Atraflox TZ Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Sudden ankle, wrist, or shoulder pain or swelling
- Tingling or numbness in hands or feet
- Seizures
If experiencing severe symptoms, call emergency services immediately.
What is covax oz oral suspension used for?
This medicine is a prescription oral suspension containing Ofloxacin and Ornidazole. It is used to treat mixed bacterial and protozoal infections, including gastrointestinal, gynecological, and dental infections. It works by killing bacteria and protozoa. It should be taken exactly as prescribed, and alcohol must be avoided completely during treatment.
- Generic Name: Ofloxacin + Ornidazole
- Manufacturer: Blubell Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 covax oz oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा ओफ्लोक्सासिन और ओर्निडाजोल का संयोजन है, जिसका उपयोग विभिन्न प्रकार के बैक्टीरियल और प्रोटोज़ोअल संक्रमणों के इलाज के लिए किया जाता है। यह पेट और आंतों के संक्रमण, स्त्री रोग संबंधी संक्रमण, दांतों के संक्रमण और पेट के अंदर के संक्रमण में प्रभावी है। यह दवा बैक्टीरिया और प्रोटोज़ोआ को मारकर काम करती है। इसे डॉक्टर के बताए अनुसार ही लें और कोर्स पूरा करें। शराब का सेवन बिल्कुल न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, सिरदर्द, चक्कर आना और मुंह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभावों में गंभीर दस्त, टेंडन में दर्द या सूजन, हाथ-पैरों में झुनझुनी, दौरे, त्वचा पर गंभीर रैश और लिवर की समस्या शामिल हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। दवा को मापने के लिए दिए गए कप या चम्मच का ही उपयोग करें। इसे भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन भोजन के साथ लेने से पेट की जलन कम होती है। शराब का सेवन बिल्कुल न करें। चक्कर आने पर वाहन न चलाएं। एंटासिड, आयरन या जिंक की दवाओं को इस दवा से 2 घंटे पहले या बाद में लें। कोर्स पूरा करें।
💊 covax oz oral suspension Uses & Benefits
[{"condition":"Mixed aerobic and anaerobic bacterial infections","description":"Used to treat infections caused by a combination of aerobic and anaerobic bacteria, such as intra-abdominal infections, pelvic infections, and dental abscesses.","evidence":"Well-established"},{"condition":"Gastrointestinal infections","description":"Prescribed for infectious diarrhea, dysentery, and other gastrointestinal tract infections where mixed organisms are suspected.","evidence":"Well-established"},{"condition":"Gynecological infections","description":"Used in conditions such as bacterial vaginosis, pelvic inflammatory disease, and post-surgical gynecological infections.","evidence":"Well-established"},{"condition":"Protozoal infections","description":"Ornidazole component is effective against protozoa such as Giardia, Entamoeba, and Trichomonas.","evidence":"Well-established"},{"condition":"Dental infections","description":"Used for dental abscesses and periodontal infections caused by mixed oral flora.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prophylaxis in colorectal surgery","description":"Sometimes used perioperatively to prevent mixed aerobic and anaerobic surgical site infections.","evidence":"Limited"}]
Primary treatment for: Mixed bacterial and protozoal infections
Also treats: Gastrointestinal infections, Gynecological infections, Dental infections, Intra-abdominal infections
📋 Drug Information
| Generic Name(s) | Ofloxacin + Ornidazole |
| Brand Name | Assault Novo 200 mg/500 mg Tablet |
| Manufacturer | Blubell Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibiotic + Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Do not freeze. Keep the bottle tightly closed. Shake well before each use. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two agents with complementary mechanisms. Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Ornidazole is a nitroimidazole that enters susceptible anaerobic bacteria and protozoa, where its nitro group is reduced to reactive intermediates that damage DNA and inhibit nucleic acid synthesis, causing cell death. The combination provides broad coverage against aerobic gram-negative bacteria and anaerobic organisms.
