corflam gel - Ibuprofen (NA) medicine

Corflam Gel: Complete Medicine Guide

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🏭 Abaris Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for topical use in musculoskeletal pain.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of face, lips, throat, or difficulty breathing.
  • Severe skin reaction: blistering, peeling, or sores in the mouth.
  • Signs of gastrointestinal bleeding: black, tarry stools or vomiting blood.
  • Decreased urine output or swelling in legs, which may indicate kidney problems.
  • Chest pain, shortness of breath, or weakness, which may indicate a cardiovascular event.
  • Yellowing of skin or eyes, which may indicate liver problems.

If experiencing severe symptoms, call emergency services immediately.

What is corflam gel used for?

This medicine is a topical gel containing ibuprofen, an NSAID used to relieve localized pain and inflammation in muscles and joints. It is applied directly to the skin up to 3-4 times daily.

  • Generic Name: Ibuprofen
  • Manufacturer: Abaris Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 corflam gel के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल जेल है जिसमें आइबुप्रोफेन नामक सक्रिय तत्व होता है। यह मांसपेशियों और जोड़ों के दर्द और सूजन को कम करने के लिए प्रयोग की जाती है। इसे प्रभावित हिस्से पर दिन में 3-4 बार लगाया जाता है। यह मोच, खिंचाव, गठिया और खेल चोटों में आराम देती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में त्वचा पर लालिमा, खुजली या जलन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या गंभीर त्वचा पर चकत्ते हों तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को केवल स्वस्थ त्वचा पर लगाएं। आंखों, होंठों और श्लेष्मा झिल्ली के संपर्क से बचें। लगाने के बाद हाथ धो लें। इसे 7 दिनों से अधिक समय तक बिना डॉक्टर की सलाह के न लगाएं। यदि लक्षण बिगड़ते हैं तो डॉक्टर से संपर्क करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 corflam gel Uses & Benefits

[{"condition":"Musculoskeletal pain","description":"Relieves localized pain and inflammation in muscles, joints, and soft tissues.","evidence":"Well-established"},{"condition":"Sprains and strains","description":"Reduces pain and swelling associated with minor sports injuries.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Provides symptomatic relief for knee and hand osteoarthritis when applied topically.","evidence":"Well-established"},{"condition":"Soft tissue injuries","description":"Helps manage pain from contusions and mild tendonitis.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Neuropathic pain","description":"Sometimes used off-label for localized neuropathic pain, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Musculoskeletal pain

Also treats: Osteoarthritis, Sprains and strains, Soft tissue injuries

📋 Drug Information

Generic Name(s)Ibuprofen
Brand NameAdol 200mg Tablet
ManufacturerAbaris Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from direct sunlight and moisture. Keep the tube tightly closed when not in use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine only to intact skin and avoid broken or irritated areas.
2
Wash your hands thoroughly after applying the gel, unless your hands are the treated area.
3
Do not use this medicine for more than 7 days without consulting a doctor.
4
Avoid covering the treated area with airtight dressings or heat pads.
5
If you are also taking oral NSAIDs, consult your doctor to avoid additive side effects.
6
Stop using the gel and seek medical advice if you develop a severe skin reaction.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Localized joint pain
This medicine is commonly used for this.
Likely Use
✅
Muscle sprain
This medicine can help reduce pain and swelling.
Likely Use
❌
Fever
This medicine is not intended for reducing fever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionIbuprofen is absorbed through the skin when applied topically. The extent of absorption depends on the dose, application area, and skin condition. Typically, only a small fraction of the applied dose reaches the systemic circulation, resulting in low plasma concentrations compared to oral dosing.
DistributionAfter absorption, ibuprofen distributes into the local tissues and to a lesser extent into the bloodstream. It is highly bound to plasma proteins, primarily albumin. The volume of distribution is small, and the drug does not accumulate in the body with topical use.
Protein BindingIbuprofen is approximately 99% bound to plasma proteins, mainly albumin.
MetabolismIbuprofen is metabolized in the liver by cytochrome P450 enzymes, primarily CYP2C9, into inactive metabolites. These metabolites are then excreted.
Half-LifeThe elimination half-life of ibuprofen is approximately 2 hours.
ExcretionIbuprofen and its metabolites are excreted primarily in the urine. A small amount may be excreted in bile and feces.
BioavailabilityThe systemic bioavailability of topical ibuprofen is low, typically less than 10% of the applied dose, depending on the formulation and application site.
Onset of ActionPain relief typically begins within 30 to 60 minutes after application.
Peak Plasma TimePeak plasma concentrations after topical application are generally reached within 2 to 4 hours, but levels are much lower than with oral dosing.
Duration of ActionThe pain-relieving effect of this medicine can last for several hours, and it is usually applied 3 to 4 times daily as needed.

