constiluc laxative sugar free - Sodium Picosulfate (3.33mg) + Liquid Paraffin (1.25ml) medicine

Avolax Oral Suspension: Complete Medicine Guide

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🏭 Lucrose Pharma Private Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for short-term constipation; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is constiluc laxative sugar free used for?

This medicine is a combination laxative containing sodium picosulfate and liquid paraffin. It is used for short-term relief of constipation. It works by stimulating the colon and lubricating the stool. It should not be used for more than 7 days without medical advice.

  • Generic Name: Sodium Picosulfate + Liquid Paraffin
  • Manufacturer: Lucrose Pharma Private Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 constiluc laxative sugar free के बारे में (Hindi Summary)

उपयोग: यह दवा कब्ज के इलाज के लिए इस्तेमाल की जाती है। इसमें सोडियम पिकोसल्फेट और लिक्विड पैराफिन होते हैं, जो मल को नरम करके और आंतों को उत्तेजित करके मल त्याग को आसान बनाते हैं। यह अल्पकालिक उपयोग के लिए है और इसे डॉक्टर की सलाह के बिना 7 दिनों से अधिक नहीं लेना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में पेट में ऐंठन, जी मिचलाना, दस्त और गैस शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज पेट दर्द, इलेक्ट्रोलाइट असंतुलन और एलर्जी प्रतिक्रिया शामिल हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। दिन भर पर्याप्त पानी पिएं। बिना डॉक्टर की सलाह के 7 दिनों से अधिक न लें। अन्य दवाओं के साथ लेने से पहले कम से कम 2 घंटे का अंतराल रखें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 constiluc laxative sugar free Uses & Benefits

[{"condition":"Constipation","description":"Short-term relief of occasional constipation when stimulant and lubricant laxatives are needed together.","evidence":"Well-established"},{"condition":"Bowel preparation","description":"Sometimes used as part of bowel cleansing regimens before certain procedures, though not a standard first-line agent.","evidence":"Limited"}]

Off-label uses: [{"condition":"Opioid-induced constipation","description":"May be used off-label when other laxatives are insufficient, but requires medical supervision.","evidence":"Limited"}]

Primary treatment for: Constipation

Also treats: Irregular bowel habits, Fecal impaction (adjunct)

📋 Drug Information

Generic Name(s)Sodium Picosulfate + Liquid Paraffin
Brand NameAvolax Oral Suspension
ManufacturerLucrose Pharma Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassStimulant Laxative + Emollient Laxative
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place. Protect from direct sunlight. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at bedtime to allow it to work overnight.
2
Drink plenty of water throughout the day to help soften the stool.
3
Do not use this medicine for more than 7 days without consulting your doctor.
4
Separate this medicine from other medications by at least 2 hours to avoid absorption issues.
5
If you experience severe abdominal pain or rectal bleeding, stop the medicine and seek medical help immediately.
6
Avoid alcohol while taking this medicine to prevent dehydration.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

❌
Chronic joint pain
This medicine is not for pain relief.
Not Primary
❌
Fever
This medicine is not a fever reducer.
Not Primary
✅
Constipation
This medicine is commonly prescribed for this.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSodium picosulfate is minimally absorbed from the gastrointestinal tract; it acts locally in the colon. Liquid paraffin is not absorbed to a significant extent; it remains in the gut lumen.
DistributionSodium picosulfate: due to minimal absorption, systemic distribution is negligible. Liquid paraffin: remains in the gastrointestinal tract and is not distributed systemically.
Protein BindingNot established from the available information.
MetabolismSodium picosulfate is metabolized by colonic bacteria to its active metabolite. Liquid paraffin is not metabolized; it is excreted unchanged in feces.
Half-LifeNot established from the available information.
ExcretionSodium picosulfate and its metabolites are primarily excreted in feces. Liquid paraffin is excreted entirely in feces.
BioavailabilitySodium picosulfate: negligible systemic bioavailability when taken orally. Liquid paraffin: not absorbed.
Onset of ActionSodium picosulfate typically produces a bowel movement within 6 to 12 hours. Liquid paraffin acts within 6 to 8 hours.
Peak Plasma TimeNot applicable due to minimal systemic absorption.
Duration of ActionThe effect of a single dose usually lasts until a bowel movement occurs, typically within 6 to 12 hours.