Mechanism Steps
💡 How to Take covax oz oral suspension
Strength: Each 5 mL of suspension contains Ofloxacin 50 mg and Ornidazole 125 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5-10 mL of the suspension orally every 12 hours, or as prescribed by your doctor. The exact dose and duration depend on the type and severity of the infection, your kidney and liver function, and your overall health. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Complete the full course even if you feel better. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially to central nervous system effects and tendon toxicity. Dose adjustment may be necessary based on renal function. Use with caution and monitor closely. |
| Renal Impairment | In patients with renal impairment, dose adjustment of Ofloxacin is required. For creatinine clearance between 20-50 mL/min, the usual dose may be given every 24 hours. For creatinine clearance less than 20 mL/min, the dose may need further reduction. Ornidazole does not require significant adjustment. Consult your doctor for personalized dosing. |
| Hepatic Impairment | In patients with severe hepatic impairment, dose adjustment may be necessary. Ornidazole is metabolized in the liver, and its clearance may be reduced. Use with caution and monitor liver function. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 20 mL of the suspension per day, divided into two doses, or as prescribed by your doctor. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of covax oz oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Theophylline | Major | |
| NSAIDs | Major | |
| Antacids | Major | |
| Alcohol | Major | |
| Caffeine | Moderate | |
| Corticosteroids | Moderate | |
| Oral hypoglycemics | Moderate | |
| Phenytoin | Moderate | |
| Probenecid | Minor |
🚨 Major Interactions
- Warfarin
- Theophylline
- NSAIDs
- Antacids, iron, zinc, sucralfate
- Alcohol
⚡ Moderate Interactions
- Caffeine
- Corticosteroids
- Oral hypoglycemics
- Phenytoin
🍷 Alcohol Interaction
Alcohol must be strictly avoided while taking this medicine and for at least 48 hours after the last dose. Ornidazole can cause a disulfiram-like reaction with alcohol, leading to flushing, severe nausea, vomiting, headache, rapid heartbeat, and low blood pressure. This reaction can be dangerous and requires immediate medical attention if it occurs.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Ofloxacin, Ornidazole, or any other fluoroquinolone or nitroimidazole","Children under 18 years of age (systemic use) unless specifically directed by a specialist","Pregnancy","Breastfeeding","History of tendon disorders related to fluoroquinolone use","Severe liver impairment","Severe renal impairment (dose adjustment required)","Myasthenia gravis (may worsen muscle weakness)"]
⚠️ Warnings & Precautions
["Fluoroquinolones, including Ofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions, including tendinitis, tendon rupture, peripheral neuropathy, and central nervous system effects. Reserve use for patients with no alternative treatment options.","Avoid alcohol during treatment and for 48 hours after the last dose due to disulfiram-like reaction with Ornidazole.","May cause dizziness and lightheadedness. Avoid driving or operating machinery until you know how this medicine affects you.","May cause photosensitivity. Avoid prolonged sun exposure and use sunscreen.","May worsen symptoms of myasthenia gravis. Use with caution.","May cause blood sugar disturbances. Monitor glucose closely in diabetic patients.","Do not use in patients with a history of tendon disorders.","Complete the full course as prescribed to prevent resistance."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding. Both Ofloxacin and Ornidazole are excreted in breast milk and may cause serious adverse reactions in the nursing infant. A decision should be made to either discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, dizziness, and potentially seizures. There is no specific antidote. Treatment should be symptomatic and supportive. Maintain adequate hydration. In case of overdose, seek immediate medical attention or contact a poison control center. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and neurological status.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Shake the bottle well before each use to ensure the medicine is evenly mixed. Measure the dose with the measuring cup or spoon provided, not with a household spoon. Take it with or without food, but taking it with food may reduce stomach upset. Do not skip doses or stop the course early, even if you feel better. Avoid alcohol completely while taking this medicine and for at least 48 hours after the last dose, because alcohol can cause a severe reaction with Ornidazole. Avoid driving or operating heavy machinery if you feel dizzy. Do not take antacids, iron supplements, or zinc supplements within two hours before or after this medicine, as they can reduce absorption. Inform your doctor if you have kidney or liver problems, heart rhythm disorders, or a history of tendon problems. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, central nervous system effects, and renal impairment. Dose adjustment may be necessary based on kidney function. Monitor closely for side effects and consider alternative antibiotics if possible.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. If you are trying to conceive, consult your doctor for safer alternatives. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
This medicine may be used perioperatively to prevent or treat surgical site infections. Inform your surgeon and anesthesiologist if you are taking this medicine. It may interact with other medications used during surgery.
