cosvom-md tablet - Uses, Price, Side Effects & Substitutes
What is cosvom-md tablet used for?
Anset 4mg Tablet MD (Ondansetron) is used to treat GASTRO INTESTINAL. It contains Ondansetron (4mg), which Selective antagonist of serotonin 5-HT3 receptors, blocking serotonin binding in. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ondansetron
- Manufacturer: Cospex Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cosvom-md tablet Uses & Benefits
Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy; prevention of postoperative nausea and vomiting; prevention of radiotherapy-induced nausea and vomiting.
Off-label uses: Treatment of hyperemesis gravidarum; management of pruritus in cholestasis; treatment of serotonin syndrome (limited evidence).
๐ Drug Information
| Generic Name(s) | Ondansetron |
| Brand Name | Anset 4mg Tablet MD |
| Manufacturer | Cospex Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Serotonin antagonists (5-HT3 antagonists) |
| Route of Administration | Oral (tablet, orally disintegrating tablet, oral solution); intravenous; intramuscular. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Selective antagonist of serotonin 5-HT3 receptors, blocking serotonin binding in the chemoreceptor trigger zone (CTZ) and gastrointestinal tract, thereby preventing nausea and vomiting.
Mechanism Steps
๐ก How to Take cosvom-md tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cosvom-md tablet
โ Common Side Effects
- Headache
- Constipation
- Fatigue
- Dizziness
- Diarrhea
๐จ Serious Side Effects
- QT prolongation
- Torsades de pointes
- Serotonin syndrome
- Hypersensitivity reactions (including anaphylaxis)
- Bronchospasm
โ ๏ธ Rare Side Effects
- Transient liver enzyme elevation
- Blurred vision
- Extrapyramidal reactions (dystonia, oculogyric crisis)
- Hypokalemia
- Hypomagnesemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Apomorphine | Major | Increased risk of severe hypotension and loss of consciousness |
| Tramadol | Major | Reduced analgesic efficacy of tramadol; increased risk of serotonin syndrome |
| SSRIs/SNRIs | Major | Increased risk of serotonin syndrome |
| QTc-prolonging agents | Moderate | Additive QT prolongation; risk of torsades de pointes |
| CYP2D6 substrates | Moderate | Reduced metabolism of CYP2D6 substrates; increased toxicity |
| Rifampin | Moderate | Decreased ondansetron plasma concentration; reduced efficacy |
| Ketoconazole | Moderate | Increased ondansetron plasma concentration; increased risk of QT prolongation |
| Antacids | Minor | No significant interaction; may slightly alter absorption |
| Cimetidine | Minor | Minimal effect on ondansetron clearance |
๐จ Major Interactions
- Apomorphine
- Tramadol
- Serotonergic drugs (e.g., SSRIs, SNRIs, MAOIs)
โก Moderate Interactions
- QTc-prolonging agents (e.g., class IA/III antiarrhythmics, certain antipsychotics)
- CYP2D6 substrates (e.g., codeine, metoprolol)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
๐ฝ๏ธ Food Interactions
No significant food interactions; may be taken with or without food.
๐ท Alcohol Interaction
Alcohol may increase sedative effects; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to ondansetron or any component; concomitant use with apomorphine; congenital long QT syndrome.
๐ Monitoring Parameters
ECG (QT interval) in patients at risk; liver function tests if symptoms of hepatotoxicity; electrolyte levels (potassium, magnesium) before IV administration.
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; caution advised; consider risk-benefit.
๐ Overdose Management
Supportive care; monitor ECG for QT prolongation; no specific antidote; hemodialysis not effective.
โฐ Missed Dose
If a dose is missed, take it as soon as remembered unless it is almost time for the next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cosvom-md tablet
View AllAlternative brands with exact same active ingredient (Ondansetron (4mg)):
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medsetron tabletMedley Pharmaceuticals โน4.10 90.3% CHEAPER
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onwon-md tabletZeelab Pharmacy Pvt Ltd โน5.00 88.1% CHEAPER
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monda 4mg injectionMedial Pharma Ltd โน5.25 87.6% CHEAPER
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onsopil 4mg injectionPsychotropics India Ltd โน5.27 87.5% CHEAPER
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vomce 4mg tablet mdComed Chemicals Ltd โน6.25 85.2% CHEAPER
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onsopil 4mg tabletPsychotropics India Ltd โน6.87 83.7% CHEAPER
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onstart 4mg tabletPunjab Formulations Ltd โน7.03 83.3% CHEAPER
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ondace 4mg injectionOaknet Healthcare Pvt Ltd โน7.15 83.1% CHEAPER
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onsetrin 4mg tablet mdSun Pharmaceutical Industries Ltd โน7.90 81.3% CHEAPER
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onswift 4mg tabletInd Swift Laboratories Ltd โน8.34 80.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.