
-
senrab ac 200mg/20mg capsule srSenen Biotech ₹50.63 54.2% CHEAPER
-
dc rab-sr plus capsuleOrion Lifesciences ₹62.58 43.4% CHEAPER
-
aciril r 200mg/20mg capsuleMerril Pharma Pvt Ltd ₹65.00 41.2% CHEAPER
-
Rabidix A 200mg/20mg Capsule SRCaddix Healthcare ₹65.63 40.7% CHEAPER
-
dolostat r 200mg/20mg capsuleBlue Cross Laboratories Ltd ₹66.56 39.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure arthritis.
Fact: This medicine provides symptomatic relief but does not cure arthritis. Disease-modifying treatments and lifestyle changes are also important. - Myth: It is safe to take this medicine without food.
Fact: Taking it with food reduces the risk of stomach upset and ulcers. Always follow your doctor's advice. - Myth: More doses mean faster relief.
Fact: Taking more than prescribed increases the risk of serious side effects without providing extra benefit. - Myth: This medicine is safe to take with other painkillers.
Fact: Combining with other NSAIDs can increase the risk of bleeding and kidney problems. Always consult your doctor.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 200 mg + Rabeprazole 20 mg sustained-release capsules from other manufacturers
Brand Alternatives
- Altraday Capsule SR
- Aceclo-Rab Capsule SR
- Aceclofenac-Rabeprazole Combination Capsules