How It Works

This medicine works by inhibiting the cyclooxygenase enzymes, specifically COX-1 and COX-2, which are involved in the production of prostaglandins. Prostaglandins are chemicals that promote inflammation, pain, and fever. By blocking these enzymes, ibuprofen reduces the formation of prostaglandins at the site of application, leading to decreased pain and swelling. Because the gel is applied topically, the effect is largely localized to the underlying tissues, with less systemic exposure than oral ibuprofen.

Mechanism Steps

1
Absorption through the skin: Ibuprofen from the gel penetrates the skin and reaches the underlying muscle and joint tissues.
2
Inhibition of COX enzymes: Ibuprofen binds to and inhibits the COX-1 and COX-2 enzymes in the local tissue.
3
Reduced prostaglandin synthesis: The inhibition of COX enzymes leads to decreased production of prostaglandins, which are mediators of pain and inflammation.
4
Decreased pain and swelling: The reduction in prostaglandins results in less pain, swelling, and inflammation at the site of application.

💡 How to Take corflam gel

Strength: Ibuprofen 5% w/w gel (typical strength; actual strength may vary by product).

1Wash and dry the affected area thoroughly.
2Apply a thin layer of the gel to the affected area.
3Gently massage the gel into the skin until it is absorbed.
4Wash your hands immediately after application, unless your hands are the treated area.
5Do not cover the area with a bandage or dressing unless instructed by your doctor.
6Use the gel only on intact skin and avoid contact with eyes, lips, and mucous membranes.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area up to 3 to 4 times daily, or as directed by your doctor. The dose and frequency depend on the condition being treated and the size of the affected area. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to side effects. Use the lowest effective dose for the shortest duration. Consult a doctor for appropriate dosing.
Renal ImpairmentNo specific dose adjustment is typically required for topical use. However, patients with severe kidney disease should consult a doctor before use.
Hepatic ImpairmentNo specific dose adjustment is typically required for topical use. However, patients with severe liver disease should consult a doctor before use.
Maximum Daily DoseThe maximum daily dose for topical ibuprofen gel is not well established. Do not exceed the recommended application frequency (usually 3-4 times daily) or use for more than 7 days without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Not applicable
This medicine is applied topically and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 If you miss a dose and remember within a few hours
→ Apply the missed dose as soon as you remember.
💡 Continue with your regular schedule.
📌 If it is almost time for your next dose
→ Skip the missed dose and continue with your regular schedule.
💡 Do not apply a double dose to make up for a missed one.

⚠️ Side Effects of corflam gel

✅ Common Side Effects

Application site redness (Common (1-10%))
Usually resolves without treatment. If it persists or worsens, consult a doctor.
Application site itching (Common (1-10%))
Avoid scratching. If itching is severe, stop use and consult a doctor.
Skin rash (Uncommon (0.1-1%))
Discontinue use and consult a doctor if rash develops.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, or difficulty breathing.
Severe skin reaction (e.g., Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop using the gel and seek immediate medical care if you develop a blistering rash, peeling skin, or sores in the mouth.

⚠️ Rare Side Effects

Photosensitivity reaction
Avoid sun exposure to treated areas. If reaction occurs, discontinue use and consult a doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Moderate
Aspirin Moderate
ACE inhibitors Moderate
Diuretics Moderate
Lithium Minor
Methotrexate Minor

🚨 Major Interactions

  • Oral NSAIDs (e.g., aspirin, naproxen)
  • Anticoagulants (e.g., warfarin)

⚡ Moderate Interactions

  • Antihypertensives (e.g., ACE inhibitors, diuretics)
  • Corticosteroids

🍷 Alcohol Interaction

No specific interaction is known between alcohol and topically applied ibuprofen. However, excessive alcohol consumption may increase the risk of gastrointestinal bleeding if any systemic absorption occurs. It is advisable to limit alcohol intake while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to ibuprofen, aspirin, or other NSAIDs.","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.","Application to broken or damaged skin.","Application to eyes, lips, or mucous membranes.","Third trimester of pregnancy.","Children under 12 years of age (unless directed by a doctor)."]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes and mucous membranes.","Do not apply to large areas of skin or use with occlusive dressings.","Do not use for more than 7 days without medical advice.","Consult a doctor if symptoms persist or worsen.","Keep out of reach of children.","Wash hands after application unless hands are being treated.","Avoid sun exposure to treated areas to prevent photosensitivity."]

🤱 Lactation Safety

It is not known whether ibuprofen applied topically passes into breast milk. However, systemic absorption is low. Consult your doctor before using this medicine while breastfeeding. Avoid applying to the breast area.

💊 Overdose Management

Overdose with topical ibuprofen is unlikely due to low systemic absorption. If accidental ingestion occurs, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, abdominal pain, and drowsiness. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Apply this medicine only to intact skin and avoid contact with eyes, lips, and other mucous membranes. Wash your hands thoroughly after applying the gel, unless your hands are the treated area. Do not cover the treated area with airtight dressings or heat pads, as this can increase absorption and the risk of side effects. Do not use this medicine for more than 7 days without consulting a doctor. If your symptoms worsen or do not improve, seek medical advice. Avoid concurrent use with oral NSAIDs unless directed by a doctor. Keep this medicine out of reach of children. Do not use if you are allergic to ibuprofen or any other ingredient. If you are pregnant or breastfeeding, consult your doctor before using this gel.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects of NSAIDs, even topical. Use with caution and consult a doctor if you have kidney, liver, or heart conditions. Monitor for skin irritation.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. NSAIDs may affect ovulation and are generally avoided in the third trimester.

