conil p syrup - Phenylpropanolamine (8mg) + Chlorpheniramine Maleate (1.5mg) medicine

conil p syrup

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🏭 Sifam Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

What is conil p syrup used for?

This medicine contains Phenylpropanolamine (8mg) + Chlorpheniramine Maleate (1.5mg) and is used to treat RESPIRATORY. Phenylpropanolamine: alpha-adrenergic agonist causing vasoconstriction and decongestion; Chlorphenir. Always consult your doctor before use.

  • Generic Name: Phenylpropanolamine + Chlorpheniramine Maleate
  • Manufacturer: Sifam Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 conil p syrup Uses & Benefits

Symptomatic relief of nasal congestion, rhinorrhea, sneezing due to common cold, allergic rhinitis, sinusitis

Off-label uses: Weight loss (Phenylpropanolamine historically used)

📋 Drug Information

Generic Name(s)Phenylpropanolamine + Chlorpheniramine Maleate
Brand NameAxn Syrup
ManufacturerSifam Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassSympathomimetic + Antihistamine
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract
DistributionWidely distributed; crosses blood-brain barrier
Protein BindingPhenylpropanolamine: ~20%; Chlorpheniramine: ~70%
MetabolismHepatic via CYP450 enzymes
Half-LifePhenylpropanolamine: 3-5 hours; Chlorpheniramine: 12-15 hours
ExcretionRenal (urine)
BioavailabilityPhenylpropanolamine: ~100%; Chlorpheniramine: ~25-50%
Onset of Action15-30 minutes
Peak Plasma Time1-2 hours
Duration of Action4-6 hours

How It Works

Phenylpropanolamine: alpha-adrenergic agonist causing vasoconstriction and decongestion; Chlorpheniramine: H1-receptor antagonist blocking histamine effects

Mechanism Steps

1Phenylpropanolamine stimulates alpha-adrenergic receptors in nasal mucosa, causing vasoconstriction and reducing congestion.
2Chlorpheniramine competitively blocks H1 receptors, preventing histamine-mediated vasodilation, increased capillary permeability, and sensory nerve stimulation.
3Combination provides both decongestant and antihistamine effects for symptomatic relief.

💡 How to Take conil p syrup

Follow your doctor's prescription exactly.

⚠️ Side Effects of conil p syrup

✅ Common Side Effects

Drowsiness
Dry mouth
Nervousness
Insomnia
Dizziness

🚨 Serious Side Effects

Hypertension
Arrhythmias
Seizures
Urinary retention
Allergic reactions

⚠️ Rare Side Effects

Hemolytic anemia
Thrombocytopenia
Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major Hypertensive crisis
Beta-blockers Major Reduced antihypertensive effect
Antihypertensives Major Reduced blood pressure control
CNS depressants Moderate Enhanced sedation
Anticholinergics Moderate Increased anticholinergic effects
Tricyclic antidepressants Moderate Increased sympathomimetic effects
Antacids Minor Possible altered absorption
Caffeine Minor Additive stimulant effect

🚨 Major Interactions

  • MAOIs
  • Beta-blockers
  • Antihypertensives

⚡ Moderate Interactions

  • CNS depressants
  • Anticholinergics
  • Tricyclic antidepressants

🍷 Alcohol Interaction

Increased CNS depression

🛡️ Safety & Warnings

🚫 Contraindications

Hypertension, cardiovascular disease, hyperthyroidism, glaucoma, MAOI use, urinary retention

🤱 Lactation Safety

Caution; excreted in breast milk

💊 Overdose Management

Supportive care; activated charcoal if recent ingestion; monitor vital signs; treat hypertension with phentolamine; treat CNS depression with supportive measures

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose

🔄 Substitutes for conil p syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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