🦷 Dental Procedures
This medicine is often prescribed for dental infections. Inform your dentist if you are taking this medicine before any dental procedure. It may interact with other medications used in dentistry.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you experience dizziness or joint pain. If you notice any tendon pain or swelling, stop exercising and consult your doctor immediately. Light activities like walking are generally safe if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, headache, or fatigue, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how this medicine affects you. Take rest if needed. Inform your employer if your work involves operating machinery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to incomplete treatment, relapse, and antibiotic resistance. If you experience serious side effects such as tendon pain, severe diarrhea, or allergic reactions, stop the medicine and seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended and may lead to antibiotic resistance, fungal overgrowth, and rare but serious effects such as tendon damage, peripheral neuropathy, and liver injury. If prolonged therapy is necessary, regular monitoring of liver and kidney function, blood counts, and neurological status is advised. Always consult your doctor before extending the course.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help prevent antibiotic-associated diarrhea when taken alongside antibiotics, but separate by 2 hours.
Evidence: ModerateEssential for managing dehydration from diarrhea.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines such as the typhoid vaccine. Avoid taking live vaccines during treatment and for several days after. Consult your doctor for specific timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Shake well before each use
❌ DON'T
Do not use if the suspension has changed color or consistency
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it at room temperature and protect it from extreme heat or cold. If crossing time zones, adjust your dosing schedule gradually under medical guidance. Always pack it in your carry-on luggage to avoid loss or temperature extremes. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24-48 hours, but it may take a few days for full effect. Complete the full course as prescribed.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol must be strictly avoided during treatment and for at least 48 hours after the last dose, as it can cause a severe reaction.
A: This medicine is not recommended for children under 18 years for systemic use unless specifically directed by a specialist. Consult a pediatrician.
🤔 Common Patient Concerns
🔄 Substitutes for covax oz oral suspension
View AllAlternative brands with exact same active ingredient:
-
owino z 50 mg/125 mg suspensionAlembic Pharmaceuticals Ltd ₹16.25 58.3% CHEAPER
-
oflokem oz suspensionAlkem Laboratories Ltd ₹18.52 52.5% CHEAPER
-
ornigyl o suspensionTorque Pharmaceuticals Pvt Ltd ₹18.75 51.9% CHEAPER
-
wayflox oz syrupYacca Pharmaceuticals Pvt Ltd ₹19.90 49% CHEAPER
-
Fantim OZ SuspensionGayzel Pharmaceuticals Pvt Ltd ₹29.00 25.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of infection.
Fact: This medicine is effective only against susceptible bacteria and protozoa. It is not effective against viral infections like the common cold or flu. - Myth: I can stop taking this medicine as soon as I feel better.
Fact: You must complete the full course as prescribed, even if symptoms improve, to prevent resistance and relapse. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol must be strictly avoided during treatment and for 48 hours after the last dose due to the risk of a severe disulfiram-like reaction. - Myth: This medicine is safe for children.
Fact: This medicine is not recommended for children under 18 years for systemic use unless specifically directed by a specialist.
🔄 Alternative Options
Generic Alternatives
- Ofloxacin + Ornidazole suspension
Brand Alternatives
- Atraflox TZ Suspension