🏥 Post-Surgery Considerations

Consult your surgeon before using this medicine after surgery, especially if you have surgical wounds. Do not apply to broken skin or incisions.

🦷 Dental Procedures

This medicine is not typically used for dental pain. If you have dental pain, consult your dentist for appropriate treatment.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Engage in regular low-impact exercises like swimming or cycling.
😴
Practice good posture to prevent muscle strain.
💧
Include anti-inflammatory foods in your diet, such as fruits and vegetables.
🧘
Get adequate sleep to promote healing and reduce pain perception.
🌞
Apply heat or cold packs as recommended by your physiotherapist.

🏋️ Exercise Considerations

While using this medicine, you can continue with your normal activities as tolerated. However, avoid strenuous exercise or activities that may worsen your injury until pain and swelling have improved. Consult your doctor or physiotherapist before resuming intense physical activity.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce intake of processed and fried foods.
Stay well hydrated by drinking plenty of water.
Consume a balanced diet rich in vitamins and minerals.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any dizziness or drowsiness (rare), avoid these activities until you feel normal. You can continue your daily work activities as tolerated.

🛑 When to Stop This Medicine

Stop using this medicine and consult a doctor if your symptoms do not improve after 7 days, if they worsen, or if you experience any severe side effects such as skin reactions or allergic symptoms. Do not stop prescribed treatment without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine over large areas may increase the risk of systemic side effects similar to oral NSAIDs, including gastrointestinal, kidney, and cardiovascular effects. It is recommended to use the lowest effective dose for the shortest duration. If prolonged use is necessary, regular monitoring of kidney and liver function may be advised by your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve joint function.

Evidence: Well-established
Cold or heat therapy

Applying cold packs can reduce acute swelling, while heat can relax stiff muscles.

Evidence: Well-established
Acupuncture

May provide pain relief for some individuals with musculoskeletal pain.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations while using this gel.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, keep it in its original packaging with the prescription label intact. Carry a copy of your prescription or a letter from your doctor, especially if traveling internationally. Store the gel at room temperature and protect it from extreme heat or cold. If you are crossing time zones, continue applying the gel as needed for pain; there is no strict schedule that requires time zone adjustment. Always check customs regulations regarding topical medications before travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain due to osteoarthritis.
She started using this medicine as prescribed by her doctor. Within two weeks, she noticed significant improvement in her morning stiffness and could walk more comfortably. She emphasized that applying the gel with gentle massage and not covering the area helped her get the best results.
💡 Lesson: Consistent application and proper technique can improve both efficacy and tolerability of topical NSAIDs.
👤 A 30-year-old athlete who suffered an ankle sprain during a football game.
He applied this medicine to his ankle three times a day. The pain and swelling reduced considerably within three days, allowing him to return to light training. He made sure to rest and elevate his ankle as advised by his physiotherapist.
💡 Lesson: Topical ibuprofen can be effective for acute soft tissue injuries when combined with rest and elevation.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts relieving pain within 30 to 60 minutes after application.

Q: Can I use this gel on my face?

A: No, this gel should not be applied to the face or near eyes, lips, or mucous membranes.

Q: Is it safe to use during pregnancy?

A: Consult your doctor before using this medicine during pregnancy, especially in the third trimester.

Q: Can I take oral ibuprofen while using this gel?

A: Consult your doctor before combining oral and topical NSAIDs to avoid additive side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after applying this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while using this?

🔄 Substitutes for corflam gel

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Topical ibuprofen is completely safe and has no side effects.
    Fact: While side effects are less common than with oral NSAIDs, topical ibuprofen can still cause skin irritation and, rarely, allergic reactions.
  • Myth: You can apply this gel to any part of the body.
    Fact: This gel should only be applied to intact skin and must be kept away from eyes, lips, and mucous membranes.
  • Myth: More gel means faster relief.
    Fact: Applying more than the recommended amount does not improve efficacy and may increase the risk of side effects.

🔄 Alternative Options

Generic Alternatives

  • Ibuprofen gel 5% w/w
  • Ibuprofen topical gel

Brand Alternatives

  • Corflam gel

📊 Comparison with Similar Medicines

[{"medicine":"Ibuprofen gel","class":"NSAID","route":"Topical","common_use":"Musculoskeletal pain"},{"medicine":"Diclofenac gel","class":"NSAID","route":"Topical","common_use":"Osteoarthritis, soft tissue injuries"},{"medicine":"Ketoprofen gel","class":"NSAID","route":"Topical","common_use":"Musculoskeletal pain"}]

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