How It Works

Sodium picosulfate is a stimulant laxative that acts locally in the colon. It is hydrolyzed by colonic bacteria to the active metabolite, which directly stimulates the enteric nervous system and colonic smooth muscle, increasing peristaltic contractions and promoting water and electrolyte secretion into the bowel. Liquid paraffin is a lubricant laxative that coats the stool and intestinal wall with a waterproof film, softening the stool and facilitating its passage. Together, they provide both stimulant and lubricant effects for constipation relief.

Mechanism Steps

1
Activation of sodium picosulfate: Sodium picosulfate is converted by colonic bacteria into its active form, which stimulates the enteric nervous system.
2
Stimulation of colonic motility: The active metabolite increases peristaltic contractions in the large intestine, moving stool forward.
3
Increased water and electrolyte secretion: Sodium picosulfate promotes secretion of water and electrolytes into the colon, softening the stool.
4
Lubrication by liquid paraffin: Liquid paraffin forms a waterproof film on the stool and intestinal wall, reducing friction and easing passage.

💡 How to Take constiluc laxative sugar free

Strength: Each 5 mL contains Sodium Picosulfate 3.33 mg and Liquid Paraffin 1.25 mL.

1Shake the bottle well before each use.
2Measure the dose accurately using the provided measuring cup or spoon.
3Take the medicine orally, preferably at bedtime.
4Drink a full glass of water after taking the dose.
5Follow with adequate fluid intake throughout the day.

Dosage Information

Adult DosageThe usual adult dose is 5-10 mL of the oral suspension, taken at bedtime or as directed by a physician. The dose may be adjusted based on response and tolerability. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of laxatives. Start with a lower dose and monitor for dehydration and electrolyte imbalance. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Monitor electrolytes and hydration status. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. No specific dose adjustment established. Consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose is 10 mL of the oral suspension, but this should not be exceeded without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of constiluc laxative sugar free

✅ Common Side Effects

Abdominal cramps (Common (5-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Nausea (Common (5-10%))
Take with food or milk to reduce nausea. Consult doctor if it continues.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or lasts more than 24 hours, contact your doctor.
Flatulence (Common (5-10%))
Usually temporary. Avoid carbonated drinks to reduce gas.
Anal irritation (Uncommon (1-5%))
Keep the area clean and dry. Consult doctor if irritation persists.

🚨 Serious Side Effects

Severe abdominal pain (Rare (<0.1%))
Seek immediate medical attention.
Electrolyte imbalance (Rare (<0.1%))
Symptoms include muscle weakness, confusion, or irregular heartbeat. Seek immediate medical attention.
Allergic reaction (Rare (<0.1%))
Symptoms include rash, itching, swelling, dizziness, or difficulty breathing. Seek emergency help.
Rectal bleeding (Rare (<0.1%))
Stop use and consult a doctor immediately.

⚠️ Rare Side Effects

Lipoid pneumonia
Seek immediate medical attention if you develop chest pain, cough, or difficulty breathing.
Vitamin deficiency (A, D, E, K)
Consult doctor for monitoring if long-term use is necessary.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Oral contraceptives Major
Digoxin Moderate
Levothyroxine Moderate
Fat-soluble vitamins Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Oral contraceptives
  • Fat-soluble vitamins (A, D, E, K)

⚡ Moderate Interactions

  • Digoxin
  • Levothyroxine

🍷 Alcohol Interaction

Alcohol may worsen dehydration and electrolyte imbalance caused by laxatives. Avoid excessive alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Intestinal obstruction or ileus","Acute abdominal pain of unknown cause","Severe inflammatory bowel disease","Known hypersensitivity to sodium picosulfate or liquid paraffin","Children under 12 years (unless prescribed by a doctor)"]

⚠️ Warnings & Precautions

["Do not use for more than 7 days without medical advice.","Avoid in patients with difficulty swallowing or risk of aspiration due to liquid paraffin.","Use with caution in elderly and debilitated patients.","May cause dependence with prolonged use.","Separate from other medications by at least 2 hours.","Drink adequate fluids to prevent dehydration."]

🤱 Lactation Safety

It is not known whether sodium picosulfate or liquid paraffin pass into breast milk. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose may cause severe diarrhea, dehydration, and electrolyte imbalance. Seek immediate medical attention. Treatment is supportive and symptomatic, including fluid and electrolyte replacement.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Drink plenty of water throughout the day to help soften the stool and prevent dehydration. Avoid taking this medicine for more than 7 days without medical advice. Do not take it at the same time as other medicines, as liquid paraffin can reduce their absorption; separate by at least 2 hours. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine if you have abdominal pain, nausea, or vomiting without consulting a doctor. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to dehydration and electrolyte imbalance. Use with caution and monitor fluid intake. Lower doses may be appropriate.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are planning to become pregnant. It should only be used if clearly needed.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, especially abdominal surgery, as it may affect healing.

🦷 Dental Procedures

No specific precautions. Inform your dentist if you are taking this medicine.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce pressure on the intestines.
🥗
Regular low-impact exercise like walking or swimming.
😴
Practice good bowel habits, such as going at the same time each day.
💧
Include fiber-rich foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

No specific exercise restrictions. However, if you experience dizziness or weakness due to dehydration, avoid strenuous exercise until you feel better.

🥗 Diet Recommendations

Include fiber-rich foods like fruits, vegetables, and whole grains
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause dizziness or abdominal cramps. Avoid driving or operating heavy machinery if you feel unwell. It is best to take it at bedtime to minimize impact on daily activities.

🛑 When to Stop This Medicine

Stop taking this medicine if you experience severe abdominal pain, rectal bleeding, or allergic reactions. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to laxative dependence, electrolyte imbalance, and reduced absorption of fat-soluble vitamins. It should only be used short-term unless directed by a doctor. Regular monitoring may be needed if prolonged use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary fiber

Increasing fiber intake can help relieve constipation naturally.

Evidence: Well-established
Physical activity

Regular exercise can stimulate bowel movements.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, continue taking at your usual bedtime. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic constipation
Started this medicine as prescribed for occasional constipation. Within 8 hours noticed a bowel movement without straining. Emphasized taking it at bedtime and drinking plenty of water.
💡 Lesson: Taking the medicine at bedtime and staying hydrated improves efficacy and reduces discomfort.
👤 A 60-year-old woman with constipation due to medications
Used this medicine for short-term relief. Experienced mild abdominal cramps that resolved after the first dose. Advised to separate from her thyroid medication by 4 hours.
💡 Lesson: Separating from other medicines is crucial to avoid interactions.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually produces a bowel movement within 6 to 12 hours after taking it.

Q: Can I take it every day?

A: It should not be used for more than 7 days without medical advice. Prolonged use can lead to dependence.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for constiluc laxative sugar free

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Laxatives are safe for long-term use.
    Fact: Long-term use can lead to dependence and electrolyte imbalance. Use only as directed.
  • Myth: More laxative means faster relief.
    Fact: Taking more than the recommended dose can cause severe diarrhea and dehydration.

🔄 Alternative Options

Generic Alternatives

  • Sodium picosulfate + liquid paraffin oral suspension (generic)

Brand Alternatives

  • Avolax Oral Suspension

📊 Comparison with Similar Medicines

[{"medicine":"Avolax Oral Suspension","active_ingredient":"Sodium picosulfate + liquid paraffin","onset":"6-12 hours","route":"Oral"},{"medicine":"Lactulose","active_ingredient":"Lactulose","onset":"24-48 hours","route":"Oral"},{"medicine":"Bisacodyl","active_ingredient":"Bisacodyl","onset":"6-12 hours","route":"Oral"}]

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